
DOI . ORG {
}
Title[redir]:
The Spemann organizer gene, Goosecoid, promotes tumor metastasis | PNAS
Description:
The process of invasion and metastasis during tumor progression is often reminiscent of cell migration events occurring during embryonic development. We hypothesized that genes controlling cellular...
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Keywords {🔍}
cells, gsc, cell, google, scholar, expression, pubmed, crossref, cancer, tumor, human, goosecoid, research, breast, metastasis, epithelial, fig, samples, control, organizer, gene, expressing, mice, mrna, tgfβ, shown, hmecs, tumors, emt, institute, spemann, view, normal, data, gfp, mdamb, article, metastatic, cambridge, biol, results, embryonic, genes, transcription, tissue, levels, number, gscexpressing, articles, information,
Topics {✒️}
quantitative real-time rt-pcr gsc-expressing mda-mb-231 cells supporting information 08636table1 wnt/β-catenin signaling pathways madin–darby canine kidney rnase-free dnase set social media facebook mda-mb-231 cells acquired mda-mb-231 cells expressing mda-mb-231 cell line supporting information sybr-green detection reagent authors affiliations kimberly methods rna preparation patient-matched normal tissue wnt/β-catenin signaling sloan–kettering cancer center jan-willem van ittersum wnt/β-catenin pathway topflash/fopflash reporter system health grant r01-ca078461 activated tgf-β1 ligand gsc-expressing cells grew δn90 β-catenin consisting epithelial–mesenchymal transition hmec gsc-expressing hmec cells gfp-labeled lung metastases current emotional state gsc-specific primer pairs female nod-scid mice mesenchymal proteins n-cadherin mesenchymal protein n-cadherin tgf-β signaling human breast cancer patient-matched sample sophisticated auditory–motor learning epithelial proteins e-cadherin cold spring harbor tgf-β superfamily em de robertis breast cancer cells massachusetts general hospital human tgfβ type neural crest development breast cancer detectable gsc-expressing cells compared related mesoderm-inducing signals expressing substantial amounts human breast tumors human breast cells
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