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app, signalling, wnt, pubmed, article, wntpcp, production, dkk, google, scholar, cas, fasudil, synapse, wntβcatenin, activity, fig, loss, lrp, vangl, cell, cells, data, protein, alzheimers, amyloid, disease, canonical, pathway, central, effects, wnta, neurons, nature, dendritic, treatment, noncanonical, mice, previously, shown, heka, enhanced, activation, swedish, binding, expression, cognitive, brain, reduced, reporter, measured,

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nature portfolio privacy policy wnt3a-driven wnt-β-catenin signalling advertising selectively activated wnt-β-catenin c-jun n-terminal kinase wnt/beta-catenin pathway represses wnt-β-catenin signalling drove scientific procedures nature 325 nature 353 nature 407 nature geriatric research education favour wnt-β-catenin signalling potentiate wnt-β-catenin signalling wnt-β-catenin signalling activity promotes wnt-β-catenin signalling wnt/β-catenin signaling pathway beta-amyloid-induced hippocampal neurodegeneration solutions reprints control wild-type-expressing cells wnt-β-catenin pathway21 research progress research & therapy jnk/c-jun arm wnt5a-driven wnt-pcp signalling wnt-pcp molecular machinery9 nonsteroidal anti-inflammatory drugs wnt/β-catenin signaling mouse anti-app/aβ antibody wnt-β-catenin signalling pathogenic-positive feedback loop β-secretase cleavage site transcription factor nfe2l2/nrf2 beta-amyloid precursor protein amyloid beta-protein involves wnt-β-catenin pathway tcf/lef transcriptional activity β-amyloid precursor protein martin broadstock author information authors triple-transgenic model aβ-driven synapse loss wnt/mapk signaling pathway coated pit-mediated internalization clathrin-coated vesicles purified wnt-pcp signalling induced favour wnt-pcp signalling

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      name:Paul Simons
      url:http://orcid.org/0000-0002-5007-6674
      affiliation:
            name:University College London
            address:
               name:Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Royal Free Campus, University College London, London, UK
               type:PostalAddress
            type:Organization
      name:Richard Killick
      url:http://orcid.org/0000-0002-8815-3436
      affiliation:
            name:King’s College London
            address:
               name:Maurice Wohl Clinical Neuroscience Institute, King’s College London, London, UK
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Maurice Wohl Clinical Neuroscience Institute, King’s College London, London, UK
      name:Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Investigación Sanitaria La Paz (IdiPaz), Autonomous University of Madrid (UAM), Madrid, Spain
      name:Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK
      name:Maurice Wohl Clinical Neuroscience Institute, King’s College London, London, UK
      name:Boston University School of Medicine, Boston, USA
      name:Department of Veterans Affairs, Geriatric Research Education and Clinical Center, Bedford, USA
      name:Boston University School of Medicine, Boston, USA
      name:Department of Veterans Affairs, Geriatric Research Education and Clinical Center, Bedford, USA
      name:Boston University School of Medicine, Boston, USA
      name:Department of Veterans Affairs, Geriatric Research Education and Clinical Center, Bedford, USA
      name:Institute of Cardiovascular and Medical Science, University of Glasgow, Glasgow, Scotland
      name:Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Investigación Sanitaria La Paz (IdiPaz), Autonomous University of Madrid (UAM), Madrid, Spain
      name:Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Royal Free Campus, University College London, London, UK
      name:University of Exeter Medical School, Exeter, UK
      name:Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Royal Free Campus, University College London, London, UK
      name:Maurice Wohl Clinical Neuroscience Institute, King’s College London, London, UK

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