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nature portfolio research ethics committee privacy policy cd3−cd19+cd20+cd27+ antigen-experienced cd19+cd20+cd27+ antigen-experienced high-throughput single-cell sequencing influenza-specific lung-resident memory advertising nature https research sars-cov-2 spike-specific cd8+/cd69+ nature 547 nature represent sars-cov-2-specific cd8+ cd3−cd19+cd20+cd27+ aebcs hill diversity index found sars-cov-2-specific shuffling produce high-affinity memory reprints rearranged full-length bcr/tcr reagent kits library single-cell immune profiling specific t-cell subsets sars-cov-2-specific humoral cd19+cd20+cd27+ aebcs gd t-cell subsets t-cell immune memory distinct t-cell subsets cn/yzygj/s7653p/202003/46c9294a7dfe4cef80dc7f5912eb1989 robust t-cell memory inducing t-cell response �leukocyte cell-cell adhesion” robust t-cell responses future vaccine development �b-cell-mediated immunity t-cell ifn response /single-cell-vdj/datasets/3 /single-cell-vdj/datasets/2 single-cell rna sequencing memory b-cell subsets group-specific color scheme t-cell subsets based dimensional t-sne visualization cd3+ t-cell populations potential t-cell epitopes t-cell immune repertoires inflammatory monocyte-macrophage responses social media patients showed pao2/fio2 ≤ 300 mmhg

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