
NCBI . NLM . NIH . GOV {
}
Title[redir]:
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes - PMC
Description:
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) characterized by autoimmune mediated demyelination and neurodegeneration. The CNS of patients with MS harbors expanded clones of antigen-experienced B cells that ...
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Keywords {🔍}
cns, cells, doi, cell, tissue, cln, google, scholar, fig, pubmed, multiple, compartments, sequences, clones, clonal, sclerosis, lymphoid, pmc, lineage, article, sequencing, secondary, free, maturation, repertoire, observed, periphery, brain, expanded, peripheral, antigen, clns, members, compartment, trees, patients, data, number, analysis, found, subject, igg, table, sequence, distribution, multicompartment, csf, clonally, present, founders,
Topics {✒️}
post-germinal center reaction high-throughput sequencing results include post-translational modifications ectopic b-cell follicles pmc beta search antigen-driven maturation originates express pro-inflammatory cytokines flow cytometry-based sorting protein array-based profiling meningeal b-cell follicles sci transl med relapsing-remitting multiple sclerosis t-cell receptor expression raw read processing effective antigen-presenting cells peripheral b-cell responses ms antigen-specific response high-throughput sequencing anti-inflammatory regulatory role high-throughput arrays high throughput platform rare tissue collections central nervous system multi-compartment lineage trees primary amplification bias multi-compartment clonal members unmutated single-tissue founders primary progressive ms applied high-throughput [google scholar] 49 [google scholar] 50 [google scholar] immune infiltrate initiates selecting unique reads receives speaking fees varicella zoster virus chronic multiple sclerosis functioning immune system myelin surface antigen b-lymphocyte contributions complex network research chronic immune response methods mol biol conventional sequencing shows myelin-derived antigens b-cell homing cell clonal populations secondary lymphoid organs oligoclonal bands connect antigen-driven selection
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- https://doi.org/10.1016/j.cell.2013.10.034's financial summary
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- https://doi.org/10.1002/eji.201142108's total income per month
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- What are the total earnings of https://scholar.google.com/scholar_lookup?journal=Mult%20Scler&title=Disappearance%20of%20cerebrospinal%20fluid%20oligoclonal%20bands%20after%20natalizumab%20treatment%20of%20multiple%20sclerosis%20patients&author=F%20von%20Glehn&author=AS%20Farias&author=AC%20de%20Oliveira&author=A%20Damasceno&author=AL%20Longhini&volume=18&publication_year=2012&pages=1038-1041&pmid=22041091&doi=10.1177/1352458511428465&?
- https://doi.org/10.1177/1352458512463483's revenue stream
- How much cash flow does https://scholar.google.com/scholar_lookup?journal=Mult%20Scler&title=Cerebrospinal%20fluid%20parameters%20of%20B%20cell-related%20activity%20in%20patients%20with%20active%20disease%20during%20natalizumab%20therapy&author=A%20Harrer&author=H%20Tumani&author=S%20Niendorf&author=F%20Lauda&author=C%20Geis&volume=19&publication_year=2013&pages=1209-1212&pmid=23093485&doi=10.1177/1352458512463483& have monthly?
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- How much does https://scholar.google.com/scholar_lookup?journal=Arch%20Neurol&title=Immunological%20markers%20of%20optimal%20response%20to%20natalizumab%20in%20multiple%20sclerosis&author=LM%20Villar&author=MI%20Garcia-Sanchez&author=L%20Costa-Frossard&author=M%20Espino&author=E%20Roldan&volume=69&publication_year=2012&pages=191-197&pmid=22332187&doi=10.1001/archneurol.2011.971& pull in monthly?
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