We are analyzing https://link.springer.com/chapter/10.1007/978-1-4939-2095-2_10.

Title:
A Systems Biology Approach to Iron Metabolism | SpringerLink
Description:
Iron is critical to the survival of almost all living organisms. However, inappropriately low or high levels of iron are detrimental and contribute to a wide range of diseases. Recent advances in the study of iron metabolism have revealed multiple intricate pathways...
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Science
Health & Fitness

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 7,625,932 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure how the site profits.

The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Link.springer.com might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

pubmed, google, scholar, article, cas, iron, central, hepcidin, blood, cell, metabolism, biology, homeostasis, cancer, transferrin, chapter, molecular, biol, systems, regulation, nat, protein, genet, transporter, expression, human, ferroportin, approach, andrews, heme, metab, usa, content, torti, cellular, receptor, sci, chem, nature, hemochromatosis, privacy, essential, cookies, information, publish, medicine, regulatory, gene, hereditary, proc,

Topics {✒️}

iron-responsive element/iron-regulatory protein month download article/chapter correct 59fe-distribution kinetics rapid dose-dependent hypoferremia transferrin-induced hepcidin expression il-6-gp130-dependent activation transferrin-bound iron uptake iron exporter ferroportin/slc40a1 hentze mw iron-overload-related disease duodenal iron-regulated transporter mouse liver-specific gene privacy choices/manage cookies hepcidin-induced internalization andrews nc annu rev physiol device instant download heme export protein bmc syst biol severe juvenile hemochromatosis hepcidin-induced endocytosis ferroportin requires binding inhibits hepcidin activation computational models based bmc med genomics tissue-specific subnetworks il-6 mediates hypoferremia connecticut health center exhibits antimicrobial activity body iron homeostasis wake forest school severe iron overload human duodenal cytochrome hereditary hemochromatosis due hfe hereditary hemochromatosis cytokine-hepcidin link european economic area mhc class i zebrafish fpn1 identifies intestinal brush border biochim biophys acta key endogenous regulator serine protease matriptase-2 muckenthaler mu author information authors editor information editors mammalian iron metabolism iron behaving badly inappropriate iron chelation intestinal iron transport

Questions {❓}

When is a heme transporter not a heme transporter?

Schema {🗺️}

ScholarlyArticle:
      headline:A Systems Biology Approach to Iron Metabolism
      pageEnd:225
      pageStart:201
      image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4939-2095-2.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:A Systems Biology Approach to Blood
         isbn:
            978-1-4939-2095-2
            978-1-4939-2094-5
         type:Book
      publisher:
         name:Springer New York
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Julia Chifman
            affiliation:
                  name:Wake Forest School of Medicine
                  address:
                     name:Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Reinhard Laubenbacher
            affiliation:
                  name:University of Connecticut Health Center
                  address:
                     name:Center for Quantitative Medicine, University of Connecticut Health Center, Farmington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Suzy V. Torti
            affiliation:
                  name:University of Connecticut Health Center
                  address:
                     name:Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:Hydroxyl radical, Heme, Phagocytose, Constant decay rate, Petri nets, Homeostasis, Transferrin, Erythroid bone marrow, Erythrocytes, Phagocytosis, Plasma, Continuous versus discrete models
      description:Iron is critical to the survival of almost all living organisms. However, inappropriately low or high levels of iron are detrimental and contribute to a wide range of diseases. Recent advances in the study of iron metabolism have revealed multiple intricate pathways that are essential to the maintenance of iron homeostasis. Further, iron regulation involves processes at several scales, ranging from the subcellular to the organismal. This complexity makes a systems biology approach crucial, with its enabling technology of computational models based on a mathematical description of regulatory systems. Systems biology may represent a new strategy for understanding imbalances in iron metabolism and their underlying causes.
      datePublished:2014
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
      context:https://schema.org
Book:
      name:A Systems Biology Approach to Blood
      isbn:
         978-1-4939-2095-2
         978-1-4939-2094-5
Organization:
      name:Springer New York
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Wake Forest School of Medicine
      address:
         name:Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, USA
         type:PostalAddress
      name:University of Connecticut Health Center
      address:
         name:Center for Quantitative Medicine, University of Connecticut Health Center, Farmington, USA
         type:PostalAddress
      name:University of Connecticut Health Center
      address:
         name:Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Julia Chifman
      affiliation:
            name:Wake Forest School of Medicine
            address:
               name:Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, USA
               type:PostalAddress
            type:Organization
      name:Reinhard Laubenbacher
      affiliation:
            name:University of Connecticut Health Center
            address:
               name:Center for Quantitative Medicine, University of Connecticut Health Center, Farmington, USA
               type:PostalAddress
            type:Organization
      name:Suzy V. Torti
      affiliation:
            name:University of Connecticut Health Center
            address:
               name:Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, USA
      name:Center for Quantitative Medicine, University of Connecticut Health Center, Farmington, USA
      name:Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(327)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js

4.29s.

LINK . SPRINGER . COM {}