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cells, nrf, aldhh, cancer, pubmed, cell, article, atra, google, scholar, levels, aldh, fig, cas, csclike, aldhl, aldha, expression, properties, ovarian, high, stem, activation, protein, tumor, treatment, level, resistance, compared, csc, usa, breast, aldhhigh, formation, adr, experiments, central, signaling, growth, cscs, autophagy, drug, bcrp, activity, determined, acid, akrc, nature, dehydrogenase, nqo,

Topics {✒️}

nature portfolio privacy policy national research foundation balb/c-nu/nu mice advertising nature 445 nature 432 nature aldh-h-derived tumor growth opti-mem media reprints human colon-cancer-initiating cells aldh1-low doxorubicin-resistant cells aldh1a1-mediated development japan thermo fisher scientific mi-kyoung kwak aldh-h-derived tumors aldefluor-derived fluorescence intensity retinoic acid receptor-α63 beta-catenin-regulated aldh1a1 aldo-keto reductase 1c1 pan-histone deacetylase inhibitor aldehyde-dehydrogenase gene transfer pancreatic tumour-initiating cells 5 μg/μl oligo dt12–18 social media anchorage-independent growth ability aldehyde dehydrogenase 1a1 cell death dis drug-tolerant cancer cells p62-mediated autophagic degradation aldh1-mediated nrf2 activation nrf2-mediated drug resistance real-time reverse transcriptase 5 μg/ml bovine insulin stable transgene-expressing cells aldh1-mediated nrf2 upregulation cd44-high colorectal cscs inhibits tumour formation sirna-mediated p62-silencing stem/progenitor cell properties aldh1-enriched ovarian cscs bo-hyun choi nrf2-mediated stress resistance c-met/pi3k signaling aldh1-high cancer cells sphere-forming capacity compared real-time rt-pcr student−newman−keuls tests

Questions {❓}

• Oxidative stress, mammospheres and Nrf2–new implication for breast cancer therapy?
• Stem cells in cancer: instigators and propagators?
• Tackling the cancer stem cells—what challenges do they pose?

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      headline:High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling
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