
NCBI . NLM . NIH . GOV {
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Title[redir]:
Accumulation of ALDH1-positive cells after neoadjuvant chemotherapy predicts treatment resistance and prognosticates poor outcome in ovarian cancer - PMC
Description:
Although ovarian cancer is a highly chemosensitive disease, it is only infrequently cured. One of the major reasons lies in the presence of drug-resistant cancer stem-like cells, sufficient to fuel recurrence. We phenotyped cancer stem-like cells by ...
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Keywords {๐}
doi, cancer, cells, aldh, cscs, google, scholar, pubmed, ovarian, expression, tumor, pmc, chemotherapy, article, cell, free, eoc, analysis, stem, nac, disease, patients, treatment, response, data, figure, aldhhigh, staining, tumors, tissue, neoadjuvant, resistance, poor, survival, high, clinical, csc, outcome, median, marker, results, low, study, table, logfc, surgery, determined, time, found, stemlike,
Topics {โ๏ธ}
current anti-cancer agents taxane/platinum-based neoadjuvant chemotherapy pmc beta search mignon-denise keyver-paik 1 csc-focused anticancer strategies term โoptimal cytoreduction ovarian cancer-initiating cells high-expressing cancer cells post-chemotherapy ovarian carcinoma age-standardized mortality rate ascites-derived epcam+ cells advanced-stage ovarian cancer short-term single treatment drug-resistant cancer stem taxane/platinum-based chemotherapy cancer-/tumor-initiating cells cancer-supporting m2 macrophages chemotherapy-naรฏve tissue specimens supplementary materials oncotarget-06-16437-s001 aldh-positive cancer-stem recurrence-free survival taxane/platinum-treated samples csc-antigen expression levels epithelial ovarian cancer xenograft mouse model human epithelial cancers post-chemotherapeutic site relapse-free intervals [google scholar] 55 pre-chemotherapeutic tissue samples bright field image advanced ovarian cancer csc-related molecules supplementary material figures nac-treated tissue samples therapy-naรฏve eoc patients considered highly sensitive cell stem cell ovarian cancer cells ovarian cancer tiyasha cancer stem cell csc-related markers license information pmcid aldehyde dehydrogenase-1 expression primary human tumors kaplan-meier method figo stage iiic/iv iv ovarian cancer residual cancer burden cancer stem cells
Questions {โ}
- Ovarian cancer stem cells: Are they real and why are they important?
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