
NATURE . COM {
}
Title:
High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling | Cell Death & Disease
Description:
Aldehyde dehydrogenase 1A1 (ALDH1A1) is one of cancer stem cell (CSC) markers, and high ALDH1 expression has been related to drug resistance and facilitated tumor growth. In this study, we investigated the potential involvement of nuclear factor erythroid 2-like 2 (NFE2L2/NRF2) in CSC-like properties of ALDH-high ovarian CSCs. Our experimental system, ALDH1A1-high (ALDH-H) subpopulation, was isolated and stabilized using doxorubicin-resistant ovarian cancer A2780 cells. ALDH-H exerted CSC-like properties such as drug resistance, colony/sphere formation, and enhanced tumor growth along with high levels of CSCs markers compared to ALDH1A1-low (ALDH-L). Levels of NRF2 and subsequent target genes substantially increased in ALDH-H cells, and the increase in ALDH1A1 and p62 was associated with NRF2 upregulation. ALDH1A1-silencing blocked increases in NRF2, drug efflux transporters, and p62, along with CSC markers in ALDH-H cells. The inhibition of p62, which was elevated in ALDH-H, suppressed NRF2 activation. High NRF2 level was confirmed in the ALDH1-high subpopulation from colon cancer HCT116 cells. The functional implication of NRF2 activation in ovarian CSCs was verified by two experimental approaches. First, CSC-like properties such as high CSC markers, chemoresistance, colony/sphere formation, and tumor growth were significantly inhibited by NRF2-silencing in ALDH-H cells. Second, all-trans retinoic acid (ATRA) suppressed ALDH1 expression, inhibiting NRF2 activation, which led to the attenuation of CSC-like properties in ALDH-H cells but not in ALDH-L cells. These results provide insight into the molecular basis of the ALDH1A1-mediated development of CSC-like properties such as stress/treatment resistance, and further suggest the therapeutic potential of ATRA in ALDH-high ovarian CSCs.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {📚}
- Science
- Health & Fitness
- Education
Content Management System {📝}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of nature.com audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,058 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {💸}
Display Ads {🎯}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {💰}
Display Ads {🎯}
$63,100 per month
Estimations show Nature.com's display ad online revenue falls between $42,042 and $115,617 per month.
Keywords {🔍}
cells, nrf, aldhh, cancer, pubmed, cell, article, atra, google, scholar, levels, aldh, fig, cas, csclike, aldhl, aldha, expression, properties, ovarian, high, stem, activation, protein, tumor, treatment, level, resistance, compared, csc, usa, breast, aldhhigh, formation, adr, experiments, central, signaling, growth, cscs, autophagy, drug, bcrp, activity, determined, acid, akrc, nature, dehydrogenase, nqo,
Topics {✒️}
nature portfolio privacy policy national research foundation balb/c-nu/nu mice advertising nature 445 nature 432 nature aldh-h-derived tumor growth opti-mem media reprints human colon-cancer-initiating cells aldh1-low doxorubicin-resistant cells aldh1a1-mediated development japan thermo fisher scientific mi-kyoung kwak aldh-h-derived tumors aldefluor-derived fluorescence intensity retinoic acid receptor-α63 beta-catenin-regulated aldh1a1 aldo-keto reductase 1c1 pan-histone deacetylase inhibitor aldehyde-dehydrogenase gene transfer pancreatic tumour-initiating cells 5 μg/μl oligo dt12–18 social media anchorage-independent growth ability aldehyde dehydrogenase 1a1 cell death dis drug-tolerant cancer cells p62-mediated autophagic degradation aldh1-mediated nrf2 activation nrf2-mediated drug resistance real-time reverse transcriptase 5 μg/ml bovine insulin stable transgene-expressing cells aldh1-mediated nrf2 upregulation cd44-high colorectal cscs inhibits tumour formation sirna-mediated p62-silencing stem/progenitor cell properties aldh1-enriched ovarian cscs bo-hyun choi nrf2-mediated stress resistance c-met/pi3k signaling aldh1-high cancer cells sphere-forming capacity compared real-time rt-pcr student−newman−keuls tests
Questions {❓}
- Oxidative stress, mammospheres and Nrf2–new implication for breast cancer therapy?
- Stem cells in cancer: instigators and propagators?
- Tackling the cancer stem cells—what challenges do they pose?
Schema {🗺️}
WebPage:
mainEntity:
headline:High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling
description:Aldehyde dehydrogenase 1A1 (ALDH1A1) is one of cancer stem cell (CSC) markers, and high ALDH1 expression has been related to drug resistance and facilitated tumor growth. In this study, we investigated the potential involvement of nuclear factor erythroid 2-like 2 (NFE2L2/NRF2) in CSC-like properties of ALDH-high ovarian CSCs. Our experimental system, ALDH1A1-high (ALDH-H) subpopulation, was isolated and stabilized using doxorubicin-resistant ovarian cancer A2780 cells. ALDH-H exerted CSC-like properties such as drug resistance, colony/sphere formation, and enhanced tumor growth along with high levels of CSCs markers compared to ALDH1A1-low (ALDH-L). Levels of NRF2 and subsequent target genes substantially increased in ALDH-H cells, and the increase in ALDH1A1 and p62 was associated with NRF2 upregulation. ALDH1A1-silencing blocked increases in NRF2, drug efflux transporters, and p62, along with CSC markers in ALDH-H cells. The inhibition of p62, which was elevated in ALDH-H, suppressed NRF2 activation. High NRF2 level was confirmed in the ALDH1-high subpopulation from colon cancer HCT116 cells. The functional implication of NRF2 activation in ovarian CSCs was verified by two experimental approaches. First, CSC-like properties such as high CSC markers, chemoresistance, colony/sphere formation, and tumor growth were significantly inhibited by NRF2-silencing in ALDH-H cells. Second, all-trans retinoic acid (ATRA) suppressed ALDH1 expression, inhibiting NRF2 activation, which led to the attenuation of CSC-like properties in ALDH-H cells but not in ALDH-L cells. These results provide insight into the molecular basis of the ALDH1A1-mediated development of CSC-like properties such as stress/treatment resistance, and further suggest the therapeutic potential of ATRA in ALDH-high ovarian CSCs.
datePublished:2018-08-30T00:00:00Z
dateModified:2018-08-30T00:00:00Z
pageStart:1
pageEnd:17
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/s41419-018-0903-4
keywords:
Life Sciences
general
Biochemistry
Cell Biology
Immunology
Cell Culture
Antibodies
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig1_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig2_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig3_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig4_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig5_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig6_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig7_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig8_HTML.png
isPartOf:
name:Cell Death & Disease
issn:
2041-4889
volumeNumber:9
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Donghyeok Kim
affiliation:
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
type:Person
name:Bo-hyun Choi
affiliation:
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
type:Person
name:In-geun Ryoo
affiliation:
name:The Catholic University of Korea
address:
name:Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
type:Person
name:Mi-Kyoung Kwak
affiliation:
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
name:The Catholic University of Korea
address:
name:Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
name:The Catholic University of Korea
address:
name:College of Pharmacy, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling
description:Aldehyde dehydrogenase 1A1 (ALDH1A1) is one of cancer stem cell (CSC) markers, and high ALDH1 expression has been related to drug resistance and facilitated tumor growth. In this study, we investigated the potential involvement of nuclear factor erythroid 2-like 2 (NFE2L2/NRF2) in CSC-like properties of ALDH-high ovarian CSCs. Our experimental system, ALDH1A1-high (ALDH-H) subpopulation, was isolated and stabilized using doxorubicin-resistant ovarian cancer A2780 cells. ALDH-H exerted CSC-like properties such as drug resistance, colony/sphere formation, and enhanced tumor growth along with high levels of CSCs markers compared to ALDH1A1-low (ALDH-L). Levels of NRF2 and subsequent target genes substantially increased in ALDH-H cells, and the increase in ALDH1A1 and p62 was associated with NRF2 upregulation. ALDH1A1-silencing blocked increases in NRF2, drug efflux transporters, and p62, along with CSC markers in ALDH-H cells. The inhibition of p62, which was elevated in ALDH-H, suppressed NRF2 activation. High NRF2 level was confirmed in the ALDH1-high subpopulation from colon cancer HCT116 cells. The functional implication of NRF2 activation in ovarian CSCs was verified by two experimental approaches. First, CSC-like properties such as high CSC markers, chemoresistance, colony/sphere formation, and tumor growth were significantly inhibited by NRF2-silencing in ALDH-H cells. Second, all-trans retinoic acid (ATRA) suppressed ALDH1 expression, inhibiting NRF2 activation, which led to the attenuation of CSC-like properties in ALDH-H cells but not in ALDH-L cells. These results provide insight into the molecular basis of the ALDH1A1-mediated development of CSC-like properties such as stress/treatment resistance, and further suggest the therapeutic potential of ATRA in ALDH-high ovarian CSCs.
datePublished:2018-08-30T00:00:00Z
dateModified:2018-08-30T00:00:00Z
pageStart:1
pageEnd:17
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/s41419-018-0903-4
keywords:
Life Sciences
general
Biochemistry
Cell Biology
Immunology
Cell Culture
Antibodies
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig1_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig2_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig3_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig4_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig5_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig6_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig7_HTML.png
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_Fig8_HTML.png
isPartOf:
name:Cell Death & Disease
issn:
2041-4889
volumeNumber:9
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Donghyeok Kim
affiliation:
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
type:Person
name:Bo-hyun Choi
affiliation:
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
type:Person
name:In-geun Ryoo
affiliation:
name:The Catholic University of Korea
address:
name:Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
type:Person
name:Mi-Kyoung Kwak
affiliation:
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
name:The Catholic University of Korea
address:
name:Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
name:The Catholic University of Korea
address:
name:College of Pharmacy, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
["Periodical","PublicationVolume"]:
name:Cell Death & Disease
issn:
2041-4889
volumeNumber:9
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
name:The Catholic University of Korea
address:
name:Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
name:The Catholic University of Korea
address:
name:Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
name:The Catholic University of Korea
address:
name:College of Pharmacy, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Donghyeok Kim
affiliation:
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
name:Bo-hyun Choi
affiliation:
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
name:In-geun Ryoo
affiliation:
name:The Catholic University of Korea
address:
name:Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
name:Mi-Kyoung Kwak
affiliation:
name:Graduate School of the Catholic University of Korea
address:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
name:The Catholic University of Korea
address:
name:Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
name:The Catholic University of Korea
address:
name:College of Pharmacy, The Catholic University of Korea, Bucheon, Republic of Korea
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
name:Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, Republic of Korea
name:Department of Pharmacy, Graduate School of the Catholic University of Korea, Bucheon, Republic of Korea
name:Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, Republic of Korea
name:College of Pharmacy, The Catholic University of Korea, Bucheon, Republic of Korea
External Links {🔗}(226)
- What's the income of https://doi.org/10.1038%2Fnrd4253?
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24981363 generate?
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234172?
- How much does http://scholar.google.com/scholar_lookup?&title=Tackling%20the%20cancer%20stem%20cells%E2%80%94what%20challenges%20do%20they%20pose%3F&journal=Nat.%20Rev.%20Drug%20Discov.&doi=10.1038%2Fnrd4253&volume=13&pages=497-512&publication_year=2014&author=Pattabiraman%2CDR&author=Weinberg%2CRA generate monthly?
- How much does https://doi.org/10.1073%2Fpnas.0530291100 rake in every month?
- What's the financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12629218?
- How much revenue does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153034 produce monthly?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Prospective%20identification%20of%20tumorigenic%20breast%20cancer%20cells&journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0530291100&volume=100&pages=3983-3988&publication_year=2003&author=Al-Hajj%2CM&author=Wicha%2CMS&author=Benito-Hernandez%2CA&author=Morrison%2CSJ&author=Clarke%2CMF each month?
- What's the financial gain of https://doi.org/10.1038%2Fnm0797-730?
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9212098 generate?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Human%20acute%20myeloid%20leukemia%20is%20organized%20as%20a%20hierarchy%20that%20originates%20from%20a%20primitive%20hematopoietic%20cell&journal=Nat.%20Med.&doi=10.1038%2Fnm0797-730&volume=3&pages=730-737&publication_year=1997&author=Bonnet%2CD&author=Dick%2CJE make?
- How much does https://doi.org/10.1038%2Fnature05384 generate monthly?
- Profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17122771
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Identification%20and%20expansion%20of%20human%20colon-cancer-initiating%20cells&journal=Nature&doi=10.1038%2Fnature05384&volume=445&pages=111-115&publication_year=2007&author=Ricci-Vitiani%2CL generate?
- What's the monthly income of https://doi.org/10.1038%2Fnature03128?
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15549107
- http://scholar.google.com/scholar_lookup?&title=Identification%20of%20human%20brain%20tumour%20initiating%20cells&journal=Nature&doi=10.1038%2Fnature03128&volume=432&pages=396-401&publication_year=2004&author=Singh%2CSK income
- Profit of https://doi.org/10.1242%2Fjcs.054296
- What's the financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20592182?
- How much income does http://scholar.google.com/scholar_lookup?&title=Stem%20cells%20in%20cancer%3A%20instigators%20and%20propagators%3F&journal=J.%20Cell%20Sci.&doi=10.1242%2Fjcs.054296&volume=123&pages=2357-2368&publication_year=2010&author=Alison%2CMR&author=Islam%2CS&author=Wright%2CNA have?
- What's the income of https://doi.org/10.1172%2FJCI41004?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20051635 rake in every month?
- Find out how much http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798700 earns monthly
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=The%20therapeutic%20promise%20of%20the%20cancer%20stem%20cell%20concept&journal=J.%20Clin.%20Invest.&doi=10.1172%2FJCI41004&volume=120&pages=41-50&publication_year=2010&author=Frank%2CNY&author=Schatton%2CT&author=Frank%2CMH?
- https://doi.org/10.1155%2F2016%2F2428153's financial summary
- How much cash flow does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26682001 have monthly?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Redox%20modulating%20NRF2%3A%20a%20potential%20mediator%20of%20cancer%20stem%20cell%20resistance&journal=Oxid.%20Med.%20Cell.%20Longev.&doi=10.1155%2F2016%2F2428153&volume=2016&publication_year=2016&author=Ryoo%2CIG&author=Lee%2CSH&author=Kwak%2CMK each month?
- How much revenue does https://doi.org/10.1073%2Fpnas.0905653106 generate?
- What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19805294?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741477 bring in each month?
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Highly%20tumorigenic%20lung%20cancer%20CD133%2B%20cells%20display%20stem-like%20features%20and%20are%20spared%20by%20cisplatin%20treatment&journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0905653106&volume=106&pages=16281-16286&publication_year=2009&author=Bertolini%2CG?
- How much revenue does https://doi.org/10.1158%2F0008-5472.CAN-05-0626 generate?
- What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15994920?
- http://scholar.google.com/scholar_lookup?&title=Isolation%20and%20in%20vitro%20propagation%20of%20tumorigenic%20breast%20cancer%20cells%20with%20stem%2Fprogenitor%20cell%20properties&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-05-0626&volume=65&pages=5506-5511&publication_year=2005&author=Ponti%2CD income
- Profit of https://doi.org/10.1634%2Fstemcells.2004-0170
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15579635's revenue stream
- How much profit does http://scholar.google.com/scholar_lookup?&title=Phenotypic%20characterization%20of%20murine%20primitive%20hematopoietic%20progenitor%20cells%20isolated%20on%20basis%20of%20aldehyde%20dehydrogenase%20activity&journal=Stem%20Cells&doi=10.1634%2Fstemcells.2004-0170&volume=22&pages=1142-1151&publication_year=2004&author=Armstrong%2CL generate?
- How much profit is https://doi.org/10.1158%2F1541-7786.MCR-08-0393 making per month?
- What's the financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19276181?
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255559?
- What's http://scholar.google.com/scholar_lookup?&title=Aldehyde%20dehydrogenase%201%20is%20a%20tumor%20stem%20cell-associated%20marker%20in%20lung%20cancer&journal=Mol.%20Cancer%20Res.&doi=10.1158%2F1541-7786.MCR-08-0393&volume=7&pages=330-338&publication_year=2009&author=Jiang%2CF's gross income?
- What's the total monthly financial gain of https://doi.org/10.1158%2F0008-5472.CAN-09-3806?
- What's the income generated by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20516116 each month?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=High%20aldehyde%20dehydrogenase%20activity%20identifies%20tumor-initiating%20and%20metastasis-initiating%20cells%20in%20human%20prostate%20cancer&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-09-3806&volume=70&pages=5163-5173&publication_year=2010&author=Hoogen%2CC produce monthly?
- How much money does https://doi.org/10.1016%2Fj.stem.2007.08.014 generate?
- Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18371393
- Get to know http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423808's earnings
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=ALDH1%20is%20a%20marker%20of%20normal%20and%20malignant%20human%20mammary%20stem%20cells%20and%20a%20predictor%20of%20poor%20clinical%20outcome&journal=Cell%20Stem%20Cell&doi=10.1016%2Fj.stem.2007.08.014&volume=1&pages=555-567&publication_year=2007&author=Ginestier%2CC?
- How much does https://doi.org/10.1158%2F1078-0432.CCR-12-2857 bring in each month?
- Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23969936
- What's http://scholar.google.com/scholar_lookup?&title=Characterization%20and%20clinical%20relevance%20of%20ALDHbright%20populations%20in%20prostate%20cancer&journal=Clin.%20Cancer%20Res.&doi=10.1158%2F1078-0432.CCR-12-2857&volume=19&pages=5361-5371&publication_year=2013&author=Magnen%2CC's gross income?
- What is the monthly revenue of https://doi.org/10.1371%2Fjournal.pone.0081050?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24282568 produce monthly?
- What are the total earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839885?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Prognostic%20value%20of%20cancer%20stem%20cell%20marker%20aldehyde%20dehydrogenase%20in%20ovarian%20cancer%3A%20a%20meta-analysis&journal=PLoS%20ONE&doi=10.1371%2Fjournal.pone.0081050&volume=8&publication_year=2013&author=Liu%2CS each month?
- https://doi.org/10.18632%2Foncotarget.4103's total income per month
- See how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25999351 makes per month
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599280 rake in every month?
- How much does http://scholar.google.com/scholar_lookup?&title=Accumulation%20of%20ALDH1-positive%20cells%20after%20neoadjuvant%20chemotherapy%20predicts%20treatment%20resistance%20and%20prognosticates%20poor%20outcome%20in%20ovarian%20cancer&journal=Oncotarget&doi=10.18632%2Foncotarget.4103&volume=6&pages=16437-16448&publication_year=2015&author=Ayub%2CTH earn?
- How much does https://doi.org/10.1038%2Fonc.2014.178 bring in each month?
- What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24954508?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=beta-Catenin-regulated%20ALDH1A1%20is%20a%20target%20in%20ovarian%20cancer%20spheroids&journal=Oncogene&doi=10.1038%2Fonc.2014.178&volume=34&pages=2297-2308&publication_year=2015&author=Condello%2CS is on a monthly basis
- https://doi.org/10.1002%2Fmc.22526's revenue stream
- How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=27380877?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Cancer%20stem%20cell%20mediated%20acquired%20chemoresistance%20in%20head%20and%20neck%20cancer%20can%20be%20abrogated%20by%20aldehyde%20dehydrogenase%201%20A1%20inhibition&journal=Mol.%20Carcinog.&doi=10.1002%2Fmc.22526&volume=56&pages=694-711&publication_year=2017&author=Kulsum%2CS make?
- How much revenue does https://doi.org/10.1016%2Fj.biocel.2016.07.017 generate?
- What are the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=27443528?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20ALDH1A1%20activity%20decreases%20expression%20of%20drug%20transporters%20and%20reduces%20chemotherapy%20resistance%20in%20ovarian%20cancer%20cell%20lines&journal=Int.%20J.%20Biochem.%20Cell%20Biol.&doi=10.1016%2Fj.biocel.2016.07.017&volume=78&pages=248-259&publication_year=2016&author=Januchowski%2CR bring in?
- What's the monthly money flow for https://doi.org/10.4161%2Fcbt.215?
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14508093
- http://scholar.google.com/scholar_lookup?&title=Retinoid%20targets%20in%20cancer%20therapy%20and%20chemoprevention&journal=Cancer%20Biol.%20Ther.&doi=10.4161%2Fcbt.215&volume=2&pages=S150-S156&publication_year=2003&author=Dragnev%2CKH&author=Petty%2CWJ&author=Dmitrovsky%2CE's total income per month
- What's the profit of https://doi.org/10.1056%2FNEJM199710093371501?
- What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9321529?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=All-trans-retinoic%20acid%20in%20acute%20promyelocytic%20leukemia&journal=N.%20Engl.%20J.%20Med.&doi=10.1056%2FNEJM199710093371501&volume=337&pages=1021-1028&publication_year=1997&author=Tallman%2CMS?
- https://doi.org/10.1038%2Fonc.2011.58's financial summary
- What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21383690?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955956 rake in every month?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20glioblastoma%20stem%20cells%20by%20retinoic%20acid%3A%20role%20for%20Notch%20pathway%20inhibition&journal=Oncogene&doi=10.1038%2Fonc.2011.58&volume=30&pages=3454-3467&publication_year=2011&author=Ying%2CM is on a monthly basis
- How much does https://doi.org/10.1124%2Fjpet.104.072496 pull in monthly?
- How much income does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15470086 have?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Retinoic%20acid%20down-regulates%20aldehyde%20dehydrogenase%20and%20increases%20cytotoxicity%20of%204-hydroperoxycyclophosphamide%20and%20acetaldehyde&journal=J.%20Pharmacol.%20Exp.%20Ther.&doi=10.1124%2Fjpet.104.072496&volume=312&pages=339-345&publication_year=2005&author=Moreb%2CJS
- https://doi.org/10.1016%2Fj.ygyno.2011.12.425's revenue stream
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22155260 bring in each month?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=The%20impact%20of%20novel%20retinoids%20in%20combination%20with%20platinum%20chemotherapy%20on%20ovarian%20cancer%20stem%20cells&journal=Gynecol.%20Oncol.&doi=10.1016%2Fj.ygyno.2011.12.425&volume=125&pages=226-230&publication_year=2012&author=Whitworth%2CJM?
- Discover the revenue of https://doi.org/10.1016%2Fj.tibs.2008.12.008
- How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19321346?
- How much profit does http://scholar.google.com/scholar_lookup?&title=NRF2%20and%20KEAP1%20mutations%3A%20permanent%20activation%20of%20an%20adaptive%20response%20in%20cancer&journal=Trends%20Biochem.%20Sci.&doi=10.1016%2Fj.tibs.2008.12.008&volume=34&pages=176-188&publication_year=2009&author=Hayes%2CJD&author=McMahon%2CM generate?
- Find out how much https://doi.org/10.1006%2Fbbrc.1997.6943 earns monthly
- How much cash flow does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9240432 have monthly?
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=An%20Nrf2%2Fsmall%20Maf%20heterodimer%20mediates%20the%20induction%20of%20phase%20II%20detoxifying%20enzyme%20genes%20through%20antioxidant%20response%20elements&journal=Biochem.%20Biophys.%20Res.%20Commun.&doi=10.1006%2Fbbrc.1997.6943&volume=236&pages=313-322&publication_year=1997&author=Itoh%2CK?
- How much does https://doi.org/10.1128%2FMCB.00248-10 net monthly?
- What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20421418?
- Profit of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897585
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=A%20noncanonical%20mechanism%20of%20Nrf2%20activation%20by%20autophagy%20deficiency%3A%20direct%20interaction%20between%20Keap1%20and%20p62&journal=Mol.%20Cell.%20Biol.&doi=10.1128%2FMCB.00248-10&volume=30&pages=3275-3285&publication_year=2010&author=Lau%2CA?
- What's the income of https://doi.org/10.1038%2Fncb2021?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20173742 income
- How much does http://scholar.google.com/scholar_lookup?&title=The%20selective%20autophagy%20substrate%20p62%20activates%20the%20stress%20responsive%20transcription%20factor%20Nrf2%20through%20inactivation%20of%20Keap1&journal=Nat.%20Cell%20Biol.&doi=10.1038%2Fncb2021&volume=12&pages=213-223&publication_year=2010&author=Komatsu%2CM pull in monthly?
- How much revenue does https://doi.org/10.1101%2Fgad.225680.113 generate?
- How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24142871 making per month?
- What's the income of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814639?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=The%20emerging%20role%20of%20the%20Nrf2-Keap1%20signaling%20pathway%20in%20cancer&journal=Genes%20Dev.&doi=10.1101%2Fgad.225680.113&volume=27&pages=2179-2191&publication_year=2013&author=Jaramillo%2CMC&author=Zhang%2CDD
- How much does https://link.springer.com/doi/10.1186/1471-2407-13-380 pull in monthly?
- How much income does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23937621 have?
- What's the financial gain of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751732?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Nrf2%20is%20required%20to%20maintain%20the%20self-renewal%20of%20glioma%20stem%20cells&journal=Bmc%20Cancer&doi=10.1186%2F1471-2407-13-380&volume=13&publication_year=2013&author=Zhu%2CJ
- What is the earnings of https://doi.org/10.18632%2Foncotarget.3047?
- See how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25717032 makes per month
- How much money does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480743 make?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Activation%20of%20NRF2%20by%20p62%20and%20proteasome%20reduction%20in%20sphere-forming%20breast%20carcinoma%20cells&journal=Oncotarget&doi=10.18632%2Foncotarget.3047&volume=6&pages=8167-8184&publication_year=2015&author=Ryoo%2CIG&author=Choi%2CBH&author=Kwak%2CMK make?
- What are the total earnings of https://doi.org/10.4062%2Fbiomolther.2016.145?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Involvement%20of%20NRF2%20signaling%20in%20doxorubicin%20resistance%20of%20cancer%20stem%20cell-enriched%20colonospheres&journal=Biomol.%20Ther.&doi=10.4062%2Fbiomolther.2016.145&volume=24&publication_year=2016&author=Ryoo%2CIg&author=Kim%2CG&author=Choi%2CBh&author=Lee%2CSh&author=Kwak%2CMK
- Revenue of https://doi.org/10.1016%2Fj.freeradbiomed.2009.09.006
- Financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19751820
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Acquisition%20of%20doxorubicin%20resistance%20in%20ovarian%20carcinoma%20cells%20accompanies%20activation%20of%20the%20NRF2%20pathway&journal=Free%20Radic.%20Biol.%20Med.&doi=10.1016%2Fj.freeradbiomed.2009.09.006&volume=47&pages=1619-1631&publication_year=2009&author=Shim%2CGS&author=Manandhar%2CS&author=Shin%2CDH&author=Kim%2CTH&author=Kwak%2CMK?
- How much revenue does https://doi.org/10.1124%2Fmol.114.096065 produce monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25534417 rake in every month?
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=The%20c-MET%2FPI3K%20signaling%20is%20associated%20with%20cancer%20resistance%20to%20doxorubicin%20and%20photodynamic%20therapy%20by%20elevating%20BCRP%2FABCG2%20expression&journal=Mol.%20Pharmacol.&doi=10.1124%2Fmol.114.096065&volume=87&pages=465-476&publication_year=2015&author=Jung%2CKA&author=Choi%2CBH&author=Kwak%2CMK?
- What's the financial gain of https://doi.org/10.1016%2Fj.cmet.2012.12.002?
- How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23274085 making per month?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Sestrins%20activate%20Nrf2%20by%20promoting%20p62-dependent%20autophagic%20degradation%20of%20Keap1%20and%20prevent%20oxidative%20liver%20damage&journal=Cell%20Metab.&doi=10.1016%2Fj.cmet.2012.12.002&volume=17&pages=73-84&publication_year=2013&author=Bae%2CSH?
- How much revenue does https://doi.org/10.1158%2F0008-5472.CAN-06-1690 bring in?
- How much cash flow does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16982775 have monthly?
- Discover the revenue of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1586106
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=All-trans-retinoic%20acid%20improves%20differentiation%20of%20myeloid%20cells%20and%20immune%20response%20in%20cancer%20patients&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-06-1690&volume=66&pages=9299-9307&publication_year=2006&author=Mirza%2CN?
- Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9426070
- How much income does http://scholar.google.com/scholar_lookup?&title=Retinoic%20acid%20receptor%20beta%20induces%20terminal%20differentiation%20of%20squamous%20cell%20carcinoma%20lines%20in%20the%20absence%20of%20cyclin-dependent%20kinase%20inhibitor%20expression&journal=Cancer%20Res.&volume=58&pages=142-148&publication_year=1998&author=Crowe%2CDL have?
- What's the profit of https://doi.org/10.1158%2F1535-7163.MCT-10-0563?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20889728 net monthly?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005138 generate monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Targeting%20aldehyde%20dehydrogenase%20cancer%20stem%20cells%20in%20ovarian%20cancer&journal=Mol.%20Cancer%20Ther.&doi=10.1158%2F1535-7163.MCT-10-0563&volume=9&pages=3186-3199&publication_year=2010&author=Landen%2CCN rake in every month?
- Income figures for https://doi.org/10.3892%2Fijo.2012.1516
- How much cash flow does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22710732 have monthly?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508685 pull in?
- How much does http://scholar.google.com/scholar_lookup?&title=Aldehyde%20dehydrogenase%201A1%20confers%20intrinsic%20and%20acquired%20resistance%20to%20gemcitabine%20in%20human%20pancreatic%20adenocarcinoma%20MIA%20PaCa-2%20cells&journal=Int.%20J.%20Oncol.&doi=10.3892%2Fijo.2012.1516&volume=41&pages=855-861&publication_year=2012&author=Duong%2CHQ earn?
- How much revenue does https://doi.org/10.1158%2F0008-5472.CAN-13-3456 generate?
- What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24812274's gross income?
- How much does http://scholar.google.com/scholar_lookup?&title=The%20cancer%20stem%20cell%20marker%20aldehyde%20dehydrogenase%20is%20required%20to%20maintain%20a%20drug-tolerant%20tumor%20cell%20subpopulation&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-13-3456&volume=74&pages=3579-3590&publication_year=2014&author=Raha%2CD pull in monthly?
- Find out how much https://doi.org/10.1038%2Fmodpathol.2009.35 earns monthly
- What's the monthly money flow for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19329942?
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692456's financial summary
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=ALDH1%20expression%20correlates%20with%20favorable%20prognosis%20in%20ovarian%20cancers&journal=Mod.%20Pathol.&doi=10.1038%2Fmodpathol.2009.35&volume=22&pages=817-823&publication_year=2009&author=Chang%2CB is on a monthly basis
- Financial intake of https://doi.org/10.1016%2Fj.humpath.2017.06.025
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=28851663 rake in every month?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Aldehyde%20dehydrogenase%201A1%20%28ALDH1A1%29%20expression%20by%20immunohistochemistry%20is%20associated%20with%20chemo-refractoriness%20in%20patients%20with%20high-grade%20ovarian%20serous%20carcinoma&journal=Hum.%20Pathol.&doi=10.1016%2Fj.humpath.2017.06.025&volume=73&pages=1-6&publication_year=2018&author=Roy%2CM&author=Connor%2CJ&author=Al-Niaimi%2CA&author=Rose%2CSL&author=Mahajan%2CA is on a monthly basis
- How much income is https://doi.org/10.1016%2Fj.ajpath.2011.11.015 earning monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22222226 generate monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=ALDH1-bright%20epithelial%20ovarian%20cancer%20cells%20are%20associated%20with%20CD44%20expression%2C%20drug%20resistance%2C%20and%20poor%20clinical%20outcome&journal=Am.%20J.%20Pathol.&doi=10.1016%2Fj.ajpath.2011.11.015&volume=180&pages=1159-1169&publication_year=2012&author=Wang%2CYC rake in every month?
- Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8562935
- How much does http://scholar.google.com/scholar_lookup?&title=Induction%20of%20cyclophosphamide-resistance%20by%20aldehyde-dehydrogenase%20gene%20transfer&journal=Blood&volume=87&pages=1097-1103&publication_year=1996&author=Magni%2CM pull in?
- How much does https://doi.org/10.1016%2Fj.freeradbiomed.2012.11.010 earn?
- Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23195683 is on a monthly basis
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Aldehyde%20dehydrogenases%20in%20cellular%20responses%20to%20oxidative%2Felectrophilic%20stress&journal=Free%20Radic.%20Biol.%20Med.&doi=10.1016%2Fj.freeradbiomed.2012.11.010&volume=56&pages=89-101&publication_year=2013&author=Singh%2CS?
- What's the financial outcome of https://doi.org/10.1016%2Fj.semcancer.2014.06.004?
- What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24956577?
- How much does http://scholar.google.com/scholar_lookup?&title=A%20role%20for%20cancer%20stem%20cells%20in%20therapy%20resistance%3A%20cellular%20and%20molecular%20mechanisms&journal=Semin.%20Cancer%20Biol.&doi=10.1016%2Fj.semcancer.2014.06.004&volume=31&pages=16-27&publication_year=2015&author=Cojoc%2CM&author=Mabert%2CK&author=Muders%2CMH&author=Dubrovska%2CA pull in monthly?
- How much does https://doi.org/10.1074%2Fjbc.M110.200675 generate monthly?
- What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21878644?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199523 net monthly?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Drug-induced%20senescence%20generates%20chemoresistant%20stemlike%20cells%20with%20low%20reactive%20oxygen%20species&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M110.200675&volume=286&pages=37813-37829&publication_year=2011&author=Achuthan%2CS&author=Santhoshkumar%2CTR&author=Prabhakar%2CJ&author=Nair%2CSA&author=Pillai%2CMR
- How much revenue does https://doi.org/10.1016%2Fj.jprot.2013.06.027 produce monthly?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=The%20secretome%20of%20colon%20cancer%20stem%20cells%20contains%20drug-metabolizing%20enzymes&journal=J.%20Proteom.&doi=10.1016%2Fj.jprot.2013.06.027&volume=91&pages=84-96&publication_year=2013&author=Emmink%2CBL?
- Profit of https://doi.org/10.1002%2Fmc.22202
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Oxidative%20stress%2C%20mammospheres%20and%20Nrf2%E2%80%93new%20implication%20for%20breast%20cancer%20therapy%3F&journal=Mol.%20Carcino.&doi=10.1002%2Fmc.22202&volume=54&pages=1494-1502&publication_year=2015&author=Wu%2CT&author=Harder%2CBG&author=Wong%2CPK&author=Lang%2CJE&author=Zhang%2CDD generate?
- How much does https://doi.org/10.1016%2Fj.redox.2018.04.015 pull in?
- What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=29729523?
- Revenue of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006726
- How much revenue does http://scholar.google.com/scholar_lookup?&title=High%20CD44%20expression%20mediates%20p62-associated%20NFE2L2%2FNRF2%20activation%20in%20breast%20cancer%20stem%20cell-like%20cells%3A%20implications%20for%20cancer%20stem%20cell%20resistance&journal=Redox%20Biol.&doi=10.1016%2Fj.redox.2018.04.015&volume=17&pages=246-258&publication_year=2018&author=Ryoo%2CIG&author=Choi%2CBH&author=Ku%2CSK&author=Kwak%2CMK produce monthly?
- Income figures for https://doi.org/10.1038%2Fonc.2012.111
- Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22525272
- http://scholar.google.com/scholar_lookup?&title=The%20autophagy-associated%20factors%20DRAM1%20and%20p62%20regulate%20cell%20migration%20and%20invasion%20in%20glioblastoma%20stem%20cells&journal=Oncogene&doi=10.1038%2Fonc.2012.111&volume=32&pages=699-712&publication_year=2013&author=Galavotti%2CS income
- https://doi.org/10.1038%2Fonc.2016.202's total income per month
- Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=27345399
- How much profit is http://scholar.google.com/scholar_lookup?&title=p62%2FSQSTM1%20enhances%20breast%20cancer%20stem-like%20properties%20by%20stabilizing%20MYC%20mRNA&journal=Oncogene&doi=10.1038%2Fonc.2016.202&volume=36&pages=304-317&publication_year=2017&author=Xu%2CL making per month?
- What's https://doi.org/10.1016%2Fj.ccell.2016.04.006's gross income?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=27211490 bring in?
- Get to know http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907799's earnings
- How much does http://scholar.google.com/scholar_lookup?&title=p62%2C%20Upregulated%20during%20preneoplasia%2C%20induces%20hepatocellular%20carcinogenesis%20by%20maintaining%20survival%20of%20stressed%20HCC-initiating%20cells&journal=Cancer%20Cell&doi=10.1016%2Fj.ccell.2016.04.006&volume=29&pages=935-948&publication_year=2016&author=Umemura%2CA pull in?
- Learn about the earnings of https://doi.org/10.4161%2Fauto.24132
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23486312 bring in each month?
- What's http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672294's gross income?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Autophagy%20in%20stem%20cells&journal=Autophagy&doi=10.4161%2Fauto.24132&volume=9&pages=830-849&publication_year=2013&author=Guan%2CJL?
- How much money does https://doi.org/10.1038%2Fonc.2012.252 make?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22733132 bring in?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Beclin%201%20and%20autophagy%20are%20required%20for%20the%20tumorigenicity%20of%20breast%20cancer%20stem-like%2Fprogenitor%20cells&journal=Oncogene&doi=10.1038%2Fonc.2012.252&volume=32&pages=2261-2272&publication_year=2013&author=Gong%2CC
- What's the financial gain of https://doi.org/10.1016%2Fj.bbrc.2013.04.053?
- Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23624503 is on a monthly basis
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Autophagy%20of%20cancer%20stem%20cells%20is%20involved%20with%20chemoresistance%20of%20colon%20cancer%20cells&journal=Biochem.%20Biophys.%20Res.%20Commun.&doi=10.1016%2Fj.bbrc.2013.04.053&volume=434&pages=898-903&publication_year=2013&author=Wu%2CS&author=Wang%2CX&author=Chen%2CJ&author=Chen%2CY?
- What is the monthly revenue of https://doi.org/10.1158%2F1535-7163.MCT-11-0979?
- What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22367781?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Combination%20of%20pan-histone%20deacetylase%20inhibitor%20and%20autophagy%20inhibitor%20exerts%20superior%20efficacy%20against%20triple-negative%20human%20breast%20cancer%20cells&journal=Mol.%20Cancer%20Ther.&doi=10.1158%2F1535-7163.MCT-11-0979&volume=11&pages=973-983&publication_year=2012&author=Rao%2CR
- How much does https://doi.org/10.1002%2Fpath.3994 generate monthly?
- What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22262369?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Autophagy%20mediates%20survival%20of%20pancreatic%20tumour-initiating%20cells%20in%20a%20hypoxic%20microenvironment&journal=J.%20Pathol.&doi=10.1002%2Fpath.3994&volume=227&pages=325-335&publication_year=2012&author=Rausch%2CV?
- Discover the revenue of https://link.springer.com/doi/10.1007/s00280-016-3213-5
- What is the monthly revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=27942929?
- How much income is http://scholar.google.com/scholar_lookup?&title=Use%20of%20retinoic%20acid%2Faldehyde%20dehydrogenase%20pathway%20as%20potential%20targeted%20therapy%20against%20cancer%20stem%20cells&journal=Cancer%20Chemother.%20Pharmacol.&doi=10.1007%2Fs00280-016-3213-5&volume=79&pages=295-301&publication_year=2017&author=Moreb%2CJS&author=Ucar-Bilyeu%2CDA&author=Khan%2CA earning monthly?
- How much profit does https://doi.org/10.1093%2Fcarcin%2Fbgv018 make?
- Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25742746
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=All-trans%20retinoic%20acid%20downregulates%20ALDH1-mediated%20stemness%20and%20inhibits%20tumour%20formation%20in%20ovarian%20cancer%20cells&journal=Carcinogenesis&doi=10.1093%2Fcarcin%2Fbgv018&volume=36&pages=498-507&publication_year=2015&author=Young%2CMJ?
- How much profit does https://doi.org/10.1073%2Fpnas.0709483104 make?
- Discover the revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18048326
- Revenue of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148333
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Identification%20of%20retinoic%20acid%20as%20an%20inhibitor%20of%20transcription%20factor%20Nrf2%20through%20activation%20of%20retinoic%20acid%20receptor%20alpha&journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0709483104&volume=104&pages=19589-19594&publication_year=2007&author=Wang%2CXJ&author=Hayes%2CJD&author=Henderson%2CCJ&author=Wolf%2CCR?
- https://citation-needed.springer.com/v2/references/10.1038/s41419-018-0903-4?format=refman&flavour=references's financial summary
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Donghyeok%20Kim bring in each month?
- Get to know https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Donghyeok%20Kim%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's earnings
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Bo-hyun%20Choi bring in each month?
- How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Bo-hyun%20Choi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=In-geun%20Ryoo make?
- See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22In-geun%20Ryoo%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
- How much income does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mi-Kyoung%20Kwak have?
- What's the financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mi-Kyoung%20Kwak%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much cash flow does https://static-content.springer.com/esm/art%3A10.1038%2Fs41419-018-0903-4/MediaObjects/41419_2018_903_MOESM1_ESM.docx have monthly?
- How much does http://creativecommons.org/licenses/by/4.0/ generate monthly?
- How much does https://s100.copyright.com/AppDispatchServlet?title=High%20NRF2%20level%20mediates%20cancer%20stem%20cell-like%20properties%20of%20aldehyde%20dehydrogenase%C2%A0%28ALDH%29-high%20ovarian%20cancer%20cells%3A%20inhibitory%20role%20of%20all-trans%20retinoic%20acid%20in%20ALDH%2FNRF2%20signaling&author=Donghyeok%20Kim%20et%20al&contentID=10.1038%2Fs41419-018-0903-4©right=The%20Author%28s%29&publication=2041-4889&publicationDate=2018-08-30&publisherName=SpringerNature&orderBeanReset=true&oa=CC%20BY bring in each month?
- Learn how profitable https://crossmark.crossref.org/dialog/?doi=10.1038/s41419-018-0903-4 is on a monthly basis
- What's the profit of https://citation-needed.springer.com/v2/references/10.1038/s41419-018-0903-4?format=refman&flavour=citation?
- How much money does https://doi.org/10.1038/s12276-024-01180-8 make?
- How much income does https://doi.org/10.1038/s41392-024-01851-y have?
- What's the financial gain of https://doi.org/10.1038/s41419-024-06667-w?
- What's the revenue for https://doi.org/10.1007/s12013-024-01385-8?
- What's the financial gain of https://doi.org/10.1186/s13287-023-03244-4?
- How much money does https://www.protocols.io/ generate?
- Profit of https://www.natureindex.com/
- How much income is http://www.naturechina.com earning monthly?
- How much does https://www.natureasia.com/ja-jp rake in every month?
Analytics and Tracking {📊}
- Google Tag Manager
Libraries {📚}
- Prism.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {📦}
- Crossref