NATURE . COM {}

Matching Content Categories {📚}

• Education
• Health & Fitness
• Telecommunications

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$63,100 per month
Our estimates place Nature.com's monthly online earnings from display ads at $42,042 to $115,616.

Keywords {🔍}

article, pubmed, cas, google, scholar, cancer, akt, pin, nature, protein, kinase, cell, isomerase, phosphorylation, zhou, access, oncogene, breast, central, stability, human, mol, university, regulation, department, content, activation, liao, usa, center, supplementary, cookies, information, yang, chen, hung, expression, prolyl, tsichlis, privacy, peptidylprolyl, cistrans, pkbakt, role, multiple, open, signalling, targeting, biochem, sci,

Topics {✒️}

nature portfolio research development award permissions reprints privacy policy inhibit cancer-driving pathways author information authors editing mmtv-polyoma middle advertising nature 448 nature 419 nature language improvement social media phosphatidylinositol 3-kinase/akt-dependent pathway scientific publication china medical university akt-ps473 status combined prolyl isomerase pin1 serine/threonine protein kinase phosphorylated thr-pro motifs epigallocatechin-3-gallate induces apoptosis personal data springerlink instant access d3 phosphoinositide-regulated kinases dr lu kp data protection akt/pkb ser473 phosphorylation permissions multiple cancer types china akt-mtor signalling axis multiple-step process pin1 mef cells modeling breast cancer suppresses tumor growth arsenic targets pin1 alessi dr human breast cancer breast cancer patients homologue pin1 knockout testa jr privacy supplementary figure s2 supplementary figure s3 prolyl isomerase repressing pin1 expression phosphoinositide-dependent phosphorylation akt protein stability forkhead transcription factors

Questions {❓}

• Targeting carcinogenesis: a role for the prolyl isomerase Pin1?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation
         description:The serine/threonine protein kinase B (PKB, also known as Akt) plays a pivotal role in diverse cellular functions. Elevated expression of activated Akt has been detected in a wide variety of human cancers; however, the mechanism of Akt protein stability regulation remains unclear. In this study, we showed a strong correlation between the expression levels of an oncogenic peptidyl-prolyl cis/trans isomerase Pin1 and levels of Akt phosphorylation at S473 in multiple cancer types (P<0.0001). Akt-pS473 status combined with Pin1 expression levels predicted a poorer prognosis than did either one alone in patients with breast cancer (P=0.0052). We further showed that Pin1 regulated Akt stability and phosphorylation on S473 through the phosphorylated Thr-Pro motifs of Akt. These motifs are conserved evolutionary and are required for the maintenance of Akt stability and its interaction with Pin1. In addition, repressing Pin1 expression through either homologue Pin1 knockout or small interfering RNA-mediated knockingdown compromised its ability to protect Akt from degradation. Our results show how Akt protein stability is regulated by the peptidyl-prolyl cis/trans isomerase Pin1 and highlight the importance of this oncogenic network in human disease pathogenesis.
         datePublished:2009-05-18T00:00:00Z
         dateModified:2009-05-18T00:00:00Z
         pageStart:2436
         pageEnd:2445
         sameAs:https://doi.org/10.1038/onc.2009.98
         keywords:
            PKB/Akt
            Pin1
            peptidyl-prolyl cis/trans isomerase
            breast cancer
            Medicine/Public Health
            general
            Internal Medicine
            Cell Biology
            Human Genetics
            Oncology
            Apoptosis
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig5_HTML.jpg
         isPartOf:
            name:Oncogene
            issn:
               1476-5594
               0950-9232
            volumeNumber:28
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Y Liao
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Y Wei
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:X Zhou
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
                     name:Cancer Hospital, Fudan University
                     address:
                        name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:J -Y Yang
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:C Dai
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Y -J Chen
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
                     name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
                     address:
                        name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:N K Agarwal
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:D Sarbassov
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:D Shi
               affiliation:
                     name:Cancer Hospital, Fudan University
                     address:
                        name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:D Yu
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:M -C Hung
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
                     name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
                     address:
                        name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
                        type:PostalAddress
                     type:Organization
                     name:Asia University
                     address:
                        name:Asia University, Taichung, Taiwan
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation
      description:The serine/threonine protein kinase B (PKB, also known as Akt) plays a pivotal role in diverse cellular functions. Elevated expression of activated Akt has been detected in a wide variety of human cancers; however, the mechanism of Akt protein stability regulation remains unclear. In this study, we showed a strong correlation between the expression levels of an oncogenic peptidyl-prolyl cis/trans isomerase Pin1 and levels of Akt phosphorylation at S473 in multiple cancer types (P<0.0001). Akt-pS473 status combined with Pin1 expression levels predicted a poorer prognosis than did either one alone in patients with breast cancer (P=0.0052). We further showed that Pin1 regulated Akt stability and phosphorylation on S473 through the phosphorylated Thr-Pro motifs of Akt. These motifs are conserved evolutionary and are required for the maintenance of Akt stability and its interaction with Pin1. In addition, repressing Pin1 expression through either homologue Pin1 knockout or small interfering RNA-mediated knockingdown compromised its ability to protect Akt from degradation. Our results show how Akt protein stability is regulated by the peptidyl-prolyl cis/trans isomerase Pin1 and highlight the importance of this oncogenic network in human disease pathogenesis.
      datePublished:2009-05-18T00:00:00Z
      dateModified:2009-05-18T00:00:00Z
      pageStart:2436
      pageEnd:2445
      sameAs:https://doi.org/10.1038/onc.2009.98
      keywords:
         PKB/Akt
         Pin1
         peptidyl-prolyl cis/trans isomerase
         breast cancer
         Medicine/Public Health
         general
         Internal Medicine
         Cell Biology
         Human Genetics
         Oncology
         Apoptosis
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig5_HTML.jpg
      isPartOf:
         name:Oncogene
         issn:
            1476-5594
            0950-9232
         volumeNumber:28
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Y Liao
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Y Wei
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:X Zhou
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
                  name:Cancer Hospital, Fudan University
                  address:
                     name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:J -Y Yang
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:C Dai
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Y -J Chen
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
                  name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
                  address:
                     name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:N K Agarwal
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:D Sarbassov
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:D Shi
            affiliation:
                  name:Cancer Hospital, Fudan University
                  address:
                     name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:D Yu
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:M -C Hung
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
                  name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
                  address:
                     name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
                     type:PostalAddress
                  type:Organization
                  name:Asia University
                  address:
                     name:Asia University, Taichung, Taiwan
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Oncogene
      issn:
         1476-5594
         0950-9232
      volumeNumber:28
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:Cancer Hospital, Fudan University
      address:
         name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
      address:
         name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:Cancer Hospital, Fudan University
      address:
         name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
      address:
         name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
         type:PostalAddress
      name:Asia University
      address:
         name:Asia University, Taichung, Taiwan
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Y Liao
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Y Wei
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:X Zhou
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
            name:Cancer Hospital, Fudan University
            address:
               name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
               type:PostalAddress
            type:Organization
      name:J -Y Yang
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:C Dai
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:Y -J Chen
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
            name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
            address:
               name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
               type:PostalAddress
            type:Organization
      name:N K Agarwal
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:D Sarbassov
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:D Shi
      affiliation:
            name:Cancer Hospital, Fudan University
            address:
               name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
               type:PostalAddress
            type:Organization
      name:D Yu
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:M -C Hung
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
            name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
            address:
               name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
               type:PostalAddress
            type:Organization
            name:Asia University
            address:
               name:Asia University, Taichung, Taiwan
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
      name:Asia University, Taichung, Taiwan
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(1)

• https://twitter.com/oncogenejournal

External Links {🔗}(183)

• What's the financial gain of https://link.springer.com/article/10.1038/onc.2009.98?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle?
• What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8978681?
• What's the financial gain of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC452479?
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Mechanism%20of%20activation%20of%20protein%20kinase%20B%20by%20insulin%20and%20IGF-1&journal=EMBO%20J&volume=15&pages=6541-6551&publication_year=1996&author=Alessi%2CDR&author=Andjelkovic%2CM&author=Caudwell%2CB&author=Cron%2CP&author=Morrice%2CN&author=Cohen%2CP
• How much does https://doi.org/10.1016%2FS0002-9440%2810%2963731-5 bring in each month?
• Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15111319
• Learn how profitable http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615639 is on a monthly basis
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Prevalent%20overexpression%20of%20prolyl%20isomerase%20Pin1%20in%20human%20cancers&journal=Am%20J%20Pathol&doi=10.1016%2FS0002-9440%2810%2963731-5&volume=164&pages=1727-1737&publication_year=2004&author=Bao%2CL&author=Kimzey%2CA&author=Sauter%2CG&author=Sowadski%2CJM&author=Lu%2CKP&author=Wang%2CDG?
• Learn about the earnings of https://doi.org/10.1016%2Fj.molcel.2005.03.020
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15837416 pull in monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20Akt%2FPKB%20Ser473%20phosphorylation&journal=Mol%20Cell&doi=10.1016%2Fj.molcel.2005.03.020&volume=18&pages=143-145&publication_year=2005&author=Bayascas%2CJR&author=Alessi%2CDR make?
• https://doi.org/10.1038%2Fsj.onc.1201947 income
• How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9690513?
• How much does http://scholar.google.com/scholar_lookup?&title=Akt%20activation%20by%20growth%20factors%20is%20a%20multiple-step%20process%3A%20the%20role%20of%20the%20PH%20domain&journal=Oncogene&doi=10.1038%2Fsj.onc.1201947&volume=17&pages=313-325&publication_year=1998&author=Bellacosa%2CA&author=Chan%2CTO&author=Ahmed%2CNN&author=Datta%2CK&author=Malstrom%2CS&author=Stokoe%2CD generate monthly?
• Earnings of https://doi.org/10.1016%2FS0065-230X%2805%2994002-5
• What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16095999?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Activation%20of%20AKT%20kinases%20in%20cancer%3A%20implications%20for%20therapeutic%20targeting&journal=Adv%20Cancer%20Res&doi=10.1016%2FS0065-230X%2805%2994002-5&volume=94&pages=29-86&publication_year=2005&author=Bellacosa%2CA&author=Kumar%2CCC&author=Di%20Cristofano%2CA&author=Testa%2CJR generate?
• Explore the financials of https://doi.org/10.1016%2Fj.devcel.2007.03.020
• What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17419990?
• What's the financial intake of http://scholar.google.com/scholar_lookup?&title=The%20two%20TORCs%20and%20Akt&journal=Dev%20Cell&doi=10.1016%2Fj.devcel.2007.03.020&volume=12&pages=487-502&publication_year=2007&author=Bhaskar%2CPT&author=Hay%2CN?
• What's the monthly money flow for https://doi.org/10.1016%2Fj.tibs.2004.03.006?
• Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15130559
• How much does http://scholar.google.com/scholar_lookup?&title=Advances%20in%20protein%20kinase%20B%20signalling%3A%20AKTion%20on%20multiple%20fronts&journal=Trends%20Biochem%20Sci&doi=10.1016%2Fj.tibs.2004.03.006&volume=29&pages=233-242&publication_year=2004&author=Brazil%2CDP&author=Yang%2CZZ&author=Hemmings%2CBA gross monthly?
• How much profit does https://doi.org/10.1016%2Fj.molcel.2007.02.017 make?
• Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17386267
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=PHLPP%20and%20a%20second%20isoform%2C%20PHLPP2%2C%20differentially%20attenuate%20the%20amplitude%20of%20Akt%20signaling%20by%20regulating%20distinct%20Akt%20isoforms&journal=Mol%20Cell&doi=10.1016%2Fj.molcel.2007.02.017&volume=25&pages=917-931&publication_year=2007&author=Brognard%2CJ&author=Sierecki%2CE&author=Gao%2CT&author=Newton%2CAC
• Discover the revenue of https://doi.org/10.1189%2Fjlb.1202629
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12773501 pull in?
• How much profit is http://scholar.google.com/scholar_lookup?&title=Decisions%20on%20life%20and%20death%3A%20FOXO%20Forkhead%20transcription%20factors%20are%20in%20command%20when%20PKB%2FAkt%20is%20off%20duty&journal=J%20Leukoc%20Biol&doi=10.1189%2Fjlb.1202629&volume=73&pages=689-701&publication_year=2003&author=Burgering%2CBM&author=Medema%2CRH making per month?
• https://doi.org/10.1038%2Fnature05933's financial summary
• Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17611497
• Income figures for http://scholar.google.com/scholar_lookup?&title=A%20transforming%20mutation%20in%20the%20pleckstrin%20homology%20domain%20of%20AKT1%20in%20cancer&journal=Nature&doi=10.1038%2Fnature05933&volume=448&pages=439-444&publication_year=2007&author=Carpten%2CJD&author=Faber%2CAL&author=Horn%2CC&author=Donoho%2CGP&author=Briggs%2CSL&author=Robbins%2CCM
• Discover the revenue of https://doi.org/10.1126%2Fscience.1118947
• How much cash flow does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16224021 have monthly?
• What's the income of http://scholar.google.com/scholar_lookup?&title=Akt-mediated%20phosphorylation%20of%20EZH2%20suppresses%20methylation%20of%20lysine%2027%20in%20histone%20H3&journal=Science&doi=10.1126%2Fscience.1118947&volume=310&pages=306-310&publication_year=2005&author=Cha%2CTL&author=Zhou%2CBP&author=Xia%2CW&author=Wu%2CY&author=Yang%2CCC&author=Chen%2CCT?
• What's the monthly income of https://doi.org/10.1146%2Fannurev.biochem.68.1.965?
• How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10872470 making per month?
• How much profit does http://scholar.google.com/scholar_lookup?&title=AKT%2FPKB%20and%20other%20D3%20phosphoinositide-regulated%20kinases%3A%20kinase%20activation%20by%20phosphoinositide-dependent%20phosphorylation&journal=Annu%20Rev%20Biochem&doi=10.1146%2Fannurev.biochem.68.1.965&volume=68&pages=965-1014&publication_year=1999&author=Chan%2CTO&author=Rittenhouse%2CSE&author=Tsichlis%2CPN make?
• Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11752635
• How profitable is http://scholar.google.com/scholar_lookup?&title=PDK2%3A%20a%20complex%20tail%20in%20one%20Akt&journal=Sci%20STKE&volume=2001&publication_year=2001&author=Chan%2CTO&author=Tsichlis%2CPN?
• How much profit does https://doi.org/10.1038%2Fnrc1819 generate?
• What's the monthly money flow for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16453012?
• What is the earnings of http://scholar.google.com/scholar_lookup?&title=Beyond%20PTEN%20mutations%3A%20the%20PI3%E2%80%89K%20pathway%20as%20an%20integrator%20of%20multiple%20inputs%20during%20tumorigenesis&journal=Nat%20Rev%20Cancer&doi=10.1038%2Fnrc1819&volume=6&pages=184-192&publication_year=2006&author=Cully%2CM&author=You%2CH&author=Levine%2CAJ&author=Mak%2CTW?
• How profitable is https://doi.org/10.1038%2Fsj.onc.1210202?
• What's the financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17322919?
• How much does http://scholar.google.com/scholar_lookup?&title=The%20phosphatidyl%20inositol%203-kinase%20signaling%20network%3A%20implications%20for%20human%20breast%20cancer&journal=Oncogene&doi=10.1038%2Fsj.onc.1210202&volume=26&pages=1338-1345&publication_year=2007&author=Dillon%2CRL&author=White%2CDE&author=Muller%2CWJ net monthly?
• What are the earnings of https://doi.org/10.1038%2Fsj.onc.1209099?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16288287 rake in every month?
• How profitable is http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20the%20Akt%20kinase%20by%20interacting%20proteins&journal=Oncogene&doi=10.1038%2Fsj.onc.1209099&volume=24&pages=7401-7409&publication_year=2005&author=Du%2CK&author=Tsichlis%2CPN?
• Profit of https://doi.org/10.1042%2FBST0350231
• What's the financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17371246?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Physiological%20roles%20of%20PKB%2FAkt%20isoforms%20in%20development%20and%20disease&journal=Biochem%20Soc%20Trans&doi=10.1042%2FBST0350231&volume=35&pages=231-235&publication_year=2007&author=Dummler%2CB&author=Hemmings%2CBA make?
• What are the total earnings of https://doi.org/10.1038%2Femboj.2008.120?
• How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18566586 make?
• See how much http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486276 makes per month
• http://scholar.google.com/scholar_lookup?&title=The%20mammalian%20target%20of%20rapamycin%20complex%202%20controls%20folding%20and%20stability%20of%20Akt%20and%20protein%20kinase%20C&journal=EMBO%20J&doi=10.1038%2Femboj.2008.120&volume=27&pages=1932-1943&publication_year=2008&author=Facchinetti%2CV&author=Ouyang%2CW&author=Wei%2CH&author=Soto%2CN&author=Lazorchak%2CA&author=Gould%2CC income
• How much income does https://doi.org/10.2174%2F156800908784293622 have?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18473735 gross monthly?
• What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Phosphorylation-specific%20prolyl%20isomerase%20Pin1%20as%20a%20new%20diagnostic%20and%20therapeutic%20target%20for%20cancer&journal=Curr%20Cancer%20Drug%20Targets&doi=10.2174%2F156800908784293622&volume=8&pages=223-229&publication_year=2008&author=Finn%2CG&author=Lu%2CKP?
• Profit of https://doi.org/10.1016%2Fj.molcel.2005.03.008
• How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15808505 generate?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=PHLPP%3A%20a%20phosphatase%20that%20directly%20dephosphorylates%20Akt%2C%20promotes%20apoptosis%2C%20and%20suppresses%20tumor%20growth&journal=Mol%20Cell&doi=10.1016%2Fj.molcel.2005.03.008&volume=18&pages=13-24&publication_year=2005&author=Gao%2CT&author=Furnari%2CF&author=Newton%2CAC produce monthly?
• Financial intake of https://doi.org/10.1016%2Fj.molmed.2005.06.007
• How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16002336 produce monthly?
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=An%20expanding%20role%20for%20mTOR%20in%20cancer&journal=Trends%20Mol%20Med&doi=10.1016%2Fj.molmed.2005.06.007&volume=11&pages=353-361&publication_year=2005&author=Guertin%2CDA&author=Sabatini%2CDM
• How much money does https://doi.org/10.1038%2Femboj.2008.119 generate?
• What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18566587?
• What's the income generated by http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486275 each month?
• http://scholar.google.com/scholar_lookup?&title=Essential%20function%20of%20TORC2%20in%20PKC%20and%20Akt%20turn%20motif%20phosphorylation%2C%20maturation%20and%20signalling&journal=EMBO%20J&doi=10.1038%2Femboj.2008.119&volume=27&pages=1919-1931&publication_year=2008&author=Ikenoue%2CT&author=Inoki%2CK&author=Yang%2CQ&author=Zhou%2CX&author=Guan%2CKL's revenue stream
• What's the income generated by https://doi.org/10.1073%2Fpnas.0408864102 each month?
• Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15647370
• How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC545580 rake in every month?
• How much money does http://scholar.google.com/scholar_lookup?&title=Phosphatidylinositol%203-kinase%20mutations%20identified%20in%20human%20cancer%20are%20oncogenic&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.0408864102&volume=102&pages=802-807&publication_year=2005&author=Kang%2CS&author=Bader%2CAG&author=Vogt%2CPK generate?
• How much does https://link.springer.com/doi/10.1007/s001099900050 earn?
• How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10569203 generate?
• Profit of http://scholar.google.com/scholar_lookup?&title=Forkhead%20transcription%20factors%3A%20new%20insights%20into%20protein%20kinase%20B%20%28c-akt%29%20signaling&journal=J%20Mol%20Med&doi=10.1007%2Fs001099900050&volume=77&pages=656-665&publication_year=1999&author=Kops%2CGJ&author=Burgering%2CBM
• What's the profit of https://doi.org/10.1128%2FMCB.23.19.6836-6848.2003?
• http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12972603's total income per month
• How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC193925 generate monthly?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20the%20activity%20of%20p38%20mitogen-activated%20protein%20kinase%20by%20Akt%20in%20cancer%20and%20adenoviral%20protein%20E1A-mediated%20sensitization%20to%20apoptosis&journal=Mol%20Cell%20Biol&doi=10.1128%2FMCB.23.19.6836-6848.2003&volume=23&pages=6836-6848&publication_year=2003&author=Liao%2CY&author=Hung%2CMC generate?
• Earnings of https://doi.org/10.1073%2Fpnas.060025397
• Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10759547
• How much money does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC18221 make?
• How much does http://scholar.google.com/scholar_lookup?&title=Beta-catenin%2C%20a%20novel%20prognostic%20marker%20for%20breast%20cancer%3A%20its%20roles%20in%20cyclin%20D1%20expression%20and%20cancer%20progression&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.060025397&volume=97&pages=4262-4266&publication_year=2000&author=Lin%2CSY&author=Xia%2CW&author=Wang%2CJC&author=Kwong%2CKY&author=Spohn%2CB&author=Wen%2CY make?
• What's the income generated by https://doi.org/10.1002%2Fmc.20216 each month?
• What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16652378?
• Earnings of http://scholar.google.com/scholar_lookup?&title=Targeting%20carcinogenesis%3A%20a%20role%20for%20the%20prolyl%20isomerase%20Pin1%3F&journal=Mol%20Carcinog&doi=10.1002%2Fmc.20216&volume=45&pages=397-402&publication_year=2006&author=Lu%2CKP&author=Suizu%2CF&author=Zhou%2CXZ&author=Finn%2CG&author=Lam%2CP&author=Wulf%2CG
• https://doi.org/10.1038%2Fnrm2261 income
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17878917 generate monthly?
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=The%20prolyl%20isomerase%20PIN1%3A%20a%20pivotal%20new%20twist%20in%20phosphorylation%20signalling%20and%20disease&journal=Nat%20Rev%20Mol%20Cell%20Biol&doi=10.1038%2Fnrm2261&volume=8&pages=904-916&publication_year=2007&author=Lu%2CKP&author=Zhou%2CXZ have monthly?
• Explore the financials of https://doi.org/10.1126%2Fscience.283.5406.1325
• What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10037602?
• What's http://scholar.google.com/scholar_lookup?&title=Function%20of%20WW%20domains%20as%20phosphoserine-%20or%20phosphothreonine-binding%20modules&journal=Science&doi=10.1126%2Fscience.283.5406.1325&volume=283&pages=1325-1328&publication_year=1999&author=Lu%2CPJ&author=Zhou%2CXZ&author=Shen%2CM&author=Lu%2CKP's gross income?
• Monthly income for https://doi.org/10.1016%2FS1535-6108%2803%2900248-4
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14585353 pull in monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=Targeting%20the%20PI3K-Akt%20pathway%20in%20human%20cancer%3A%20rationale%20and%20promise&journal=Cancer%20Cell&doi=10.1016%2FS1535-6108%2803%2900248-4&volume=4&pages=257-262&publication_year=2003&author=Luo%2CJ&author=Manning%2CBD&author=Cantley%2CLC make?
• Revenue of https://doi.org/10.1016%2Fj.cell.2007.06.009
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17604717 earn?
• What's http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756685's gross income?
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=AKT%2FPKB%20signaling%3A%20navigating%20downstream&journal=Cell&doi=10.1016%2Fj.cell.2007.06.009&volume=129&pages=1261-1274&publication_year=2007&author=Manning%2CBD&author=Cantley%2CLC have monthly?
• https://doi.org/10.1158%2F0008-5472.CAN-06-3782's total income per month
• Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17210696
• Get to know http://scholar.google.com/scholar_lookup?&title=Akt1%20ablation%20inhibits%2C%20whereas%20Akt2%20ablation%20accelerates%2C%20the%20development%20of%20mammary%20adenocarcinomas%20in%20mouse%20mammary%20tumor%20virus%20%28MMTV%29-ErbB2%2Fneu%20and%20MMTV-polyoma%20middle%20T%20transgenic%20mice&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-06-3782&volume=67&pages=167-177&publication_year=2007&author=Maroulakou%2CIG&author=Oemler%2CW&author=Naber%2CSP&author=Tsichlis%2CPN's earnings
• How much does https://doi.org/10.1074%2Fjbc.273.45.29864 rake in every month?
• What's the monthly money flow for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9792703?
• Income figures for http://scholar.google.com/scholar_lookup?&title=Cyclin%20D%20expression%20is%20controlled%20post-transcriptionally%20via%20a%20phosphatidylinositol%203-kinase%2FAkt-dependent%20pathway&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.273.45.29864&volume=273&pages=29864-29872&publication_year=1998&author=Muise-Helmericks%2CR&author=Grimes%2CHL&author=Bellacosa%2CA&author=Malstrom%2CSE&author=Tsichlis%2CPN
• How much money does https://doi.org/10.1042%2Fbj20021626 make?
• What's the financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12495431?
• Explore the financials of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223206
• How much money does http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20ABC%20kinases%20by%20phosphorylation%3A%20protein%20kinase%20C%20as%20a%20paradigm&journal=Biochem%20J&doi=10.1042%2Fbj20021626&volume=370&pages=361-371&publication_year=2003&author=Newton%2CAC make?
• https://doi.org/10.1126%2Fscience.1106148 income
• How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15718470 make?
• What is the earnings of http://scholar.google.com/scholar_lookup?&title=Phosphorylation%20and%20regulation%20of%20Akt%2FPKB%20by%20the%20rictor-mTOR%20complex&journal=Science&doi=10.1126%2Fscience.1106148&volume=307&pages=1098-1101&publication_year=2005&author=Sarbassov%2CDD&author=Guertin%2CDA&author=Ali%2CSM&author=Sabatini%2CDM?
• What are the total earnings of https://doi.org/10.1159%2F000096289?
• http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17047397 income
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=Mutational%20analysis%20of%20AKT1%2C%20AKT2%20and%20AKT3%20genes%20in%20common%20human%20carcinomas&journal=Oncology&doi=10.1159%2F000096289&volume=70&pages=285-289&publication_year=2006&author=Soung%2CYH&author=Lee%2CJW&author=Nam%2CSW&author=Lee%2CJY&author=Yoo%2CNJ&author=Lee%2CSH have monthly?
• How much does https://link.springer.com/doi/10.1007/s00018-007-7270-0 bring in each month?
• See how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17965833 makes per month
• http://scholar.google.com/scholar_lookup?&title=Prolyl%20isomerase%2C%20Pin1%3A%20new%20findings%20of%20post-translational%20modifications%20and%20physiological%20substrates%20in%20cancer%2C%20asthma%20and%20Alzheimer%2Fs%20disease&journal=Cell%20Mol%20Life%20Sci&doi=10.1007%2Fs00018-007-7270-0&volume=65&pages=359-375&publication_year=2008&author=Takahashi%2CK&author=Uchida%2CC&author=Shin%2CRW&author=Shimazaki%2CK&author=Uchida%2CT income
• How much cash flow does https://doi.org/10.1038%2Fsj.onc.1209100 have monthly?
• Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16288285 is on a monthly basis
• What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=AKT%20signaling%20in%20normal%20and%20malignant%20cells&journal=Oncogene&doi=10.1038%2Fsj.onc.1209100&volume=24&pages=7391-7393&publication_year=2005&author=Testa%2CJR&author=Tsichlis%2CPN?
• https://doi.org/10.2174%2F156800908783497140's financial summary
• http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18288941's total income per month
• Explore the financials of http://scholar.google.com/scholar_lookup?&title=Deregulation%20of%20the%20Akt%20pathway%20in%20human%20cancer&journal=Curr%20Cancer%20Drug%20Targets&doi=10.2174%2F156800908783497140&volume=8&pages=27-36&publication_year=2008&author=Tokunaga%2CE&author=Oki%2CE&author=Egashira%2CA&author=Sadanaga%2CN&author=Morita%2CM&author=Kakeji%2CY
• Financial intake of https://doi.org/10.1038%2Fsj.emboj.7600323
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15257284 make?
• How much profit does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514501 generate?
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=Modeling%20breast%20cancer%20in%20vivo%20and%20ex%20vivo%20reveals%20an%20essential%20role%20of%20Pin1%20in%20tumorigenesis&journal=EMBO%20J&doi=10.1038%2Fsj.emboj.7600323&volume=23&pages=3397-3407&publication_year=2004&author=Wulf%2CG&author=Garg%2CP&author=Liou%2CYC&author=Iglehart%2CD&author=Lu%2CKP have monthly?
• What is the monthly revenue of https://doi.org/10.1158%2F1078-0432.CCR-03-0527?
• How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15173090 generate?
• How much profit is http://scholar.google.com/scholar_lookup?&title=Phosphorylation%2Fcytoplasmic%20localization%20of%20p21Cip1%2FWAF1%20is%20associated%20with%20HER2%2Fneu%20overexpression%20and%20provides%20a%20novel%20combination%20predictor%20for%20poor%20prognosis%20in%20breast%20cancer%20patients&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-03-0527&volume=10&pages=3815-3824&publication_year=2004&author=Xia%2CW&author=Chen%2CJS&author=Zhou%2CX&author=Sun%2CPR&author=Lee%2CDF&author=Liao%2CY making per month?
• How much does https://doi.org/10.1042%2Fbst0320350 net monthly?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15046607 pull in?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Physiological%20functions%20of%20protein%20kinase%20B%2FAkt&journal=Biochem%20Soc%20Trans&doi=10.1042%2Fbst0320350&volume=32&pages=350-354&publication_year=2004&author=Yang%2CZZ&author=Tschopp%2CO&author=Baudry%2CA&author=Dummler%2CB&author=Hynx%2CD&author=Hemmings%2CBA?
• How profitable is https://doi.org/10.1038%2Fncb1110?
• How much income is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15048125 earning monthly?
• Profit of http://scholar.google.com/scholar_lookup?&title=A%20signalling%20pathway%20controlling%20c-Myc%20degradation%20that%20impacts%20oncogenic%20transformation%20of%20human%20cells&journal=Nat%20Cell%20Biol&doi=10.1038%2Fncb1110&volume=6&pages=308-318&publication_year=2004&author=Yeh%2CE&author=Cunningham%2CM&author=Arnold%2CH&author=Chasse%2CD&author=Monteith%2CT&author=Ivaldi%2CG
• How much does https://doi.org/10.1038%2Fnrc2107 generate monthly?
• What's the financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17410202?
• See how much http://scholar.google.com/scholar_lookup?&title=PIN1%2C%20the%20cell%20cycle%20and%20cancer&journal=Nat%20Rev%20Cancer&doi=10.1038%2Fnrc2107&volume=7&pages=381-388&publication_year=2007&author=Yeh%2CES&author=Means%2CAR makes per month
• What are the total earnings of https://doi.org/10.1038%2Fnature01120?
• How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12397362 making per month?
• How much money does http://scholar.google.com/scholar_lookup?&title=The%20prolyl%20isomerase%20Pin1%20reveals%20a%20mechanism%20to%20control%20p53%20functions%20after%20genotoxic%20insults&journal=Nature&doi=10.1038%2Fnature01120&volume=419&pages=853-857&publication_year=2002&author=Zacchi%2CP&author=Gostissa%2CM&author=Uchida%2CT&author=Salvagno%2CC&author=Avolio%2CF&author=Volinia%2CS make?
• How much cash flow does https://citation-needed.springer.com/v2/references/10.1038/onc.2009.98?format=refman&flavour=references have monthly?
• What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Y%20Liao?
• What are the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Y%20Liao%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Y%20Wei's gross income?
• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Y%20Wei%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
• What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=X%20Zhou?
• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22X%20Zhou%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
• Learn about the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=J%20-Y%20Yang
• How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22J%20-Y%20Yang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=C%20Dai generate?
• Get to know https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22C%20Dai%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's earnings
• Profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Y%20-J%20Chen
• How much cash flow does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Y%20-J%20Chen%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have monthly?
• See how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=N%20K%20Agarwal makes per month
• How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22N%20K%20Agarwal%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
• What's the profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=D%20Sarbassov?
• Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22D%20Sarbassov%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
• Get to know what's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=D%20Shi
• Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22D%20Shi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=D%20Yu produce monthly?
• Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22D%20Yu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What is the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=M%20-C%20Hung?
• What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22M%20-C%20Hung%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the total monthly financial gain of https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_BFonc200998_MOESM11_ESM.jpg?
• How much profit does https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_BFonc200998_MOESM12_ESM.jpg make?
• https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_BFonc200998_MOESM13_ESM.jpg income
• Learn about the earnings of https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_BFonc200998_MOESM14_ESM.jpg
• How much does https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_BFonc200998_MOESM15_ESM.jpg net monthly?
• How much profit does https://s100.copyright.com/AppDispatchServlet?title=Peptidyl-prolyl%20cis%2Ftrans%20isomerase%20Pin1%20is%20critical%20for%20the%20regulation%20of%20PKB%2FAkt%20stability%20and%20activation%20phosphorylation&author=Y%20Liao%20et%20al&contentID=10.1038%2Fonc.2009.98©right=Macmillan%20Publishers%20Limited&publication=0950-9232&publicationDate=2009-05-18&publisherName=SpringerNature&orderBeanReset=true make?
• Profit of https://citation-needed.springer.com/v2/references/10.1038/onc.2009.98?format=refman&flavour=citation
• What is the monthly revenue of https://doi.org/10.1186/s13045-021-01137-8?
• What is the earnings of https://doi.org/10.1038/s41598-021-88478-z?
• How much cash flow does https://doi.org/10.1186/s13045-018-0611-7 have monthly?
• What's the income generated by https://doi.org/10.1038/s41467-018-05402-2 each month?
• What's the income generated by https://doi.org/10.1038/srep43639 each month?
• How much profit does https://www.protocols.io/ make?
• What are the total earnings of https://www.natureindex.com/?
• How much profit does http://www.naturechina.com generate?
• What are the total earnings of https://www.natureasia.com/ja-jp?

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref