NATURE . COM {}

Matching Content Categories {📚}

• Education
• Health & Fitness
• Telecommunications

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,554,915 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$536,300 per month
Estimations show Nature.com's display ad online revenue falls between $357,503 and $983,134 per month.

Keywords {🔍}

article, pubmed, cas, google, scholar, cancer, akt, pin, nature, protein, kinase, cell, isomerase, phosphorylation, zhou, access, oncogene, breast, central, stability, human, mol, university, regulation, department, content, activation, liao, usa, center, supplementary, cookies, information, yang, chen, hung, expression, prolyl, tsichlis, privacy, peptidylprolyl, cistrans, pkbakt, role, multiple, open, signalling, targeting, biochem, sci,

Topics {✒️}

nature portfolio research development award permissions reprints privacy policy inhibit cancer-driving pathways author information authors editing mmtv-polyoma middle advertising nature 448 nature 419 nature language improvement social media phosphatidylinositol 3-kinase/akt-dependent pathway scientific publication china medical university akt-ps473 status combined prolyl isomerase pin1 serine/threonine protein kinase phosphorylated thr-pro motifs epigallocatechin-3-gallate induces apoptosis personal data springerlink instant access d3 phosphoinositide-regulated kinases dr lu kp data protection akt/pkb ser473 phosphorylation permissions multiple cancer types china akt-mtor signalling axis multiple-step process pin1 mef cells modeling breast cancer suppresses tumor growth arsenic targets pin1 alessi dr human breast cancer breast cancer patients homologue pin1 knockout testa jr privacy supplementary figure s2 supplementary figure s3 prolyl isomerase repressing pin1 expression phosphoinositide-dependent phosphorylation akt protein stability forkhead transcription factors

Questions {❓}

• Targeting carcinogenesis: a role for the prolyl isomerase Pin1?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation
         description:The serine/threonine protein kinase B (PKB, also known as Akt) plays a pivotal role in diverse cellular functions. Elevated expression of activated Akt has been detected in a wide variety of human cancers; however, the mechanism of Akt protein stability regulation remains unclear. In this study, we showed a strong correlation between the expression levels of an oncogenic peptidyl-prolyl cis/trans isomerase Pin1 and levels of Akt phosphorylation at S473 in multiple cancer types (P<0.0001). Akt-pS473 status combined with Pin1 expression levels predicted a poorer prognosis than did either one alone in patients with breast cancer (P=0.0052). We further showed that Pin1 regulated Akt stability and phosphorylation on S473 through the phosphorylated Thr-Pro motifs of Akt. These motifs are conserved evolutionary and are required for the maintenance of Akt stability and its interaction with Pin1. In addition, repressing Pin1 expression through either homologue Pin1 knockout or small interfering RNA-mediated knockingdown compromised its ability to protect Akt from degradation. Our results show how Akt protein stability is regulated by the peptidyl-prolyl cis/trans isomerase Pin1 and highlight the importance of this oncogenic network in human disease pathogenesis.
         datePublished:2009-05-18T00:00:00Z
         dateModified:2009-05-18T00:00:00Z
         pageStart:2436
         pageEnd:2445
         sameAs:https://doi.org/10.1038/onc.2009.98
         keywords:
            PKB/Akt
            Pin1
            peptidyl-prolyl cis/trans isomerase
            breast cancer
            Medicine/Public Health
            general
            Internal Medicine
            Cell Biology
            Human Genetics
            Oncology
            Apoptosis
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig5_HTML.jpg
         isPartOf:
            name:Oncogene
            issn:
               1476-5594
               0950-9232
            volumeNumber:28
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Y Liao
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Y Wei
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:X Zhou
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
                     name:Cancer Hospital, Fudan University
                     address:
                        name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:J -Y Yang
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:C Dai
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Y -J Chen
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
                     name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
                     address:
                        name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:N K Agarwal
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:D Sarbassov
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:D Shi
               affiliation:
                     name:Cancer Hospital, Fudan University
                     address:
                        name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:D Yu
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:M -C Hung
               affiliation:
                     name:The University of Texas MD Anderson Cancer Center
                     address:
                        name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                        type:PostalAddress
                     type:Organization
                     name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
                     address:
                        name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
                        type:PostalAddress
                     type:Organization
                     name:Asia University
                     address:
                        name:Asia University, Taichung, Taiwan
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation
      description:The serine/threonine protein kinase B (PKB, also known as Akt) plays a pivotal role in diverse cellular functions. Elevated expression of activated Akt has been detected in a wide variety of human cancers; however, the mechanism of Akt protein stability regulation remains unclear. In this study, we showed a strong correlation between the expression levels of an oncogenic peptidyl-prolyl cis/trans isomerase Pin1 and levels of Akt phosphorylation at S473 in multiple cancer types (P<0.0001). Akt-pS473 status combined with Pin1 expression levels predicted a poorer prognosis than did either one alone in patients with breast cancer (P=0.0052). We further showed that Pin1 regulated Akt stability and phosphorylation on S473 through the phosphorylated Thr-Pro motifs of Akt. These motifs are conserved evolutionary and are required for the maintenance of Akt stability and its interaction with Pin1. In addition, repressing Pin1 expression through either homologue Pin1 knockout or small interfering RNA-mediated knockingdown compromised its ability to protect Akt from degradation. Our results show how Akt protein stability is regulated by the peptidyl-prolyl cis/trans isomerase Pin1 and highlight the importance of this oncogenic network in human disease pathogenesis.
      datePublished:2009-05-18T00:00:00Z
      dateModified:2009-05-18T00:00:00Z
      pageStart:2436
      pageEnd:2445
      sameAs:https://doi.org/10.1038/onc.2009.98
      keywords:
         PKB/Akt
         Pin1
         peptidyl-prolyl cis/trans isomerase
         breast cancer
         Medicine/Public Health
         general
         Internal Medicine
         Cell Biology
         Human Genetics
         Oncology
         Apoptosis
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_Article_BFonc200998_Fig5_HTML.jpg
      isPartOf:
         name:Oncogene
         issn:
            1476-5594
            0950-9232
         volumeNumber:28
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Y Liao
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Y Wei
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:X Zhou
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
                  name:Cancer Hospital, Fudan University
                  address:
                     name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:J -Y Yang
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:C Dai
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Y -J Chen
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
                  name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
                  address:
                     name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:N K Agarwal
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:D Sarbassov
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:D Shi
            affiliation:
                  name:Cancer Hospital, Fudan University
                  address:
                     name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:D Yu
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:M -C Hung
            affiliation:
                  name:The University of Texas MD Anderson Cancer Center
                  address:
                     name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
                     type:PostalAddress
                  type:Organization
                  name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
                  address:
                     name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
                     type:PostalAddress
                  type:Organization
                  name:Asia University
                  address:
                     name:Asia University, Taichung, Taiwan
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Oncogene
      issn:
         1476-5594
         0950-9232
      volumeNumber:28
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:Cancer Hospital, Fudan University
      address:
         name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
      address:
         name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:Cancer Hospital, Fudan University
      address:
         name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:The University of Texas MD Anderson Cancer Center
      address:
         name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
         type:PostalAddress
      name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
      address:
         name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
         type:PostalAddress
      name:Asia University
      address:
         name:Asia University, Taichung, Taiwan
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Y Liao
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Y Wei
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:X Zhou
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
            name:Cancer Hospital, Fudan University
            address:
               name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
               type:PostalAddress
            type:Organization
      name:J -Y Yang
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:C Dai
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:Y -J Chen
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
            name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
            address:
               name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
               type:PostalAddress
            type:Organization
      name:N K Agarwal
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:D Sarbassov
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:D Shi
      affiliation:
            name:Cancer Hospital, Fudan University
            address:
               name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
               type:PostalAddress
            type:Organization
      name:D Yu
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:M -C Hung
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
            name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital
            address:
               name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
               type:PostalAddress
            type:Organization
            name:Asia University
            address:
               name:Asia University, Taichung, Taiwan
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Pathology, Cancer Hospital, Fudan University, Shanghai, China
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and Hospital, Taichung, Taiwan
      name:Asia University, Taichung, Taiwan
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(1)

• https://twitter.com/oncogenejournal

External Links {🔗}(183)

• How much income does https://link.springer.com/article/10.1038/onc.2009.98?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle have?
• How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8978681 generate?
• Find out how much http://www.ncbi.nlm.nih.gov/pmc/articles/PMC452479 earns monthly
• How much money does http://scholar.google.com/scholar_lookup?&title=Mechanism%20of%20activation%20of%20protein%20kinase%20B%20by%20insulin%20and%20IGF-1&journal=EMBO%20J&volume=15&pages=6541-6551&publication_year=1996&author=Alessi%2CDR&author=Andjelkovic%2CM&author=Caudwell%2CB&author=Cron%2CP&author=Morrice%2CN&author=Cohen%2CP make?
• How much income does https://doi.org/10.1016%2FS0002-9440%2810%2963731-5 have?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15111319 earn?
• See how much http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615639 makes per month
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Prevalent%20overexpression%20of%20prolyl%20isomerase%20Pin1%20in%20human%20cancers&journal=Am%20J%20Pathol&doi=10.1016%2FS0002-9440%2810%2963731-5&volume=164&pages=1727-1737&publication_year=2004&author=Bao%2CL&author=Kimzey%2CA&author=Sauter%2CG&author=Sowadski%2CJM&author=Lu%2CKP&author=Wang%2CDG
• https://doi.org/10.1016%2Fj.molcel.2005.03.020's financial summary
• Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15837416
• What's the income of http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20Akt%2FPKB%20Ser473%20phosphorylation&journal=Mol%20Cell&doi=10.1016%2Fj.molcel.2005.03.020&volume=18&pages=143-145&publication_year=2005&author=Bayascas%2CJR&author=Alessi%2CDR?
• What are the total earnings of https://doi.org/10.1038%2Fsj.onc.1201947?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9690513 rake in every month?
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Akt%20activation%20by%20growth%20factors%20is%20a%20multiple-step%20process%3A%20the%20role%20of%20the%20PH%20domain&journal=Oncogene&doi=10.1038%2Fsj.onc.1201947&volume=17&pages=313-325&publication_year=1998&author=Bellacosa%2CA&author=Chan%2CTO&author=Ahmed%2CNN&author=Datta%2CK&author=Malstrom%2CS&author=Stokoe%2CD?
• See how much https://doi.org/10.1016%2FS0065-230X%2805%2994002-5 makes per month
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16095999 pull in monthly?
• How much money does http://scholar.google.com/scholar_lookup?&title=Activation%20of%20AKT%20kinases%20in%20cancer%3A%20implications%20for%20therapeutic%20targeting&journal=Adv%20Cancer%20Res&doi=10.1016%2FS0065-230X%2805%2994002-5&volume=94&pages=29-86&publication_year=2005&author=Bellacosa%2CA&author=Kumar%2CCC&author=Di%20Cristofano%2CA&author=Testa%2CJR make?
• How much cash flow does https://doi.org/10.1016%2Fj.devcel.2007.03.020 have monthly?
• What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17419990?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=The%20two%20TORCs%20and%20Akt&journal=Dev%20Cell&doi=10.1016%2Fj.devcel.2007.03.020&volume=12&pages=487-502&publication_year=2007&author=Bhaskar%2CPT&author=Hay%2CN?
• How much profit does https://doi.org/10.1016%2Fj.tibs.2004.03.006 generate?
• Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15130559
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Advances%20in%20protein%20kinase%20B%20signalling%3A%20AKTion%20on%20multiple%20fronts&journal=Trends%20Biochem%20Sci&doi=10.1016%2Fj.tibs.2004.03.006&volume=29&pages=233-242&publication_year=2004&author=Brazil%2CDP&author=Yang%2CZZ&author=Hemmings%2CBA
• See how much https://doi.org/10.1016%2Fj.molcel.2007.02.017 makes per month
• How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17386267 making per month?
• How much money does http://scholar.google.com/scholar_lookup?&title=PHLPP%20and%20a%20second%20isoform%2C%20PHLPP2%2C%20differentially%20attenuate%20the%20amplitude%20of%20Akt%20signaling%20by%20regulating%20distinct%20Akt%20isoforms&journal=Mol%20Cell&doi=10.1016%2Fj.molcel.2007.02.017&volume=25&pages=917-931&publication_year=2007&author=Brognard%2CJ&author=Sierecki%2CE&author=Gao%2CT&author=Newton%2CAC generate?
• How much does https://doi.org/10.1189%2Fjlb.1202629 earn?
• What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12773501?
• How profitable is http://scholar.google.com/scholar_lookup?&title=Decisions%20on%20life%20and%20death%3A%20FOXO%20Forkhead%20transcription%20factors%20are%20in%20command%20when%20PKB%2FAkt%20is%20off%20duty&journal=J%20Leukoc%20Biol&doi=10.1189%2Fjlb.1202629&volume=73&pages=689-701&publication_year=2003&author=Burgering%2CBM&author=Medema%2CRH?
• What's the profit of https://doi.org/10.1038%2Fnature05933?
• Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17611497
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=A%20transforming%20mutation%20in%20the%20pleckstrin%20homology%20domain%20of%20AKT1%20in%20cancer&journal=Nature&doi=10.1038%2Fnature05933&volume=448&pages=439-444&publication_year=2007&author=Carpten%2CJD&author=Faber%2CAL&author=Horn%2CC&author=Donoho%2CGP&author=Briggs%2CSL&author=Robbins%2CCM have monthly?
• Learn how profitable https://doi.org/10.1126%2Fscience.1118947 is on a monthly basis
• How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16224021 generate?
• What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Akt-mediated%20phosphorylation%20of%20EZH2%20suppresses%20methylation%20of%20lysine%2027%20in%20histone%20H3&journal=Science&doi=10.1126%2Fscience.1118947&volume=310&pages=306-310&publication_year=2005&author=Cha%2CTL&author=Zhou%2CBP&author=Xia%2CW&author=Wu%2CY&author=Yang%2CCC&author=Chen%2CCT?
• https://doi.org/10.1146%2Fannurev.biochem.68.1.965's financial summary
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10872470 pull in monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=AKT%2FPKB%20and%20other%20D3%20phosphoinositide-regulated%20kinases%3A%20kinase%20activation%20by%20phosphoinositide-dependent%20phosphorylation&journal=Annu%20Rev%20Biochem&doi=10.1146%2Fannurev.biochem.68.1.965&volume=68&pages=965-1014&publication_year=1999&author=Chan%2CTO&author=Rittenhouse%2CSE&author=Tsichlis%2CPN pull in monthly?
• Income figures for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11752635
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=PDK2%3A%20a%20complex%20tail%20in%20one%20Akt&journal=Sci%20STKE&volume=2001&publication_year=2001&author=Chan%2CTO&author=Tsichlis%2CPN?
• Get to know what's the income of https://doi.org/10.1038%2Fnrc1819
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16453012 pull in monthly?
• Income figures for http://scholar.google.com/scholar_lookup?&title=Beyond%20PTEN%20mutations%3A%20the%20PI3%E2%80%89K%20pathway%20as%20an%20integrator%20of%20multiple%20inputs%20during%20tumorigenesis&journal=Nat%20Rev%20Cancer&doi=10.1038%2Fnrc1819&volume=6&pages=184-192&publication_year=2006&author=Cully%2CM&author=You%2CH&author=Levine%2CAJ&author=Mak%2CTW
• What's the monthly money flow for https://doi.org/10.1038%2Fsj.onc.1210202?
• What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17322919?
• How much does http://scholar.google.com/scholar_lookup?&title=The%20phosphatidyl%20inositol%203-kinase%20signaling%20network%3A%20implications%20for%20human%20breast%20cancer&journal=Oncogene&doi=10.1038%2Fsj.onc.1210202&volume=26&pages=1338-1345&publication_year=2007&author=Dillon%2CRL&author=White%2CDE&author=Muller%2CWJ generate monthly?
• How much revenue does https://doi.org/10.1038%2Fsj.onc.1209099 bring in?
• http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16288287 income
• Revenue of http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20the%20Akt%20kinase%20by%20interacting%20proteins&journal=Oncogene&doi=10.1038%2Fsj.onc.1209099&volume=24&pages=7401-7409&publication_year=2005&author=Du%2CK&author=Tsichlis%2CPN
• How much does https://doi.org/10.1042%2FBST0350231 rake in every month?
• Financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17371246
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Physiological%20roles%20of%20PKB%2FAkt%20isoforms%20in%20development%20and%20disease&journal=Biochem%20Soc%20Trans&doi=10.1042%2FBST0350231&volume=35&pages=231-235&publication_year=2007&author=Dummler%2CB&author=Hemmings%2CBA is on a monthly basis
• How much money does https://doi.org/10.1038%2Femboj.2008.120 generate?
• How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18566586?
• See how much http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486276 makes per month
• How much profit does http://scholar.google.com/scholar_lookup?&title=The%20mammalian%20target%20of%20rapamycin%20complex%202%20controls%20folding%20and%20stability%20of%20Akt%20and%20protein%20kinase%20C&journal=EMBO%20J&doi=10.1038%2Femboj.2008.120&volume=27&pages=1932-1943&publication_year=2008&author=Facchinetti%2CV&author=Ouyang%2CW&author=Wei%2CH&author=Soto%2CN&author=Lazorchak%2CA&author=Gould%2CC make?
• How profitable is https://doi.org/10.2174%2F156800908784293622?
• How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18473735 produce monthly?
• Find out how much http://scholar.google.com/scholar_lookup?&title=Phosphorylation-specific%20prolyl%20isomerase%20Pin1%20as%20a%20new%20diagnostic%20and%20therapeutic%20target%20for%20cancer&journal=Curr%20Cancer%20Drug%20Targets&doi=10.2174%2F156800908784293622&volume=8&pages=223-229&publication_year=2008&author=Finn%2CG&author=Lu%2CKP earns monthly
• What is the monthly revenue of https://doi.org/10.1016%2Fj.molcel.2005.03.008?
• See how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15808505 makes per month
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=PHLPP%3A%20a%20phosphatase%20that%20directly%20dephosphorylates%20Akt%2C%20promotes%20apoptosis%2C%20and%20suppresses%20tumor%20growth&journal=Mol%20Cell&doi=10.1016%2Fj.molcel.2005.03.008&volume=18&pages=13-24&publication_year=2005&author=Gao%2CT&author=Furnari%2CF&author=Newton%2CAC is on a monthly basis
• How much does https://doi.org/10.1016%2Fj.molmed.2005.06.007 generate monthly?
• Profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16002336
• Get to know http://scholar.google.com/scholar_lookup?&title=An%20expanding%20role%20for%20mTOR%20in%20cancer&journal=Trends%20Mol%20Med&doi=10.1016%2Fj.molmed.2005.06.007&volume=11&pages=353-361&publication_year=2005&author=Guertin%2CDA&author=Sabatini%2CDM's earnings
• How much profit is https://doi.org/10.1038%2Femboj.2008.119 making per month?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18566587 pull in?
• What's the revenue for http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486275?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Essential%20function%20of%20TORC2%20in%20PKC%20and%20Akt%20turn%20motif%20phosphorylation%2C%20maturation%20and%20signalling&journal=EMBO%20J&doi=10.1038%2Femboj.2008.119&volume=27&pages=1919-1931&publication_year=2008&author=Ikenoue%2CT&author=Inoki%2CK&author=Yang%2CQ&author=Zhou%2CX&author=Guan%2CKL?
• What's the monthly money flow for https://doi.org/10.1073%2Fpnas.0408864102?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15647370 generate monthly?
• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC545580's total income per month
• How much does http://scholar.google.com/scholar_lookup?&title=Phosphatidylinositol%203-kinase%20mutations%20identified%20in%20human%20cancer%20are%20oncogenic&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.0408864102&volume=102&pages=802-807&publication_year=2005&author=Kang%2CS&author=Bader%2CAG&author=Vogt%2CPK rake in every month?
• What's the income generated by https://link.springer.com/doi/10.1007/s001099900050 each month?
• What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10569203's gross income?
• How much does http://scholar.google.com/scholar_lookup?&title=Forkhead%20transcription%20factors%3A%20new%20insights%20into%20protein%20kinase%20B%20%28c-akt%29%20signaling&journal=J%20Mol%20Med&doi=10.1007%2Fs001099900050&volume=77&pages=656-665&publication_year=1999&author=Kops%2CGJ&author=Burgering%2CBM pull in?
• How much income does https://doi.org/10.1128%2FMCB.23.19.6836-6848.2003 have?
• What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12972603?
• How much profit is http://www.ncbi.nlm.nih.gov/pmc/articles/PMC193925 making per month?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20the%20activity%20of%20p38%20mitogen-activated%20protein%20kinase%20by%20Akt%20in%20cancer%20and%20adenoviral%20protein%20E1A-mediated%20sensitization%20to%20apoptosis&journal=Mol%20Cell%20Biol&doi=10.1128%2FMCB.23.19.6836-6848.2003&volume=23&pages=6836-6848&publication_year=2003&author=Liao%2CY&author=Hung%2CMC generate?
• How much revenue does https://doi.org/10.1073%2Fpnas.060025397 bring in?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10759547 pull in?
• How much profit does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC18221 make?
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Beta-catenin%2C%20a%20novel%20prognostic%20marker%20for%20breast%20cancer%3A%20its%20roles%20in%20cyclin%20D1%20expression%20and%20cancer%20progression&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.060025397&volume=97&pages=4262-4266&publication_year=2000&author=Lin%2CSY&author=Xia%2CW&author=Wang%2CJC&author=Kwong%2CKY&author=Spohn%2CB&author=Wen%2CY
• Learn about the earnings of https://doi.org/10.1002%2Fmc.20216
• Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16652378
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=Targeting%20carcinogenesis%3A%20a%20role%20for%20the%20prolyl%20isomerase%20Pin1%3F&journal=Mol%20Carcinog&doi=10.1002%2Fmc.20216&volume=45&pages=397-402&publication_year=2006&author=Lu%2CKP&author=Suizu%2CF&author=Zhou%2CXZ&author=Finn%2CG&author=Lam%2CP&author=Wulf%2CG have monthly?
• How much money does https://doi.org/10.1038%2Fnrm2261 make?
• Discover the revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17878917
• What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=The%20prolyl%20isomerase%20PIN1%3A%20a%20pivotal%20new%20twist%20in%20phosphorylation%20signalling%20and%20disease&journal=Nat%20Rev%20Mol%20Cell%20Biol&doi=10.1038%2Fnrm2261&volume=8&pages=904-916&publication_year=2007&author=Lu%2CKP&author=Zhou%2CXZ?
• Learn how profitable https://doi.org/10.1126%2Fscience.283.5406.1325 is on a monthly basis
• How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10037602 make?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Function%20of%20WW%20domains%20as%20phosphoserine-%20or%20phosphothreonine-binding%20modules&journal=Science&doi=10.1126%2Fscience.283.5406.1325&volume=283&pages=1325-1328&publication_year=1999&author=Lu%2CPJ&author=Zhou%2CXZ&author=Shen%2CM&author=Lu%2CKP?
• Get to know https://doi.org/10.1016%2FS1535-6108%2803%2900248-4's earnings
• What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14585353?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Targeting%20the%20PI3K-Akt%20pathway%20in%20human%20cancer%3A%20rationale%20and%20promise&journal=Cancer%20Cell&doi=10.1016%2FS1535-6108%2803%2900248-4&volume=4&pages=257-262&publication_year=2003&author=Luo%2CJ&author=Manning%2CBD&author=Cantley%2CLC generate?
• What's the financial intake of https://doi.org/10.1016%2Fj.cell.2007.06.009?
• Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17604717
• What's the income of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756685?
• What's the financial intake of http://scholar.google.com/scholar_lookup?&title=AKT%2FPKB%20signaling%3A%20navigating%20downstream&journal=Cell&doi=10.1016%2Fj.cell.2007.06.009&volume=129&pages=1261-1274&publication_year=2007&author=Manning%2CBD&author=Cantley%2CLC?
• What are the earnings of https://doi.org/10.1158%2F0008-5472.CAN-06-3782?
• How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17210696 generate?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Akt1%20ablation%20inhibits%2C%20whereas%20Akt2%20ablation%20accelerates%2C%20the%20development%20of%20mammary%20adenocarcinomas%20in%20mouse%20mammary%20tumor%20virus%20%28MMTV%29-ErbB2%2Fneu%20and%20MMTV-polyoma%20middle%20T%20transgenic%20mice&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-06-3782&volume=67&pages=167-177&publication_year=2007&author=Maroulakou%2CIG&author=Oemler%2CW&author=Naber%2CSP&author=Tsichlis%2CPN generate?
• What's the total monthly financial gain of https://doi.org/10.1074%2Fjbc.273.45.29864?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9792703 pull in?
• Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Cyclin%20D%20expression%20is%20controlled%20post-transcriptionally%20via%20a%20phosphatidylinositol%203-kinase%2FAkt-dependent%20pathway&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.273.45.29864&volume=273&pages=29864-29872&publication_year=1998&author=Muise-Helmericks%2CR&author=Grimes%2CHL&author=Bellacosa%2CA&author=Malstrom%2CSE&author=Tsichlis%2CPN
• Check the income stats for https://doi.org/10.1042%2Fbj20021626
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12495431 net monthly?
• What is the monthly revenue of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223206?
• Financial intake of http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20ABC%20kinases%20by%20phosphorylation%3A%20protein%20kinase%20C%20as%20a%20paradigm&journal=Biochem%20J&doi=10.1042%2Fbj20021626&volume=370&pages=361-371&publication_year=2003&author=Newton%2CAC
• What's https://doi.org/10.1126%2Fscience.1106148's gross income?
• Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15718470
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Phosphorylation%20and%20regulation%20of%20Akt%2FPKB%20by%20the%20rictor-mTOR%20complex&journal=Science&doi=10.1126%2Fscience.1106148&volume=307&pages=1098-1101&publication_year=2005&author=Sarbassov%2CDD&author=Guertin%2CDA&author=Ali%2CSM&author=Sabatini%2CDM?
• What's the total monthly financial gain of https://doi.org/10.1159%2F000096289?
• Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17047397
• How much income is http://scholar.google.com/scholar_lookup?&title=Mutational%20analysis%20of%20AKT1%2C%20AKT2%20and%20AKT3%20genes%20in%20common%20human%20carcinomas&journal=Oncology&doi=10.1159%2F000096289&volume=70&pages=285-289&publication_year=2006&author=Soung%2CYH&author=Lee%2CJW&author=Nam%2CSW&author=Lee%2CJY&author=Yoo%2CNJ&author=Lee%2CSH earning monthly?
• Get to know https://link.springer.com/doi/10.1007/s00018-007-7270-0's earnings
• Income figures for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17965833
• How much income is http://scholar.google.com/scholar_lookup?&title=Prolyl%20isomerase%2C%20Pin1%3A%20new%20findings%20of%20post-translational%20modifications%20and%20physiological%20substrates%20in%20cancer%2C%20asthma%20and%20Alzheimer%2Fs%20disease&journal=Cell%20Mol%20Life%20Sci&doi=10.1007%2Fs00018-007-7270-0&volume=65&pages=359-375&publication_year=2008&author=Takahashi%2CK&author=Uchida%2CC&author=Shin%2CRW&author=Shimazaki%2CK&author=Uchida%2CT earning monthly?
• How much profit does https://doi.org/10.1038%2Fsj.onc.1209100 generate?
• How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16288285?
• How much money does http://scholar.google.com/scholar_lookup?&title=AKT%20signaling%20in%20normal%20and%20malignant%20cells&journal=Oncogene&doi=10.1038%2Fsj.onc.1209100&volume=24&pages=7391-7393&publication_year=2005&author=Testa%2CJR&author=Tsichlis%2CPN generate?
• How much does https://doi.org/10.2174%2F156800908783497140 generate monthly?
• How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18288941 make?
• How much does http://scholar.google.com/scholar_lookup?&title=Deregulation%20of%20the%20Akt%20pathway%20in%20human%20cancer&journal=Curr%20Cancer%20Drug%20Targets&doi=10.2174%2F156800908783497140&volume=8&pages=27-36&publication_year=2008&author=Tokunaga%2CE&author=Oki%2CE&author=Egashira%2CA&author=Sadanaga%2CN&author=Morita%2CM&author=Kakeji%2CY generate monthly?
• How much does https://doi.org/10.1038%2Fsj.emboj.7600323 net monthly?
• Get to know http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15257284's earnings
• What are the total earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514501?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Modeling%20breast%20cancer%20in%20vivo%20and%20ex%20vivo%20reveals%20an%20essential%20role%20of%20Pin1%20in%20tumorigenesis&journal=EMBO%20J&doi=10.1038%2Fsj.emboj.7600323&volume=23&pages=3397-3407&publication_year=2004&author=Wulf%2CG&author=Garg%2CP&author=Liou%2CYC&author=Iglehart%2CD&author=Lu%2CKP bring in?
• What's the financial intake of https://doi.org/10.1158%2F1078-0432.CCR-03-0527?
• Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15173090
• http://scholar.google.com/scholar_lookup?&title=Phosphorylation%2Fcytoplasmic%20localization%20of%20p21Cip1%2FWAF1%20is%20associated%20with%20HER2%2Fneu%20overexpression%20and%20provides%20a%20novel%20combination%20predictor%20for%20poor%20prognosis%20in%20breast%20cancer%20patients&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-03-0527&volume=10&pages=3815-3824&publication_year=2004&author=Xia%2CW&author=Chen%2CJS&author=Zhou%2CX&author=Sun%2CPR&author=Lee%2CDF&author=Liao%2CY income
• How much does https://doi.org/10.1042%2Fbst0320350 make?
• How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15046607 make?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Physiological%20functions%20of%20protein%20kinase%20B%2FAkt&journal=Biochem%20Soc%20Trans&doi=10.1042%2Fbst0320350&volume=32&pages=350-354&publication_year=2004&author=Yang%2CZZ&author=Tschopp%2CO&author=Baudry%2CA&author=Dummler%2CB&author=Hynx%2CD&author=Hemmings%2CBA bring in?
• How much does https://doi.org/10.1038%2Fncb1110 net monthly?
• Find out how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15048125 earns monthly
• Profit of http://scholar.google.com/scholar_lookup?&title=A%20signalling%20pathway%20controlling%20c-Myc%20degradation%20that%20impacts%20oncogenic%20transformation%20of%20human%20cells&journal=Nat%20Cell%20Biol&doi=10.1038%2Fncb1110&volume=6&pages=308-318&publication_year=2004&author=Yeh%2CE&author=Cunningham%2CM&author=Arnold%2CH&author=Chasse%2CD&author=Monteith%2CT&author=Ivaldi%2CG
• How much income does https://doi.org/10.1038%2Fnrc2107 have?
• What's the income generated by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17410202 each month?
• How much does http://scholar.google.com/scholar_lookup?&title=PIN1%2C%20the%20cell%20cycle%20and%20cancer&journal=Nat%20Rev%20Cancer&doi=10.1038%2Fnrc2107&volume=7&pages=381-388&publication_year=2007&author=Yeh%2CES&author=Means%2CAR net monthly?
• How much profit does https://doi.org/10.1038%2Fnature01120 generate?
• Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12397362
• Profit of http://scholar.google.com/scholar_lookup?&title=The%20prolyl%20isomerase%20Pin1%20reveals%20a%20mechanism%20to%20control%20p53%20functions%20after%20genotoxic%20insults&journal=Nature&doi=10.1038%2Fnature01120&volume=419&pages=853-857&publication_year=2002&author=Zacchi%2CP&author=Gostissa%2CM&author=Uchida%2CT&author=Salvagno%2CC&author=Avolio%2CF&author=Volinia%2CS
• Get to know https://citation-needed.springer.com/v2/references/10.1038/onc.2009.98?format=refman&flavour=references's earnings
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Y%20Liao earn?
• Income figures for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Y%20Liao%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Y%20Wei earn?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Y%20Wei%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=X%20Zhou income
• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22X%20Zhou%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
• How much income does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=J%20-Y%20Yang have?
• What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22J%20-Y%20Yang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=C%20Dai?
• What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22C%20Dai%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Y%20-J%20Chen?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Y%20-J%20Chen%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=N%20K%20Agarwal pull in?
• Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22N%20K%20Agarwal%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• See how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=D%20Sarbassov makes per month
• How much cash flow does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22D%20Sarbassov%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have monthly?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=D%20Shi gross monthly?
• How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22D%20Shi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=D%20Yu's revenue stream
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22D%20Yu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's revenue stream
• What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=M%20-C%20Hung?
• Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22M%20-C%20Hung%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What's the financial outcome of https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_BFonc200998_MOESM11_ESM.jpg?
• Find out how much https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_BFonc200998_MOESM12_ESM.jpg earns monthly
• Learn about the earnings of https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_BFonc200998_MOESM13_ESM.jpg
• What are the total earnings of https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_BFonc200998_MOESM14_ESM.jpg?
• What's https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2009.98/MediaObjects/41388_2009_BFonc200998_MOESM15_ESM.jpg's gross income?
• What's the financial intake of https://s100.copyright.com/AppDispatchServlet?title=Peptidyl-prolyl%20cis%2Ftrans%20isomerase%20Pin1%20is%20critical%20for%20the%20regulation%20of%20PKB%2FAkt%20stability%20and%20activation%20phosphorylation&author=Y%20Liao%20et%20al&contentID=10.1038%2Fonc.2009.98©right=Macmillan%20Publishers%20Limited&publication=0950-9232&publicationDate=2009-05-18&publisherName=SpringerNature&orderBeanReset=true?
• How much profit does https://citation-needed.springer.com/v2/references/10.1038/onc.2009.98?format=refman&flavour=citation make?
• How much revenue does https://doi.org/10.1186/s13045-021-01137-8 generate?
• How much does https://doi.org/10.1038/s41598-021-88478-z net monthly?
• How much does https://doi.org/10.1186/s13045-018-0611-7 rake in every month?
• What's the profit of https://doi.org/10.1038/s41467-018-05402-2?
• What's the monthly income of https://doi.org/10.1038/srep43639?
• Find out how much https://www.protocols.io/ earns monthly
• Check the income stats for https://www.natureindex.com/
• How much does http://www.naturechina.com generate monthly?
• How much profit does https://www.natureasia.com/ja-jp generate?

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref