Here's how NATURE.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

NATURE . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Questions
  10. Schema
  11. Social Networks
  12. External Links
  13. Analytics And Tracking
  14. Libraries
  15. Hosting Providers
  16. CDN Services

We are analyzing https://www.nature.com/articles/onc20086.

Title:
MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer | Oncogene
Description:
To define novel pathways that regulate susceptibility to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) in non-small cell lung cancer (NSCLC), we have performed genome-wide expression profiling of microRNAs (miRs). We show that in TRAIL-resistant NSCLC cells, levels of different miRs are increased, and in particular, miR-221 and -222. We demonstrate that these miRs impair TRAIL-dependent apoptosis by inhibiting the expression of key functional proteins. Indeed, transfection with anti-miR-221 and -222 rendered CALU-1-resistant cells sensitive to TRAIL. Conversely, H460-sensitive cells treated with -221 and -222 pre-miRs become resistant to TRAIL. miR-221 and -222 target the 3′-UTR of Kit and p27kip1 mRNAs, but interfere with TRAIL signaling mainly through p27kip1. In conclusion, we show that high expression levels of miR-221 and -222 are needed to maintain the TRAIL-resistant phenotype, thus making these miRs as promising therapeutic targets or diagnostic tool for TRAIL resistance in NSCLC.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Education
  • Science
  • Telecommunications

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,555,829 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$536,300 per month
Estimations show Nature.com's display ad online revenue falls between $357,511 and $983,155 per month.

Keywords {🔍}

article, google, scholar, cas, cancer, cell, nature, microrna, human, expression, apoptosis, trail, access, oncogene, lung, micrornas, pkip, content, resistance, cells, res, cookies, published, nonsmall, garofalo, condorelli, tumor, usa, privacy, quintavalle, romano, open, proc, natl, acad, sci, biol, protein, walczak, naples, data, february, signatures, leva, zanca, nsclc, mirs, levels, role, nat,

Topics {✒️}

nature portfolio permissions reprints privacy policy nature 432 nature advertising cancer development social media related apoptosis-inducing ligand author information authors p27 cell-cycle inhibitors micro-rna genes mir15 h460-sensitive cells treated author correspondence genome-wide microrna profiling circulating mir-22-3p levels tumor necrosis factor chronic lymphocytic leukemia personal data springerlink instant access trail-induced apoptosis pathway data protection permissions trail-resistant nsclc cells neural cell specification mir-222 expression affects erythroleukemic cell growth decreased cell proliferation privacy human dendritic cells european economic area issue learn papillary thyroid carcinoma calin ga increased p27kip1 expression molecular biology high expression levels caspase-induced proteolysis tumor suppressor gene genome-scale microrna human neuronal differentiation cyclin-cdk activity van de craen explore content subscription content comprehensive cancer center ohio state university trail-induced apoptosis key functional proteins promising therapeutic targets

Questions {❓}

  • New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer
         description:To define novel pathways that regulate susceptibility to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) in non-small cell lung cancer (NSCLC), we have performed genome-wide expression profiling of microRNAs (miRs). We show that in TRAIL-resistant NSCLC cells, levels of different miRs are increased, and in particular, miR-221 and -222. We demonstrate that these miRs impair TRAIL-dependent apoptosis by inhibiting the expression of key functional proteins. Indeed, transfection with anti-miR-221 and -222 rendered CALU-1-resistant cells sensitive to TRAIL. Conversely, H460-sensitive cells treated with -221 and -222 pre-miRs become resistant to TRAIL. miR-221 and -222 target the 3′-UTR of Kit and p27kip1 mRNAs, but interfere with TRAIL signaling mainly through p27kip1. In conclusion, we show that high expression levels of miR-221 and -222 are needed to maintain the TRAIL-resistant phenotype, thus making these miRs as promising therapeutic targets or diagnostic tool for TRAIL resistance in NSCLC.
         datePublished:2008-02-04T00:00:00Z
         dateModified:2024-02-28T00:00:00Z
         pageStart:3845
         pageEnd:3855
         sameAs:https://doi.org/10.1038/onc.2008.6
         keywords:
            microRNA
            non-small cell lung cancer
            apoptosis
            Medicine/Public Health
            general
            Internal Medicine
            Cell Biology
            Human Genetics
            Oncology
            Apoptosis
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig5_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig6_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig7_HTML.jpg
         isPartOf:
            name:Oncogene
            issn:
               1476-5594
               0950-9232
            volumeNumber:27
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:M Garofalo
               affiliation:
                     name:University of Naples Federico II
                     address:
                        name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
                        type:PostalAddress
                     type:Organization
                     name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
                     address:
                        name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
                        type:PostalAddress
                     type:Organization
                     name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
                     address:
                        name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:C Quintavalle
               affiliation:
                     name:University of Naples Federico II
                     address:
                        name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
                        type:PostalAddress
                     type:Organization
                     name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
                     address:
                        name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
                        type:PostalAddress
                     type:Organization
               type:Person
               name:G Di Leva
               affiliation:
                     name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
                     address:
                        name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:C Zanca
               affiliation:
                     name:University of Naples Federico II
                     address:
                        name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
                        type:PostalAddress
                     type:Organization
                     name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
                     address:
                        name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
                        type:PostalAddress
                     type:Organization
               type:Person
               name:G Romano
               affiliation:
                     name:University of Naples Federico II
                     address:
                        name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
                        type:PostalAddress
                     type:Organization
                     name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
                     address:
                        name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
                        type:PostalAddress
                     type:Organization
               type:Person
               name:C Taccioli
               affiliation:
                     name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
                     address:
                        name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:C G Liu
               affiliation:
                     name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
                     address:
                        name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:C M Croce
               affiliation:
                     name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
                     address:
                        name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:G Condorelli
               affiliation:
                     name:University of Naples Federico II
                     address:
                        name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
                        type:PostalAddress
                     type:Organization
                     name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
                     address:
                        name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
                        type:PostalAddress
                     type:Organization
                     name:Facoltà di Scienze Biotecnologiche, University of Naples Federico II
                     address:
                        name:Facoltà di Scienze Biotecnologiche, University of Naples Federico II, Naples, Italy
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer
      description:To define novel pathways that regulate susceptibility to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) in non-small cell lung cancer (NSCLC), we have performed genome-wide expression profiling of microRNAs (miRs). We show that in TRAIL-resistant NSCLC cells, levels of different miRs are increased, and in particular, miR-221 and -222. We demonstrate that these miRs impair TRAIL-dependent apoptosis by inhibiting the expression of key functional proteins. Indeed, transfection with anti-miR-221 and -222 rendered CALU-1-resistant cells sensitive to TRAIL. Conversely, H460-sensitive cells treated with -221 and -222 pre-miRs become resistant to TRAIL. miR-221 and -222 target the 3′-UTR of Kit and p27kip1 mRNAs, but interfere with TRAIL signaling mainly through p27kip1. In conclusion, we show that high expression levels of miR-221 and -222 are needed to maintain the TRAIL-resistant phenotype, thus making these miRs as promising therapeutic targets or diagnostic tool for TRAIL resistance in NSCLC.
      datePublished:2008-02-04T00:00:00Z
      dateModified:2024-02-28T00:00:00Z
      pageStart:3845
      pageEnd:3855
      sameAs:https://doi.org/10.1038/onc.2008.6
      keywords:
         microRNA
         non-small cell lung cancer
         apoptosis
         Medicine/Public Health
         general
         Internal Medicine
         Cell Biology
         Human Genetics
         Oncology
         Apoptosis
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig5_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig6_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2008.6/MediaObjects/41388_2008_Article_BFonc20086_Fig7_HTML.jpg
      isPartOf:
         name:Oncogene
         issn:
            1476-5594
            0950-9232
         volumeNumber:27
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:M Garofalo
            affiliation:
                  name:University of Naples Federico II
                  address:
                     name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
                     type:PostalAddress
                  type:Organization
                  name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
                  address:
                     name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
                     type:PostalAddress
                  type:Organization
                  name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
                  address:
                     name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:C Quintavalle
            affiliation:
                  name:University of Naples Federico II
                  address:
                     name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
                     type:PostalAddress
                  type:Organization
                  name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
                  address:
                     name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:G Di Leva
            affiliation:
                  name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
                  address:
                     name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:C Zanca
            affiliation:
                  name:University of Naples Federico II
                  address:
                     name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
                     type:PostalAddress
                  type:Organization
                  name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
                  address:
                     name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:G Romano
            affiliation:
                  name:University of Naples Federico II
                  address:
                     name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
                     type:PostalAddress
                  type:Organization
                  name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
                  address:
                     name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:C Taccioli
            affiliation:
                  name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
                  address:
                     name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:C G Liu
            affiliation:
                  name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
                  address:
                     name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:C M Croce
            affiliation:
                  name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
                  address:
                     name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:G Condorelli
            affiliation:
                  name:University of Naples Federico II
                  address:
                     name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
                     type:PostalAddress
                  type:Organization
                  name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
                  address:
                     name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
                     type:PostalAddress
                  type:Organization
                  name:Facoltà di Scienze Biotecnologiche, University of Naples Federico II
                  address:
                     name:Facoltà di Scienze Biotecnologiche, University of Naples Federico II, Naples, Italy
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Oncogene
      issn:
         1476-5594
         0950-9232
      volumeNumber:27
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Naples Federico II
      address:
         name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
         type:PostalAddress
      name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
      address:
         name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
         type:PostalAddress
      name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
      address:
         name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
         type:PostalAddress
      name:University of Naples Federico II
      address:
         name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
         type:PostalAddress
      name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
      address:
         name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
         type:PostalAddress
      name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
      address:
         name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
         type:PostalAddress
      name:University of Naples Federico II
      address:
         name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
         type:PostalAddress
      name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
      address:
         name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
         type:PostalAddress
      name:University of Naples Federico II
      address:
         name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
         type:PostalAddress
      name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
      address:
         name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
         type:PostalAddress
      name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
      address:
         name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
         type:PostalAddress
      name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
      address:
         name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
         type:PostalAddress
      name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
      address:
         name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
         type:PostalAddress
      name:University of Naples Federico II
      address:
         name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
         type:PostalAddress
      name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
      address:
         name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
         type:PostalAddress
      name:Facoltà di Scienze Biotecnologiche, University of Naples Federico II
      address:
         name:Facoltà di Scienze Biotecnologiche, University of Naples Federico II, Naples, Italy
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:M Garofalo
      affiliation:
            name:University of Naples Federico II
            address:
               name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
               type:PostalAddress
            type:Organization
            name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
            address:
               name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
               type:PostalAddress
            type:Organization
            name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
            address:
               name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
               type:PostalAddress
            type:Organization
      name:C Quintavalle
      affiliation:
            name:University of Naples Federico II
            address:
               name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
               type:PostalAddress
            type:Organization
            name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
            address:
               name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
               type:PostalAddress
            type:Organization
      name:G Di Leva
      affiliation:
            name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
            address:
               name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
               type:PostalAddress
            type:Organization
      name:C Zanca
      affiliation:
            name:University of Naples Federico II
            address:
               name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
               type:PostalAddress
            type:Organization
            name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
            address:
               name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
               type:PostalAddress
            type:Organization
      name:G Romano
      affiliation:
            name:University of Naples Federico II
            address:
               name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
               type:PostalAddress
            type:Organization
            name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
            address:
               name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
               type:PostalAddress
            type:Organization
      name:C Taccioli
      affiliation:
            name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
            address:
               name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
               type:PostalAddress
            type:Organization
      name:C G Liu
      affiliation:
            name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
            address:
               name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
               type:PostalAddress
            type:Organization
      name:C M Croce
      affiliation:
            name:Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University
            address:
               name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
               type:PostalAddress
            type:Organization
      name:G Condorelli
      affiliation:
            name:University of Naples Federico II
            address:
               name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
               type:PostalAddress
            type:Organization
            name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS
            address:
               name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
               type:PostalAddress
            type:Organization
            name:Facoltà di Scienze Biotecnologiche, University of Naples Federico II
            address:
               name:Facoltà di Scienze Biotecnologiche, University of Naples Federico II, Naples, Italy
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
      name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
      name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
      name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
      name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
      name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
      name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
      name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
      name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
      name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
      name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
      name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
      name:Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
      name:Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy
      name:Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, IEOS, Naples, Italy
      name:Facoltà di Scienze Biotecnologiche, University of Naples Federico II, Naples, Italy
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(1)

External Links {🔗}(110)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Prism.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
  • mxb-002c5801.gslb.pphosted.com

Name Servers:

  • pdns1.ultradns.net
  • pdns2.ultradns.net
  • pdns3.ultradns.org
  • pdns4.ultradns.org
  • pdns5.ultradns.info
  • pdns6.ultradns.co.uk

CDN Services {📦}

  • Crossref

4.64s.