NATURE . COM {}

Matching Content Categories {📚}

• Education
• Science
• Animals & Wildlife

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$63,100 per month
Our analysis indicates Nature.com generates between $42,042 and $115,616 monthly online from display ads.

Keywords {🔍}

article, google, scholar, cas, rna, nature, methylation, trna, dnmt, access, dna, cell, nsun, nucleic, acids, res, content, nat, methyltransferase, mol, biol, cookies, lyko, mouse, genet, research, privacy, molecular, biology, protein, schaefer, helm, modification, open, gene, epigenetics, genes, dev, stem, analysis, data, information, promotes, synthesis, cytosinec, trnas, cellular, development, motorin, cells,

Topics {✒️}

nature portfolio permissions reprints privacy policy stem cell research ovarian research nature advertising social media author information authors italy mediates myc-induced proliferation opioid-induced reward-seeking multisite-specific trna cytosine-c5 trna methylation manage preferences author correspondence trna-derived small rnas long-term opioid withdrawal springerlink instant access trna biology charges m5c methyltransferase rlmi personal data mrna-expression profiling data protection permissions gene expression cytosine-c5 methylation retina development rna cytosine methylation double mutants showed matthias schaefer trna methylation analysis codon-biased translation frank lyko dna methylation landscapes rna nucleotide methylation m5c-methyltransferase steady-state levels privacy embryonic stem cells stefanie kellner stress-induced cleavage reveals evolutionary links rna modification enzymes development competing financial interests dna methyltransferase homologue rna–methyltransferase misu rna methyltransferase misu molecular mechanisms

Questions {❓}

• Do all modifications benefit all tRNAs?
• Grand challenge commentary: RNA epigenetics?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis
         description:Although cytosine-C5 methylation is a prominent modification of tRNAs, its functional significance has been unclear. Mice that lack both the Dnmt2 and NSun2 tRNA methyltransferases showed developmental and cellular differentiation defects, and loss of Dnmt2 and NSun2 was further associated with tRNA degradation and reduced rates of protein synthesis, suggesting that this modification promotes mouse development by supporting protein synthesis. The function of cytosine-C5 methylation, a widespread modification of tRNAs, has remained obscure, particularly in mammals. We have now developed a mouse strain defective in cytosine-C5 tRNA methylation, by disrupting both the Dnmt2 and the NSun2 tRNA methyltransferases. Although the lack of either enzyme alone has no detectable effects on mouse viability, double mutants showed a synthetic lethal interaction, with an underdeveloped phenotype and impaired cellular differentiation. tRNA methylation analysis of the double-knockout mice demonstrated complementary target-site specificities for Dnmt2 and NSun2 and a complete loss of cytosine-C5 tRNA methylation. Steady-state levels of unmethylated tRNAs were substantially reduced, and loss of Dnmt2 and NSun2 was further associated with reduced rates of overall protein synthesis. These results establish a biologically important function for cytosine-C5 tRNA methylation in mammals and suggest that this modification promotes mouse development by supporting protein synthesis.
         datePublished:2012-08-12T00:00:00Z
         dateModified:2012-08-12T00:00:00Z
         pageStart:900
         pageEnd:905
         sameAs:https://doi.org/10.1038/nsmb.2357
         keywords:
            Epigenetics
            RNA modification
            tRNAs
            Life Sciences
            general
            Biochemistry
            Protein Structure
            Membrane Biology
            Biological Microscopy
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig5_HTML.jpg
         isPartOf:
            name:Nature Structural & Molecular Biology
            issn:
               1545-9985
               1545-9993
            volumeNumber:19
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Francesca Tuorto
               affiliation:
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Reinhard Liebers
               affiliation:
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Tanja Musch
               affiliation:
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Matthias Schaefer
               affiliation:
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Sarah Hofmann
               affiliation:
                     name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
                     address:
                        name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Stefanie Kellner
               affiliation:
                     name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
                     address:
                        name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Michaela Frye
               affiliation:
                     name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge
                     address:
                        name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mark Helm
               affiliation:
                     name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
                     address:
                        name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Georg Stoecklin
               affiliation:
                     name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
                     address:
                        name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Frank Lyko
               affiliation:
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis
      description:Although cytosine-C5 methylation is a prominent modification of tRNAs, its functional significance has been unclear. Mice that lack both the Dnmt2 and NSun2 tRNA methyltransferases showed developmental and cellular differentiation defects, and loss of Dnmt2 and NSun2 was further associated with tRNA degradation and reduced rates of protein synthesis, suggesting that this modification promotes mouse development by supporting protein synthesis. The function of cytosine-C5 methylation, a widespread modification of tRNAs, has remained obscure, particularly in mammals. We have now developed a mouse strain defective in cytosine-C5 tRNA methylation, by disrupting both the Dnmt2 and the NSun2 tRNA methyltransferases. Although the lack of either enzyme alone has no detectable effects on mouse viability, double mutants showed a synthetic lethal interaction, with an underdeveloped phenotype and impaired cellular differentiation. tRNA methylation analysis of the double-knockout mice demonstrated complementary target-site specificities for Dnmt2 and NSun2 and a complete loss of cytosine-C5 tRNA methylation. Steady-state levels of unmethylated tRNAs were substantially reduced, and loss of Dnmt2 and NSun2 was further associated with reduced rates of overall protein synthesis. These results establish a biologically important function for cytosine-C5 tRNA methylation in mammals and suggest that this modification promotes mouse development by supporting protein synthesis.
      datePublished:2012-08-12T00:00:00Z
      dateModified:2012-08-12T00:00:00Z
      pageStart:900
      pageEnd:905
      sameAs:https://doi.org/10.1038/nsmb.2357
      keywords:
         Epigenetics
         RNA modification
         tRNAs
         Life Sciences
         general
         Biochemistry
         Protein Structure
         Membrane Biology
         Biological Microscopy
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig5_HTML.jpg
      isPartOf:
         name:Nature Structural & Molecular Biology
         issn:
            1545-9985
            1545-9993
         volumeNumber:19
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Francesca Tuorto
            affiliation:
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Reinhard Liebers
            affiliation:
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Tanja Musch
            affiliation:
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Matthias Schaefer
            affiliation:
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Sarah Hofmann
            affiliation:
                  name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
                  address:
                     name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Stefanie Kellner
            affiliation:
                  name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
                  address:
                     name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Michaela Frye
            affiliation:
                  name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge
                  address:
                     name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mark Helm
            affiliation:
                  name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
                  address:
                     name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Georg Stoecklin
            affiliation:
                  name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
                  address:
                     name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Frank Lyko
            affiliation:
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Structural & Molecular Biology
      issn:
         1545-9985
         1545-9993
      volumeNumber:19
Organization:
      name:Nature Publishing Group US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Deutsches Krebsforschungszentrum
      address:
         name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Deutsches Krebsforschungszentrum
      address:
         name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Deutsches Krebsforschungszentrum
      address:
         name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Deutsches Krebsforschungszentrum
      address:
         name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
      address:
         name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
      address:
         name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
         type:PostalAddress
      name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge
      address:
         name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK
         type:PostalAddress
      name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
      address:
         name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
         type:PostalAddress
      name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
      address:
         name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Deutsches Krebsforschungszentrum
      address:
         name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Francesca Tuorto
      affiliation:
            name:Deutsches Krebsforschungszentrum
            address:
               name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Reinhard Liebers
      affiliation:
            name:Deutsches Krebsforschungszentrum
            address:
               name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Tanja Musch
      affiliation:
            name:Deutsches Krebsforschungszentrum
            address:
               name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Matthias Schaefer
      affiliation:
            name:Deutsches Krebsforschungszentrum
            address:
               name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Sarah Hofmann
      affiliation:
            name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
            address:
               name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Stefanie Kellner
      affiliation:
            name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
            address:
               name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
               type:PostalAddress
            type:Organization
      name:Michaela Frye
      affiliation:
            name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge
            address:
               name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK
               type:PostalAddress
            type:Organization
      name:Mark Helm
      affiliation:
            name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
            address:
               name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
               type:PostalAddress
            type:Organization
      name:Georg Stoecklin
      affiliation:
            name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
            address:
               name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Frank Lyko
      affiliation:
            name:Deutsches Krebsforschungszentrum
            address:
               name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
      name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK
      name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
      name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(1)

• https://twitter.com/NatureSMB

External Links {🔗}(109)

• How much does https://link.springer.com/article/10.1038/nsmb.2357?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle bring in each month?
• How much revenue does http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE36918 generate?
• How much income is https://doi.org/10.1038%2Fnrg2341 earning monthly?
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=DNA%20methylation%20landscapes%3A%20provocative%20insights%20from%20epigenomics&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2341&volume=9&pages=465-476&publication_year=2008&author=Suzuki%2CMM&author=Bird%2CA
• What is the earnings of https://doi.org/10.1016%2Fj.tig.2008.12.005?
• What's the income generated by http://scholar.google.com/scholar_lookup?&title=Genetics%20and%20epigenetics%3A%20stability%20and%20plasticity%20during%20cellular%20differentiation&journal=Trends%20Genet.&doi=10.1016%2Fj.tig.2008.12.005&volume=25&pages=129-136&publication_year=2009&author=Mohn%2CF&author=Schubeler%2CD each month?
• How much money does https://doi.org/10.1038%2Fnrg3230 make?
• How much income is http://scholar.google.com/scholar_lookup?&title=Functions%20of%20DNA%20methylation%3A%20islands%2C%20start%20sites%2C%20gene%20bodies%20and%20beyond&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg3230&volume=13&pages=484-492&publication_year=2012&author=Jones%2CPA earning monthly?
• Explore the financials of https://doi.org/10.1101%2Fgad.1956510
• http://scholar.google.com/scholar_lookup?&title=tRNA%20biology%20charges%20to%20the%20front&journal=Genes%20Dev.&doi=10.1101%2Fgad.1956510&volume=24&pages=1832-1860&publication_year=2010&author=Phizicky%2CEM&author=Hopper%2CAK's financial summary
• How much cash flow does https://doi.org/10.1093%2Fnar%2Fgkp1117 have monthly?
• Explore the financials of http://scholar.google.com/scholar_lookup?&title=5-methylcytosine%20in%20RNA%3A%20detection%2C%20enzymatic%20formation%20and%20biological%20functions&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgkp1117&volume=38&pages=1415-1430&publication_year=2010&author=Motorin%2CY&author=Lyko%2CF&author=Helm%2CM
• How much cash flow does https://doi.org/10.1126%2Fscience.1120976 have monthly?
• Get to know http://scholar.google.com/scholar_lookup?&title=Methylation%20of%20tRNAAsp%20by%20the%20DNA%20methyltransferase%20homolog%20Dnmt2&journal=Science&doi=10.1126%2Fscience.1120976&volume=311&pages=395-398&publication_year=2006&author=Goll%2CMG's earnings
• Financial intake of https://doi.org/10.1101%2Fgad.586710
• How much revenue does http://scholar.google.com/scholar_lookup?&title=RNA%20methylation%20by%20Dnmt2%20protects%20transfer%20RNAs%20against%20stress-induced%20cleavage&journal=Genes%20Dev.&doi=10.1101%2Fgad.586710&volume=24&pages=1590-1595&publication_year=2010&author=Schaefer%2CM generate?
• How much money does https://doi.org/10.1093%2Fnar%2F23.2.203 make?
• What's the financial gain of http://scholar.google.com/scholar_lookup?&title=The%20fission%20yeast%20gene%20pmt1%2B%20encodes%20a%20DNA%20methyltransferase%20homologue&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F23.2.203&volume=23&pages=203-210&publication_year=1995&author=Wilkinson%2CCR&author=Bartlett%2CR&author=Nurse%2CP&author=Bird%2CAP?
• What's the revenue for https://doi.org/10.1093%2Fhmg%2F7.2.279?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=A%20candidate%20mammalian%20DNA%20methyltransferase%20related%20to%20pmt1p%20of%20fission%20yeast&journal=Hum.%20Mol.%20Genet.&doi=10.1093%2Fhmg%2F7.2.279&volume=7&pages=279-284&publication_year=1998&author=Yoder%2CJA&author=Bestor%2CTH?
• What's https://doi.org/10.1093%2Fnar%2F26.11.2536's gross income?
• What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Dnmt2%20is%20not%20required%20for%20de%20novo%20and%20maintenance%20methylation%20of%20viral%20DNA%20in%20embryonic%20stem%20cells&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F26.11.2536&volume=26&pages=2536-2540&publication_year=1998&author=Okano%2CM&author=Xie%2CS&author=Li%2CE?
• https://doi.org/10.1261%2Frna.970408 income
• How much does http://scholar.google.com/scholar_lookup?&title=Human%20DNMT2%20methylates%20tRNAAsp%20molecules%20using%20a%20DNA%20methyltransferase-like%20catalytic%20mechanism&journal=RNA&doi=10.1261%2Frna.970408&volume=14&pages=1663-1670&publication_year=2008&author=Jurkowski%2CTP rake in every month?
• How much cash flow does https://doi.org/10.1016%2Fj.jmb.2008.08.062 have monthly?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Crystal%20structure%20of%20the%20Escherichia%20coli%2023S%20rRNA%3Am5C%20methyltransferase%20RlmI%20%28YccW%29%20reveals%20evolutionary%20links%20between%20RNA%20modification%20enzymes&journal=J.%20Mol.%20Biol.&doi=10.1016%2Fj.jmb.2008.08.062&volume=383&pages=652-666&publication_year=2008&author=Sunita%2CS generate?
• What's the financial outcome of https://doi.org/10.1016%2FB978-0-12-387685-0.00002-0?
• http://scholar.google.com/scholar_lookup?&title=Natural%20history%20of%20eukaryotic%20DNA%20methylation%20systems&journal=Prog.%20Mol.%20Biol.%20Transl.%20Sci.&doi=10.1016%2FB978-0-12-387685-0.00002-0&volume=101&pages=25-104&publication_year=2011&author=Iyer%2CLM&author=Abhiman%2CS&author=Aravind%2CL's total income per month
• What are the earnings of https://doi.org/10.1371%2Fjournal.pone.0028104?
• Earnings of http://scholar.google.com/scholar_lookup?&title=On%20the%20evolutionary%20origin%20of%20eukaryotic%20DNA%20methyltransferases%20and%20Dnmt2&journal=PLoS%20ONE&doi=10.1371%2Fjournal.pone.0028104&volume=6&publication_year=2011&author=Jurkowski%2CTP&author=Jeltsch%2CA
• What is the earnings of https://link.springer.com/doi/10.1007/s00412-009-0240-6?
• How much does http://scholar.google.com/scholar_lookup?&title=Solving%20the%20Dnmt2%20enigma&journal=Chromosoma.&doi=10.1007%2Fs00412-009-0240-6&volume=119&pages=35-40&publication_year=2010&author=Schaefer%2CM&author=Lyko%2CF pull in?
• Find out how much https://doi.org/10.1093%2Fnar%2Fgkl765 earns monthly
• Earnings of http://scholar.google.com/scholar_lookup?&title=Identification%20of%20human%20tRNA%3Am5C%20methyltransferase%20catalysing%20intron-dependent%20m5C%20formation%20in%20the%20first%20position%20of%20the%20anticodon%20of%20the%20pre-tRNA%20Leu%20%28CAA%29&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgkl765&volume=34&pages=6034-6043&publication_year=2006&author=Brzezicha%2CB
• What's the financial gain of https://doi.org/10.1371%2Fjournal.pgen.1002403?
• http://scholar.google.com/scholar_lookup?&title=The%20RNA%E2%80%93methyltransferase%20Misu%20%28NSun2%29%20poises%20epidermal%20stem%20cells%20to%20differentiate&journal=PLoS%20Genet.&doi=10.1371%2Fjournal.pgen.1002403&volume=7&publication_year=2011&author=Blanco%2CS income
• How much money does https://doi.org/10.1017%2FS1355838299982201 make?
• How much does http://scholar.google.com/scholar_lookup?&title=Multisite-specific%20tRNA%3Am5C-methyltransferase%20%28Trm4%29%20in%20yeast%20Saccharomyces%20cerevisiae%3A%20identification%20of%20the%20gene%20and%20substrate%20specificity%20of%20the%20enzyme&journal=RNA&doi=10.1017%2FS1355838299982201&volume=5&pages=1105-1118&publication_year=1999&author=Motorin%2CY&author=Grosjean%2CH pull in?
• https://doi.org/10.1016%2Fj.cub.2006.04.027 income
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=The%20RNA%20methyltransferase%20Misu%20%28NSun2%29%20mediates%20Myc-induced%20proliferation%20and%20is%20upregulated%20in%20tumors&journal=Curr.%20Biol.&doi=10.1016%2Fj.cub.2006.04.027&volume=16&pages=971-981&publication_year=2006&author=Frye%2CM&author=Watt%2CFM
• https://doi.org/10.1093%2Fnar%2Fgks144 income
• http://scholar.google.com/scholar_lookup?&title=Widespread%20occurrence%20of%205-methylcytosine%20in%20human%20coding%20and%20non-coding%20RNA&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgks144&volume=40&pages=5023-5033&publication_year=2012&author=Squires%2CJE's revenue stream
• What are the total earnings of https://doi.org/10.1038%2Fncomms1692?
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=The%20tRNA%20methyltransferase%20NSun2%20stabilizes%20p16%28INK4%29%20mRNA%20by%20methylating%20the%203%E2%80%B2-untranslated%20region%20of%20p16&journal=Nat%20Commun.&doi=10.1038%2Fncomms1692&volume=3&publication_year=2012&author=Zhang%2CX
• Find out how much https://doi.org/10.1093%2Fnar%2Fgkn954 earns monthly
• http://scholar.google.com/scholar_lookup?&title=RNA%20cytosine%20methylation%20analysis%20by%20bisulfite%20sequencing&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgkn954&volume=37&publication_year=2009&author=Schaefer%2CM&author=Pollex%2CT&author=Hanna%2CK&author=Lyko%2CF's financial summary
• Revenue of https://doi.org/10.1093%2Fnar%2Fgki012
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Compilation%20of%20tRNA%20sequences%20and%20sequences%20of%20tRNA%20genes&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgki012&volume=33&pages=D139-D140&publication_year=2005&author=Sprinzl%2CM&author=Vassilenko%2CKS?
• How much does https://doi.org/10.1002%2Fwrna.79 generate monthly?
• What are the earnings of http://scholar.google.com/scholar_lookup?&title=RNA%20nucleotide%20methylation&journal=Wiley%20Interdiscip.%20Rev.%20RNA&doi=10.1002%2Fwrna.79&volume=2&pages=611-631&publication_year=2011&author=Motorin%2CY&author=Helm%2CM?
• Get to know https://doi.org/10.1016%2Fj.febslet.2009.11.049's earnings
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Do%20all%20modifications%20benefit%20all%20tRNAs%3F&journal=FEBS%20Lett.&doi=10.1016%2Fj.febslet.2009.11.049&volume=584&pages=265-271&publication_year=2010&author=Phizicky%2CEM&author=Alfonzo%2CJD
• How much does https://doi.org/10.1016%2Fj.molcel.2005.10.036 net monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=Rapid%20tRNA%20decay%20can%20result%20from%20lack%20of%20nonessential%20modifications&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2005.10.036&volume=21&pages=87-96&publication_year=2006&author=Alexandrov%2CA gross monthly?
• How much does https://doi.org/10.1101%2Fgad.1654308 rake in every month?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Degradation%20of%20several%20hypomodified%20mature%20tRNA%20species%20in%20Saccharomyces%20cerevisiae%20is%20mediated%20by%20Met22%20and%20the%205%E2%80%B2-3%E2%80%B2%20exonucleases%20Rat1%20and%20Xrn1&journal=Genes%20Dev.&doi=10.1101%2Fgad.1654308&volume=22&pages=1369-1380&publication_year=2008&author=Chernyakov%2CI&author=Whipple%2CJM&author=Kotelawala%2CL&author=Grayhack%2CEJ&author=Phizicky%2CEM bring in?
• How much does https://doi.org/10.1371%2Fjournal.pgen.1001247 pull in?
• How much does http://scholar.google.com/scholar_lookup?&title=A%20quantitative%20systems%20approach%20reveals%20dynamic%20control%20of%20tRNA%20modifications%20during%20cellular%20stress&journal=PLoS%20Genet.&doi=10.1371%2Fjournal.pgen.1001247&volume=6&publication_year=2010&author=Chan%2CCT generate monthly?
• What's the monthly income of https://doi.org/10.1126%2Fscience.1192430?
• What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Dom34%3AHbs1%20promotes%20subunit%20dissociation%20and%20peptidyl-tRNA%20drop-off%20to%20initiate%20no-go%20decay&journal=Science&doi=10.1126%2Fscience.1192430&volume=330&pages=369-372&publication_year=2010&author=Shoemaker%2CCJ&author=Eyler%2CDE&author=Green%2CR?
• How much does https://doi.org/10.1016%2Fj.molcel.2011.06.022 earn?
• How much does http://scholar.google.com/scholar_lookup?&title=Angiogenin-induced%20tRNA%20fragments%20inhibit%20translation%20initiation&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2011.06.022&volume=43&pages=613-623&publication_year=2011&author=Ivanov%2CP&author=Emara%2CMM&author=Villen%2CJ&author=Gygi%2CSP&author=Anderson%2CP generate monthly?
• How much does https://doi.org/10.4161%2Fepi.6.1.13418 pull in?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=The%20DNA%20methyltranferase%20Dnmt2%20participates%20in%20RNA%20processing%20during%20cellular%20stress&journal=Epigenetics&doi=10.4161%2Fepi.6.1.13418&volume=6&pages=103-113&publication_year=2011&author=Thiagarajan%2CD&author=Dev%2CRR&author=Khosla%2CS?
• How much does https://doi.org/10.1038%2Fncomms1938 pull in?
• How much does http://scholar.google.com/scholar_lookup?&title=Reprogramming%20of%20tRNA%20modifications%20controls%20the%20oxidative%20stress%20response%20by%20codon-biased%20translation%20of%20proteins&journal=Nat.%20Commun.&doi=10.1038%2Fncomms1938&volume=3&publication_year=2012&author=Chan%2CCT gross monthly?
• https://doi.org/10.1016%2Fj.stem.2008.03.013's financial summary
• How much does http://scholar.google.com/scholar_lookup?&title=A%20hierarchical%20network%20controls%20protein%20translation%20during%20murine%20embryonic%20stem%20cell%20self-renewal%20and%20differentiation&journal=Cell%20Stem%20Cell&doi=10.1016%2Fj.stem.2008.03.013&volume=2&pages=448-460&publication_year=2008&author=Sampath%2CP make?
• How much does https://doi.org/10.1101%2Fgad.1472907 net monthly?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Dnmt2%20functions%20in%20the%20cytoplasm%20to%20promote%20liver%2C%20brain%2C%20and%20retina%20development%20in%20zebrafish&journal=Genes%20Dev.&doi=10.1101%2Fgad.1472907&volume=21&pages=261-266&publication_year=2007&author=Rai%2CK bring in?
• What's the revenue for https://doi.org/10.1038%2Fnchembio.482?
• How much income is http://scholar.google.com/scholar_lookup?&title=Grand%20challenge%20commentary%3A%20RNA%20epigenetics%3F&journal=Nat.%20Chem.%20Biol.&doi=10.1038%2Fnchembio.482&volume=6&pages=863-865&publication_year=2010&author=He%2CC earning monthly?
• What's the financial outcome of https://doi.org/10.1083%2Fjcb.17.2.299?
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Quantitative%20studies%20of%20the%20growth%20of%20mouse%20embryo%20cells%20in%20culture%20and%20their%20development%20into%20established%20lines&journal=J.%20Cell%20Biol.&doi=10.1083%2Fjcb.17.2.299&volume=17&pages=299-313&publication_year=1963&author=Todaro%2CGJ&author=Green%2CH?
• Profit of https://doi.org/10.1093%2Fnar%2Fgkr449
• What's the income of http://scholar.google.com/scholar_lookup?&title=A%20multifunctional%20bioconjugate%20module%20for%20versatile%20photoaffinity%20labeling%20and%20click%20chemistry%20of%20RNA&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgkr449&volume=39&pages=7348-7360&publication_year=2011&author=Kellner%2CS&author=Seidu-Larry%2CS&author=Burhenne%2CJ&author=Motorin%2CY&author=Helm%2CM?
• What's the total monthly financial gain of https://citation-needed.springer.com/v2/references/10.1038/nsmb.2357?format=refman&flavour=references?
• What's the revenue for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Francesca%20Tuorto?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Francesca%20Tuorto%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
• Get to know what's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Reinhard%20Liebers
• Learn about the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Reinhard%20Liebers%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Tanja%20Musch net monthly?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Tanja%20Musch%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en net monthly?
• What's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Matthias%20Schaefer?
• How much profit is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Matthias%20Schaefer%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en making per month?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Sarah%20Hofmann generate?
• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Sarah%20Hofmann%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
• How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Stefanie%20Kellner earning monthly?
• What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Stefanie%20Kellner%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
• Get to know what's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Michaela%20Frye
• What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Michaela%20Frye%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Get to know https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mark%20Helm's earnings
• What's the total monthly financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mark%20Helm%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the monthly money flow for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Georg%20Stoecklin?
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Georg%20Stoecklin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Frank%20Lyko pull in?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Frank%20Lyko%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en net monthly?
• Learn about the earnings of https://static-content.springer.com/esm/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_BFnsmb2357_MOESM11_ESM.pdf
• How much money does https://s100.copyright.com/AppDispatchServlet?title=RNA%20cytosine%20methylation%20by%20Dnmt2%20and%20NSun2%20promotes%20tRNA%20stability%20and%20protein%20synthesis&author=Francesca%20Tuorto%20et%20al&contentID=10.1038%2Fnsmb.2357©right=Springer%20Nature%20America%2C%20Inc.&publication=1545-9993&publicationDate=2012-08-12&publisherName=SpringerNature&orderBeanReset=true generate?
• Get to know what's the income of https://citation-needed.springer.com/v2/references/10.1038/nsmb.2357?format=refman&flavour=citation
• What's the financial gain of https://doi.org/10.1038/s41388-024-03069-2?
• How much income is https://doi.org/10.1038/s41580-023-00690-z earning monthly?
• Find out how much https://doi.org/10.1038/s41386-024-01813-6 earns monthly
• What are the total earnings of https://doi.org/10.1186/s12864-023-09432-z?
• See how much https://doi.org/10.1186/s13048-023-01172-8 makes per month
• https://www.protocols.io/'s total income per month
• Get to know https://www.natureindex.com/'s earnings
• What's the financial gain of http://www.naturechina.com?
• Monthly income for https://www.natureasia.com/ja-jp

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref