We are analyzing https://link.springer.com/article/10.1007/s00412-009-0240-6.

Title:
Solving the Dnmt2 enigma | Chromosoma
Description:
Dnmt2 is a member of the animal DNA methyltransferase family of enzymes. While the role of other Dnmt proteins has been extensively characterized, comparably little is known about Dnmt2. This is surprising because Dnmt2 is the most widely conserved Dnmt protein, with homologues in protists, plants, fungi, and animals. In this review, we discuss the evidence supporting the seemingly contradictory roles of Dnmt2 in both DNA and RNA methylation. New studies are uncovering the enzymatic mechanisms that mediate these activities and also provide first insights into the biological functions of Dnmt2. Lastly, we also discuss observations that suggest a possible role for Dnmt2 in human health and disease, which further emphasizes the importance of defining Dnmt2-modulated cellular pathways in future studies.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Science
Social Networks

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 8,170,236 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We don't see any clear sign of profit-making.

Many websites are intended to earn money, but some serve to share ideas or build connections. Websites exist for all kinds of purposes. This might be one of them. Link.springer.com might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

article, pubmed, google, scholar, cas, dna, dnmt, methyltransferase, lyko, methylation, cytosine, nucleic, acids, res, schaefer, rna, bestor, drosophila, privacy, cookies, content, human, access, mol, biochem, analysis, information, publish, research, search, frank, protein, mammalian, methyltransferases, trna, cell, biol, yoder, cancer, genes, gene, data, log, journal, chromosoma, family, related, discover, epigenetics, chem,

Topics {✒️}

post-transcriptional nucleotide modification month download article/chapter maintenance-type dna methyltransferase displays denaturant-resistant binding replication-independent chromatin loading scaffold/matrix attachment region bisulfite sequencing methyltransferase activity article chromosoma aims full article pdf site-specific analysis nuclear matrix protein article schaefer privacy choices/manage cookies 5-cytosine dna methyltransferase dna methyltransferase homologue dna methyltransferase family related subjects dnmt2 target sites dna methylation post-mitotic neurons mammalian germ cells access dna european economic area seemingly contradictory roles cytosine methylated regions genomic imprinting disrupted maternal effect mutation epigenetic control single amino acid eukaryotic cytosine methyltransferases conditions privacy policy frank lyko dna methyltransferase rapid trna decay accepting optional cookies rna methylation article log mammalian dna press schaefer main content log usage analysis dnmt1 gene dnmt2 enigma journal finder publish article cite check access instant access fission yeast enzymes

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Solving the Dnmt2 enigma
         description:Dnmt2 is a member of the animal DNA methyltransferase family of enzymes. While the role of other Dnmt proteins has been extensively characterized, comparably little is known about Dnmt2. This is surprising because Dnmt2 is the most widely conserved Dnmt protein, with homologues in protists, plants, fungi, and animals. In this review, we discuss the evidence supporting the seemingly contradictory roles of Dnmt2 in both DNA and RNA methylation. New studies are uncovering the enzymatic mechanisms that mediate these activities and also provide first insights into the biological functions of Dnmt2. Lastly, we also discuss observations that suggest a possible role for Dnmt2 in human health and disease, which further emphasizes the importance of defining Dnmt2-modulated cellular pathways in future studies.
         datePublished:2009-09-03T00:00:00Z
         dateModified:2009-09-03T00:00:00Z
         pageStart:35
         pageEnd:40
         sameAs:https://doi.org/10.1007/s00412-009-0240-6
         keywords:
            Bisulfite Sequencing
            Methyltransferase Activity
            Dnmt2 Activity
            Dnmt2 Gene
            Dnmt2 Protein
            Cell Biology
            Developmental Biology
            Biochemistry
            general
            Human Genetics
            Animal Genetics and Genomics
            Eukaryotic Microbiology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00412-009-0240-6/MediaObjects/412_2009_240_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00412-009-0240-6/MediaObjects/412_2009_240_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00412-009-0240-6/MediaObjects/412_2009_240_Fig3_HTML.gif
         isPartOf:
            name:Chromosoma
            issn:
               1432-0886
               0009-5915
            volumeNumber:119
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Matthias Schaefer
               affiliation:
                     name:German Cancer Research Center
                     address:
                        name:Division of Epigenetics, German Cancer Research Center, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Frank Lyko
               affiliation:
                     name:German Cancer Research Center
                     address:
                        name:Division of Epigenetics, German Cancer Research Center, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Solving the Dnmt2 enigma
      description:Dnmt2 is a member of the animal DNA methyltransferase family of enzymes. While the role of other Dnmt proteins has been extensively characterized, comparably little is known about Dnmt2. This is surprising because Dnmt2 is the most widely conserved Dnmt protein, with homologues in protists, plants, fungi, and animals. In this review, we discuss the evidence supporting the seemingly contradictory roles of Dnmt2 in both DNA and RNA methylation. New studies are uncovering the enzymatic mechanisms that mediate these activities and also provide first insights into the biological functions of Dnmt2. Lastly, we also discuss observations that suggest a possible role for Dnmt2 in human health and disease, which further emphasizes the importance of defining Dnmt2-modulated cellular pathways in future studies.
      datePublished:2009-09-03T00:00:00Z
      dateModified:2009-09-03T00:00:00Z
      pageStart:35
      pageEnd:40
      sameAs:https://doi.org/10.1007/s00412-009-0240-6
      keywords:
         Bisulfite Sequencing
         Methyltransferase Activity
         Dnmt2 Activity
         Dnmt2 Gene
         Dnmt2 Protein
         Cell Biology
         Developmental Biology
         Biochemistry
         general
         Human Genetics
         Animal Genetics and Genomics
         Eukaryotic Microbiology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00412-009-0240-6/MediaObjects/412_2009_240_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00412-009-0240-6/MediaObjects/412_2009_240_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00412-009-0240-6/MediaObjects/412_2009_240_Fig3_HTML.gif
      isPartOf:
         name:Chromosoma
         issn:
            1432-0886
            0009-5915
         volumeNumber:119
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Matthias Schaefer
            affiliation:
                  name:German Cancer Research Center
                  address:
                     name:Division of Epigenetics, German Cancer Research Center, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Frank Lyko
            affiliation:
                  name:German Cancer Research Center
                  address:
                     name:Division of Epigenetics, German Cancer Research Center, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Chromosoma
      issn:
         1432-0886
         0009-5915
      volumeNumber:119
Organization:
      name:Springer-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:German Cancer Research Center
      address:
         name:Division of Epigenetics, German Cancer Research Center, Heidelberg, Germany
         type:PostalAddress
      name:German Cancer Research Center
      address:
         name:Division of Epigenetics, German Cancer Research Center, Heidelberg, Germany
         type:PostalAddress
      name:Deutsches Krebsforschungszentrum
      address:
         name:Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Matthias Schaefer
      affiliation:
            name:German Cancer Research Center
            address:
               name:Division of Epigenetics, German Cancer Research Center, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Frank Lyko
      affiliation:
            name:German Cancer Research Center
            address:
               name:Division of Epigenetics, German Cancer Research Center, Heidelberg, Germany
               type:PostalAddress
            type:Organization
            name:Deutsches Krebsforschungszentrum
            address:
               name:Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Division of Epigenetics, German Cancer Research Center, Heidelberg, Germany
      name:Division of Epigenetics, German Cancer Research Center, Heidelberg, Germany
      name:Deutsches Krebsforschungszentrum, Heidelberg, Germany
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(131)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.36s.

LINK . SPRINGER . COM {}