NATURE . COM {}

Matching Content Categories {📚}

• Education
• Science
• Animals & Wildlife

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$63,100 per month
Estimations show Nature.com's display ad online revenue falls between $42,042 and $115,616 per month.

Keywords {🔍}

article, google, scholar, cas, rna, nature, methylation, trna, dnmt, access, dna, cell, nsun, nucleic, acids, res, content, nat, methyltransferase, mol, biol, cookies, lyko, mouse, genet, research, privacy, molecular, biology, protein, schaefer, helm, modification, open, gene, epigenetics, genes, dev, stem, analysis, data, information, promotes, synthesis, cytosinec, trnas, cellular, development, motorin, cells,

Topics {✒️}

nature portfolio permissions reprints privacy policy stem cell research ovarian research nature advertising social media author information authors italy mediates myc-induced proliferation opioid-induced reward-seeking multisite-specific trna cytosine-c5 trna methylation manage preferences author correspondence trna-derived small rnas long-term opioid withdrawal springerlink instant access trna biology charges m5c methyltransferase rlmi personal data mrna-expression profiling data protection permissions gene expression cytosine-c5 methylation retina development rna cytosine methylation double mutants showed matthias schaefer trna methylation analysis codon-biased translation frank lyko dna methylation landscapes rna nucleotide methylation m5c-methyltransferase steady-state levels privacy embryonic stem cells stefanie kellner stress-induced cleavage reveals evolutionary links rna modification enzymes development competing financial interests dna methyltransferase homologue rna–methyltransferase misu rna methyltransferase misu molecular mechanisms

Questions {❓}

• Do all modifications benefit all tRNAs?
• Grand challenge commentary: RNA epigenetics?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis
         description:Although cytosine-C5 methylation is a prominent modification of tRNAs, its functional significance has been unclear. Mice that lack both the Dnmt2 and NSun2 tRNA methyltransferases showed developmental and cellular differentiation defects, and loss of Dnmt2 and NSun2 was further associated with tRNA degradation and reduced rates of protein synthesis, suggesting that this modification promotes mouse development by supporting protein synthesis. The function of cytosine-C5 methylation, a widespread modification of tRNAs, has remained obscure, particularly in mammals. We have now developed a mouse strain defective in cytosine-C5 tRNA methylation, by disrupting both the Dnmt2 and the NSun2 tRNA methyltransferases. Although the lack of either enzyme alone has no detectable effects on mouse viability, double mutants showed a synthetic lethal interaction, with an underdeveloped phenotype and impaired cellular differentiation. tRNA methylation analysis of the double-knockout mice demonstrated complementary target-site specificities for Dnmt2 and NSun2 and a complete loss of cytosine-C5 tRNA methylation. Steady-state levels of unmethylated tRNAs were substantially reduced, and loss of Dnmt2 and NSun2 was further associated with reduced rates of overall protein synthesis. These results establish a biologically important function for cytosine-C5 tRNA methylation in mammals and suggest that this modification promotes mouse development by supporting protein synthesis.
         datePublished:2012-08-12T00:00:00Z
         dateModified:2012-08-12T00:00:00Z
         pageStart:900
         pageEnd:905
         sameAs:https://doi.org/10.1038/nsmb.2357
         keywords:
            Epigenetics
            RNA modification
            tRNAs
            Life Sciences
            general
            Biochemistry
            Protein Structure
            Membrane Biology
            Biological Microscopy
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig5_HTML.jpg
         isPartOf:
            name:Nature Structural & Molecular Biology
            issn:
               1545-9985
               1545-9993
            volumeNumber:19
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Francesca Tuorto
               affiliation:
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Reinhard Liebers
               affiliation:
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Tanja Musch
               affiliation:
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Matthias Schaefer
               affiliation:
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Sarah Hofmann
               affiliation:
                     name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
                     address:
                        name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Stefanie Kellner
               affiliation:
                     name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
                     address:
                        name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Michaela Frye
               affiliation:
                     name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge
                     address:
                        name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mark Helm
               affiliation:
                     name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
                     address:
                        name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Georg Stoecklin
               affiliation:
                     name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
                     address:
                        name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Frank Lyko
               affiliation:
                     name:Deutsches Krebsforschungszentrum
                     address:
                        name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis
      description:Although cytosine-C5 methylation is a prominent modification of tRNAs, its functional significance has been unclear. Mice that lack both the Dnmt2 and NSun2 tRNA methyltransferases showed developmental and cellular differentiation defects, and loss of Dnmt2 and NSun2 was further associated with tRNA degradation and reduced rates of protein synthesis, suggesting that this modification promotes mouse development by supporting protein synthesis. The function of cytosine-C5 methylation, a widespread modification of tRNAs, has remained obscure, particularly in mammals. We have now developed a mouse strain defective in cytosine-C5 tRNA methylation, by disrupting both the Dnmt2 and the NSun2 tRNA methyltransferases. Although the lack of either enzyme alone has no detectable effects on mouse viability, double mutants showed a synthetic lethal interaction, with an underdeveloped phenotype and impaired cellular differentiation. tRNA methylation analysis of the double-knockout mice demonstrated complementary target-site specificities for Dnmt2 and NSun2 and a complete loss of cytosine-C5 tRNA methylation. Steady-state levels of unmethylated tRNAs were substantially reduced, and loss of Dnmt2 and NSun2 was further associated with reduced rates of overall protein synthesis. These results establish a biologically important function for cytosine-C5 tRNA methylation in mammals and suggest that this modification promotes mouse development by supporting protein synthesis.
      datePublished:2012-08-12T00:00:00Z
      dateModified:2012-08-12T00:00:00Z
      pageStart:900
      pageEnd:905
      sameAs:https://doi.org/10.1038/nsmb.2357
      keywords:
         Epigenetics
         RNA modification
         tRNAs
         Life Sciences
         general
         Biochemistry
         Protein Structure
         Membrane Biology
         Biological Microscopy
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_Article_BFnsmb2357_Fig5_HTML.jpg
      isPartOf:
         name:Nature Structural & Molecular Biology
         issn:
            1545-9985
            1545-9993
         volumeNumber:19
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Francesca Tuorto
            affiliation:
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Reinhard Liebers
            affiliation:
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Tanja Musch
            affiliation:
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Matthias Schaefer
            affiliation:
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Sarah Hofmann
            affiliation:
                  name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
                  address:
                     name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Stefanie Kellner
            affiliation:
                  name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
                  address:
                     name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Michaela Frye
            affiliation:
                  name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge
                  address:
                     name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mark Helm
            affiliation:
                  name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
                  address:
                     name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Georg Stoecklin
            affiliation:
                  name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
                  address:
                     name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Frank Lyko
            affiliation:
                  name:Deutsches Krebsforschungszentrum
                  address:
                     name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Structural & Molecular Biology
      issn:
         1545-9985
         1545-9993
      volumeNumber:19
Organization:
      name:Nature Publishing Group US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Deutsches Krebsforschungszentrum
      address:
         name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Deutsches Krebsforschungszentrum
      address:
         name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Deutsches Krebsforschungszentrum
      address:
         name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Deutsches Krebsforschungszentrum
      address:
         name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
      address:
         name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
      address:
         name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
         type:PostalAddress
      name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge
      address:
         name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK
         type:PostalAddress
      name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
      address:
         name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
         type:PostalAddress
      name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
      address:
         name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
      name:Deutsches Krebsforschungszentrum
      address:
         name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Francesca Tuorto
      affiliation:
            name:Deutsches Krebsforschungszentrum
            address:
               name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Reinhard Liebers
      affiliation:
            name:Deutsches Krebsforschungszentrum
            address:
               name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Tanja Musch
      affiliation:
            name:Deutsches Krebsforschungszentrum
            address:
               name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Matthias Schaefer
      affiliation:
            name:Deutsches Krebsforschungszentrum
            address:
               name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Sarah Hofmann
      affiliation:
            name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
            address:
               name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Stefanie Kellner
      affiliation:
            name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
            address:
               name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
               type:PostalAddress
            type:Organization
      name:Michaela Frye
      affiliation:
            name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge
            address:
               name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK
               type:PostalAddress
            type:Organization
      name:Mark Helm
      affiliation:
            name:Institute of Pharmacy, Johannes Gutenberg University of Mainz
            address:
               name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
               type:PostalAddress
            type:Organization
      name:Georg Stoecklin
      affiliation:
            name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum
            address:
               name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Frank Lyko
      affiliation:
            name:Deutsches Krebsforschungszentrum
            address:
               name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
      name:Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK
      name:Institute of Pharmacy, Johannes Gutenberg University of Mainz, Mainz, Germany
      name:Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, Deutsches Krebsforschungszentrum, Heidelberg, Germany
      name:Division of Epigenetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(1)

• https://twitter.com/NatureSMB

External Links {🔗}(109)

• What are the total earnings of https://link.springer.com/article/10.1038/nsmb.2357?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle?
• Get to know http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE36918's earnings
• Learn how profitable https://doi.org/10.1038%2Fnrg2341 is on a monthly basis
• How much does http://scholar.google.com/scholar_lookup?&title=DNA%20methylation%20landscapes%3A%20provocative%20insights%20from%20epigenomics&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2341&volume=9&pages=465-476&publication_year=2008&author=Suzuki%2CMM&author=Bird%2CA pull in?
• How much does https://doi.org/10.1016%2Fj.tig.2008.12.005 net monthly?
• How much profit is http://scholar.google.com/scholar_lookup?&title=Genetics%20and%20epigenetics%3A%20stability%20and%20plasticity%20during%20cellular%20differentiation&journal=Trends%20Genet.&doi=10.1016%2Fj.tig.2008.12.005&volume=25&pages=129-136&publication_year=2009&author=Mohn%2CF&author=Schubeler%2CD making per month?
• How much income does https://doi.org/10.1038%2Fnrg3230 have?
• Earnings of http://scholar.google.com/scholar_lookup?&title=Functions%20of%20DNA%20methylation%3A%20islands%2C%20start%20sites%2C%20gene%20bodies%20and%20beyond&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg3230&volume=13&pages=484-492&publication_year=2012&author=Jones%2CPA
• How much does https://doi.org/10.1101%2Fgad.1956510 rake in every month?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=tRNA%20biology%20charges%20to%20the%20front&journal=Genes%20Dev.&doi=10.1101%2Fgad.1956510&volume=24&pages=1832-1860&publication_year=2010&author=Phizicky%2CEM&author=Hopper%2CAK?
• What's the financial outcome of https://doi.org/10.1093%2Fnar%2Fgkp1117?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=5-methylcytosine%20in%20RNA%3A%20detection%2C%20enzymatic%20formation%20and%20biological%20functions&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgkp1117&volume=38&pages=1415-1430&publication_year=2010&author=Motorin%2CY&author=Lyko%2CF&author=Helm%2CM produce monthly?
• How much does https://doi.org/10.1126%2Fscience.1120976 generate monthly?
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Methylation%20of%20tRNAAsp%20by%20the%20DNA%20methyltransferase%20homolog%20Dnmt2&journal=Science&doi=10.1126%2Fscience.1120976&volume=311&pages=395-398&publication_year=2006&author=Goll%2CMG
• Discover the revenue of https://doi.org/10.1101%2Fgad.586710
• Get to know http://scholar.google.com/scholar_lookup?&title=RNA%20methylation%20by%20Dnmt2%20protects%20transfer%20RNAs%20against%20stress-induced%20cleavage&journal=Genes%20Dev.&doi=10.1101%2Fgad.586710&volume=24&pages=1590-1595&publication_year=2010&author=Schaefer%2CM's earnings
• What are the earnings of https://doi.org/10.1093%2Fnar%2F23.2.203?
• Discover the revenue of http://scholar.google.com/scholar_lookup?&title=The%20fission%20yeast%20gene%20pmt1%2B%20encodes%20a%20DNA%20methyltransferase%20homologue&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F23.2.203&volume=23&pages=203-210&publication_year=1995&author=Wilkinson%2CCR&author=Bartlett%2CR&author=Nurse%2CP&author=Bird%2CAP
• What's the monthly money flow for https://doi.org/10.1093%2Fhmg%2F7.2.279?
• What's http://scholar.google.com/scholar_lookup?&title=A%20candidate%20mammalian%20DNA%20methyltransferase%20related%20to%20pmt1p%20of%20fission%20yeast&journal=Hum.%20Mol.%20Genet.&doi=10.1093%2Fhmg%2F7.2.279&volume=7&pages=279-284&publication_year=1998&author=Yoder%2CJA&author=Bestor%2CTH's gross income?
• How much money does https://doi.org/10.1093%2Fnar%2F26.11.2536 make?
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Dnmt2%20is%20not%20required%20for%20de%20novo%20and%20maintenance%20methylation%20of%20viral%20DNA%20in%20embryonic%20stem%20cells&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2F26.11.2536&volume=26&pages=2536-2540&publication_year=1998&author=Okano%2CM&author=Xie%2CS&author=Li%2CE?
• How much money does https://doi.org/10.1261%2Frna.970408 make?
• Profit of http://scholar.google.com/scholar_lookup?&title=Human%20DNMT2%20methylates%20tRNAAsp%20molecules%20using%20a%20DNA%20methyltransferase-like%20catalytic%20mechanism&journal=RNA&doi=10.1261%2Frna.970408&volume=14&pages=1663-1670&publication_year=2008&author=Jurkowski%2CTP
• What's https://doi.org/10.1016%2Fj.jmb.2008.08.062's gross income?
• What's the revenue for http://scholar.google.com/scholar_lookup?&title=Crystal%20structure%20of%20the%20Escherichia%20coli%2023S%20rRNA%3Am5C%20methyltransferase%20RlmI%20%28YccW%29%20reveals%20evolutionary%20links%20between%20RNA%20modification%20enzymes&journal=J.%20Mol.%20Biol.&doi=10.1016%2Fj.jmb.2008.08.062&volume=383&pages=652-666&publication_year=2008&author=Sunita%2CS?
• What's the financial intake of https://doi.org/10.1016%2FB978-0-12-387685-0.00002-0?
• How much does http://scholar.google.com/scholar_lookup?&title=Natural%20history%20of%20eukaryotic%20DNA%20methylation%20systems&journal=Prog.%20Mol.%20Biol.%20Transl.%20Sci.&doi=10.1016%2FB978-0-12-387685-0.00002-0&volume=101&pages=25-104&publication_year=2011&author=Iyer%2CLM&author=Abhiman%2CS&author=Aravind%2CL make?
• Find out how much https://doi.org/10.1371%2Fjournal.pone.0028104 earns monthly
• What's the financial gain of http://scholar.google.com/scholar_lookup?&title=On%20the%20evolutionary%20origin%20of%20eukaryotic%20DNA%20methyltransferases%20and%20Dnmt2&journal=PLoS%20ONE&doi=10.1371%2Fjournal.pone.0028104&volume=6&publication_year=2011&author=Jurkowski%2CTP&author=Jeltsch%2CA?
• How much does https://link.springer.com/doi/10.1007/s00412-009-0240-6 earn?
• How much profit is http://scholar.google.com/scholar_lookup?&title=Solving%20the%20Dnmt2%20enigma&journal=Chromosoma.&doi=10.1007%2Fs00412-009-0240-6&volume=119&pages=35-40&publication_year=2010&author=Schaefer%2CM&author=Lyko%2CF making per month?
• https://doi.org/10.1093%2Fnar%2Fgkl765's financial summary
• Find out how much http://scholar.google.com/scholar_lookup?&title=Identification%20of%20human%20tRNA%3Am5C%20methyltransferase%20catalysing%20intron-dependent%20m5C%20formation%20in%20the%20first%20position%20of%20the%20anticodon%20of%20the%20pre-tRNA%20Leu%20%28CAA%29&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgkl765&volume=34&pages=6034-6043&publication_year=2006&author=Brzezicha%2CB earns monthly
• Monthly income for https://doi.org/10.1371%2Fjournal.pgen.1002403
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=The%20RNA%E2%80%93methyltransferase%20Misu%20%28NSun2%29%20poises%20epidermal%20stem%20cells%20to%20differentiate&journal=PLoS%20Genet.&doi=10.1371%2Fjournal.pgen.1002403&volume=7&publication_year=2011&author=Blanco%2CS have monthly?
• Find out how much https://doi.org/10.1017%2FS1355838299982201 earns monthly
• How much does http://scholar.google.com/scholar_lookup?&title=Multisite-specific%20tRNA%3Am5C-methyltransferase%20%28Trm4%29%20in%20yeast%20Saccharomyces%20cerevisiae%3A%20identification%20of%20the%20gene%20and%20substrate%20specificity%20of%20the%20enzyme&journal=RNA&doi=10.1017%2FS1355838299982201&volume=5&pages=1105-1118&publication_year=1999&author=Motorin%2CY&author=Grosjean%2CH rake in every month?
• How much does https://doi.org/10.1016%2Fj.cub.2006.04.027 rake in every month?
• What's http://scholar.google.com/scholar_lookup?&title=The%20RNA%20methyltransferase%20Misu%20%28NSun2%29%20mediates%20Myc-induced%20proliferation%20and%20is%20upregulated%20in%20tumors&journal=Curr.%20Biol.&doi=10.1016%2Fj.cub.2006.04.027&volume=16&pages=971-981&publication_year=2006&author=Frye%2CM&author=Watt%2CFM's gross income?
• Monthly income for https://doi.org/10.1093%2Fnar%2Fgks144
• Explore the financials of http://scholar.google.com/scholar_lookup?&title=Widespread%20occurrence%20of%205-methylcytosine%20in%20human%20coding%20and%20non-coding%20RNA&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgks144&volume=40&pages=5023-5033&publication_year=2012&author=Squires%2CJE
• Earnings of https://doi.org/10.1038%2Fncomms1692
• Income figures for http://scholar.google.com/scholar_lookup?&title=The%20tRNA%20methyltransferase%20NSun2%20stabilizes%20p16%28INK4%29%20mRNA%20by%20methylating%20the%203%E2%80%B2-untranslated%20region%20of%20p16&journal=Nat%20Commun.&doi=10.1038%2Fncomms1692&volume=3&publication_year=2012&author=Zhang%2CX
• What's the revenue for https://doi.org/10.1093%2Fnar%2Fgkn954?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=RNA%20cytosine%20methylation%20analysis%20by%20bisulfite%20sequencing&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgkn954&volume=37&publication_year=2009&author=Schaefer%2CM&author=Pollex%2CT&author=Hanna%2CK&author=Lyko%2CF
• How much does https://doi.org/10.1093%2Fnar%2Fgki012 pull in?
• What's the revenue for http://scholar.google.com/scholar_lookup?&title=Compilation%20of%20tRNA%20sequences%20and%20sequences%20of%20tRNA%20genes&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgki012&volume=33&pages=D139-D140&publication_year=2005&author=Sprinzl%2CM&author=Vassilenko%2CKS?
• Get to know https://doi.org/10.1002%2Fwrna.79's earnings
• What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=RNA%20nucleotide%20methylation&journal=Wiley%20Interdiscip.%20Rev.%20RNA&doi=10.1002%2Fwrna.79&volume=2&pages=611-631&publication_year=2011&author=Motorin%2CY&author=Helm%2CM?
• What is the monthly revenue of https://doi.org/10.1016%2Fj.febslet.2009.11.049?
• How much does http://scholar.google.com/scholar_lookup?&title=Do%20all%20modifications%20benefit%20all%20tRNAs%3F&journal=FEBS%20Lett.&doi=10.1016%2Fj.febslet.2009.11.049&volume=584&pages=265-271&publication_year=2010&author=Phizicky%2CEM&author=Alfonzo%2CJD net monthly?
• How much revenue does https://doi.org/10.1016%2Fj.molcel.2005.10.036 produce monthly?
• How much income is http://scholar.google.com/scholar_lookup?&title=Rapid%20tRNA%20decay%20can%20result%20from%20lack%20of%20nonessential%20modifications&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2005.10.036&volume=21&pages=87-96&publication_year=2006&author=Alexandrov%2CA earning monthly?
• How much profit is https://doi.org/10.1101%2Fgad.1654308 making per month?
• Find out how much http://scholar.google.com/scholar_lookup?&title=Degradation%20of%20several%20hypomodified%20mature%20tRNA%20species%20in%20Saccharomyces%20cerevisiae%20is%20mediated%20by%20Met22%20and%20the%205%E2%80%B2-3%E2%80%B2%20exonucleases%20Rat1%20and%20Xrn1&journal=Genes%20Dev.&doi=10.1101%2Fgad.1654308&volume=22&pages=1369-1380&publication_year=2008&author=Chernyakov%2CI&author=Whipple%2CJM&author=Kotelawala%2CL&author=Grayhack%2CEJ&author=Phizicky%2CEM earns monthly
• How much revenue does https://doi.org/10.1371%2Fjournal.pgen.1001247 generate?
• How profitable is http://scholar.google.com/scholar_lookup?&title=A%20quantitative%20systems%20approach%20reveals%20dynamic%20control%20of%20tRNA%20modifications%20during%20cellular%20stress&journal=PLoS%20Genet.&doi=10.1371%2Fjournal.pgen.1001247&volume=6&publication_year=2010&author=Chan%2CCT?
• How much income does https://doi.org/10.1126%2Fscience.1192430 have?
• How much does http://scholar.google.com/scholar_lookup?&title=Dom34%3AHbs1%20promotes%20subunit%20dissociation%20and%20peptidyl-tRNA%20drop-off%20to%20initiate%20no-go%20decay&journal=Science&doi=10.1126%2Fscience.1192430&volume=330&pages=369-372&publication_year=2010&author=Shoemaker%2CCJ&author=Eyler%2CDE&author=Green%2CR earn?
• What's the income of https://doi.org/10.1016%2Fj.molcel.2011.06.022?
• How much does http://scholar.google.com/scholar_lookup?&title=Angiogenin-induced%20tRNA%20fragments%20inhibit%20translation%20initiation&journal=Mol.%20Cell&doi=10.1016%2Fj.molcel.2011.06.022&volume=43&pages=613-623&publication_year=2011&author=Ivanov%2CP&author=Emara%2CMM&author=Villen%2CJ&author=Gygi%2CSP&author=Anderson%2CP pull in?
• What's https://doi.org/10.4161%2Fepi.6.1.13418's gross income?
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=The%20DNA%20methyltranferase%20Dnmt2%20participates%20in%20RNA%20processing%20during%20cellular%20stress&journal=Epigenetics&doi=10.4161%2Fepi.6.1.13418&volume=6&pages=103-113&publication_year=2011&author=Thiagarajan%2CD&author=Dev%2CRR&author=Khosla%2CS?
• What is the earnings of https://doi.org/10.1038%2Fncomms1938?
• How much does http://scholar.google.com/scholar_lookup?&title=Reprogramming%20of%20tRNA%20modifications%20controls%20the%20oxidative%20stress%20response%20by%20codon-biased%20translation%20of%20proteins&journal=Nat.%20Commun.&doi=10.1038%2Fncomms1938&volume=3&publication_year=2012&author=Chan%2CCT pull in?
• What's the financial gain of https://doi.org/10.1016%2Fj.stem.2008.03.013?
• What's the income of http://scholar.google.com/scholar_lookup?&title=A%20hierarchical%20network%20controls%20protein%20translation%20during%20murine%20embryonic%20stem%20cell%20self-renewal%20and%20differentiation&journal=Cell%20Stem%20Cell&doi=10.1016%2Fj.stem.2008.03.013&volume=2&pages=448-460&publication_year=2008&author=Sampath%2CP?
• What are the earnings of https://doi.org/10.1101%2Fgad.1472907?
• Get to know http://scholar.google.com/scholar_lookup?&title=Dnmt2%20functions%20in%20the%20cytoplasm%20to%20promote%20liver%2C%20brain%2C%20and%20retina%20development%20in%20zebrafish&journal=Genes%20Dev.&doi=10.1101%2Fgad.1472907&volume=21&pages=261-266&publication_year=2007&author=Rai%2CK's earnings
• What's the monthly money flow for https://doi.org/10.1038%2Fnchembio.482?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Grand%20challenge%20commentary%3A%20RNA%20epigenetics%3F&journal=Nat.%20Chem.%20Biol.&doi=10.1038%2Fnchembio.482&volume=6&pages=863-865&publication_year=2010&author=He%2CC make?
• Earnings of https://doi.org/10.1083%2Fjcb.17.2.299
• http://scholar.google.com/scholar_lookup?&title=Quantitative%20studies%20of%20the%20growth%20of%20mouse%20embryo%20cells%20in%20culture%20and%20their%20development%20into%20established%20lines&journal=J.%20Cell%20Biol.&doi=10.1083%2Fjcb.17.2.299&volume=17&pages=299-313&publication_year=1963&author=Todaro%2CGJ&author=Green%2CH income
• How much does https://doi.org/10.1093%2Fnar%2Fgkr449 rake in every month?
• How much does http://scholar.google.com/scholar_lookup?&title=A%20multifunctional%20bioconjugate%20module%20for%20versatile%20photoaffinity%20labeling%20and%20click%20chemistry%20of%20RNA&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgkr449&volume=39&pages=7348-7360&publication_year=2011&author=Kellner%2CS&author=Seidu-Larry%2CS&author=Burhenne%2CJ&author=Motorin%2CY&author=Helm%2CM bring in each month?
• Revenue of https://citation-needed.springer.com/v2/references/10.1038/nsmb.2357?format=refman&flavour=references
• How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Francesca%20Tuorto generate?
• Check the income stats for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Francesca%20Tuorto%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much cash flow does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Reinhard%20Liebers have monthly?
• What's the profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Reinhard%20Liebers%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Tanja%20Musch bring in?
• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Tanja%20Musch%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Matthias%20Schaefer make?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Matthias%20Schaefer%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Sarah%20Hofmann generate?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Sarah%20Hofmann%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
• How much income does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Stefanie%20Kellner have?
• What's the financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Stefanie%20Kellner%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Michaela%20Frye gross monthly?
• What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Michaela%20Frye%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mark%20Helm generate?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mark%20Helm%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
• What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Georg%20Stoecklin?
• What's the revenue for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Georg%20Stoecklin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What are the total earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Frank%20Lyko?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Frank%20Lyko%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
• What are the total earnings of https://static-content.springer.com/esm/art%3A10.1038%2Fnsmb.2357/MediaObjects/41594_2012_BFnsmb2357_MOESM11_ESM.pdf?
• What's the monthly income of https://s100.copyright.com/AppDispatchServlet?title=RNA%20cytosine%20methylation%20by%20Dnmt2%20and%20NSun2%20promotes%20tRNA%20stability%20and%20protein%20synthesis&author=Francesca%20Tuorto%20et%20al&contentID=10.1038%2Fnsmb.2357©right=Springer%20Nature%20America%2C%20Inc.&publication=1545-9993&publicationDate=2012-08-12&publisherName=SpringerNature&orderBeanReset=true?
• What's the monthly money flow for https://citation-needed.springer.com/v2/references/10.1038/nsmb.2357?format=refman&flavour=citation?
• Profit of https://doi.org/10.1038/s41388-024-03069-2
• What are the earnings of https://doi.org/10.1038/s41580-023-00690-z?
• How much revenue does https://doi.org/10.1038/s41386-024-01813-6 produce monthly?
• How much profit does https://doi.org/10.1186/s12864-023-09432-z make?
• What's https://doi.org/10.1186/s13048-023-01172-8's gross income?
• How much profit is https://www.protocols.io/ making per month?
• How profitable is https://www.natureindex.com/?
• How profitable is http://www.naturechina.com?
• https://www.natureasia.com/ja-jp's financial summary

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref