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Title:
Prenatal exposure to drugs: effects on brain development and implications for policy and education | Nature Reviews Neuroscience
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Exposurein uteroto drugs that modulate neurotransmitter systems present during early development can affect brain architecture and function. Levitt and colleagues consider what science has discovered about the effects of prenatal drug exposure and how this knowledge might influence public policy. The effects of prenatal exposure to drugs on brain development are complex and are modulated by the timing, dose and route of drug exposure. It is difficult to assess these effects in clinical cohorts as these are beset with problems such as multiple exposures and difficulties in documenting use patterns. This can lead to misinterpretation of research findings by the general public, the media and policy makers, who may mistakenly assume that the legal status of a drug correlates with its biological impact on fetal brain development and long-term clinical outcomes. It is important to close the gap between what science tells us about the impact of prenatal drug exposure on the fetus and the mother and what we do programmatically with regard to at-risk populations.
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pubmed, google, scholar, cas, exposure, prenatal, brain, development, cocaine, res, effects, pregnancy, neurosci, central, cortex, nature, levitt, fetal, methamphetamine, drug, nicotine, rat, psychiatry, dopamine, behavioral, receptor, serotonin, ethanol, neuroscience, stanwood, health, access, neonatal, alcohol, developmental, neurotoxicol, teratol, children, cerebral, maternal, cell, child, drugs, pharmacol, dev, outcomes, rats, sci, exposed, exp,
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Questions {β}
- Does the use of nicotine replacement therapy during pregnancy affect pregnancy outcomes?
- Fetal nicotine or cocaine exposure: which one is worse?
- From oocyte to neuron: do neurotransmitters function in the same way throughout development?
- If nicotine is a developmental neurotoxicant in animal studies, dare we recommend nicotine replacement therapy in pregnant women and adolescents?
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description:Exposurein uteroto drugs that modulate neurotransmitter systems present during early development can affect brain architecture and function. Levitt and colleagues consider what science has discovered about the effects of prenatal drug exposure and how this knowledge might influence public policy. The effects of prenatal exposure to drugs on brain development are complex and are modulated by the timing, dose and route of drug exposure. It is difficult to assess these effects in clinical cohorts as these are beset with problems such as multiple exposures and difficulties in documenting use patterns. This can lead to misinterpretation of research findings by the general public, the media and policy makers, who may mistakenly assume that the legal status of a drug correlates with its biological impact on fetal brain development and long-term clinical outcomes. It is important to close the gap between what science tells us about the impact of prenatal drug exposure on the fetus and the mother and what we do programmatically with regard to at-risk populations.
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