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Title:
The gut microbiota in IBD | Nature Reviews Gastroenterology & Hepatology
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IBD is emerging as a worldwide epidemic. Patients with IBD often have an abnormal gut microbiota; however, it is unknown whether this feature is a cause or a consequence of disease. In this article, Francisco Guarner and colleagues review our current knowledge of the human gut microbiota, describe changes observed in patients with IBD and discuss whether such changes might explain the pathophysiological characteristics of IBD. IBD—ulcerative colitis and Crohn
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- Do metalloproteinases contribute to tissue destruction or remodeling in the inflamed gut?
- TH17 cells in autoimmunity and immunodeficiency: protective or pathogenic?
- What is the role of the enteric commensal flora in IBD?
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