
NATURE . COM {
}
Title:
Genome-wide copy number analysis of single cells | Nature Protocols
Description:
Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells in which information regarding genetic heterogeneity is lost. Here we present a protocol that allows for the genome-wide copy number analysis of single nuclei isolated from mixed populations of cells. Single-nucleus sequencing (SNS), combines flow sorting of single nuclei on the basis of DNA content and whole-genome amplification (WGA); this is followed by next-generation sequencing to quantize genomic intervals in a genome-wide manner. Multiplexing of single cells is discussed. In addition, we outline informatic approaches that correct for biases inherent in the WGA procedure and allow for accurate determination of copy number profiles. All together, the protocol takes โผ3 d from flow cytometry to sequence-ready DNA libraries.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {๐}
- Education
- Science
- Technology & Computing
Content Management System {๐}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {๐}
What is the average monthly size of nature.com audience?
๐ Monumental Traffic: 20M - 50M visitors per month
Based on our best estimate, this website will receive around 42,194,993 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {๐ธ}
Display Ads {๐ฏ}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {๐ฐ}
Display Ads {๐ฏ}
$531,700 per month
Our calculations suggest that Nature.com earns between $354,480 and $974,820 monthly online from display advertisements.
Keywords {๐}
article, google, scholar, nature, cas, cancer, data, copy, number, sequencing, nat, single, access, content, genet, supplementary, analysis, human, genome, research, cookies, cells, methods, dna, evolution, privacy, information, genomewide, variation, genomic, breast, cell, texas, protocols, protocol, published, baslan, wigler, nicholas, navin, hicks, genetic, open, rev, singlecell, bioinformatics, development, usa, advertising, subscribe,
Topics {โ๏ธ}
sequence-ready dna libraries nature portfolio permissions reprints privacy policy body mass index sequence alignment/map format advertising cancer research somatic copy-number alteration social media single-cell genome sequencing institutional subscriptions read author information authors hbv-driven hepatocellular carcinoma childhood myelodysplastic syndromesโchallenge input-program-output labels dna cell-cycle analysis copy number variants nature 463 nature 461 nature 464 nature 467 nature 469 nature 472 nature author correspondence single-cell sequencing genome-wide association testing springerlink instant access copy number profiles high-resolution mapping copy-number alterations personalized copy number copy number estimation joint copy number copy number determination cancer development permissions breast cancer patients single-nucleus sequencing article initially published single nucleotide resolution technology development cold spring harbor change 25 february 2016 human genome genome-wide manner massively parallel sequencing single catastrophic event
Schema {๐บ๏ธ}
WebPage:
mainEntity:
headline:Genome-wide copy number analysis of single cells
description:Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells in which information regarding genetic heterogeneity is lost. Here we present a protocol that allows for the genome-wide copy number analysis of single nuclei isolated from mixed populations of cells. Single-nucleus sequencing (SNS), combines flow sorting of single nuclei on the basis of DNA content and whole-genome amplification (WGA); this is followed by next-generation sequencing to quantize genomic intervals in a genome-wide manner. Multiplexing of single cells is discussed. In addition, we outline informatic approaches that correct for biases inherent in the WGA procedure and allow for accurate determination of copy number profiles. All together, the protocol takes รขยยผ3 d from flow cytometry to sequence-ready DNA libraries.
datePublished:2012-05-03T00:00:00Z
dateModified:2016-02-24T00:00:00Z
pageStart:1024
pageEnd:1041
sameAs:https://doi.org/10.1038/nprot.2012.039
keywords:
Bioinformatics
Library construction
Structural variation
Whole genome amplification
Life Sciences
general
Biological Techniques
Analytical Chemistry
Microarrays
Computational Biology/Bioinformatics
Organic Chemistry
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figa_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figb_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figc_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figd_HTML.gif
isPartOf:
name:Nature Protocols
issn:
1750-2799
1754-2189
volumeNumber:7
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Timour Baslan
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
type:Organization
type:Person
name:Jude Kendall
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Linda Rodgers
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Hilary Cox
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Mike Riggs
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Asya Stepansky
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Jennifer Troge
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Kandasamy Ravi
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Diane Esposito
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:B Lakshmi
affiliation:
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
type:Organization
type:Person
name:Michael Wigler
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Nicholas Navin
affiliation:
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:James Hicks
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Genome-wide copy number analysis of single cells
description:Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells in which information regarding genetic heterogeneity is lost. Here we present a protocol that allows for the genome-wide copy number analysis of single nuclei isolated from mixed populations of cells. Single-nucleus sequencing (SNS), combines flow sorting of single nuclei on the basis of DNA content and whole-genome amplification (WGA); this is followed by next-generation sequencing to quantize genomic intervals in a genome-wide manner. Multiplexing of single cells is discussed. In addition, we outline informatic approaches that correct for biases inherent in the WGA procedure and allow for accurate determination of copy number profiles. All together, the protocol takes รขยยผ3 d from flow cytometry to sequence-ready DNA libraries.
datePublished:2012-05-03T00:00:00Z
dateModified:2016-02-24T00:00:00Z
pageStart:1024
pageEnd:1041
sameAs:https://doi.org/10.1038/nprot.2012.039
keywords:
Bioinformatics
Library construction
Structural variation
Whole genome amplification
Life Sciences
general
Biological Techniques
Analytical Chemistry
Microarrays
Computational Biology/Bioinformatics
Organic Chemistry
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figa_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figb_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figc_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figd_HTML.gif
isPartOf:
name:Nature Protocols
issn:
1750-2799
1754-2189
volumeNumber:7
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Timour Baslan
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
type:Organization
type:Person
name:Jude Kendall
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Linda Rodgers
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Hilary Cox
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Mike Riggs
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Asya Stepansky
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Jennifer Troge
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Kandasamy Ravi
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Diane Esposito
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:B Lakshmi
affiliation:
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
type:Organization
type:Person
name:Michael Wigler
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Nicholas Navin
affiliation:
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:James Hicks
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature Protocols
issn:
1750-2799
1754-2189
volumeNumber:7
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Timour Baslan
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
type:Organization
name:Jude Kendall
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Linda Rodgers
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Hilary Cox
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Mike Riggs
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Asya Stepansky
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Jennifer Troge
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Kandasamy Ravi
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Diane Esposito
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:B Lakshmi
affiliation:
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
type:Organization
name:Michael Wigler
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Nicholas Navin
affiliation:
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:James Hicks
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {๐}(105)
- What's the monthly money flow for https://doi.org/10.1038/nprot0316.616b?
- Explore the financials of https://link.springer.com/article/10.1038/nprot.2012.039?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle
- Find out how much http://www.ncbi.nlm.nih.gov/sra?term=SRR054616 earns monthly
- How much profit does https://doi.org/10.1038%2Fnrg2149 generate?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Copy%20number%20variants%20and%20genetic%20traits%3A%20closer%20to%20the%20resolution%20of%20phenotypic%20to%20genotypic%20variability&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2149&volume=8&pages=639-646&publication_year=2007&author=Beckmann%2CJS&author=Estivill%2CX&author=Antonarakis%2CSE generate?
- Learn how profitable https://doi.org/10.1371%2Fjournal.pgen.1000249 is on a monthly basis
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=High-resolution%20copy-number%20variation%20map%20reflects%20human%20olfactory%20receptor%20diversity%20and%20evolution&journal=PLoS%20Genet.&doi=10.1371%2Fjournal.pgen.1000249&volume=4&publication_year=2008&author=Hasin%2CY?
- What's the financial gain of https://doi.org/10.1038%2Fng2123?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Diet%20and%20the%20evolution%20of%20human%20amylase%20gene%20copy%20number%20variation&journal=Nat.%20Genet.&doi=10.1038%2Fng2123&volume=39&pages=1256-1260&publication_year=2007&author=Perry%2CGH?
- What are the earnings of https://doi.org/10.1038%2Fng.686?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Association%20analyses%20of%20249%2C796%20individuals%20reveal%2018%20new%20loci%20associated%20with%20body%20mass%20index&journal=Nat.%20Genet.&doi=10.1038%2Fng.686&volume=42&pages=937-948&publication_year=2010&author=Speliotes%2CEK?
- How much money does https://doi.org/10.1126%2Fscience.1138659 generate?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Strong%20association%20of%20de%20novo%20copy%20number%20mutations%20with%20autism&journal=Science&doi=10.1126%2Fscience.1138659&volume=316&pages=445-449&publication_year=2007&author=Sebat%2CJ?
- How much does https://doi.org/10.1038%2Fnature08822 make?
- How much does http://scholar.google.com/scholar_lookup?&title=The%20landscape%20of%20somatic%20copy-number%20alteration%20across%20human%20cancers&journal=Nature&doi=10.1038%2Fnature08822&volume=463&pages=899-905&publication_year=2010&author=Beroukhim%2CR earn?
- What's the revenue for https://doi.org/10.1038%2Fnature08768?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Signatures%20of%20mutation%20and%20selection%20in%20the%20cancer%20genome&journal=Nature&doi=10.1038%2Fnature08768&volume=463&pages=893-898&publication_year=2010&author=Bignell%2CGR?
- Earnings of https://doi.org/10.1126%2Fscitranslmed.3000611
- How much profit does http://scholar.google.com/scholar_lookup?&title=Genomic%20architecture%20characterizes%20tumor%20progression%20paths%20and%20fate%20in%20breast%20cancer%20patients&journal=Sci.%20Transl.%20Med.&doi=10.1126%2Fscitranslmed.3000611&volume=2&publication_year=2010&author=Russnes%2CHG generate?
- What's the revenue for https://doi.org/10.2217%2Ffon.10.56?
- How profitable is http://scholar.google.com/scholar_lookup?&title=DNA%20amplifications%20in%20breast%20cancer%3A%20genotypic-phenotypic%20correlations&journal=Future%20Oncol.&doi=10.2217%2Ffon.10.56&volume=6&pages=967-984&publication_year=2010&author=Shiu%2CKK&author=Natrajan%2CR&author=Geyer%2CFC&author=Ashworth%2CA&author=Reis-Filho%2CJS?
- How much does https://doi.org/10.1016%2Fj.drudis.2008.06.007 pull in monthly?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20array%20CGH%20and%20its%20clinical%20applications&journal=Drug%20Discov.%20Today&doi=10.1016%2Fj.drudis.2008.06.007&volume=13&pages=760-770&publication_year=2008&author=Shinawi%2CM&author=Cheung%2CSW produce monthly?
- Revenue of https://doi.org/10.1038%2Fnrc2771
- Monthly income for http://scholar.google.com/scholar_lookup?&title=A%20census%20of%20amplified%20and%20overexpressed%20human%20cancer%20genes&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc2771&volume=10&pages=59-64&publication_year=2010&author=Santarius%2CT&author=Shipley%2CJ&author=Brewer%2CD&author=Stratton%2CMR&author=Cooper%2CCS
- See how much https://doi.org/10.1038%2Fng1569 makes per month
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Array%20comparative%20genomic%20hybridization%20and%20its%20applications%20in%20cancer&journal=Nat.%20Genet.&doi=10.1038%2Fng1569&volume=37&issue=suppl.&pages=S11-17&publication_year=2005&author=Pinkel%2CD&author=Albertson%2CDG each month?
- How much money does https://doi.org/10.1002%2Fgcc.20797 generate?
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Clonal%20heterogeneity%20in%20childhood%20myelodysplastic%20syndromes%E2%80%94challenge%20for%20the%20detection%20of%20chromosomal%20imbalances%20by%20array-CGH&journal=Genes%20Chromosomes%20Cancer&doi=10.1002%2Fgcc.20797&volume=49&pages=885-900&publication_year=2010&author=Praulich%2CI?
- How much revenue does https://doi.org/10.1038%2Fnrg2626 produce monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Sequencing%20technologies%E2%80%94the%20next%20generation&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2626&volume=11&pages=31-46&publication_year=2010&author=Metzker%2CML pull in?
- How much money does https://doi.org/10.1016%2Fj.tig.2007.12.007 make?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=The%20impact%20of%20next-generation%20sequencing%20technology%20on%20genetics&journal=Trends%20Genet.&doi=10.1016%2Fj.tig.2007.12.007&volume=24&pages=133-141&publication_year=2008&author=Mardis%2CER
- How much does https://doi.org/10.1038%2Fnrg2841 pull in?
- How much money does http://scholar.google.com/scholar_lookup?&title=Advances%20in%20understanding%20cancer%20genomes%20through%20second-generation%20sequencing&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2841&volume=11&pages=685-696&publication_year=2010&author=Meyerson%2CM&author=Gabriel%2CS&author=Getz%2CG generate?
- Discover the revenue of https://doi.org/10.1038%2Fnmeth.1276
- How much revenue does http://scholar.google.com/scholar_lookup?&title=High-resolution%20mapping%20of%20copy-number%20alterations%20with%20massively%20parallel%20sequencing&journal=Nat.%20Methods&doi=10.1038%2Fnmeth.1276&volume=6&pages=99-103&publication_year=2009&author=Chiang%2CDY generate?
- What's the monthly money flow for https://doi.org/10.1038%2Fng.437?
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Personalized%20copy%20number%20and%20segmental%20duplication%20maps%20using%20next-generation%20sequencing&journal=Nat.%20Genet.&doi=10.1038%2Fng.437&volume=41&pages=1061-1067&publication_year=2009&author=Alkan%2CC?
- How much does https://doi.org/10.1038%2Fnature08489 make?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Mutational%20evolution%20in%20a%20lobular%20breast%20tumour%20profiled%20at%20single%20nucleotide%20resolution&journal=Nature&doi=10.1038%2Fnature08489&volume=461&pages=809-813&publication_year=2009&author=Shah%2CSP
- What's https://doi.org/10.1038%2Fnature08989's gross income?
- See how much http://scholar.google.com/scholar_lookup?&title=Genome%20remodelling%20in%20a%20basal-like%20breast%20cancer%20metastasis%20and%20xenograft&journal=Nature&doi=10.1038%2Fnature08989&volume=464&pages=999-1005&publication_year=2010&author=Ding%2CL makes per month
- How much does https://doi.org/10.1038%2Fnature09460 pull in monthly?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=The%20patterns%20and%20dynamics%20of%20genomic%20instability%20in%20metastatic%20pancreatic%20cancer&journal=Nature&doi=10.1038%2Fnature09460&volume=467&pages=1109-1113&publication_year=2010&author=Campbell%2CPJ
- How much profit does https://doi.org/10.1038%2Fnature09515 generate?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Distant%20metastasis%20occurs%20late%20during%20the%20genetic%20evolution%20of%20pancreatic%20cancer&journal=Nature&doi=10.1038%2Fnature09515&volume=467&pages=1114-1117&publication_year=2010&author=Yachida%2CS
- How much does https://doi.org/10.1038%2Fnature09650 bring in each month?
- Earnings of http://scholar.google.com/scholar_lookup?&title=Genetic%20variegation%20of%20clonal%20architecture%20and%20propagating%20cells%20in%20leukaemia&journal=Nature&doi=10.1038%2Fnature09650&volume=469&pages=356-361&publication_year=2011&author=Anderson%2CK
- Discover the revenue of https://doi.org/10.1038%2Fnature09807
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Tumour%20evolution%20inferred%20by%20single-cell%20sequencing&journal=Nature&doi=10.1038%2Fnature09807&volume=472&pages=90-94&publication_year=2011&author=Navin%2CN?
- How much does https://link.springer.com/doi/10.1186/gb-2009-10-3-r25 rake in every month?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Ultrafast%20and%20memory-efficient%20alignment%20of%20short%20DNA%20sequences%20to%20the%20human%20genome&journal=Genome%20Biol.&doi=10.1186%2Fgb-2009-10-3-r25&volume=10&publication_year=2009&author=Langmead%2CB&author=Trapnell%2CC&author=Pop%2CM&author=Salzberg%2CSL
- https://doi.org/10.1093%2Fbioinformatics%2Fbtp352's revenue stream
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=The%20Sequence%20Alignment%2FMap%20format%20and%20SAMtools&journal=Bioinformatics&doi=10.1093%2Fbioinformatics%2Fbtp352&volume=15&pages=2078-2079&publication_year=2009&author=Li%2CH each month?
- Monthly income for https://doi.org/10.1093%2Fbioinformatics%2Fbtl646
- Get to know http://scholar.google.com/scholar_lookup?&title=A%20faster%20cicular%20binary%20segmentation%20algorithm%20for%20the%20analysis%20of%20array%20CGH%20data&journal=Bioinformatics&doi=10.1093%2Fbioinformatics%2Fbtl646&volume=23&pages=657-63&publication_year=2007&author=Venkatraman%2CES&author=Olshen%2CAB's earnings
- https://doi.org/10.1002%2Fcyto.1171 income
- How much income is http://scholar.google.com/scholar_lookup?&title=Doublet%20discrimination%20in%20DNA%20cell-cycle%20analysis&journal=Cytometry&doi=10.1002%2Fcyto.1171&volume=46&pages=296-306&publication_year=2001&author=Wersto%2CRP earning monthly?
- What's https://doi.org/10.1038%2Fsj.cdd.4401161's gross income?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Degradation%20of%20chromosomal%20DNA%20during%20apoptosis&journal=Cell%20Death%20Differ&doi=10.1038%2Fsj.cdd.4401161&volume=10&pages=108-116&publication_year=2003&author=Nagata%2CS&author=Nagase%2CH&author=Kawane%2CK&author=Mukae%2CN&author=Fukuyama%2CH?
- How much does https://doi.org/10.1016%2Fj.cell.2010.11.055 earn?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Massive%20genomic%20rearragement%20acquired%20in%20a%20single%20catastrophic%20event%20during%20cancer%20development&journal=Cell&doi=10.1016%2Fj.cell.2010.11.055&volume=144&pages=27-40&publication_year=2011&author=Stephans%2CPJ generate?
- How much does https://citation-needed.springer.com/v2/references/10.1038/nprot.2012.039?format=refman&flavour=references gross monthly?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Timour%20Baslan pull in monthly?
- Check the income stats for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Timour%20Baslan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jude%20Kendall generate?
- Find out how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jude%20Kendall%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earns monthly
- What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Linda%20Rodgers?
- What's the revenue for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Linda%20Rodgers%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Hilary%20Cox
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Hilary%20Cox%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
- How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mike%20Riggs generate?
- What's the financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mike%20Riggs%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Learn how profitable https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Asya%20Stepansky is on a monthly basis
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Asya%20Stepansky%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
- What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jennifer%20Troge's gross income?
- Get to know https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jennifer%20Troge%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's earnings
- How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kandasamy%20Ravi earning monthly?
- How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kandasamy%20Ravi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Diane%20Esposito gross monthly?
- What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Diane%20Esposito%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Check the income stats for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=B%20Lakshmi
- What are the total earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22B%20Lakshmi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Michael%20Wigler make?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Michael%20Wigler%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en net monthly?
- Discover the revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Nicholas%20Navin
- What's the revenue for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Nicholas%20Navin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Income figures for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=James%20Hicks
- How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22James%20Hicks%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
- How much revenue does https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM448_ESM.eps generate?
- How much does https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM449_ESM.zip rake in every month?
- Explore the financials of https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM450_ESM.zip
- How much revenue does https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM451_ESM.txt generate?
- https://s100.copyright.com/AppDispatchServlet?title=Genome-wide%20copy%20number%20analysis%20of%20single%20cells&author=Timour%20Baslan%20et%20al&contentID=10.1038%2Fnprot.2012.039©right=Springer%20Nature%20Limited&publication=1754-2189&publicationDate=2012-05-03&publisherName=SpringerNature&orderBeanReset=true's revenue stream
- Monthly income for https://citation-needed.springer.com/v2/references/10.1038/nprot.2012.039?format=refman&flavour=citation
- How much does https://doi.org/10.1038/s41467-023-40378-8 make?
- How much income is https://doi.org/10.1007/s10577-023-09740-w earning monthly?
- What are the total earnings of https://doi.org/10.1186/s12920-022-01264-2?
- What's the monthly money flow for https://doi.org/10.1186/s40478-022-01452-2?
- What's the profit of https://doi.org/10.1038/s41588-022-01180-2?
- What's the income generated by https://www.protocols.io/ each month?
- Find out how much https://www.natureindex.com/ earns monthly
- Explore the financials of http://www.naturechina.com
- Earnings of https://www.natureasia.com/ja-jp
Analytics and Tracking {๐}
- Google Tag Manager
Libraries {๐}
- Foundation
- Prism.js
- Zoom.js
Emails and Hosting {โ๏ธ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {๐ฆ}
- Crossref