
NATURE . COM {
}
Title:
Genome-wide copy number analysis of single cells | Nature Protocols
Description:
Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells in which information regarding genetic heterogeneity is lost. Here we present a protocol that allows for the genome-wide copy number analysis of single nuclei isolated from mixed populations of cells. Single-nucleus sequencing (SNS), combines flow sorting of single nuclei on the basis of DNA content and whole-genome amplification (WGA); this is followed by next-generation sequencing to quantize genomic intervals in a genome-wide manner. Multiplexing of single cells is discussed. In addition, we outline informatic approaches that correct for biases inherent in the WGA procedure and allow for accurate determination of copy number profiles. All together, the protocol takes โผ3 d from flow cytometry to sequence-ready DNA libraries.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {๐}
- Education
- Science
- Technology & Computing
Content Management System {๐}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {๐}
What is the average monthly size of nature.com audience?
๐๐ Tremendous Traffic: 10M - 20M visitors per month
Based on our best estimate, this website will receive around 17,216,220 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {๐ธ}
Display Ads {๐ฏ}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {๐ฐ}
Display Ads {๐ฏ}
$217,000 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $144,658 to $397,810.
Keywords {๐}
article, google, scholar, nature, cas, cancer, data, copy, number, sequencing, nat, single, access, content, genet, supplementary, analysis, human, genome, research, cookies, cells, methods, dna, evolution, privacy, information, genomewide, variation, genomic, breast, cell, texas, protocols, protocol, published, baslan, wigler, nicholas, navin, hicks, genetic, open, rev, singlecell, bioinformatics, development, usa, advertising, subscribe,
Topics {โ๏ธ}
sequence-ready dna libraries nature portfolio permissions reprints privacy policy body mass index sequence alignment/map format advertising cancer research somatic copy-number alteration social media single-cell genome sequencing institutional subscriptions read author information authors hbv-driven hepatocellular carcinoma childhood myelodysplastic syndromesโchallenge input-program-output labels dna cell-cycle analysis copy number variants nature 463 nature 461 nature 464 nature 467 nature 469 nature 472 nature author correspondence single-cell sequencing genome-wide association testing springerlink instant access copy number profiles high-resolution mapping copy-number alterations personalized copy number copy number estimation joint copy number copy number determination cancer development permissions breast cancer patients single-nucleus sequencing article initially published single nucleotide resolution technology development cold spring harbor change 25 february 2016 human genome genome-wide manner massively parallel sequencing single catastrophic event
Schema {๐บ๏ธ}
WebPage:
mainEntity:
headline:Genome-wide copy number analysis of single cells
description:Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells in which information regarding genetic heterogeneity is lost. Here we present a protocol that allows for the genome-wide copy number analysis of single nuclei isolated from mixed populations of cells. Single-nucleus sequencing (SNS), combines flow sorting of single nuclei on the basis of DNA content and whole-genome amplification (WGA); this is followed by next-generation sequencing to quantize genomic intervals in a genome-wide manner. Multiplexing of single cells is discussed. In addition, we outline informatic approaches that correct for biases inherent in the WGA procedure and allow for accurate determination of copy number profiles. All together, the protocol takes รขยยผ3 d from flow cytometry to sequence-ready DNA libraries.
datePublished:2012-05-03T00:00:00Z
dateModified:2016-02-24T00:00:00Z
pageStart:1024
pageEnd:1041
sameAs:https://doi.org/10.1038/nprot.2012.039
keywords:
Bioinformatics
Library construction
Structural variation
Whole genome amplification
Life Sciences
general
Biological Techniques
Analytical Chemistry
Microarrays
Computational Biology/Bioinformatics
Organic Chemistry
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figa_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figb_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figc_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figd_HTML.gif
isPartOf:
name:Nature Protocols
issn:
1750-2799
1754-2189
volumeNumber:7
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Timour Baslan
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
type:Organization
type:Person
name:Jude Kendall
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Linda Rodgers
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Hilary Cox
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Mike Riggs
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Asya Stepansky
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Jennifer Troge
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Kandasamy Ravi
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Diane Esposito
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:B Lakshmi
affiliation:
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
type:Organization
type:Person
name:Michael Wigler
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Nicholas Navin
affiliation:
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:James Hicks
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Genome-wide copy number analysis of single cells
description:Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells in which information regarding genetic heterogeneity is lost. Here we present a protocol that allows for the genome-wide copy number analysis of single nuclei isolated from mixed populations of cells. Single-nucleus sequencing (SNS), combines flow sorting of single nuclei on the basis of DNA content and whole-genome amplification (WGA); this is followed by next-generation sequencing to quantize genomic intervals in a genome-wide manner. Multiplexing of single cells is discussed. In addition, we outline informatic approaches that correct for biases inherent in the WGA procedure and allow for accurate determination of copy number profiles. All together, the protocol takes รขยยผ3 d from flow cytometry to sequence-ready DNA libraries.
datePublished:2012-05-03T00:00:00Z
dateModified:2016-02-24T00:00:00Z
pageStart:1024
pageEnd:1041
sameAs:https://doi.org/10.1038/nprot.2012.039
keywords:
Bioinformatics
Library construction
Structural variation
Whole genome amplification
Life Sciences
general
Biological Techniques
Analytical Chemistry
Microarrays
Computational Biology/Bioinformatics
Organic Chemistry
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figa_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figb_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figc_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figd_HTML.gif
isPartOf:
name:Nature Protocols
issn:
1750-2799
1754-2189
volumeNumber:7
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Timour Baslan
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
type:Organization
type:Person
name:Jude Kendall
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Linda Rodgers
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Hilary Cox
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Mike Riggs
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Asya Stepansky
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Jennifer Troge
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Kandasamy Ravi
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Diane Esposito
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:B Lakshmi
affiliation:
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
type:Organization
type:Person
name:Michael Wigler
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Nicholas Navin
affiliation:
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:James Hicks
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature Protocols
issn:
1750-2799
1754-2189
volumeNumber:7
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Timour Baslan
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
type:Organization
name:Jude Kendall
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Linda Rodgers
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Hilary Cox
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Mike Riggs
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Asya Stepansky
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Jennifer Troge
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Kandasamy Ravi
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Diane Esposito
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:B Lakshmi
affiliation:
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
type:Organization
name:Michael Wigler
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Nicholas Navin
affiliation:
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:James Hicks
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {๐}(105)
- How much does https://doi.org/10.1038/nprot0316.616b earn?
- What's the revenue for https://link.springer.com/article/10.1038/nprot.2012.039?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle?
- Monthly income for http://www.ncbi.nlm.nih.gov/sra?term=SRR054616
- What's the total monthly financial gain of https://doi.org/10.1038%2Fnrg2149?
- How much does http://scholar.google.com/scholar_lookup?&title=Copy%20number%20variants%20and%20genetic%20traits%3A%20closer%20to%20the%20resolution%20of%20phenotypic%20to%20genotypic%20variability&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2149&volume=8&pages=639-646&publication_year=2007&author=Beckmann%2CJS&author=Estivill%2CX&author=Antonarakis%2CSE generate monthly?
- Revenue of https://doi.org/10.1371%2Fjournal.pgen.1000249
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=High-resolution%20copy-number%20variation%20map%20reflects%20human%20olfactory%20receptor%20diversity%20and%20evolution&journal=PLoS%20Genet.&doi=10.1371%2Fjournal.pgen.1000249&volume=4&publication_year=2008&author=Hasin%2CY
- How much does https://doi.org/10.1038%2Fng2123 pull in monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Diet%20and%20the%20evolution%20of%20human%20amylase%20gene%20copy%20number%20variation&journal=Nat.%20Genet.&doi=10.1038%2Fng2123&volume=39&pages=1256-1260&publication_year=2007&author=Perry%2CGH earn?
- What is the earnings of https://doi.org/10.1038%2Fng.686?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Association%20analyses%20of%20249%2C796%20individuals%20reveal%2018%20new%20loci%20associated%20with%20body%20mass%20index&journal=Nat.%20Genet.&doi=10.1038%2Fng.686&volume=42&pages=937-948&publication_year=2010&author=Speliotes%2CEK make?
- How much revenue does https://doi.org/10.1126%2Fscience.1138659 generate?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=Strong%20association%20of%20de%20novo%20copy%20number%20mutations%20with%20autism&journal=Science&doi=10.1126%2Fscience.1138659&volume=316&pages=445-449&publication_year=2007&author=Sebat%2CJ?
- What is the earnings of https://doi.org/10.1038%2Fnature08822?
- How much does http://scholar.google.com/scholar_lookup?&title=The%20landscape%20of%20somatic%20copy-number%20alteration%20across%20human%20cancers&journal=Nature&doi=10.1038%2Fnature08822&volume=463&pages=899-905&publication_year=2010&author=Beroukhim%2CR generate monthly?
- Earnings of https://doi.org/10.1038%2Fnature08768
- How much profit does http://scholar.google.com/scholar_lookup?&title=Signatures%20of%20mutation%20and%20selection%20in%20the%20cancer%20genome&journal=Nature&doi=10.1038%2Fnature08768&volume=463&pages=893-898&publication_year=2010&author=Bignell%2CGR generate?
- Explore the financials of https://doi.org/10.1126%2Fscitranslmed.3000611
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Genomic%20architecture%20characterizes%20tumor%20progression%20paths%20and%20fate%20in%20breast%20cancer%20patients&journal=Sci.%20Transl.%20Med.&doi=10.1126%2Fscitranslmed.3000611&volume=2&publication_year=2010&author=Russnes%2CHG
- What's https://doi.org/10.2217%2Ffon.10.56's gross income?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=DNA%20amplifications%20in%20breast%20cancer%3A%20genotypic-phenotypic%20correlations&journal=Future%20Oncol.&doi=10.2217%2Ffon.10.56&volume=6&pages=967-984&publication_year=2010&author=Shiu%2CKK&author=Natrajan%2CR&author=Geyer%2CFC&author=Ashworth%2CA&author=Reis-Filho%2CJS produce monthly?
- https://doi.org/10.1016%2Fj.drudis.2008.06.007's total income per month
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=The%20array%20CGH%20and%20its%20clinical%20applications&journal=Drug%20Discov.%20Today&doi=10.1016%2Fj.drudis.2008.06.007&volume=13&pages=760-770&publication_year=2008&author=Shinawi%2CM&author=Cheung%2CSW?
- Monthly income for https://doi.org/10.1038%2Fnrc2771
- How much does http://scholar.google.com/scholar_lookup?&title=A%20census%20of%20amplified%20and%20overexpressed%20human%20cancer%20genes&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc2771&volume=10&pages=59-64&publication_year=2010&author=Santarius%2CT&author=Shipley%2CJ&author=Brewer%2CD&author=Stratton%2CMR&author=Cooper%2CCS gross monthly?
- How much revenue does https://doi.org/10.1038%2Fng1569 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=Array%20comparative%20genomic%20hybridization%20and%20its%20applications%20in%20cancer&journal=Nat.%20Genet.&doi=10.1038%2Fng1569&volume=37&issue=suppl.&pages=S11-17&publication_year=2005&author=Pinkel%2CD&author=Albertson%2CDG earn?
- How profitable is https://doi.org/10.1002%2Fgcc.20797?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Clonal%20heterogeneity%20in%20childhood%20myelodysplastic%20syndromes%E2%80%94challenge%20for%20the%20detection%20of%20chromosomal%20imbalances%20by%20array-CGH&journal=Genes%20Chromosomes%20Cancer&doi=10.1002%2Fgcc.20797&volume=49&pages=885-900&publication_year=2010&author=Praulich%2CI?
- Discover the revenue of https://doi.org/10.1038%2Fnrg2626
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Sequencing%20technologies%E2%80%94the%20next%20generation&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2626&volume=11&pages=31-46&publication_year=2010&author=Metzker%2CML
- Check the income stats for https://doi.org/10.1016%2Fj.tig.2007.12.007
- How much profit does http://scholar.google.com/scholar_lookup?&title=The%20impact%20of%20next-generation%20sequencing%20technology%20on%20genetics&journal=Trends%20Genet.&doi=10.1016%2Fj.tig.2007.12.007&volume=24&pages=133-141&publication_year=2008&author=Mardis%2CER generate?
- https://doi.org/10.1038%2Fnrg2841 income
- How much income does http://scholar.google.com/scholar_lookup?&title=Advances%20in%20understanding%20cancer%20genomes%20through%20second-generation%20sequencing&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2841&volume=11&pages=685-696&publication_year=2010&author=Meyerson%2CM&author=Gabriel%2CS&author=Getz%2CG have?
- How much profit does https://doi.org/10.1038%2Fnmeth.1276 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=High-resolution%20mapping%20of%20copy-number%20alterations%20with%20massively%20parallel%20sequencing&journal=Nat.%20Methods&doi=10.1038%2Fnmeth.1276&volume=6&pages=99-103&publication_year=2009&author=Chiang%2CDY rake in every month?
- Financial intake of https://doi.org/10.1038%2Fng.437
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Personalized%20copy%20number%20and%20segmental%20duplication%20maps%20using%20next-generation%20sequencing&journal=Nat.%20Genet.&doi=10.1038%2Fng.437&volume=41&pages=1061-1067&publication_year=2009&author=Alkan%2CC bring in?
- What's the financial outcome of https://doi.org/10.1038%2Fnature08489?
- Revenue of http://scholar.google.com/scholar_lookup?&title=Mutational%20evolution%20in%20a%20lobular%20breast%20tumour%20profiled%20at%20single%20nucleotide%20resolution&journal=Nature&doi=10.1038%2Fnature08489&volume=461&pages=809-813&publication_year=2009&author=Shah%2CSP
- How much revenue does https://doi.org/10.1038%2Fnature08989 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=Genome%20remodelling%20in%20a%20basal-like%20breast%20cancer%20metastasis%20and%20xenograft&journal=Nature&doi=10.1038%2Fnature08989&volume=464&pages=999-1005&publication_year=2010&author=Ding%2CL bring in each month?
- What's the income generated by https://doi.org/10.1038%2Fnature09460 each month?
- How much income does http://scholar.google.com/scholar_lookup?&title=The%20patterns%20and%20dynamics%20of%20genomic%20instability%20in%20metastatic%20pancreatic%20cancer&journal=Nature&doi=10.1038%2Fnature09460&volume=467&pages=1109-1113&publication_year=2010&author=Campbell%2CPJ have?
- Monthly income for https://doi.org/10.1038%2Fnature09515
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Distant%20metastasis%20occurs%20late%20during%20the%20genetic%20evolution%20of%20pancreatic%20cancer&journal=Nature&doi=10.1038%2Fnature09515&volume=467&pages=1114-1117&publication_year=2010&author=Yachida%2CS?
- Learn how profitable https://doi.org/10.1038%2Fnature09650 is on a monthly basis
- How much does http://scholar.google.com/scholar_lookup?&title=Genetic%20variegation%20of%20clonal%20architecture%20and%20propagating%20cells%20in%20leukaemia&journal=Nature&doi=10.1038%2Fnature09650&volume=469&pages=356-361&publication_year=2011&author=Anderson%2CK make?
- What's the financial intake of https://doi.org/10.1038%2Fnature09807?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Tumour%20evolution%20inferred%20by%20single-cell%20sequencing&journal=Nature&doi=10.1038%2Fnature09807&volume=472&pages=90-94&publication_year=2011&author=Navin%2CN?
- https://link.springer.com/doi/10.1186/gb-2009-10-3-r25's financial summary
- Earnings of http://scholar.google.com/scholar_lookup?&title=Ultrafast%20and%20memory-efficient%20alignment%20of%20short%20DNA%20sequences%20to%20the%20human%20genome&journal=Genome%20Biol.&doi=10.1186%2Fgb-2009-10-3-r25&volume=10&publication_year=2009&author=Langmead%2CB&author=Trapnell%2CC&author=Pop%2CM&author=Salzberg%2CSL
- What's the profit of https://doi.org/10.1093%2Fbioinformatics%2Fbtp352?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=The%20Sequence%20Alignment%2FMap%20format%20and%20SAMtools&journal=Bioinformatics&doi=10.1093%2Fbioinformatics%2Fbtp352&volume=15&pages=2078-2079&publication_year=2009&author=Li%2CH
- Learn how profitable https://doi.org/10.1093%2Fbioinformatics%2Fbtl646 is on a monthly basis
- How much does http://scholar.google.com/scholar_lookup?&title=A%20faster%20cicular%20binary%20segmentation%20algorithm%20for%20the%20analysis%20of%20array%20CGH%20data&journal=Bioinformatics&doi=10.1093%2Fbioinformatics%2Fbtl646&volume=23&pages=657-63&publication_year=2007&author=Venkatraman%2CES&author=Olshen%2CAB rake in every month?
- Get to know what's the income of https://doi.org/10.1002%2Fcyto.1171
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Doublet%20discrimination%20in%20DNA%20cell-cycle%20analysis&journal=Cytometry&doi=10.1002%2Fcyto.1171&volume=46&pages=296-306&publication_year=2001&author=Wersto%2CRP?
- How much revenue does https://doi.org/10.1038%2Fsj.cdd.4401161 bring in?
- How much does http://scholar.google.com/scholar_lookup?&title=Degradation%20of%20chromosomal%20DNA%20during%20apoptosis&journal=Cell%20Death%20Differ&doi=10.1038%2Fsj.cdd.4401161&volume=10&pages=108-116&publication_year=2003&author=Nagata%2CS&author=Nagase%2CH&author=Kawane%2CK&author=Mukae%2CN&author=Fukuyama%2CH gross monthly?
- Revenue of https://doi.org/10.1016%2Fj.cell.2010.11.055
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Massive%20genomic%20rearragement%20acquired%20in%20a%20single%20catastrophic%20event%20during%20cancer%20development&journal=Cell&doi=10.1016%2Fj.cell.2010.11.055&volume=144&pages=27-40&publication_year=2011&author=Stephans%2CPJ produce monthly?
- See how much https://citation-needed.springer.com/v2/references/10.1038/nprot.2012.039?format=refman&flavour=references makes per month
- What's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Timour%20Baslan?
- How much cash flow does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Timour%20Baslan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have monthly?
- Income figures for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jude%20Kendall
- How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jude%20Kendall%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
- Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Linda%20Rodgers
- See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Linda%20Rodgers%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Hilary%20Cox make?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Hilary%20Cox%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
- How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mike%20Riggs generate?
- What is the monthly revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mike%20Riggs%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much income does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Asya%20Stepansky have?
- How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Asya%20Stepansky%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jennifer%20Troge produce monthly?
- How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jennifer%20Troge%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kandasamy%20Ravi?
- How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kandasamy%20Ravi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- What's the revenue for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Diane%20Esposito?
- How much cash flow does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Diane%20Esposito%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have monthly?
- What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=B%20Lakshmi?
- What's the profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22B%20Lakshmi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Michael%20Wigler income
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Michael%20Wigler%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
- How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Nicholas%20Navin make?
- How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Nicholas%20Navin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- What's the financial outcome of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=James%20Hicks?
- How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22James%20Hicks%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- What's the revenue for https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM448_ESM.eps?
- What's the financial gain of https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM449_ESM.zip?
- How much cash flow does https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM450_ESM.zip have monthly?
- How much revenue does https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM451_ESM.txt generate?
- How much does https://s100.copyright.com/AppDispatchServlet?title=Genome-wide%20copy%20number%20analysis%20of%20single%20cells&author=Timour%20Baslan%20et%20al&contentID=10.1038%2Fnprot.2012.039©right=Springer%20Nature%20Limited&publication=1754-2189&publicationDate=2012-05-03&publisherName=SpringerNature&orderBeanReset=true pull in?
- How much does https://citation-needed.springer.com/v2/references/10.1038/nprot.2012.039?format=refman&flavour=citation pull in?
- How much profit does https://doi.org/10.1038/s41467-023-40378-8 make?
- What's the total monthly financial gain of https://doi.org/10.1007/s10577-023-09740-w?
- How much profit does https://doi.org/10.1186/s12920-022-01264-2 make?
- Find out how much https://doi.org/10.1186/s40478-022-01452-2 earns monthly
- How much income does https://doi.org/10.1038/s41588-022-01180-2 have?
- Explore the financials of https://www.protocols.io/
- Revenue of https://www.natureindex.com/
- How much income does http://www.naturechina.com have?
- How much income does https://www.natureasia.com/ja-jp have?
Analytics and Tracking {๐}
- Google Tag Manager
Libraries {๐}
- Foundation
- Prism.js
- Zoom.js
Emails and Hosting {โ๏ธ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {๐ฆ}
- Crossref