
NATURE . COM {
}
Title:
Genome-wide copy number analysis of single cells | Nature Protocols
Description:
Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells in which information regarding genetic heterogeneity is lost. Here we present a protocol that allows for the genome-wide copy number analysis of single nuclei isolated from mixed populations of cells. Single-nucleus sequencing (SNS), combines flow sorting of single nuclei on the basis of DNA content and whole-genome amplification (WGA); this is followed by next-generation sequencing to quantize genomic intervals in a genome-wide manner. Multiplexing of single cells is discussed. In addition, we outline informatic approaches that correct for biases inherent in the WGA procedure and allow for accurate determination of copy number profiles. All together, the protocol takes โผ3 d from flow cytometry to sequence-ready DNA libraries.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {๐}
- Education
- Science
- Technology & Computing
Content Management System {๐}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {๐}
What is the average monthly size of nature.com audience?
๐ Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {๐ธ}
Display Ads {๐ฏ}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {๐ฐ}
Display Ads {๐ฏ}
$63,100 per month
Our estimates place Nature.com's monthly online earnings from display ads at $42,042 to $115,616.
Keywords {๐}
article, google, scholar, nature, cas, cancer, data, copy, number, sequencing, nat, single, access, content, genet, supplementary, analysis, human, genome, research, cookies, cells, methods, dna, evolution, privacy, information, genomewide, variation, genomic, breast, cell, texas, protocols, protocol, published, baslan, wigler, nicholas, navin, hicks, genetic, open, rev, singlecell, bioinformatics, development, usa, advertising, subscribe,
Topics {โ๏ธ}
sequence-ready dna libraries nature portfolio permissions reprints privacy policy body mass index sequence alignment/map format advertising cancer research somatic copy-number alteration social media single-cell genome sequencing institutional subscriptions read author information authors hbv-driven hepatocellular carcinoma childhood myelodysplastic syndromesโchallenge input-program-output labels dna cell-cycle analysis copy number variants nature 463 nature 461 nature 464 nature 467 nature 469 nature 472 nature author correspondence single-cell sequencing genome-wide association testing springerlink instant access copy number profiles high-resolution mapping copy-number alterations personalized copy number copy number estimation joint copy number copy number determination cancer development permissions breast cancer patients single-nucleus sequencing article initially published single nucleotide resolution technology development cold spring harbor change 25 february 2016 human genome genome-wide manner massively parallel sequencing single catastrophic event
Schema {๐บ๏ธ}
WebPage:
mainEntity:
headline:Genome-wide copy number analysis of single cells
description:Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells in which information regarding genetic heterogeneity is lost. Here we present a protocol that allows for the genome-wide copy number analysis of single nuclei isolated from mixed populations of cells. Single-nucleus sequencing (SNS), combines flow sorting of single nuclei on the basis of DNA content and whole-genome amplification (WGA); this is followed by next-generation sequencing to quantize genomic intervals in a genome-wide manner. Multiplexing of single cells is discussed. In addition, we outline informatic approaches that correct for biases inherent in the WGA procedure and allow for accurate determination of copy number profiles. All together, the protocol takes รขยยผ3 d from flow cytometry to sequence-ready DNA libraries.
datePublished:2012-05-03T00:00:00Z
dateModified:2016-02-24T00:00:00Z
pageStart:1024
pageEnd:1041
sameAs:https://doi.org/10.1038/nprot.2012.039
keywords:
Bioinformatics
Library construction
Structural variation
Whole genome amplification
Life Sciences
general
Biological Techniques
Analytical Chemistry
Microarrays
Computational Biology/Bioinformatics
Organic Chemistry
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figa_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figb_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figc_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figd_HTML.gif
isPartOf:
name:Nature Protocols
issn:
1750-2799
1754-2189
volumeNumber:7
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Timour Baslan
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
type:Organization
type:Person
name:Jude Kendall
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Linda Rodgers
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Hilary Cox
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Mike Riggs
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Asya Stepansky
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Jennifer Troge
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Kandasamy Ravi
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Diane Esposito
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:B Lakshmi
affiliation:
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
type:Organization
type:Person
name:Michael Wigler
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Nicholas Navin
affiliation:
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:James Hicks
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Genome-wide copy number analysis of single cells
description:Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells in which information regarding genetic heterogeneity is lost. Here we present a protocol that allows for the genome-wide copy number analysis of single nuclei isolated from mixed populations of cells. Single-nucleus sequencing (SNS), combines flow sorting of single nuclei on the basis of DNA content and whole-genome amplification (WGA); this is followed by next-generation sequencing to quantize genomic intervals in a genome-wide manner. Multiplexing of single cells is discussed. In addition, we outline informatic approaches that correct for biases inherent in the WGA procedure and allow for accurate determination of copy number profiles. All together, the protocol takes รขยยผ3 d from flow cytometry to sequence-ready DNA libraries.
datePublished:2012-05-03T00:00:00Z
dateModified:2016-02-24T00:00:00Z
pageStart:1024
pageEnd:1041
sameAs:https://doi.org/10.1038/nprot.2012.039
keywords:
Bioinformatics
Library construction
Structural variation
Whole genome amplification
Life Sciences
general
Biological Techniques
Analytical Chemistry
Microarrays
Computational Biology/Bioinformatics
Organic Chemistry
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figa_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figb_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figc_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_Article_BFnprot2012039_Figd_HTML.gif
isPartOf:
name:Nature Protocols
issn:
1750-2799
1754-2189
volumeNumber:7
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Timour Baslan
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
type:Organization
type:Person
name:Jude Kendall
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Linda Rodgers
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Hilary Cox
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Mike Riggs
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Asya Stepansky
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Jennifer Troge
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Kandasamy Ravi
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Diane Esposito
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:B Lakshmi
affiliation:
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
type:Organization
type:Person
name:Michael Wigler
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
type:Person
name:Nicholas Navin
affiliation:
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:James Hicks
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature Protocols
issn:
1750-2799
1754-2189
volumeNumber:7
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Timour Baslan
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Molecular and Cellular Biology Program, Stony Brook University
address:
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
type:PostalAddress
type:Organization
name:Jude Kendall
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Linda Rodgers
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Hilary Cox
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Mike Riggs
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Asya Stepansky
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Jennifer Troge
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Kandasamy Ravi
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Diane Esposito
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:B Lakshmi
affiliation:
name:Ontario Institute for Cancer Research, Toronto
address:
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
type:PostalAddress
type:Organization
name:Michael Wigler
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
name:Nicholas Navin
affiliation:
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:University of Texas MD Anderson Cancer Center
address:
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:James Hicks
affiliation:
name:Cold Spring Harbor Laboratory
address:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Ontario Institute for Cancer Research, Toronto, Ontario, Canada
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
name:Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, USA
name:Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, USA
name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {๐}(105)
- What's the financial gain of https://doi.org/10.1038/nprot0316.616b?
- How much does https://link.springer.com/article/10.1038/nprot.2012.039?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle gross monthly?
- Discover the revenue of http://www.ncbi.nlm.nih.gov/sra?term=SRR054616
- How much revenue does https://doi.org/10.1038%2Fnrg2149 produce monthly?
- Find out how much http://scholar.google.com/scholar_lookup?&title=Copy%20number%20variants%20and%20genetic%20traits%3A%20closer%20to%20the%20resolution%20of%20phenotypic%20to%20genotypic%20variability&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2149&volume=8&pages=639-646&publication_year=2007&author=Beckmann%2CJS&author=Estivill%2CX&author=Antonarakis%2CSE earns monthly
- Discover the revenue of https://doi.org/10.1371%2Fjournal.pgen.1000249
- How profitable is http://scholar.google.com/scholar_lookup?&title=High-resolution%20copy-number%20variation%20map%20reflects%20human%20olfactory%20receptor%20diversity%20and%20evolution&journal=PLoS%20Genet.&doi=10.1371%2Fjournal.pgen.1000249&volume=4&publication_year=2008&author=Hasin%2CY?
- What's the income generated by https://doi.org/10.1038%2Fng2123 each month?
- How much does http://scholar.google.com/scholar_lookup?&title=Diet%20and%20the%20evolution%20of%20human%20amylase%20gene%20copy%20number%20variation&journal=Nat.%20Genet.&doi=10.1038%2Fng2123&volume=39&pages=1256-1260&publication_year=2007&author=Perry%2CGH gross monthly?
- How much does https://doi.org/10.1038%2Fng.686 generate monthly?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Association%20analyses%20of%20249%2C796%20individuals%20reveal%2018%20new%20loci%20associated%20with%20body%20mass%20index&journal=Nat.%20Genet.&doi=10.1038%2Fng.686&volume=42&pages=937-948&publication_year=2010&author=Speliotes%2CEK have monthly?
- What's the monthly money flow for https://doi.org/10.1126%2Fscience.1138659?
- Income figures for http://scholar.google.com/scholar_lookup?&title=Strong%20association%20of%20de%20novo%20copy%20number%20mutations%20with%20autism&journal=Science&doi=10.1126%2Fscience.1138659&volume=316&pages=445-449&publication_year=2007&author=Sebat%2CJ
- How much profit is https://doi.org/10.1038%2Fnature08822 making per month?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=The%20landscape%20of%20somatic%20copy-number%20alteration%20across%20human%20cancers&journal=Nature&doi=10.1038%2Fnature08822&volume=463&pages=899-905&publication_year=2010&author=Beroukhim%2CR
- Profit of https://doi.org/10.1038%2Fnature08768
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Signatures%20of%20mutation%20and%20selection%20in%20the%20cancer%20genome&journal=Nature&doi=10.1038%2Fnature08768&volume=463&pages=893-898&publication_year=2010&author=Bignell%2CGR?
- What are the earnings of https://doi.org/10.1126%2Fscitranslmed.3000611?
- Find out how much http://scholar.google.com/scholar_lookup?&title=Genomic%20architecture%20characterizes%20tumor%20progression%20paths%20and%20fate%20in%20breast%20cancer%20patients&journal=Sci.%20Transl.%20Med.&doi=10.1126%2Fscitranslmed.3000611&volume=2&publication_year=2010&author=Russnes%2CHG earns monthly
- How much does https://doi.org/10.2217%2Ffon.10.56 bring in each month?
- How much does http://scholar.google.com/scholar_lookup?&title=DNA%20amplifications%20in%20breast%20cancer%3A%20genotypic-phenotypic%20correlations&journal=Future%20Oncol.&doi=10.2217%2Ffon.10.56&volume=6&pages=967-984&publication_year=2010&author=Shiu%2CKK&author=Natrajan%2CR&author=Geyer%2CFC&author=Ashworth%2CA&author=Reis-Filho%2CJS pull in monthly?
- Financial intake of https://doi.org/10.1016%2Fj.drudis.2008.06.007
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=The%20array%20CGH%20and%20its%20clinical%20applications&journal=Drug%20Discov.%20Today&doi=10.1016%2Fj.drudis.2008.06.007&volume=13&pages=760-770&publication_year=2008&author=Shinawi%2CM&author=Cheung%2CSW?
- https://doi.org/10.1038%2Fnrc2771's financial summary
- How much does http://scholar.google.com/scholar_lookup?&title=A%20census%20of%20amplified%20and%20overexpressed%20human%20cancer%20genes&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc2771&volume=10&pages=59-64&publication_year=2010&author=Santarius%2CT&author=Shipley%2CJ&author=Brewer%2CD&author=Stratton%2CMR&author=Cooper%2CCS generate monthly?
- https://doi.org/10.1038%2Fng1569's total income per month
- How much money does http://scholar.google.com/scholar_lookup?&title=Array%20comparative%20genomic%20hybridization%20and%20its%20applications%20in%20cancer&journal=Nat.%20Genet.&doi=10.1038%2Fng1569&volume=37&issue=suppl.&pages=S11-17&publication_year=2005&author=Pinkel%2CD&author=Albertson%2CDG generate?
- How much does https://doi.org/10.1002%2Fgcc.20797 earn?
- How much money does http://scholar.google.com/scholar_lookup?&title=Clonal%20heterogeneity%20in%20childhood%20myelodysplastic%20syndromes%E2%80%94challenge%20for%20the%20detection%20of%20chromosomal%20imbalances%20by%20array-CGH&journal=Genes%20Chromosomes%20Cancer&doi=10.1002%2Fgcc.20797&volume=49&pages=885-900&publication_year=2010&author=Praulich%2CI generate?
- Revenue of https://doi.org/10.1038%2Fnrg2626
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Sequencing%20technologies%E2%80%94the%20next%20generation&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2626&volume=11&pages=31-46&publication_year=2010&author=Metzker%2CML
- What's the income of https://doi.org/10.1016%2Fj.tig.2007.12.007?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=The%20impact%20of%20next-generation%20sequencing%20technology%20on%20genetics&journal=Trends%20Genet.&doi=10.1016%2Fj.tig.2007.12.007&volume=24&pages=133-141&publication_year=2008&author=Mardis%2CER
- https://doi.org/10.1038%2Fnrg2841 income
- Financial intake of http://scholar.google.com/scholar_lookup?&title=Advances%20in%20understanding%20cancer%20genomes%20through%20second-generation%20sequencing&journal=Nat.%20Rev.%20Genet.&doi=10.1038%2Fnrg2841&volume=11&pages=685-696&publication_year=2010&author=Meyerson%2CM&author=Gabriel%2CS&author=Getz%2CG
- Monthly income for https://doi.org/10.1038%2Fnmeth.1276
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=High-resolution%20mapping%20of%20copy-number%20alterations%20with%20massively%20parallel%20sequencing&journal=Nat.%20Methods&doi=10.1038%2Fnmeth.1276&volume=6&pages=99-103&publication_year=2009&author=Chiang%2CDY?
- What's the income generated by https://doi.org/10.1038%2Fng.437 each month?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Personalized%20copy%20number%20and%20segmental%20duplication%20maps%20using%20next-generation%20sequencing&journal=Nat.%20Genet.&doi=10.1038%2Fng.437&volume=41&pages=1061-1067&publication_year=2009&author=Alkan%2CC
- https://doi.org/10.1038%2Fnature08489's revenue stream
- How profitable is http://scholar.google.com/scholar_lookup?&title=Mutational%20evolution%20in%20a%20lobular%20breast%20tumour%20profiled%20at%20single%20nucleotide%20resolution&journal=Nature&doi=10.1038%2Fnature08489&volume=461&pages=809-813&publication_year=2009&author=Shah%2CSP?
- How much money does https://doi.org/10.1038%2Fnature08989 make?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Genome%20remodelling%20in%20a%20basal-like%20breast%20cancer%20metastasis%20and%20xenograft&journal=Nature&doi=10.1038%2Fnature08989&volume=464&pages=999-1005&publication_year=2010&author=Ding%2CL generate?
- What's the monthly money flow for https://doi.org/10.1038%2Fnature09460?
- How much does http://scholar.google.com/scholar_lookup?&title=The%20patterns%20and%20dynamics%20of%20genomic%20instability%20in%20metastatic%20pancreatic%20cancer&journal=Nature&doi=10.1038%2Fnature09460&volume=467&pages=1109-1113&publication_year=2010&author=Campbell%2CPJ make?
- Get to know what's the income of https://doi.org/10.1038%2Fnature09515
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Distant%20metastasis%20occurs%20late%20during%20the%20genetic%20evolution%20of%20pancreatic%20cancer&journal=Nature&doi=10.1038%2Fnature09515&volume=467&pages=1114-1117&publication_year=2010&author=Yachida%2CS?
- How much does https://doi.org/10.1038%2Fnature09650 pull in?
- Find out how much http://scholar.google.com/scholar_lookup?&title=Genetic%20variegation%20of%20clonal%20architecture%20and%20propagating%20cells%20in%20leukaemia&journal=Nature&doi=10.1038%2Fnature09650&volume=469&pages=356-361&publication_year=2011&author=Anderson%2CK earns monthly
- What's the income generated by https://doi.org/10.1038%2Fnature09807 each month?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Tumour%20evolution%20inferred%20by%20single-cell%20sequencing&journal=Nature&doi=10.1038%2Fnature09807&volume=472&pages=90-94&publication_year=2011&author=Navin%2CN?
- Discover the revenue of https://link.springer.com/doi/10.1186/gb-2009-10-3-r25
- How much does http://scholar.google.com/scholar_lookup?&title=Ultrafast%20and%20memory-efficient%20alignment%20of%20short%20DNA%20sequences%20to%20the%20human%20genome&journal=Genome%20Biol.&doi=10.1186%2Fgb-2009-10-3-r25&volume=10&publication_year=2009&author=Langmead%2CB&author=Trapnell%2CC&author=Pop%2CM&author=Salzberg%2CSL rake in every month?
- Monthly income for https://doi.org/10.1093%2Fbioinformatics%2Fbtp352
- http://scholar.google.com/scholar_lookup?&title=The%20Sequence%20Alignment%2FMap%20format%20and%20SAMtools&journal=Bioinformatics&doi=10.1093%2Fbioinformatics%2Fbtp352&volume=15&pages=2078-2079&publication_year=2009&author=Li%2CH income
- What are the total earnings of https://doi.org/10.1093%2Fbioinformatics%2Fbtl646?
- How much does http://scholar.google.com/scholar_lookup?&title=A%20faster%20cicular%20binary%20segmentation%20algorithm%20for%20the%20analysis%20of%20array%20CGH%20data&journal=Bioinformatics&doi=10.1093%2Fbioinformatics%2Fbtl646&volume=23&pages=657-63&publication_year=2007&author=Venkatraman%2CES&author=Olshen%2CAB earn?
- How much does https://doi.org/10.1002%2Fcyto.1171 gross monthly?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Doublet%20discrimination%20in%20DNA%20cell-cycle%20analysis&journal=Cytometry&doi=10.1002%2Fcyto.1171&volume=46&pages=296-306&publication_year=2001&author=Wersto%2CRP?
- How much does https://doi.org/10.1038%2Fsj.cdd.4401161 earn?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Degradation%20of%20chromosomal%20DNA%20during%20apoptosis&journal=Cell%20Death%20Differ&doi=10.1038%2Fsj.cdd.4401161&volume=10&pages=108-116&publication_year=2003&author=Nagata%2CS&author=Nagase%2CH&author=Kawane%2CK&author=Mukae%2CN&author=Fukuyama%2CH?
- https://doi.org/10.1016%2Fj.cell.2010.11.055 income
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Massive%20genomic%20rearragement%20acquired%20in%20a%20single%20catastrophic%20event%20during%20cancer%20development&journal=Cell&doi=10.1016%2Fj.cell.2010.11.055&volume=144&pages=27-40&publication_year=2011&author=Stephans%2CPJ?
- How much cash flow does https://citation-needed.springer.com/v2/references/10.1038/nprot.2012.039?format=refman&flavour=references have monthly?
- Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Timour%20Baslan
- What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Timour%20Baslan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jude%20Kendall?
- What are the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jude%20Kendall%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Linda%20Rodgers's financial summary
- Profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Linda%20Rodgers%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much income does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Hilary%20Cox have?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Hilary%20Cox%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
- How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mike%20Riggs making per month?
- Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mike%20Riggs%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
- How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Asya%20Stepansky make?
- See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Asya%20Stepansky%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
- How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jennifer%20Troge making per month?
- Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jennifer%20Troge%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
- Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kandasamy%20Ravi
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kandasamy%20Ravi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Diane%20Esposito net monthly?
- What's the monthly money flow for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Diane%20Esposito%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=B%20Lakshmi?
- Revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22B%20Lakshmi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much income is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Michael%20Wigler earning monthly?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Michael%20Wigler%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
- How profitable is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Nicholas%20Navin?
- Learn about the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Nicholas%20Navin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=James%20Hicks making per month?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22James%20Hicks%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en rake in every month?
- https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM448_ESM.eps income
- https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM449_ESM.zip's total income per month
- What's the profit of https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM450_ESM.zip?
- What's the monthly income of https://static-content.springer.com/esm/art%3A10.1038%2Fnprot.2012.039/MediaObjects/41596_2012_BFnprot2012039_MOESM451_ESM.txt?
- What's the monthly money flow for https://s100.copyright.com/AppDispatchServlet?title=Genome-wide%20copy%20number%20analysis%20of%20single%20cells&author=Timour%20Baslan%20et%20al&contentID=10.1038%2Fnprot.2012.039©right=Springer%20Nature%20Limited&publication=1754-2189&publicationDate=2012-05-03&publisherName=SpringerNature&orderBeanReset=true?
- What's the revenue for https://citation-needed.springer.com/v2/references/10.1038/nprot.2012.039?format=refman&flavour=citation?
- Earnings of https://doi.org/10.1038/s41467-023-40378-8
- How much does https://doi.org/10.1007/s10577-023-09740-w pull in?
- How much income is https://doi.org/10.1186/s12920-022-01264-2 earning monthly?
- What are the earnings of https://doi.org/10.1186/s40478-022-01452-2?
- How much does https://doi.org/10.1038/s41588-022-01180-2 gross monthly?
- How much profit is https://www.protocols.io/ making per month?
- How profitable is https://www.natureindex.com/?
- Profit of http://www.naturechina.com
- How much does https://www.natureasia.com/ja-jp earn?
Analytics and Tracking {๐}
- Google Tag Manager
Libraries {๐}
- Foundation
- Prism.js
- Zoom.js
Emails and Hosting {โ๏ธ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {๐ฆ}
- Crossref