
NATURE . COM {
}
Title:
Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cells | Nature Immunology
Description:
Interleukin 17 (IL-17)–producing CD4+ helper T cells (TH-17 cells) have been linked to host defense and autoimmune diseases. In mice, the differentiation of TH-17 cells requires transforming growth factor-β and IL-6 and the transcription factor RORγt. We report here that for human naive CD4+ T cells, RORγt expression and TH-17 polarization were induced by IL-1β and enhanced by IL-6 but were suppressed by transforming growth factor-β and IL-12. Monocytes and conventional dendritic cells, but not monocyte-derived dendritic cells activated by microbial stimuli, efficiently induced TH-17 priming, and this function correlated with antigen-presenting cell production of IL-1β and IL-6 but not IL-12. Our results identify cytokines, antigen-presenting cells and microbial products that promote the polarization of human TH-17 cells and emphasize an important difference in the requirements for the differentiation of TH-17 cells in humans and mice.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {📚}
- Science
- Education
- Social Networks
Content Management System {📝}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of nature.com audience?
🌆 Monumental Traffic: 20M - 50M visitors per month
Based on our best estimate, this website will receive around 42,554,915 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {💸}
Display Ads {🎯}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {💰}
Display Ads {🎯}
$536,300 per month
Our estimates place Nature.com's monthly online earnings from display ads at $357,503 to $983,134.
Keywords {🔍}
article, google, scholar, cas, cells, nature, interleukin, immunol, nat, differentiation, human, helper, cell, access, med, content, immunology, factor, dendritic, exp, transforming, growth, producing, production, arthritis, development, cookies, factorβ, autoimmune, mice, receptor, inflammatory, immunity, research, privacy, acostarodriguez, ilproducing, expression, monocytes, activation, inflammation, cytokine, essential, data, information, journal, lanzavecchia, sallusto, distinct, open,
Topics {✒️}
nature portfolio permissions reprints privacy policy granulocyte/macrophage colony-stimulating factor author information authors advertising transforming growth factor-β social media research nature 445 nature 441 nature antonio lanzavecchia & federica sallusto il-17-secreting t-helper phenotype nf-κb signal pathway acute tnbs-induced colitis hu-pbl-scid mice data protection content development personal data springerlink instant access interleukin-1β converting enzyme il-1 receptor antagonist lung cxc chemokine antigen-presenting cell production permissions spontaneous development il-18-stimulated gadd45β required transcription factor rorγt article acosta-rodriguez il-23-mediated il-17 production inflammatory bowel disease ifn-γ production cell-mediated colitis mediate autoimmune encephalomyelitis card9-dependent coupling remote control mechanism privacy competing financial interests tlr activation triggers clinical immunology il-17 receptor signaling joint autoimmune inflammation inflammatory chemokine transport issue learn helmut horten foundation pathogenic effector th17 conventional dendritic cells antigen-presenting cells dendritic langerhans cells
Schema {🗺️}
WebPage:
mainEntity:
headline:Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17âproducing human T helper cells
description:Interleukin 17 (IL-17)âproducing CD4+ helper T cells (TH-17 cells) have been linked to host defense and autoimmune diseases. In mice, the differentiation of TH-17 cells requires transforming growth factor-β and IL-6 and the transcription factor RORγt. We report here that for human naive CD4+ T cells, RORγt expression and TH-17 polarization were induced by IL-1β and enhanced by IL-6 but were suppressed by transforming growth factor-β and IL-12. Monocytes and conventional dendritic cells, but not monocyte-derived dendritic cells activated by microbial stimuli, efficiently induced TH-17 priming, and this function correlated with antigen-presenting cell production of IL-1β and IL-6 but not IL-12. Our results identify cytokines, antigen-presenting cells and microbial products that promote the polarization of human TH-17 cells and emphasize an important difference in the requirements for the differentiation of TH-17 cells in humans and mice.
datePublished:2007-08-05T00:00:00Z
dateModified:2007-08-05T00:00:00Z
pageStart:942
pageEnd:949
sameAs:https://doi.org/10.1038/ni1496
keywords:
Biomedicine
general
Immunology
Infectious Diseases
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig6_HTML.jpg
isPartOf:
name:Nature Immunology
issn:
1529-2916
1529-2908
volumeNumber:8
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Eva V Acosta-Rodriguez
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Giorgio Napolitani
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
type:Person
name:Antonio Lanzavecchia
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
type:Person
name:Federica Sallusto
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17âproducing human T helper cells
description:Interleukin 17 (IL-17)âproducing CD4+ helper T cells (TH-17 cells) have been linked to host defense and autoimmune diseases. In mice, the differentiation of TH-17 cells requires transforming growth factor-β and IL-6 and the transcription factor RORγt. We report here that for human naive CD4+ T cells, RORγt expression and TH-17 polarization were induced by IL-1β and enhanced by IL-6 but were suppressed by transforming growth factor-β and IL-12. Monocytes and conventional dendritic cells, but not monocyte-derived dendritic cells activated by microbial stimuli, efficiently induced TH-17 priming, and this function correlated with antigen-presenting cell production of IL-1β and IL-6 but not IL-12. Our results identify cytokines, antigen-presenting cells and microbial products that promote the polarization of human TH-17 cells and emphasize an important difference in the requirements for the differentiation of TH-17 cells in humans and mice.
datePublished:2007-08-05T00:00:00Z
dateModified:2007-08-05T00:00:00Z
pageStart:942
pageEnd:949
sameAs:https://doi.org/10.1038/ni1496
keywords:
Biomedicine
general
Immunology
Infectious Diseases
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_Article_BFni1496_Fig6_HTML.jpg
isPartOf:
name:Nature Immunology
issn:
1529-2916
1529-2908
volumeNumber:8
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Eva V Acosta-Rodriguez
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Giorgio Napolitani
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
type:Person
name:Antonio Lanzavecchia
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
type:Person
name:Federica Sallusto
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature Immunology
issn:
1529-2916
1529-2908
volumeNumber:8
Organization:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Eva V Acosta-Rodriguez
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
email:[email protected]
name:Giorgio Napolitani
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
name:Antonio Lanzavecchia
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
name:Federica Sallusto
affiliation:
name:Institute for Research in Biomedicine
address:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
name:Institute for Research in Biomedicine, Bellinzona, Switzerland
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {🔗}(108)
- How much does https://link.springer.com/article/10.1038/ni1496?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle bring in each month?
- How much does https://doi.org/10.1038%2Fni1261 make?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=A%20distinct%20lineage%20of%20CD4%20T%20cells%20regulates%20tissue%20inflammation%20by%20producing%20interleukin%2017&journal=Nat.%20Immunol.&doi=10.1038%2Fni1261&volume=6&pages=1133-1141&publication_year=2005&author=Park%2CH?
- Learn how profitable https://doi.org/10.1038%2Fni1254 is on a monthly basis
- See how much http://scholar.google.com/scholar_lookup?&title=Interleukin%2017-producing%20CD4%2B%20effector%20T%20cells%20develop%20via%20a%20lineage%20distinct%20from%20the%20T%20helper%20type%201%20and%202%20lineages&journal=Nat.%20Immunol.&doi=10.1038%2Fni1254&volume=6&pages=1123-1132&publication_year=2005&author=Harrington%2CLE makes per month
- What is the monthly revenue of https://doi.org/10.1146%2Fannurev.immunol.25.022106.141557?
- How much profit does http://scholar.google.com/scholar_lookup?&title=IL-17%20family%20cytokines%20and%20the%20expanding%20diversity%20of%20effector%20T%20cell%20lineages&journal=Annu.%20Rev.%20Immunol.&doi=10.1146%2Fannurev.immunol.25.022106.141557&volume=25&pages=821-852&publication_year=2007&author=Weaver%2CCT&author=Hatton%2CRD&author=Mangan%2CPR&author=Harrington%2CLE generate?
- Earnings of https://doi.org/10.1084%2Fjem.20030896
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=Divergent%20pro-%20and%20antiinflammatory%20roles%20for%20IL-23%20and%20IL-12%20in%20joint%20autoimmune%20inflammation&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.20030896&volume=198&pages=1951-1957&publication_year=2003&author=Murphy%2CCA?
- What's the monthly income of https://doi.org/10.1172%2FJCI21404?
- How much does http://scholar.google.com/scholar_lookup?&title=IL-23%20is%20essential%20for%20T%20cell-mediated%20colitis%20and%20promotes%20inflammation%20via%20IL-17%20and%20IL-6&journal=J.%20Clin.%20Invest.&doi=10.1172%2FJCI21404&volume=116&pages=1310-1316&publication_year=2006&author=Yen%2CD bring in each month?
- What's the income generated by https://doi.org/10.1038%2Fnature05505 each month?
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Interleukin-22%2C%20a%20TH17%20cytokine%2C%20mediates%20IL-23-induced%20dermal%20inflammation%20and%20acanthosis&journal=Nature&doi=10.1038%2Fnature05505&volume=445&pages=648-651&publication_year=2007&author=Zheng%2CY?
- Profit of https://doi.org/10.1084%2Fjem.194.4.519
- Income figures for http://scholar.google.com/scholar_lookup?&title=Requirement%20of%20interleukin%2017%20receptor%20signaling%20for%20lung%20CXC%20chemokine%20and%20granulocyte%20colony-stimulating%20factor%20expression%2C%20neutrophil%20recruitment%2C%20and%20host%20defense&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.194.4.519&volume=194&pages=519-527&publication_year=2001&author=Ye%2CP
- What is the earnings of https://doi.org/10.1097%2F01.MIB.0000218764.06959.91?
- http://scholar.google.com/scholar_lookup?&title=Critical%20role%20of%20IL-17%20receptor%20signaling%20in%20acute%20TNBS-induced%20colitis&journal=Inflamm.%20Bowel%20Dis.&doi=10.1097%2F01.MIB.0000218764.06959.91&volume=12&pages=382-388&publication_year=2006&author=Zhang%2CZ&author=Zheng%2CM&author=Bindas%2CJ&author=Schwarzenberger%2CP&author=Kolls%2CJK income
- How much profit is https://doi.org/10.1002%2F1529-0131%28199905%2942%3A5%3C963%3A%3AAID-ANR15%3E3.0.CO%3B2-E making per month?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Human%20interleukin-17%3A%20A%20T%20cell-derived%20proinflammatory%20cytokine%20produced%20by%20the%20rheumatoid%20synovium&journal=Arthritis%20Rheum.&doi=10.1002%2F1529-0131%28199905%2942%3A5%3C963%3A%3AAID-ANR15%3E3.0.CO%3B2-E&volume=42&pages=963-970&publication_year=1999&author=Chabaud%2CM
- Find out how much https://doi.org/10.1038%2Fnm0502-500 earns monthly
- See how much http://scholar.google.com/scholar_lookup?&title=Gene-microarray%20analysis%20of%20multiple%20sclerosis%20lesions%20yields%20new%20targets%20validated%20in%20autoimmune%20encephalomyelitis&journal=Nat.%20Med.&doi=10.1038%2Fnm0502-500&volume=8&pages=500-508&publication_year=2002&author=Lock%2CC makes per month
- Learn about the earnings of https://doi.org/10.1136%2Fgut.52.1.65
- What's the income of http://scholar.google.com/scholar_lookup?&title=Increased%20expression%20of%20interleukin%2017%20in%20inflammatory%20bowel%20disease&journal=Gut&doi=10.1136%2Fgut.52.1.65&volume=52&pages=65-70&publication_year=2003&author=Fujino%2CS?
- How much money does https://doi.org/10.1074%2Fjbc.M207577200 make?
- How much does http://scholar.google.com/scholar_lookup?&title=Interleukin-23%20promotes%20a%20distinct%20CD4%20T%20cell%20activation%20state%20characterized%20by%20the%20production%20of%20interleukin-17&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M207577200&volume=278&pages=1910-1914&publication_year=2003&author=Aggarwal%2CS&author=Ghilardi%2CN&author=Xie%2CMH&author=de%20Sauvage%2CFJ&author=Gurney%2CAL net monthly?
- How much does https://doi.org/10.1038%2Fni1391 net monthly?
- What's the income of http://scholar.google.com/scholar_lookup?&title=Signals%20mediated%20by%20transforming%20growth%20factor-%CE%B2%20initiate%20autoimmune%20encephalomyelitis%2C%20but%20chronic%20inflammation%20is%20needed%20to%20sustain%20disease&journal=Nat.%20Immunol.&doi=10.1038%2Fni1391&volume=7&pages=1151-1156&publication_year=2006&author=Veldhoen%2CM&author=Hocking%2CRJ&author=Flavell%2CRA&author=Stockinger%2CB?
- What is the earnings of https://doi.org/10.1016%2Fj.immuni.2006.01.001?
- How much does http://scholar.google.com/scholar_lookup?&title=TGF%CE%B2%20in%20the%20context%20of%20an%20inflammatory%20cytokine%20milieu%20supports%20de%20novo%20differentiation%20of%20IL-17-producing%20T%20cells&journal=Immunity&doi=10.1016%2Fj.immuni.2006.01.001&volume=24&pages=179-189&publication_year=2006&author=Veldhoen%2CM&author=Hocking%2CRJ&author=Atkins%2CCJ&author=Locksley%2CRM&author=Stockinger%2CB gross monthly?
- https://doi.org/10.1038%2Fnature04754's financial summary
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Transforming%20growth%20factor-%CE%B2%20induces%20development%20of%20the%20TH17%20lineage&journal=Nature&doi=10.1038%2Fnature04754&volume=441&pages=231-234&publication_year=2006&author=Mangan%2CPR have monthly?
- How much profit is https://doi.org/10.1038%2Fnature04753 making per month?
- How much does http://scholar.google.com/scholar_lookup?&title=Reciprocal%20developmental%20pathways%20for%20the%20generation%20of%20pathogenic%20effector%20TH17%20and%20regulatory%20T%20cells&journal=Nature&doi=10.1038%2Fnature04753&volume=441&pages=235-238&publication_year=2006&author=Bettelli%2CE net monthly?
- What's https://doi.org/10.4049%2Fjimmunol.176.9.5652's gross income?
- How profitable is http://scholar.google.com/scholar_lookup?&title=STAT3%20and%20NF-%CE%BAB%20signal%20pathway%20is%20required%20for%20IL-23-mediated%20IL-17%20production%20in%20spontaneous%20arthritis%20animal%20model%20IL-1%20receptor%20antagonist-deficient%20mice&journal=J.%20Immunol.&doi=10.4049%2Fjimmunol.176.9.5652&volume=176&pages=5652-5661&publication_year=2006&author=Cho%2CML?
- https://doi.org/10.1002%2Feji.200535239's revenue stream
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Divergent%20effects%20of%20IL-12%20and%20IL-23%20on%20the%20production%20of%20IL-17%20by%20human%20T%20cells&journal=Eur.%20J.%20Immunol.&doi=10.1002%2Feji.200535239&volume=36&pages=661-670&publication_year=2006&author=Hoeve%2CMA?
- How much revenue does https://doi.org/10.1038%2Fni1375 produce monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Interleukin%2027%20limits%20autoimmune%20encephalomyelitis%20by%20suppressing%20the%20development%20of%20interleukin%2017-producing%20T%20cells&journal=Nat.%20Immunol.&doi=10.1038%2Fni1375&volume=7&pages=929-936&publication_year=2006&author=Batten%2CM bring in each month?
- How much profit is https://doi.org/10.1016%2Fj.immuni.2007.02.009 making per month?
- How much profit is http://scholar.google.com/scholar_lookup?&title=Interleukin-2%20signaling%20via%20STAT5%20constrains%20T%20helper%2017%20cell%20generation&journal=Immunity&doi=10.1016%2Fj.immuni.2007.02.009&volume=26&pages=371-381&publication_year=2007&author=Laurence%2CA making per month?
- What's the monthly income of https://doi.org/10.1016%2Fj.cell.2006.07.035?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20orphan%20nuclear%20receptor%20ROR%CE%B3t%20directs%20the%20differentiation%20program%20of%20proinflammatory%20IL-17%2B%20T%20helper%20cells&journal=Cell&doi=10.1016%2Fj.cell.2006.07.035&volume=126&pages=1121-1133&publication_year=2006&author=Ivanov%2CII bring in?
- What's the financial intake of https://doi.org/10.1074%2Fjbc.C600321200?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=STAT3%20regulates%20cytokine-mediated%20generation%20of%20inflammatory%20helper%20T%20cells&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.C600321200&volume=282&pages=9358-9363&publication_year=2007&author=Yang%2CXO
- https://doi.org/10.1038%2Fni1467's revenue stream
- See how much http://scholar.google.com/scholar_lookup?&title=Surface%20phenotype%20and%20antigenic%20specificity%20of%20human%20interleukin%2017%E2%80%93producing%20T%20helper%20memory%20cells&journal=Nat.%20Immunol.&doi=10.1038%2Fni1467&volume=8&pages=639-646&publication_year=2007&author=Acosta-Rodriguez%2CEV makes per month
- Profit of https://doi.org/10.1182%2Fblood-2006-04-015016
- How much does http://scholar.google.com/scholar_lookup?&title=T-bet%20is%20a%20critical%20determinant%20in%20the%20instability%20of%20the%20IL-17-secreting%20T-helper%20phenotype&journal=Blood&doi=10.1182%2Fblood-2006-04-015016&volume=108&pages=1595-1601&publication_year=2006&author=Mathur%2CAN gross monthly?
- How much does https://doi.org/10.1016%2Fj.coi.2003.11.007 pull in?
- Profit of http://scholar.google.com/scholar_lookup?&title=Activation%20of%20dendritic%20cells%3A%20translating%20innate%20into%20adaptive%20immunity&journal=Curr.%20Opin.%20Immunol.&doi=10.1016%2Fj.coi.2003.11.007&volume=16&pages=21-25&publication_year=2004&author=Reis%20e%20Sousa%2CC
- Profit of https://doi.org/10.1021%2Fbi00179a020
- Revenue of http://scholar.google.com/scholar_lookup?&title=Inactivation%20of%20interleukin-1%CE%B2%20converting%20enzyme%20by%20peptide%20%28acyloxy%29methyl%20ketones&journal=Biochemistry&doi=10.1021%2Fbi00179a020&volume=33&pages=3934-3940&publication_year=1994&author=Thornberry%2CNA
- How much revenue does https://doi.org/10.1038%2F84264 generate?
- What's the income of http://scholar.google.com/scholar_lookup?&title=IL-18-stimulated%20GADD45%CE%B2%20required%20in%20cytokine-induced%2C%20but%20not%20TCR-induced%2C%20IFN-%CE%B3%20production&journal=Nat.%20Immunol.&doi=10.1038%2F84264&volume=2&pages=157-164&publication_year=2001&author=Yang%2CJ&author=Zhu%2CH&author=Murphy%2CTL&author=Ouyang%2CW&author=Murphy%2CKM?
- How much money does https://doi.org/10.1073%2Fpnas.1035999100 generate?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=IL-17%20production%20from%20activated%20T%20cells%20is%20required%20for%20the%20spontaneous%20development%20of%20destructive%20arthritis%20in%20mice%20deficient%20in%20IL-1%20receptor%20antagonist&journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.1035999100&volume=100&pages=5986-5990&publication_year=2003&author=Nakae%2CS
- Financial intake of https://doi.org/10.1084%2Fjem.20060285
- How profitable is http://scholar.google.com/scholar_lookup?&title=A%20crucial%20role%20for%20interleukin%20%28IL%29-1%20in%20the%20induction%20of%20IL-17-producing%20T%20cells%20that%20mediate%20autoimmune%20encephalomyelitis&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.20060285&volume=203&pages=1685-1691&publication_year=2006&author=Sutton%2CC&author=Brereton%2CC&author=Keogh%2CB&author=Mills%2CKH&author=Lavelle%2CEC?
- What are the total earnings of https://doi.org/10.4049%2Fjimmunol.177.11.7980?
- How much does http://scholar.google.com/scholar_lookup?&title=TLR4%20mediates%20vaccine-induced%20protective%20cellular%20immunity%20to%20Bordetella%20pertussis%3A%20role%20of%20IL-17-producing%20T%20cells&journal=J.%20Immunol.&doi=10.4049%2Fjimmunol.177.11.7980&volume=177&pages=7980-7989&publication_year=2006&author=Higgins%2CSC&author=Jarnicki%2CAG&author=Lavelle%2CEC&author=Mills%2CKH rake in every month?
- https://doi.org/10.1038%2Fni1460 income
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Syk-%20and%20CARD9-dependent%20coupling%20of%20innate%20immunity%20to%20the%20induction%20of%20T%20helper%20cells%20that%20produce%20interleukin%2017&journal=Nat.%20Immunol.&doi=10.1038%2Fni1460&volume=8&pages=630-638&publication_year=2007&author=Leibundgut-Landmann%2CS?
- Income figures for https://doi.org/10.1038%2Fnm1246
- How much does http://scholar.google.com/scholar_lookup?&title=TLR%20activation%20triggers%20the%20rapid%20differentiation%20of%20monocytes%20into%20macrophages%20and%20dendritic%20cells&journal=Nat.%20Med.&doi=10.1038%2Fnm1246&volume=11&pages=653-660&publication_year=2005&author=Krutzik%2CSR gross monthly?
- What is the monthly revenue of https://doi.org/10.1016%2FS1074-7613%2800%2980149-1?
- How much does http://scholar.google.com/scholar_lookup?&title=Differentiation%20of%20phagocytic%20monocytes%20into%20lymph%20node%20dendritic%20cells%20in%20vivo&journal=Immunity&doi=10.1016%2FS1074-7613%2800%2980149-1&volume=11&pages=753-761&publication_year=1999&author=Randolph%2CGJ&author=Inaba%2CK&author=Robbiani%2CDF&author=Steinman%2CRM&author=Muller%2CWA make?
- What's the financial intake of https://doi.org/10.1038%2Fni1307?
- Earnings of http://scholar.google.com/scholar_lookup?&title=Langerhans%20cells%20arise%20from%20monocytes%20in%20vivo&journal=Nat.%20Immunol.&doi=10.1038%2Fni1307&volume=7&pages=265-273&publication_year=2006&author=Ginhoux%2CF
- https://doi.org/10.1084%2Fjem.194.9.1361's revenue stream
- How much income is http://scholar.google.com/scholar_lookup?&title=Inflammatory%20chemokine%20transport%20and%20presentation%20in%20HEV%3A%20a%20remote%20control%20mechanism%20for%20monocyte%20recruitment%20to%20lymph%20nodes%20in%20inflamed%20tissues&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.194.9.1361&volume=194&pages=1361-1373&publication_year=2001&author=Palframan%2CRT earning monthly?
- What are the total earnings of https://doi.org/10.1084%2Fjem.194.9.1375?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=Tumor%20necrosis%20factor-dependent%20segmental%20control%20of%20MIG%20expression%20by%20high%20endothelial%20venules%20in%20inflamed%20lymph%20nodes%20regulates%20monocyte%20recruitment&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.194.9.1375&volume=194&pages=1375-1384&publication_year=2001&author=Janatpour%2CMJ&author=Hudak%2CS&author=Sathe%2CM&author=Sedgwick%2CJD&author=McEvoy%2CLM?
- Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9647250
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Enhancing%20effect%20of%20IL-17%20on%20IL-1-induced%20IL-6%20and%20leukemia%20inhibitory%20factor%20production%20by%20rheumatoid%20arthritis%20synoviocytes%20and%20its%20regulation%20by%20Th2%20cytokines&journal=J.%20Immunol.&volume=161&pages=409-414&publication_year=1998&author=Chabaud%2CM&author=Fossiez%2CF&author=Taupin%2CJL&author=Miossec%2CP?
- How much does https://doi.org/10.1002%2Fart.21342 generate monthly?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Interleukin-17%20receptor%20deficiency%20results%20in%20impaired%20synovial%20expression%20of%20interleukin-1%20and%20matrix%20metalloproteinases%203%2C%209%2C%20and%2013%20and%20prevents%20cartilage%20destruction%20during%20chronic%20reactivated%20streptococcal%20cell%20wall-induced%20arthritis&journal=Arthritis%20Rheum.&doi=10.1002%2Fart.21342&volume=52&pages=3239-3247&publication_year=2005&author=Koenders%2CMI have monthly?
- What's the revenue for https://doi.org/10.1038%2Fncprheum0020?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Cytokine%20networks%E2%80%93towards%20new%20therapies%20for%20rheumatoid%20arthritis&journal=Nat.%20Clin.%20Pract.%20Rheumatol.&doi=10.1038%2Fncprheum0020&volume=1&pages=31-39&publication_year=2005&author=McInnes%2CIB&author=Liew%2CFY
- How much profit does https://doi.org/10.1016%2Fj.cell.2004.05.004 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=Inflammatory%20caspases%3A%20linking%20an%20intracellular%20innate%20immune%20system%20to%20autoinflammatory%20diseases&journal=Cell&doi=10.1016%2Fj.cell.2004.05.004&volume=117&pages=561-574&publication_year=2004&author=Martinon%2CF&author=Tschopp%2CJ make?
- How much does https://doi.org/10.1084%2Fjem.179.4.1109 pull in monthly?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Efficient%20presentation%20of%20soluble%20antigen%20by%20cultured%20human%20dendritic%20cells%20is%20maintained%20by%20granulocyte%2Fmacrophage%20colony-stimulating%20factor%20plus%20interleukin%204%20and%20downregulated%20by%20tumor%20necrosis%20factor%20alpha&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.179.4.1109&volume=179&pages=1109-1118&publication_year=1994&author=Sallusto%2CF&author=Lanzavecchia%2CA?
- https://doi.org/10.1084%2Fjem.187.6.961's revenue stream
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Transforming%20growth%20factor%20%CE%B21%2C%20in%20the%20presence%20of%20granulocyte%2Fmacrophage%20colony-stimulating%20factor%20and%20interleukin%204%2C%20induces%20differentiation%20of%20human%20peripheral%20blood%20monocytes%20into%20dendritic%20Langerhans%20cells&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.187.6.961&volume=187&pages=961-966&publication_year=1998&author=Geissmann%2CF?
- How much income is https://doi.org/10.1084%2Fjem.191.10.1777 earning monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Type%20I%20interferon%20as%20a%20powerful%20adjuvant%20for%20monocyte-derived%20dendritic%20cell%20development%20and%20activity%20in%20vitro%20and%20in%20Hu-PBL-SCID%20mice&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.191.10.1777&volume=191&pages=1777-1788&publication_year=2000&author=Santini%2CSM pull in monthly?
- How much does https://citation-needed.springer.com/v2/references/10.1038/ni1496?format=refman&flavour=references pull in monthly?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Eva%20V%20Acosta-Rodriguez pull in monthly?
- What's the financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Eva%20V%20Acosta-Rodriguez%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Giorgio%20Napolitani produce monthly?
- How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Giorgio%20Napolitani%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Antonio%20Lanzavecchia make?
- What's the revenue for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Antonio%20Lanzavecchia%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Federica%20Sallusto gross monthly?
- How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Federica%20Sallusto%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
- How much does https://static-content.springer.com/esm/art%3A10.1038%2Fni1496/MediaObjects/41590_2007_BFni1496_MOESM24_ESM.pdf pull in?
- Check the income stats for https://s100.copyright.com/AppDispatchServlet?title=Interleukins%201%CE%B2%20and%206%20but%20not%20transforming%20growth%20factor-%CE%B2%20are%20essential%20for%20the%20differentiation%20of%20interleukin%2017%E2%80%93producing%20human%20T%20helper%20cells&author=Eva%20V%20Acosta-Rodriguez%20et%20al&contentID=10.1038%2Fni1496©right=Springer%20Nature%20America%2C%20Inc.&publication=1529-2908&publicationDate=2007-08-05&publisherName=SpringerNature&orderBeanReset=true
- Find out how much https://citation-needed.springer.com/v2/references/10.1038/ni1496?format=refman&flavour=citation earns monthly
- What's the income generated by https://doi.org/10.1007/s10875-024-01662-4 each month?
- Profit of https://doi.org/10.1038/s41467-023-39484-4
- How much does https://doi.org/10.1007/s12026-023-09361-9 make?
- Learn about the earnings of https://doi.org/10.1038/s41590-022-01386-w
- How much money does https://doi.org/10.1007/s13206-022-00068-x generate?
- https://www.protocols.io/'s revenue stream
- https://www.natureindex.com/ income
- What's the financial intake of http://www.naturechina.com?
- Discover the revenue of https://www.natureasia.com/ja-jp
Analytics and Tracking {📊}
- Google Tag Manager
Libraries {📚}
- Prism.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {📦}
- Crossref