NATURE . COM {}

Matching Content Categories {📚}

• Science
• Telecommunications
• Health & Fitness

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,194,993 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$531,700 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $354,480 to $974,820.

Keywords {🔍}

drug, percs, pubmed, cells, fig, resistance, cancer, article, erlotinib, cell, perc, supplementary, mechanisms, google, scholar, media, cas, response, drugs, persister, central, state, data, genetic, egfr, nature, growth, sensitivity, line, lung, met, drugresistance, drugtolerant, plates, performed, curves, methods, colonies, figs, diverse, treatment, persisters, erlotinibfree, mutations, screen, mutation, inhibitors, analysis, single, multiple,

Topics {✒️}

nature portfolio privacy policy middle grey lines advertising nature 462 nature individual resistance solutions drug-resistance solutions accession number srp068321 libraries 0/ reprints persister-derived erlotinib-resistant colonies small-cell lung cancer biomek liquid-handling robot synonymous single-nucleotide variant accurate long-read alignment burrows-wheeler alignment tool large-scale drug screen17 reversing melanoma cross-resistance drug-resistant cancer populations resistance-conferring genetic mutations somatic single-nucleotide variants large-scale drug screening drug-tolerant persister state8 pdf 1827 kb sequence read archive small-scale ‘bypass’ experiment transient sirna-mediated knockdown interrogate drug-resistance mechanisms diverse drug-resistance mechanisms nci oncology set eliminating fast-growing populations drug-tolerant persister state egf receptor/akt pathway heterogeneous drug-resistance mechanisms 150–200-bp insert library genetic information long-term drug holiday diverse drug library drug-category-response score perc drug-resistance mechanisms multiple cell lines smoothed drug-response curves cancer cell populations converting cancer therapies single genetic/epigenetic state tyrosine kinase inhibitors epidermal growth factor eliminating fast-growing cells relative drug-response score

Questions {❓}

• Second-generation irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs): a better mousetrap?
• Would different initial cells, passing through the persister bottleneck, give rise to the same resistance landscape?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells
         description:Cancer therapy has traditionally focused on eliminating fast-growing populations of cells. Yet, an increasing body of evidence suggests that small subpopulations of cancer cells can evade strong selective drug pressure by entering a ‘persister’ state of negligible growth. This drug-tolerant state has been hypothesized to be part of an initial strategy towards eventual acquisition of bona fide drug-resistance mechanisms. However, the diversity of drug-resistance mechanisms that can expand from a persister bottleneck is unknown. Here we compare persister-derived, erlotinib-resistant colonies that arose from a single, EGFR-addicted lung cancer cell. We find, using a combination of large-scale drug screening and whole-exome sequencing, that our erlotinib-resistant colonies acquired diverse resistance mechanisms, including the most commonly observed clinical resistance mechanisms. Thus, the drug-tolerant persister state does not limit—and may even provide a latent reservoir of cells for—the emergence of heterogeneous drug-resistance mechanisms. Cancer cells that survive initial drug treatment can persist in the presence of drugs. Here, the authors generate persister cells that are resistant to the EGFR tyrosine kinase inhibitor erlotinib and show by single cell analysis that multiple mechanism give rise to the drug-resistant persister state.
         datePublished:2016-02-19T00:00:00Z
         dateModified:2016-02-19T00:00:00Z
         pageStart:1
         pageEnd:8
         license:http://creativecommons.org/licenses/by/4.0/
         sameAs:https://doi.org/10.1038/ncomms10690
         keywords:
            Cancer genetics
            Cancer therapeutic resistance
            Science
            Humanities and Social Sciences
            multidisciplinary
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_Article_BFncomms10690_Figa_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_Article_BFncomms10690_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_Article_BFncomms10690_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_Article_BFncomms10690_Fig3_HTML.jpg
         isPartOf:
            name:Nature Communications
            issn:
               2041-1723
            volumeNumber:7
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Michael Ramirez
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
                     name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
                     address:
                        name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Satwik Rajaram
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
                     name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
                     address:
                        name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Robert J. Steininger
               affiliation:
                     name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
                     address:
                        name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Daria Osipchuk
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Maike A. Roth
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Leanna S. Morinishi
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Louise Evans
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Weiyue Ji
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Chien-Hsiang Hsu
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Kevin Thurley
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Shuguang Wei
               affiliation:
                     name:University of Texas Southwestern Medical Center
                     address:
                        name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Anwu Zhou
               affiliation:
                     name:University of Texas Southwestern Medical Center
                     address:
                        name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Prasad R. Koduru
               affiliation:
                     name:University of Texas Southwestern Medical Center
                     address:
                        name:Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Bruce A. Posner
               affiliation:
                     name:University of Texas Southwestern Medical Center
                     address:
                        name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Lani F. Wu
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
                     name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
                     address:
                        name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Steven J. Altschuler
               affiliation:
                     name:University of California, San Francisco
                     address:
                        name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                        type:PostalAddress
                     type:Organization
                     name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
                     address:
                        name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:1
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells
      description:Cancer therapy has traditionally focused on eliminating fast-growing populations of cells. Yet, an increasing body of evidence suggests that small subpopulations of cancer cells can evade strong selective drug pressure by entering a ‘persister’ state of negligible growth. This drug-tolerant state has been hypothesized to be part of an initial strategy towards eventual acquisition of bona fide drug-resistance mechanisms. However, the diversity of drug-resistance mechanisms that can expand from a persister bottleneck is unknown. Here we compare persister-derived, erlotinib-resistant colonies that arose from a single, EGFR-addicted lung cancer cell. We find, using a combination of large-scale drug screening and whole-exome sequencing, that our erlotinib-resistant colonies acquired diverse resistance mechanisms, including the most commonly observed clinical resistance mechanisms. Thus, the drug-tolerant persister state does not limit—and may even provide a latent reservoir of cells for—the emergence of heterogeneous drug-resistance mechanisms. Cancer cells that survive initial drug treatment can persist in the presence of drugs. Here, the authors generate persister cells that are resistant to the EGFR tyrosine kinase inhibitor erlotinib and show by single cell analysis that multiple mechanism give rise to the drug-resistant persister state.
      datePublished:2016-02-19T00:00:00Z
      dateModified:2016-02-19T00:00:00Z
      pageStart:1
      pageEnd:8
      license:http://creativecommons.org/licenses/by/4.0/
      sameAs:https://doi.org/10.1038/ncomms10690
      keywords:
         Cancer genetics
         Cancer therapeutic resistance
         Science
         Humanities and Social Sciences
         multidisciplinary
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_Article_BFncomms10690_Figa_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_Article_BFncomms10690_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_Article_BFncomms10690_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_Article_BFncomms10690_Fig3_HTML.jpg
      isPartOf:
         name:Nature Communications
         issn:
            2041-1723
         volumeNumber:7
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Michael Ramirez
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
                  name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
                  address:
                     name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Satwik Rajaram
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
                  name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
                  address:
                     name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Robert J. Steininger
            affiliation:
                  name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
                  address:
                     name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Daria Osipchuk
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Maike A. Roth
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Leanna S. Morinishi
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Louise Evans
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Weiyue Ji
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Chien-Hsiang Hsu
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Kevin Thurley
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Shuguang Wei
            affiliation:
                  name:University of Texas Southwestern Medical Center
                  address:
                     name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Anwu Zhou
            affiliation:
                  name:University of Texas Southwestern Medical Center
                  address:
                     name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Prasad R. Koduru
            affiliation:
                  name:University of Texas Southwestern Medical Center
                  address:
                     name:Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bruce A. Posner
            affiliation:
                  name:University of Texas Southwestern Medical Center
                  address:
                     name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Lani F. Wu
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
                  name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
                  address:
                     name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Steven J. Altschuler
            affiliation:
                  name:University of California, San Francisco
                  address:
                     name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
                     type:PostalAddress
                  type:Organization
                  name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
                  address:
                     name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:1
["Periodical","PublicationVolume"]:
      name:Nature Communications
      issn:
         2041-1723
      volumeNumber:7
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
      address:
         name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
      address:
         name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
      address:
         name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:University of Texas Southwestern Medical Center
      address:
         name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:University of Texas Southwestern Medical Center
      address:
         name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:University of Texas Southwestern Medical Center
      address:
         name:Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:University of Texas Southwestern Medical Center
      address:
         name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
      address:
         name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
      name:University of California, San Francisco
      address:
         name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
         type:PostalAddress
      name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
      address:
         name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Michael Ramirez
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
            name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
            address:
               name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Satwik Rajaram
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
            name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
            address:
               name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Robert J. Steininger
      affiliation:
            name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
            address:
               name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Daria Osipchuk
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
      name:Maike A. Roth
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
      name:Leanna S. Morinishi
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
      name:Louise Evans
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
      name:Weiyue Ji
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
      name:Chien-Hsiang Hsu
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
      name:Kevin Thurley
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
      name:Shuguang Wei
      affiliation:
            name:University of Texas Southwestern Medical Center
            address:
               name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Anwu Zhou
      affiliation:
            name:University of Texas Southwestern Medical Center
            address:
               name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Prasad R. Koduru
      affiliation:
            name:University of Texas Southwestern Medical Center
            address:
               name:Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Bruce A. Posner
      affiliation:
            name:University of Texas Southwestern Medical Center
            address:
               name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      name:Lani F. Wu
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
            name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
            address:
               name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Steven J. Altschuler
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
            name:Green Center for Systems Biology, University of Texas Southwestern Medical Center
            address:
               name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
      name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
      name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
      name:Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
      name:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA
      name:Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
      name:Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, USA

Social Networks {👍}(2)

• https://www.facebook.com/NatureCommunications
• https://twitter.com/NatureComms

External Links {🔗}(200)

• What is the earnings of http://www.ncbi.nlm.nih.gov/sra?term=SRP068321?
• What's the financial intake of https://doi.org/10.1016%2Fj.cell.2012.02.015?
• How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22424221?
• Earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465702
• Financial intake of http://scholar.google.com/scholar_lookup?&title=Converting%20cancer%20therapies%20into%20cures%3A%20lessons%20from%20infectious%20diseases&journal=Cell&doi=10.1016%2Fj.cell.2012.02.015&volume=148&pages=1089-1098&publication_year=2012&author=Glickman%2CMS&author=Sawyers%2CCL
• See how much https://doi.org/10.1056%2FNEJMoa1113205 makes per month
• Discover the revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22397650
• Find out how much http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878653 earns monthly
• How much does http://scholar.google.com/scholar_lookup?&title=Intratumor%20heterogeneity%20and%20branched%20evolution%20revealed%20by%20multiregion%20sequencing&journal=N.%20Engl.%20J.%20Med.&doi=10.1056%2FNEJMoa1113205&volume=366&pages=883-892&publication_year=2012&author=Gerlinger%2CM pull in?
• How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19931353 generate?
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Tumor%20heterogeneity%3A%20causes%20and%20consequences&journal=Biochim.%20Biophys.%20Acta&volume=1805&pages=105-117&publication_year=2010&author=Marusyk%2CA&author=Polyak%2CK?
• What are the total earnings of https://doi.org/10.1073%2Fpnas.0710370104?
• How much revenue does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2007PNAS..10420932B generate?
• Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18093943
• How much cash flow does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409244 have monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=MET%20amplification%20occurs%20with%20or%20without%20T790M%20mutations%20in%20EGFR%20mutant%20lung%20tumors%20with%20acquired%20resistance%20to%20gefitinib%20or%20erlotinib&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0710370104&volume=104&pages=20932-20937&publication_year=2007&author=Bean%2CJ gross monthly?
• What's the monthly money flow for https://doi.org/10.1038%2Fnm.3841?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25849130 net monthly?
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Studying%20clonal%20dynamics%20in%20response%20to%20cancer%20therapy%20using%20high-complexity%20barcoding&journal=Nat.%20Med.&doi=10.1038%2Fnm.3841&volume=21&pages=440-448&publication_year=2015&author=Bhang%2CHE?
• How much cash flow does https://doi.org/10.1016%2Fj.ccr.2009.11.022 have monthly?
• What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20129249's gross income?
• How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980857 pull in monthly?
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Preexistence%20and%20clonal%20selection%20of%20MET%20amplification%20in%20EGFR%20mutant%20NSCLC&journal=Cancer%20Cell&doi=10.1016%2Fj.ccr.2009.11.022&volume=17&pages=77-88&publication_year=2010&author=Turke%2CAB?
• How much income does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22970367 have?
• What are the earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437267?
• How much does http://scholar.google.com/scholar_lookup?&title=Mechanisms%20of%20resistance%20to%20epidermal%20growth%20factor%20receptor%20inhibitors%20and%20novel%20therapeutic%20strategies%20to%20overcome%20resistance%20in%20NSCLC%20Patients&journal=Chemother.%20Res.%20Pract.&volume=2012&publication_year=2012&author=Lin%2CL&author=Bivona%2CTG earn?
• What's the financial intake of https://doi.org/10.1016%2Fj.cell.2010.02.027?
• How much cash flow does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20371346 have monthly?
• How much profit does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851638 generate?
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=A%20chromatin-mediated%20reversible%20drug-tolerant%20state%20in%20cancer%20cell%20subpopulations&journal=Cell&doi=10.1016%2Fj.cell.2010.02.027&volume=141&pages=69-80&publication_year=2010&author=Sharma%2CSV is on a monthly basis
• How much revenue does https://doi.org/10.1371%2Fjournal.ppat.1002121 bring in?
• http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21829345's total income per month
• See how much http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145784 makes per month
• What's http://scholar.google.com/scholar_lookup?&title=%E2%80%98Persisters%E2%80%99%3A%20survival%20at%20the%20cellular%20level&journal=PLoS%20Pathog.&doi=10.1371%2Fjournal.ppat.1002121&volume=7&publication_year=2011&author=Dawson%2CCC&author=Intapa%2CC&author=Jabra-Rizk%2CMA's gross income?
• How much does https://doi.org/10.1126%2Fscience.1099390 net monthly?
• How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2004Sci...305.1622B make?
• Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15308767
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Bacterial%20persistence%20as%20a%20phenotypic%20switch&journal=Science&doi=10.1126%2Fscience.1099390&volume=305&pages=1622-1625&publication_year=2004&author=Balaban%2CNQ&author=Merrin%2CJ&author=Chait%2CR&author=Kowalik%2CL&author=Leibler%2CS?
• How much profit does https://doi.org/10.1158%2F0008-5472.CAN-15-1113 make?
• How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26490646 make?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20casein%20kinase%201%20alpha%20prevents%20acquired%20drug%20resistance%20to%20erlotinib%20in%20EGFR-mutant%20non-small%20cell%20lung%20cancer&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-15-1113&volume=75&pages=4937-4948&publication_year=2015&author=Lantermann%2CAB bring in?
• What's the financial gain of https://doi.org/10.1080%2F15384101.2015.1090063?
• Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26566863
• What's the financial intake of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825557?
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=The%20histone%20demethylase%20KDM5A%20is%20a%20key%20factor%20for%20the%20resistance%20to%20temozolomide%20in%20glioblastoma&journal=Cell%20Cycle&doi=10.1080%2F15384101.2015.1090063&volume=14&pages=3418-3429&publication_year=2015&author=Banelli%2CB
• How much does https://doi.org/10.1016%2Fj.phrs.2015.09.022 earn?
• Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26453958
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=AKT%20inactivation%20causes%20persistent%20drug%20tolerance%20to%20EGFR%20inhibitors&journal=Pharmacol.%20Res.&doi=10.1016%2Fj.phrs.2015.09.022&volume=102&pages=132-137&publication_year=2015&author=Tetsu%2CO&author=Phuchareon%2CJ&author=Eisele%2CDW&author=Hangauer%2CMJ&author=McCormick%2CF is on a monthly basis
• How much does https://doi.org/10.1038%2Fnrclinonc.2014.104 gross monthly?
• What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24981256?
• How much does http://scholar.google.com/scholar_lookup?&title=Acquired%20resistance%20to%20TKIs%20in%20solid%20tumours%3A%20learning%20from%20lung%20cancer&journal=Nat.%20Rev.%20Clin.%20Oncol.&doi=10.1038%2Fnrclinonc.2014.104&volume=11&pages=473-481&publication_year=2014&author=Camidge%2CDR&author=Pao%2CW&author=Sequist%2CLV net monthly?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15078990 gross monthly?
• How much money does http://scholar.google.com/scholar_lookup?&title=Sensitivity%20to%20gefitinib%20%28Iressa%2C%20ZD1839%29%20in%20non-small%20cell%20lung%20cancer%20cell%20lines%20correlates%20with%20dependence%20on%20the%20epidermal%20growth%20factor%20%28EGF%29%20receptor%2Fextracellular%20signal-regulated%20kinase%201%2F2%20and%20EGF%20receptor%2FAkt%20pathway%20for%20proliferation&journal=Mol.%20Cancer%20Ther.&volume=3&pages=465-472&publication_year=2004&author=Ono%2CM generate?
• Find out how much https://doi.org/10.1126%2Fscitranslmed.3002356 earns monthly
• What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21734175?
• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500629's revenue stream
• Revenue of http://scholar.google.com/scholar_lookup?&title=Optimization%20of%20dosing%20for%20EGFR-mutant%20non-small%20cell%20lung%20cancer%20with%20evolutionary%20cancer%20modeling&journal=Sci.%20Transl.%20Med.&doi=10.1126%2Fscitranslmed.3002356&volume=3&publication_year=2011&author=Chmielecki%2CJ
• How much does https://doi.org/10.1126%2Fscience.1254721 net monthly?
• http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2014Sci...346.1480C income
• How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25394791 generate?
• How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388482 rake in every month?
• Explore the financials of http://scholar.google.com/scholar_lookup?&title=Patient-derived%20models%20of%20acquired%20resistance%20can%20identify%20effective%20drug%20combinations%20for%20cancer&journal=Science&doi=10.1126%2Fscience.1254721&volume=346&pages=1480-1486&publication_year=2014&author=Crystal%2CAS
• https://doi.org/10.1038%2Fnature08622's total income per month
• What is the earnings of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2009Natur.462.1070Z?
• What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20033049?
• How much profit does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879581 generate?
• Earnings of http://scholar.google.com/scholar_lookup?&title=Novel%20mutant-selective%20EGFR%20kinase%20inhibitors%20against%20EGFR%20T790M&journal=Nature&doi=10.1038%2Fnature08622&volume=462&pages=1070-1074&publication_year=2009&author=Zhou%2CW
• How much does https://doi.org/10.1016%2Fj.critrevonc.2011.11.010 earn?
• Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22257651
• How profitable is http://scholar.google.com/scholar_lookup?&title=Second-generation%20irreversible%20epidermal%20growth%20factor%20receptor%20%28EGFR%29%20tyrosine%20kinase%20inhibitors%20%28TKIs%29%3A%20a%20better%20mousetrap%3F%20A%20review%20of%20the%20clinical%20evidence&journal=Crit.%20Rev.%20Oncol.%20Hematol.&doi=10.1016%2Fj.critrevonc.2011.11.010&volume=83&pages=407-421&publication_year=2012&author=Ou%2CSH?
• Earnings of https://doi.org/10.1371%2Fjournal.pmed.0020017
• http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15696205's financial summary
• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC545207's total income per month
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=KRAS%20mutations%20and%20primary%20resistance%20of%20lung%20adenocarcinomas%20to%20gefitinib%20or%20erlotinib&journal=PLoS%20Med.&doi=10.1371%2Fjournal.pmed.0020017&volume=2&publication_year=2005&author=Pao%2CW?
• How much does https://doi.org/10.1056%2FNEJMoa044238 net monthly?
• See how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15728811 makes per month
• How much income is http://scholar.google.com/scholar_lookup?&title=EGFR%20mutation%20and%20resistance%20of%20non-small-cell%20lung%20cancer%20to%20gefitinib&journal=N.%20Engl.%20J.%20Med.&doi=10.1056%2FNEJMoa044238&volume=352&pages=786-792&publication_year=2005&author=Kobayashi%2CS earning monthly?
• Explore the financials of https://doi.org/10.1038%2Fsrep05193
• See how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24898935 makes per month
• How profitable is http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046135?
• How much does http://scholar.google.com/scholar_lookup?&title=Quantitative%20scoring%20of%20differential%20drug%20sensitivity%20for%20individually%20optimized%20anticancer%20therapies&journal=Sci.%20Rep.&doi=10.1038%2Fsrep05193&volume=4&publication_year=2014&author=Yadav%2CB bring in each month?
• What's https://doi.org/10.1038%2Fnchembio.1337's gross income?
• Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24013279
• How much income does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947796 have?
• Get to know http://scholar.google.com/scholar_lookup?&title=Metrics%20other%20than%20potency%20reveal%20systematic%20variation%20in%20responses%20to%20cancer%20drugs&journal=Nat.%20Chem.%20Biol.&doi=10.1038%2Fnchembio.1337&volume=9&pages=708-714&publication_year=2013&author=Fallahi-Sichani%2CM&author=Honarnejad%2CS&author=Heiser%2CLM&author=Grey%2CJW&author=Sorger%2CPK's earnings
• What's the profit of https://doi.org/10.1038%2Fnchembio.1690?
• Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25402767
• How much revenue does http://scholar.google.com/scholar_lookup?&title=GSK-3%20modulates%20cellular%20responses%20to%20a%20broad%20spectrum%20of%20kinase%20inhibitors&journal=Nat.%20Chem.%20Biol.&doi=10.1038%2Fnchembio.1690&volume=11&pages=58-63&publication_year=2015&author=Thorne%2CCA bring in?
• https://doi.org/10.1101%2Fgr.152322.112's total income per month
• What's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23733853?
• Discover the revenue of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759720
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Next-generation%20sequencing%20of%20paired%20tyrosine%20kinase%20inhibitor-sensitive%20and%20-resistant%20EGFR%20mutant%20lung%20cancer%20cell%20lines%20identifies%20spectrum%20of%20DNA%20changes%20associated%20with%20drug%20resistance&journal=Genome%20Res.&doi=10.1101%2Fgr.152322.112&volume=23&pages=1434-1445&publication_year=2013&author=Jia%2CP
• How much does https://doi.org/10.1126%2Fscience.1141478 pull in?
• How much money does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2007Sci...316.1039E make?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17463250 pull in?
• How much income is http://scholar.google.com/scholar_lookup?&title=MET%20amplification%20leads%20to%20gefitinib%20resistance%20in%20lung%20cancer%20by%20activating%20ERBB3%20signaling&journal=Science&doi=10.1126%2Fscience.1141478&volume=316&pages=1039-1043&publication_year=2007&author=Engelman%2CJA earning monthly?
• What's the financial outcome of https://doi.org/10.1158%2F2159-8290.CD-12-0103?
• How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22961667 produce monthly?
• What's the profit of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477553?
• Find out how much http://scholar.google.com/scholar_lookup?&title=Reactivation%20of%20ERK%20signaling%20causes%20resistance%20to%20EGFR%20kinase%20inhibitors&journal=Cancer%20Discov.&doi=10.1158%2F2159-8290.CD-12-0103&volume=2&pages=934-947&publication_year=2012&author=Ercan%2CD earns monthly
• What is the earnings of https://doi.org/10.1158%2F0008-5472.CAN-14-3167?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25870145 bring in each month?
• Find out how much http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605607 earns monthly
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Acquired%20resistance%20to%20the%20mutant-selective%20EGFR%20inhibitor%20AZD9291%20is%20associated%20with%20increased%20dependence%20on%20RAS%20signaling%20in%20preclinical%20models&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-14-3167&volume=75&pages=2489-2500&publication_year=2015&author=Eberlein%2CCA?
• Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11389083
• http://scholar.google.com/scholar_lookup?&title=High-throughput%20tissue%20microarray%20analysis%20of%203p25%20%28RAF1%29%20and%208p12%20%28FGFR1%29%20copy%20number%20alterations%20in%20urinary%20bladder%20cancer&journal=Cancer%20Res.&volume=61&pages=4514-4519&publication_year=2001&author=Simon%2CR's total income per month
• How much does https://doi.org/10.1371%2Fjournal.pone.0028973 generate monthly?
• How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2011PLoSO...628973A gross monthly?
• Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22194965
• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237573's total income per month
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Reversing%20melanoma%20cross-resistance%20to%20BRAF%20and%20MEK%20inhibitors%20by%20co-targeting%20the%20AKT%2FmTOR%20pathway&journal=PLoS%20ONE&doi=10.1371%2Fjournal.pone.0028973&volume=6&publication_year=2011&author=Atefi%2CM?
• How much does https://doi.org/10.1126%2Fscisignal.2004652 pull in?
• What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24065147?
• Explore the financials of http://scholar.google.com/scholar_lookup?&title=Bypass%20mechanisms%20of%20resistance%20to%20receptor%20tyrosine%20kinase%20inhibition%20in%20lung%20cancer&journal=Sci.%20Signal.&doi=10.1126%2Fscisignal.2004652&volume=6&publication_year=2013&author=Niederst%2CMJ&author=Engelman%2CJA
• How much profit does https://doi.org/10.1073%2Fpnas.0510857103 make?
• How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2006PNAS..103.1475B pull in?
• What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16432179?
• How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360603 pull in?
• How much money does http://scholar.google.com/scholar_lookup?&title=Cancer-specific%20mutations%20in%20PIK3CA%20are%20oncogenic%20in%20vivo&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0510857103&volume=103&pages=1475-1479&publication_year=2006&author=Bader%2CAG&author=Kang%2CS&author=Vogt%2CPK generate?
• What is the earnings of https://doi.org/10.1158%2F1535-7163.MCT-11-0692?
• What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22135231's gross income?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Coexistence%20of%20PIK3CA%20and%20other%20oncogene%20mutations%20in%20lung%20adenocarcinoma-rationale%20for%20comprehensive%20mutation%20profiling&journal=Mol.%20Cancer%20Ther.&doi=10.1158%2F1535-7163.MCT-11-0692&volume=11&pages=485-491&publication_year=2012&author=Chaft%2CJE
• https://doi.org/10.1128%2FMCB.01124-09 income
• What's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19995904?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=DNA%20polymerase%20POLN%20participates%20in%20cross-link%20repair%20and%20homologous%20recombination&journal=Mol.%20Cell%20Biol.&doi=10.1128%2FMCB.01124-09&volume=30&pages=1088-1096&publication_year=2010&author=Moldovan%2CGL
• What's the total monthly financial gain of https://doi.org/10.1158%2F0008-5472.CAN-10-0460?
• How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20643779 make?
• Revenue of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932856
• http://scholar.google.com/scholar_lookup?&title=Identification%20of%20optimal%20drug%20combinations%20targeting%20cellular%20networks%3A%20integrating%20phospho-proteomics%20and%20computational%20network%20analysis&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-10-0460&volume=70&pages=6704-6714&publication_year=2010&author=Iadevaia%2CS&author=Lu%2CY&author=Morales%2CFC&author=Mills%2CGB&author=Ram%2CPT income
• How much does https://doi.org/10.1371%2Fjournal.pbio.1001296 earn?
• What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22509130?
• How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317895 gross monthly?
• Find out how much http://scholar.google.com/scholar_lookup?&title=Nonheritable%20cellular%20variability%20accelerates%20the%20evolutionary%20processes%20of%20cancer&journal=PLoS%20Biol.&doi=10.1371%2Fjournal.pbio.1001296&volume=10&publication_year=2012&author=Frank%2CSA&author=Rosner%2CMR earns monthly
• Get to know https://link.springer.com/doi/10.1186/s13029-014-0027-x's earnings
• Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=25614758
• What are the total earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279979?
• Revenue of http://scholar.google.com/scholar_lookup?&title=Robust%20dose-response%20curve%20estimation%20applied%20to%20high%20content%20screening%20data%20analysis&journal=Source%20Code%20Biol.%20Med.&doi=10.1186%2Fs13029-014-0027-x&volume=9&publication_year=2014&author=Nguyen%2CTT
• How much does https://doi.org/10.1093%2Fbioinformatics%2Fbtp698 earn?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20080505 net monthly?
• Discover the revenue of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828108
• How much does http://scholar.google.com/scholar_lookup?&title=Fast%20and%20accurate%20long-read%20alignment%20with%20Burrows-Wheeler%20transform&journal=Bioinformatics&doi=10.1093%2Fbioinformatics%2Fbtp698&volume=26&pages=589-595&publication_year=2010&author=Li%2CH&author=Durbin%2CR make?
• What's the monthly income of https://doi.org/10.1038%2Fnbt.2514?
• How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23396013 generate?
• How much profit is http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833702 making per month?
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Sensitive%20detection%20of%20somatic%20point%20mutations%20in%20impure%20and%20heterogeneous%20cancer%20samples&journal=Nat.%20Biotechnol.&doi=10.1038%2Fnbt.2514&volume=31&pages=213-219&publication_year=2013&author=Cibulskis%2CK
• How much income does https://doi.org/10.1093%2Fbioinformatics%2Fbtr462 have?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21828086 pull in?
• How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179661 gross monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=Exome%20sequencing-based%20copy-number%20variation%20and%20loss%20of%20heterozygosity%20detection%3A%20ExomeCNV&journal=Bioinformatics&doi=10.1093%2Fbioinformatics%2Fbtr462&volume=27&pages=2648-2654&publication_year=2011&author=Sathirapongsasuti%2CJF gross monthly?
• How much does https://citation-needed.springer.com/v2/references/10.1038/ncomms10690?format=refman&flavour=references net monthly?
• What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Michael%20Ramirez each month?
• What's the financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Michael%20Ramirez%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Satwik%20Rajaram pull in monthly?
• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Satwik%20Rajaram%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Robert%20J.%20Steininger bring in each month?
• How much profit is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Robert%20J.%20Steininger%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en making per month?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Daria%20Osipchuk bring in each month?
• What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Daria%20Osipchuk%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the revenue for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Maike%20A.%20Roth?
• What is the monthly revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Maike%20A.%20Roth%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Leanna%20S.%20Morinishi net monthly?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Leanna%20S.%20Morinishi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Louise%20Evans's total income per month
• Find out how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Louise%20Evans%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earns monthly
• Check the income stats for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Weiyue%20Ji
• Find out how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Weiyue%20Ji%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earns monthly
• How much cash flow does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Chien-Hsiang%20Hsu have monthly?
• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Chien-Hsiang%20Hsu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kevin%20Thurley produce monthly?
• Get to know what's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kevin%20Thurley%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Shuguang%20Wei pull in monthly?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Shuguang%20Wei%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Anwu%20Zhou bring in each month?
• What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Anwu%20Zhou%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Prasad%20R.%20Koduru
• Revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Prasad%20R.%20Koduru%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Bruce%20A.%20Posner making per month?
• See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Bruce%20A.%20Posner%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
• Find out how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lani%20F.%20Wu earns monthly
• What's https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lani%20F.%20Wu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's gross income?
• Explore the financials of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Steven%20J.%20Altschuler
• Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Steven%20J.%20Altschuler%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Earnings of https://static-content.springer.com/esm/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_BFncomms10690_MOESM1080_ESM.pdf
• https://static-content.springer.com/esm/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_BFncomms10690_MOESM1081_ESM.xls's total income per month
• How much does https://static-content.springer.com/esm/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_BFncomms10690_MOESM1082_ESM.txt gross monthly?
• How much does https://static-content.springer.com/esm/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_BFncomms10690_MOESM1083_ESM.txt make?
• How much income is https://static-content.springer.com/esm/art%3A10.1038%2Fncomms10690/MediaObjects/41467_2016_BFncomms10690_MOESM1084_ESM.txt earning monthly?
• How much does http://creativecommons.org/licenses/by/4.0/ earn?
• Profit of https://s100.copyright.com/AppDispatchServlet?title=Diverse%20drug-resistance%20mechanisms%20can%20emerge%20from%20drug-tolerant%20cancer%20persister%20cells&author=Michael%20Ramirez%20et%20al&contentID=10.1038%2Fncomms10690©right=The%20Author%28s%29&publication=2041-1723&publicationDate=2016-02-19&publisherName=SpringerNature&orderBeanReset=true&oa=CC%20BY
• How much income does https://crossmark.crossref.org/dialog/?doi=10.1038/ncomms10690 have?
• What's the monthly income of https://citation-needed.springer.com/v2/references/10.1038/ncomms10690?format=refman&flavour=citation?
• What's the profit of https://doi.org/10.1038/s41588-023-01592-8?
• Learn how profitable https://doi.org/10.1186/s40164-023-00434-x is on a monthly basis
• What's https://doi.org/10.1038/s41698-023-00350-7's gross income?
• Learn about the earnings of https://doi.org/10.1038/s41598-023-34438-8
• How much money does https://doi.org/10.1038/s41418-022-01064-2 generate?
• How much money does https://www.protocols.io/ generate?
• How profitable is https://www.natureindex.com/?
• What's the income generated by http://www.naturechina.com each month?
• Learn how profitable https://www.natureasia.com/ja-jp is on a monthly basis

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref