NATURE . COM {}

Matching Content Categories {📚}

• Science
• Education
• Health & Fitness

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$63,100 per month
Estimations show Nature.com's display ad online revenue falls between $42,042 and $115,616 per month.

Keywords {🔍}

cancer, cells, article, google, scholar, cas, breast, stem, mesenchymal, nature, human, cell, access, research, tumour, metastasis, chemokine, res, data, tumor, content, stroma, bone, raw, cookies, analysis, metastatic, ccl, expression, usa, privacy, information, promote, open, pubmed, massachusetts, october, karnoub, weinberg, carcinoma, rantes, receptor, phenotype, progression, delivery, ads, marrow, aek, author, performed,

Topics {✒️}

nature portfolio permissions reprints privacy policy advertising mesenchymal/stromal stem cells social media nature rev msc-stimulated cancer cells dana-farber cancer institute nature 400 nature 449 nature elevated sdf-1/cxcl12 secretion steady-state fibroblast subtypes bone marrow cells mesenchymal stem cells research excellence supervised research biomedical research human breast cancer human tumour cells springerlink instant access targeted-gene delivery vehicles sage data analysis mesenchymal progenitor cells breast carcinoma progression author contributions author correspondence development permissions breast cancer metastasis research normal human breast tumor stroma formation advanced breast carcinoma clinical microarray data small interfering rna epithelial-mesenchymal transitions growth factor signaling bone marrow provided human mscs rat glioma model chemokine receptor ccr5 harvard medical school privacy chemokine receptor transactivation differential gene expression competing financial interests perturbed-state fibroblasts pre-malignant state

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
         description:Mesenchymal stem cells have been recently described to localize to breast carcinomas, where they integrate into the tumour-associated stroma. However, the involvement of mesenchymal stem cells (or their derivatives) in tumour pathophysiology has not been addressed. Here, we demonstrate that bone-marrow-derived human mesenchymal stem cells, when mixed with otherwise weakly metastatic human breast carcinoma cells, cause the cancer cells to increase their metastatic potency greatly when this cell mixture is introduced into a subcutaneous site and allowed to form a tumour xenograft. The breast cancer cells stimulate de novo secretion of the chemokine CCL5 (also called RANTES) from mesenchymal stem cells, which then acts in a paracrine fashion on the cancer cells to enhance their motility, invasion and metastasis. This enhanced metastatic ability is reversible and is dependent on CCL5 signalling through the chemokine receptor CCR5. Collectively, these data demonstrate that the tumour microenvironment facilitates metastatic spread by eliciting reversible changes in the phenotype of cancer cells. New work with human breast cancer cells shows that they cooperate with mesenchymal stem cells (MSCs) derived from the bone marrow to advance metastasis. The breast cancer cells prompt MSCs to produce a cytokine, CCL5, that acts on cancer cells to promote their invasion and metastasis. Significantly, the MSC-stimulated cancer cells do not acquire a stable metastatic phenotype; rather they revert to their pre-malignant state in the absence of contextual signals. This raises the possibility that metastatic programming of cancer cells may be reversed therapeutically by targeting CCL5 or its receptor. Engrafted mesenchymal stem cells (MSCs) promote breast cancer metastasis formation. Breast cancer cells induce MSCs to produce the cytokine CCL5, which then acts on breast tumour cells, enhancing their ability to migrate and extravasate blood vessel at the site of future metastases.
         datePublished:2007-10-04T00:00:00Z
         dateModified:2007-10-04T00:00:00Z
         pageStart:557
         pageEnd:563
         sameAs:https://doi.org/10.1038/nature06188
         keywords:
            Science
            Humanities and Social Sciences
            multidisciplinary
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig5_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig6_HTML.jpg
         isPartOf:
            name:Nature
            issn:
               1476-4687
               0028-0836
            volumeNumber:449
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Antoine E. Karnoub
               affiliation:
                     name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
                     address:
                        name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ajeeta B. Dash
               affiliation:
                     name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
                     address:
                        name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Annie P. Vo
               affiliation:
                     name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
                     address:
                        name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Andrew Sullivan
               affiliation:
                     name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
                     address:
                        name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mary W. Brooks
               affiliation:
                     name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
                     address:
                        name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:George W. Bell
               affiliation:
                     name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
                     address:
                        name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Andrea L. Richardson
               affiliation:
                     name:Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA
                     address:
                        name:Department of Pathology, Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Kornelia Polyak
               affiliation:
                     name:Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
                     address:
                        name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ross Tubo
               affiliation:
                     name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
                     address:
                        name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Robert A. Weinberg
               affiliation:
                     name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
                     address:
                        name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
      description:Mesenchymal stem cells have been recently described to localize to breast carcinomas, where they integrate into the tumour-associated stroma. However, the involvement of mesenchymal stem cells (or their derivatives) in tumour pathophysiology has not been addressed. Here, we demonstrate that bone-marrow-derived human mesenchymal stem cells, when mixed with otherwise weakly metastatic human breast carcinoma cells, cause the cancer cells to increase their metastatic potency greatly when this cell mixture is introduced into a subcutaneous site and allowed to form a tumour xenograft. The breast cancer cells stimulate de novo secretion of the chemokine CCL5 (also called RANTES) from mesenchymal stem cells, which then acts in a paracrine fashion on the cancer cells to enhance their motility, invasion and metastasis. This enhanced metastatic ability is reversible and is dependent on CCL5 signalling through the chemokine receptor CCR5. Collectively, these data demonstrate that the tumour microenvironment facilitates metastatic spread by eliciting reversible changes in the phenotype of cancer cells. New work with human breast cancer cells shows that they cooperate with mesenchymal stem cells (MSCs) derived from the bone marrow to advance metastasis. The breast cancer cells prompt MSCs to produce a cytokine, CCL5, that acts on cancer cells to promote their invasion and metastasis. Significantly, the MSC-stimulated cancer cells do not acquire a stable metastatic phenotype; rather they revert to their pre-malignant state in the absence of contextual signals. This raises the possibility that metastatic programming of cancer cells may be reversed therapeutically by targeting CCL5 or its receptor. Engrafted mesenchymal stem cells (MSCs) promote breast cancer metastasis formation. Breast cancer cells induce MSCs to produce the cytokine CCL5, which then acts on breast tumour cells, enhancing their ability to migrate and extravasate blood vessel at the site of future metastases.
      datePublished:2007-10-04T00:00:00Z
      dateModified:2007-10-04T00:00:00Z
      pageStart:557
      pageEnd:563
      sameAs:https://doi.org/10.1038/nature06188
      keywords:
         Science
         Humanities and Social Sciences
         multidisciplinary
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig5_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_Fig6_HTML.jpg
      isPartOf:
         name:Nature
         issn:
            1476-4687
            0028-0836
         volumeNumber:449
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Antoine E. Karnoub
            affiliation:
                  name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
                  address:
                     name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ajeeta B. Dash
            affiliation:
                  name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
                  address:
                     name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Annie P. Vo
            affiliation:
                  name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
                  address:
                     name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Andrew Sullivan
            affiliation:
                  name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
                  address:
                     name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mary W. Brooks
            affiliation:
                  name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
                  address:
                     name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:George W. Bell
            affiliation:
                  name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
                  address:
                     name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Andrea L. Richardson
            affiliation:
                  name:Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA
                  address:
                     name:Department of Pathology, Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Kornelia Polyak
            affiliation:
                  name:Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
                  address:
                     name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ross Tubo
            affiliation:
                  name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
                  address:
                     name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Robert A. Weinberg
            affiliation:
                  name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
                  address:
                     name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature
      issn:
         1476-4687
         0028-0836
      volumeNumber:449
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
      address:
         name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
         type:PostalAddress
      name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
      address:
         name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
         type:PostalAddress
      name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
      address:
         name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
         type:PostalAddress
      name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
      address:
         name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
         type:PostalAddress
      name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
      address:
         name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
         type:PostalAddress
      name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
      address:
         name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
         type:PostalAddress
      name:Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA
      address:
         name:Department of Pathology, Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA,
         type:PostalAddress
      name:Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
      address:
         name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA,
         type:PostalAddress
      name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
      address:
         name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
         type:PostalAddress
      name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
      address:
         name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Antoine E. Karnoub
      affiliation:
            name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
            address:
               name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
               type:PostalAddress
            type:Organization
      name:Ajeeta B. Dash
      affiliation:
            name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
            address:
               name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
               type:PostalAddress
            type:Organization
      name:Annie P. Vo
      affiliation:
            name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
            address:
               name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
               type:PostalAddress
            type:Organization
      name:Andrew Sullivan
      affiliation:
            name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
            address:
               name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
               type:PostalAddress
            type:Organization
      name:Mary W. Brooks
      affiliation:
            name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
            address:
               name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
               type:PostalAddress
            type:Organization
      name:George W. Bell
      affiliation:
            name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
            address:
               name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
               type:PostalAddress
            type:Organization
      name:Andrea L. Richardson
      affiliation:
            name:Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA
            address:
               name:Department of Pathology, Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA,
               type:PostalAddress
            type:Organization
      name:Kornelia Polyak
      affiliation:
            name:Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
            address:
               name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA,
               type:PostalAddress
            type:Organization
      name:Ross Tubo
      affiliation:
            name: Genzyme Corporation, Framingham, Massachusetts 01701, USA
            address:
               name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
               type:PostalAddress
            type:Organization
      name:Robert A. Weinberg
      affiliation:
            name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
            address:
               name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
      name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
      name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
      name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
      name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
      name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
      name:Department of Pathology, Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA,
      name:Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA,
      name: Genzyme Corporation, Framingham, Massachusetts 01701, USA ,
      name: Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA ,
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

• https://www.facebook.com/Nature
• https://twitter.com/nature

External Links {🔗}(111)

• What's the income of https://link.springer.com/article/10.1038/nature06188?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle?
• How much does https://doi.org/10.1038%2F35094059 make?
• What's the income generated by http://scholar.google.com/scholar_lookup?&title=Putting%20tumours%20in%20context&journal=Nature%20Rev.%20Cancer&doi=10.1038%2F35094059&volume=1&pages=46-54&publication_year=2001&author=Bissell%2CMJ&author=Radisky%2CD each month?
• Learn how profitable https://link.springer.com/doi/10.1007/978-3-540-68976-8_12 is on a monthly basis
• How much does http://scholar.google.com/scholar_lookup?&title=The%20participation%20of%20mesenchymal%20stem%20cells%20in%20tumor%20stroma%20formation%20and%20their%20application%20as%20targeted-gene%20delivery%20vehicles&journal=Handb.%20Exp.%20Pharmacol.&doi=10.1007%2F978-3-540-68976-8_12&volume=180&pages=263-283&publication_year=2007&author=Hall%2CB&author=Andreeff%2CM&author=Marini%2CF net monthly?
• Profit of https://doi.org/10.1126%2Fscience.284.5411.143
• What's http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1999Sci...284..143P's gross income?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Multilineage%20potential%20of%20adult%20human%20mesenchymal%20stem%20cells&journal=Science&doi=10.1126%2Fscience.284.5411.143&volume=284&pages=143-147&publication_year=1999&author=Pittenger%2CMF bring in?
• Monthly income for https://doi.org/10.1002%2Far.1112
• Profit of http://scholar.google.com/scholar_lookup?&title=Clonogenic%20analysis%20reveals%20reserve%20stem%20cells%20in%20postnatal%20mammals%3A%20I.%20Pluripotent%20mesenchymal%20stem%20cells&journal=Anat.%20Rec.&doi=10.1002%2Far.1112&volume=263&pages=350-360&publication_year=2001&author=Young%2CHE
• How much profit does https://doi.org/10.1002%2Far.1128 make?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Human%20reserve%20pluripotent%20mesenchymal%20stem%20cells%20are%20present%20in%20the%20connective%20tissues%20of%20skeletal%20muscle%20and%20dermis%20derived%20from%20fetal%2C%20adult%2C%20and%20geriatric%20donors&journal=Anat.%20Rec.&doi=10.1002%2Far.1128&volume=264&pages=51-62&publication_year=2001&author=Young%2CHE generate?
• How much does https://doi.org/10.1111%2Fj.1365-2141.2007.06610.x earn?
• Financial intake of http://scholar.google.com/scholar_lookup?&title=Recent%20advances%20into%20the%20understanding%20of%20mesenchymal%20stem%20cell%20trafficking&journal=Br.%20J.%20Haematol.&doi=10.1111%2Fj.1365-2141.2007.06610.x&volume=137&pages=491-502&publication_year=2007&author=Fox%2CJM&author=Chamberlain%2CG&author=Ashton%2CBA&author=Middleton%2CJ
• What's the income of https://doi.org/10.1016%2Fj.yexcr.2005.03.018?
• See how much http://scholar.google.com/scholar_lookup?&title=Non-hematopoietic%20bone%20marrow%20stem%20cells%3A%20molecular%20control%20of%20expansion%20and%20differentiation&journal=Exp.%20Cell%20Res.&doi=10.1016%2Fj.yexcr.2005.03.018&volume=306&pages=330-335&publication_year=2005&author=Gregory%2CCA&author=Prockop%2CDJ&author=Spees%2CJL makes per month
• https://doi.org/10.1016%2FS1357-4310%2800%2901756-1's revenue stream
• Monthly income for http://scholar.google.com/scholar_lookup?&title=The%20influence%20of%20the%20microenvironment%20on%20the%20malignant%20phenotype&journal=Mol.%20Med.%20Today&doi=10.1016%2FS1357-4310%2800%2901756-1&volume=6&pages=324-329&publication_year=2000&author=Park%2CCC&author=Bissell%2CMJ&author=Barcellos-Hoff%2CMH
• Profit of https://doi.org/10.1038%2Fsj.gt.3302276
• What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Antitumor%20effect%20of%20genetically%20engineered%20mesenchymal%20stem%20cells%20in%20a%20rat%20glioma%20model&journal=Gene%20Ther.&doi=10.1038%2Fsj.gt.3302276&volume=11&pages=1155-1164&publication_year=2004&author=Nakamura%2CK?
• Explore the financials of https://doi.org/10.1158%2F0008-5472.CAN-04-1874
• How much money does http://scholar.google.com/scholar_lookup?&title=Human%20bone%20marrow-derived%20mesenchymal%20stem%20cells%20in%20the%20treatment%20of%20gliomas&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-04-1874&volume=65&pages=3307-3318&publication_year=2005&author=Nakamizo%2CA generate?
• What are the total earnings of https://doi.org/10.1158%2F1078-0432.CCR-05-0876?
• How much does http://scholar.google.com/scholar_lookup?&title=Mesenchymal%20stem%20cell%20targeting%20of%20microscopic%20tumors%20and%20tumor%20stroma%20development%20monitored%20by%20noninvasive%20in%20vivo%20positron%20emission%20tomography%20imaging&journal=Clin.%20Cancer%20Res.&doi=10.1158%2F1078-0432.CCR-05-0876&volume=11&pages=7749-7756&publication_year=2005&author=Hung%2CSC make?
• How much profit is https://doi.org/10.1634%2Fstemcells.2006-0257 making per month?
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Differential%20gene%20expression%20associated%20with%20migration%20of%20mesenchymal%20stem%20cells%20to%20conditioned%20medium%20from%20tumor%20cells%20or%20bone%20marrow%20cells&journal=Stem%20Cells&doi=10.1634%2Fstemcells.2006-0257&volume=25&pages=520-528&publication_year=2007&author=Menon%2CLG
• How much does https://doi.org/10.1158%2F1535-7163.MCT-05-0334 generate monthly?
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Mesenchymal%20progenitor%20cells%20as%20cellular%20vehicles%20for%20delivery%20of%20oncolytic%20adenoviruses&journal=Mol.%20Cancer%20Ther.&doi=10.1158%2F1535-7163.MCT-05-0334&volume=5&pages=755-766&publication_year=2006&author=Komarova%2CS&author=Kawakami%2CY&author=Stoff-Khalili%2CMA&author=Curiel%2CDT&author=Pereboeva%2CL?
• What's the monthly money flow for https://doi.org/10.1084%2Fjem.20051921?
• How much does http://scholar.google.com/scholar_lookup?&title=Human%20mesenchymal%20stem%20cells%20exert%20potent%20antitumorigenic%20effects%20in%20a%20model%20of%20Kaposi%E2%80%99s%20sarcoma&journal=J.%20Exp.%20Med.&doi=10.1084%2Fjem.20051921&volume=203&pages=1235-1247&publication_year=2006&author=Khakoo%2CAY bring in each month?
• Income figures for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12097260
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Bone%20marrow-derived%20mesenchymal%20stem%20cells%20as%20vehicles%20for%20interferon-%CE%B2%20delivery%20into%20tumors&journal=Cancer%20Res.&volume=62&pages=3603-3608&publication_year=2002&author=Studeny%2CM bring in?
• What are the total earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10493525?
• What's http://scholar.google.com/scholar_lookup?&title=Elevated%20expression%20of%20the%20CC%20chemokine%20regulated%20on%20activation%2C%20normal%20T%20cell%20expressed%20and%20secreted%20%28RANTES%29%20in%20advanced%20breast%20carcinoma&journal=Cancer%20Res.&volume=59&pages=4681-4687&publication_year=1999&author=Luboshits%2CG's gross income?
• How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11234881 produce monthly?
• How much money does http://scholar.google.com/scholar_lookup?&title=Correlation%20of%20tissue%20and%20plasma%20RANTES%20levels%20with%20disease%20course%20in%20patients%20with%20breast%20or%20cervical%20cancer&journal=Clin.%20Cancer%20Res.&volume=7&pages=285-289&publication_year=2001&author=Niwa%2CY make?
• What are the total earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11861388?
• http://scholar.google.com/scholar_lookup?&title=The%20CC%20chemokine%20RANTES%20in%20breast%20carcinoma%20progression%3A%20regulation%20of%20expression%20and%20potential%20mechanisms%20of%20promalignant%20activity&journal=Cancer%20Res.&volume=62&pages=1093-1102&publication_year=2002&author=Azenshtein%2CE's financial summary
• What's the income generated by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14678997 each month?
• Income figures for http://scholar.google.com/scholar_lookup?&title=A%20chemokine%20receptor%20antagonist%20inhibits%20experimental%20breast%20tumor%20growth&journal=Cancer%20Res.&volume=63&pages=8360-8365&publication_year=2003&author=Robinson%2CSC
• How much revenue does https://doi.org/10.1111%2Fj.1440-1711.2005.01345.x produce monthly?
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Expression%20of%20chemokines%20on%20the%20surface%20of%20different%20human%20endothelia&journal=Immunol.%20Cell%20Biol.&doi=10.1111%2Fj.1440-1711.2005.01345.x&volume=83&pages=375-382&publication_year=2005&author=Hillyer%2CP&author=Male%2CD
• How much does https://doi.org/10.1038%2Fnrc822 pull in monthly?
• What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Epithelial-mesenchymal%20transitions%20in%20tumour%20progression&journal=Nature%20Rev.%20Cancer&doi=10.1038%2Fnrc822&volume=2&pages=442-454&publication_year=2002&author=Thiery%2CJP?
• Revenue of https://doi.org/10.1158%2F0008-5472.CAN-06-0743
• Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Akt%20signaling%20and%20cancer%3A%20surviving%20but%20not%20moving%20on&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-06-0743&volume=66&pages=3963-3966&publication_year=2006&author=Toker%2CA&author=Yoeli-Lerner%2CM
• What's the financial gain of https://doi.org/10.1111%2Fj.1349-7006.2005.00059.x?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Chemokines%20in%20tumor%20progression%20and%20metastasis&journal=Cancer%20Sci.&doi=10.1111%2Fj.1349-7006.2005.00059.x&volume=96&pages=317-322&publication_year=2005&author=Tanaka%2CT?
• What's the financial intake of https://doi.org/10.1093%2Fembo-reports%2Fkve027?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=A%20role%20for%20chemokine%20receptor%20transactivation%20in%20growth%20factor%20signaling&journal=EMBO%20Rep.&doi=10.1093%2Fembo-reports%2Fkve027&volume=2&pages=151-156&publication_year=2001&author=Mira%2CE bring in?
• How much does https://doi.org/10.1073%2Fpnas.232688199 gross monthly?
• How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2003PNAS..100..183Q pull in?
• What's http://scholar.google.com/scholar_lookup?&title=Inhibiting%20HIV-1%20infection%20in%20human%20T%20cells%20by%20lentiviral-mediated%20delivery%20of%20small%20interfering%20RNA%20against%20CCR5&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.232688199&volume=100&pages=183-188&publication_year=2003&author=Qin%2CXF&author=An%2CDS&author=Chen%2CIS&author=Baltimore%2CD's gross income?
• What's the income generated by https://doi.org/10.1371%2Fjournal.pbio.0030187 each month?
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Determination%20of%20stromal%20signatures%20in%20breast%20carcinoma&journal=PLoS%20Biol.&doi=10.1371%2Fjournal.pbio.0030187&volume=3&publication_year=2005&author=West%2CRB?
• How much does https://doi.org/10.1016%2Fj.ccr.2004.06.010 net monthly?
• Find out how much http://scholar.google.com/scholar_lookup?&title=Molecular%20characterization%20of%20the%20tumor%20microenvironment%20in%20breast%20cancer&journal=Cancer%20Cell&doi=10.1016%2Fj.ccr.2004.06.010&volume=6&pages=17-32&publication_year=2004&author=Allinen%2CM earns monthly
• How much revenue does https://doi.org/10.1038%2Fnrc1388 bring in?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Cancer%20and%20the%20chemokine%20network&journal=Nature%20Rev.%20Cancer&doi=10.1038%2Fnrc1388&volume=4&pages=540-550&publication_year=2004&author=Balkwill%2CF?
• How much revenue does https://doi.org/10.3233%2FBD-2007-26107 generate?
• How much does http://scholar.google.com/scholar_lookup?&title=Chemokine%20networks%20and%20breast%20cancer%20metastasis&journal=Breast%20Dis.&doi=10.3233%2FBD-2007-26107&volume=26&pages=75-85&publication_year=2006&author=Karnoub%2CAE&author=Weinberg%2CRA pull in monthly?
• How much does https://doi.org/10.1021%2Fjm060009x earn?
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Discovery%20and%20development%20of%20small-molecule%20chemokine%20coreceptor%20CCR5%20antagonists&journal=J.%20Med.%20Chem.&doi=10.1021%2Fjm060009x&volume=49&pages=2851-2857&publication_year=2006&author=Palani%2CA&author=Tagat%2CJR?
• What's the income of https://doi.org/10.1016%2Fj.cell.2005.02.034?
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Stromal%20fibroblasts%20present%20in%20invasive%20human%20breast%20carcinomas%20promote%20tumor%20growth%20and%20angiogenesis%20through%20elevated%20SDF-1%2FCXCL12%20secretion&journal=Cell&doi=10.1016%2Fj.cell.2005.02.034&volume=121&pages=335-348&publication_year=2005&author=Orimo%2CA is on a monthly basis
• How much profit does https://doi.org/10.1101%2Fgad.828901 make?
• Find out how much http://scholar.google.com/scholar_lookup?&title=Human%20breast%20cancer%20cells%20generated%20by%20oncogenic%20transformation%20of%20primary%20mammary%20epithelial%20cells&journal=Genes%20Dev.&doi=10.1101%2Fgad.828901&volume=15&pages=50-65&publication_year=2001&author=Elenbaas%2CB earns monthly
• How much does https://doi.org/10.1089%2F10763270260424105 rake in every month?
• Income figures for http://scholar.google.com/scholar_lookup?&title=Systematic%20analysis%20of%20reportedly%20distinct%20populations%20of%20multipotent%20bone%20marrow-derived%20stem%20cells%20reveals%20a%20lack%20of%20distinction&journal=Tissue%20Eng.&doi=10.1089%2F10763270260424105&volume=8&pages=739-751&publication_year=2002&author=Lodie%2CTA
• What's the income generated by https://doi.org/10.1038%2F22780 each month?
• Earnings of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1999Natur.400..464H
• How much does http://scholar.google.com/scholar_lookup?&title=Creation%20of%20human%20tumour%20cells%20with%20defined%20genetic%20elements&journal=Nature&doi=10.1038%2F22780&volume=400&pages=464-468&publication_year=1999&author=Hahn%2CWC bring in each month?
• https://doi.org/10.1073%2Fpnas.0401064101's revenue stream
• See how much http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2004PNAS..101.4966K makes per month
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Reconstruction%20of%20functionally%20normal%20and%20malignant%20human%20breast%20tissues%20in%20mice&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.0401064101&volume=101&pages=4966-4971&publication_year=2004&author=Kuperwasser%2CC
• What is the monthly revenue of https://doi.org/10.1016%2Fj.ccr.2006.01.013?
• http://scholar.google.com/scholar_lookup?&title=X%20chromosomal%20abnormalities%20in%20basal-like%20human%20breast%20cancer&journal=Cancer%20Cell&doi=10.1016%2Fj.ccr.2006.01.013&volume=9&pages=121-132&publication_year=2006&author=Richardson%2CAL's financial summary
• What's the revenue for https://citation-needed.springer.com/v2/references/10.1038/nature06188?format=refman&flavour=references?
• What's the financial intake of http://www.ncbi.nlm.nih.gov/geo?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Antoine%20E.%20Karnoub gross monthly?
• Find out how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Antoine%20E.%20Karnoub%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earns monthly
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ajeeta%20B.%20Dash make?
• See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ajeeta%20B.%20Dash%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
• Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Annie%20P.%20Vo
• What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Annie%20P.%20Vo%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Income figures for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Andrew%20Sullivan
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Andrew%20Sullivan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
• How much cash flow does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Mary%20W.%20Brooks have monthly?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Mary%20W.%20Brooks%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
• What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=George%20W.%20Bell?
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22George%20W.%20Bell%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en produce monthly?
• Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Andrea%20L.%20Richardson
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Andrea%20L.%20Richardson%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
• Explore the financials of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kornelia%20Polyak
• What is the monthly revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kornelia%20Polyak%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Get to know https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ross%20Tubo's earnings
• Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ross%20Tubo%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
• What's the financial outcome of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Robert%20A.%20Weinberg?
• Find out how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Robert%20A.%20Weinberg%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earns monthly
• How much does https://static-content.springer.com/esm/art%3A10.1038%2Fnature06188/MediaObjects/41586_2007_BFnature06188_MOESM15_ESM.pdf rake in every month?
• How much does https://s100.copyright.com/AppDispatchServlet?title=Mesenchymal%20stem%20cells%20within%20tumour%20stroma%20promote%20breast%20cancer%20metastasis&author=Antoine%20E.%20Karnoub%20et%20al&contentID=10.1038%2Fnature06188©right=Springer%20Nature%20Limited&publication=0028-0836&publicationDate=2007-10-04&publisherName=SpringerNature&orderBeanReset=true pull in?
• What's the financial gain of https://citation-needed.springer.com/v2/references/10.1038/nature06188?format=refman&flavour=citation?
• How much does https://doi.org/10.1186/s12964-023-01413-9 earn?
• What's the monthly money flow for https://doi.org/10.1186/s13058-024-01763-3?
• What's the monthly income of https://doi.org/10.1038/s41420-023-01793-4?
• Check the income stats for https://doi.org/10.1038/s41417-023-00693-0
• What are the earnings of https://doi.org/10.1007/s12015-024-10710-w?
• What are the earnings of https://www.protocols.io/?
• What's the income generated by https://www.natureindex.com/ each month?
• Monthly income for http://www.naturechina.com
• https://www.natureasia.com/ja-jp income

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Foundation
• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref