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nature portfolio hospital research foundation privacy policy liver tumor development bead-immobilized p21-binding domain advertising immune compromised nod/scid/γc−/− cancer stem/progenitor cell small-cell lung cancer social media author information authors dynamic nature marker-defined cs/pc subpopulations transient nature 0/ reprints figure 1b middle full size image nature nature 1994 nature 2004 nature 2007 nature 2010 nature 2005 aldh1a1-/cd133-/mutant p53 slow-cycling melanoma cells creative commons attribution-noncommercial cobble-stone epithelial morphology tumor-initiating cell propagation distinct cs/pc subpopulations author correspondence primary resected early-stage therapy-resistant tumor cells cs/pc subpopulations vary liver-lodged cancer cells drug-resistant side population cs/pc transition dynamically distinct cs/pc subpopulation anti-rac1 western blotting adherent sphere-forming conditions cancer stem cell middle panel multiple cs/pc subpopulations nscla cs/pc subpopulations single cs/pc subpopulations reveal relative rac1-gtp cytokine-induced killer cells stem cell marker regulate nf-κβ activity tumour cell growth initiating tumour growth

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• Cancer stem cells: mirage or reality?

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