NATURE . COM {}

Matching Content Categories {📚}

• Science
• Education
• Health & Fitness

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$63,100 per month
Our calculations suggest that Nature.com earns between $42,042 and $115,616 monthly online from display advertisements.

Keywords {🔍}

cells, expression, cancer, figure, cspc, cell, panel, lung, emt, subpopulations, article, nscla, tgfβ, rac, google, scholar, primary, cdpos, aldhhigh, cas, nonsp, left, activity, stem, supplementary, adenocarcinoma, increased, gene, nature, facs, csc, distinct, analysis, selfrenewal, cspcs, represent, plasticity, observed, determined, mice, transition, human, cscs, tumor, isolated, stained, colonization, compared, tumors, aldhlow,

Topics {✒️}

nature portfolio hospital research foundation privacy policy liver tumor development bead-immobilized p21-binding domain advertising immune compromised nod/scid/γc−/− cancer stem/progenitor cell small-cell lung cancer social media author information authors dynamic nature marker-defined cs/pc subpopulations transient nature 0/ reprints figure 1b middle full size image nature nature 1994 nature 2004 nature 2007 nature 2010 nature 2005 aldh1a1-/cd133-/mutant p53 slow-cycling melanoma cells creative commons attribution-noncommercial cobble-stone epithelial morphology tumor-initiating cell propagation distinct cs/pc subpopulations author correspondence primary resected early-stage therapy-resistant tumor cells cs/pc subpopulations vary liver-lodged cancer cells drug-resistant side population cs/pc transition dynamically distinct cs/pc subpopulation anti-rac1 western blotting adherent sphere-forming conditions cancer stem cell middle panel multiple cs/pc subpopulations nscla cs/pc subpopulations single cs/pc subpopulations reveal relative rac1-gtp cytokine-induced killer cells stem cell marker regulate nf-κβ activity tumour cell growth initiating tumour growth

Questions {❓}

• Cancer stem cells: mirage or reality?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Non-small cell lung cancer stem/progenitor cells are enriched in multiple distinct phenotypic subpopulations and exhibit plasticity
         description:Cancer stem cells (CSCs) represent a population of cancer cells that possess unique self-renewal and differentiation characteristics required for tumorigenesis and are resistant to chemotherapy-induced apoptosis. Lung CSCs can be enriched by several markers including drug-resistant side population (SP), CD133pos and ALDHhigh. Using human non-small cell lung adenocarcinoma cell lines and patient-derived primary tumor cells, we demonstrate that SP cells represent a subpopulation distinct from other cancer stem/progenitor cell (CS/PC) populations marked by CD133pos or ALDHhigh. The non-CS/PCs and CS/PCs of each subpopulation are interconvertible. Epithelial-mesenchymal transition (EMT) promotes the formation of CD133pos and ALDHhigh CS/PC subpopulations while suppressing the SP CS/PC subpopulation. Rac1 GTPase activity is significantly increased in cells that have undergone EMT, and targeting Rac1 is effective in inhibiting the dynamic conversion of non-CS/PCs to CS/PCs, as well as the CS/PC activity. These results imply that various subpopulations of CS/PCs and non-CS/PCs may achieve a stochastic equilibrium in a defined microenvironment, and eliminating multiple subpopulations of CS/PCs and effectively blocking non-CS/PC to CS/PC transition, by an approach such as targeting Rac1, can be a more effective therapy.
         datePublished:2012-07-19T00:00:00Z
         dateModified:2012-07-19T00:00:00Z
         pageStart:e352
         pageEnd:e352
         sameAs:https://doi.org/10.1038/cddis.2012.93
         keywords:
            Non-small-cell lung cancer
            lung cancer
            cancer stem cells
            Rac1
            EMT
            self-renewal
            plasticity
            Life Sciences
            general
            Biochemistry
            Cell Biology
            Immunology
            Cell Culture
            Antibodies
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig5_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig6_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig7_HTML.jpg
         isPartOf:
            name:Cell Death & Disease
            issn:
               2041-4889
            volumeNumber:3
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:S Akunuru
               affiliation:
                     name:Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati
                     address:
                        name:Division of Experimental Hematology and Cancer Biology, Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, USA
                        type:PostalAddress
                     type:Organization
                     name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati
                     address:
                        name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Q James Zhai
               affiliation:
                     name:University of Cincinnati
                     address:
                        name:Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Y Zheng
               affiliation:
                     name:Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati
                     address:
                        name:Division of Experimental Hematology and Cancer Biology, Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, USA
                        type:PostalAddress
                     type:Organization
                     name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati
                     address:
                        name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:1
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Non-small cell lung cancer stem/progenitor cells are enriched in multiple distinct phenotypic subpopulations and exhibit plasticity
      description:Cancer stem cells (CSCs) represent a population of cancer cells that possess unique self-renewal and differentiation characteristics required for tumorigenesis and are resistant to chemotherapy-induced apoptosis. Lung CSCs can be enriched by several markers including drug-resistant side population (SP), CD133pos and ALDHhigh. Using human non-small cell lung adenocarcinoma cell lines and patient-derived primary tumor cells, we demonstrate that SP cells represent a subpopulation distinct from other cancer stem/progenitor cell (CS/PC) populations marked by CD133pos or ALDHhigh. The non-CS/PCs and CS/PCs of each subpopulation are interconvertible. Epithelial-mesenchymal transition (EMT) promotes the formation of CD133pos and ALDHhigh CS/PC subpopulations while suppressing the SP CS/PC subpopulation. Rac1 GTPase activity is significantly increased in cells that have undergone EMT, and targeting Rac1 is effective in inhibiting the dynamic conversion of non-CS/PCs to CS/PCs, as well as the CS/PC activity. These results imply that various subpopulations of CS/PCs and non-CS/PCs may achieve a stochastic equilibrium in a defined microenvironment, and eliminating multiple subpopulations of CS/PCs and effectively blocking non-CS/PC to CS/PC transition, by an approach such as targeting Rac1, can be a more effective therapy.
      datePublished:2012-07-19T00:00:00Z
      dateModified:2012-07-19T00:00:00Z
      pageStart:e352
      pageEnd:e352
      sameAs:https://doi.org/10.1038/cddis.2012.93
      keywords:
         Non-small-cell lung cancer
         lung cancer
         cancer stem cells
         Rac1
         EMT
         self-renewal
         plasticity
         Life Sciences
         general
         Biochemistry
         Cell Biology
         Immunology
         Cell Culture
         Antibodies
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig5_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig6_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_Article_BFcddis201293_Fig7_HTML.jpg
      isPartOf:
         name:Cell Death & Disease
         issn:
            2041-4889
         volumeNumber:3
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:S Akunuru
            affiliation:
                  name:Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati
                  address:
                     name:Division of Experimental Hematology and Cancer Biology, Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, USA
                     type:PostalAddress
                  type:Organization
                  name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati
                  address:
                     name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Q James Zhai
            affiliation:
                  name:University of Cincinnati
                  address:
                     name:Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Y Zheng
            affiliation:
                  name:Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati
                  address:
                     name:Division of Experimental Hematology and Cancer Biology, Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, USA
                     type:PostalAddress
                  type:Organization
                  name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati
                  address:
                     name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:1
["Periodical","PublicationVolume"]:
      name:Cell Death & Disease
      issn:
         2041-4889
      volumeNumber:3
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati
      address:
         name:Division of Experimental Hematology and Cancer Biology, Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, USA
         type:PostalAddress
      name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati
      address:
         name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati, USA
         type:PostalAddress
      name:University of Cincinnati
      address:
         name:Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, USA
         type:PostalAddress
      name:Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati
      address:
         name:Division of Experimental Hematology and Cancer Biology, Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, USA
         type:PostalAddress
      name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati
      address:
         name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:S Akunuru
      affiliation:
            name:Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati
            address:
               name:Division of Experimental Hematology and Cancer Biology, Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, USA
               type:PostalAddress
            type:Organization
            name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati
            address:
               name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati, USA
               type:PostalAddress
            type:Organization
      name:Q James Zhai
      affiliation:
            name:University of Cincinnati
            address:
               name:Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, USA
               type:PostalAddress
            type:Organization
      name:Y Zheng
      affiliation:
            name:Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati
            address:
               name:Division of Experimental Hematology and Cancer Biology, Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, USA
               type:PostalAddress
            type:Organization
            name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati
            address:
               name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Division of Experimental Hematology and Cancer Biology, Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, USA
      name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati, USA
      name:Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, USA
      name:Division of Experimental Hematology and Cancer Biology, Children’s Hospital Research Foundation, Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, USA
      name:Molecular Developmental Biology Program, Children’s Hospital Research Foundation, University of Cincinnati, Cincinnati, USA

Social Networks {👍}(1)

• https://twitter.com/cddpress

External Links {🔗}(92)

• Get to know what's the income of https://doi.org/10.1016%2Fj.cell.2009.08.017
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Heterogeneity%20in%20cancer%3A%20cancer%20stem%20cells%20versus%20clonal%20evolution&journal=Cell&doi=10.1016%2Fj.cell.2009.08.017&volume=138&pages=822-829&publication_year=2009&author=Shackleton%2CM&author=Quintana%2CE&author=Fearon%2CER&author=Morrison%2CSJ is on a monthly basis
• What is the earnings of https://doi.org/10.1038%2Fsj.cdd.4402283?
• How profitable is http://scholar.google.com/scholar_lookup?&title=Identification%20and%20expansion%20of%20the%20tumorigenic%20lung%20cancer%20stem%20cell%20population&journal=Cell%20Death%20Differ&doi=10.1038%2Fsj.cdd.4402283&volume=15&pages=504-514&publication_year=2008&author=Eramo%2CA&author=Lotti%2CF&author=Sette%2CG&author=Pilozzi%2CE&author=Biffoni%2CM&author=Di%20Virgilio%2CA?
• Check the income stats for https://doi.org/10.1158%2F0008-5472.CAN-06-3557
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Side%20population%20in%20human%20lung%20cancer%20cell%20lines%20and%20tumors%20is%20enriched%20with%20stem-like%20cancer%20cells&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-06-3557&volume=67&pages=4827-4833&publication_year=2007&author=Ho%2CMM&author=Ng%2CAV&author=Lam%2CS&author=Hung%2CJY is on a monthly basis
• What's the profit of https://doi.org/10.1016%2Fj.ijrobp.2011.06.1999?
• What's the revenue for http://scholar.google.com/scholar_lookup?&title=Role%20of%20insulin-like%20growth%20factor-1%20signaling%20pathway%20in%20Cisplatin-resistant%20lung%20cancer%20cells&journal=Int%20J%20Radiat%20Oncol%20Biol%20Phys&doi=10.1016%2Fj.ijrobp.2011.06.1999&volume=82&pages=e563-e572&publication_year=2012&author=Sun%2CY&author=Zheng%2CS&author=Torossian%2CA&author=Speirs%2CCK&author=Schleicher%2CS&author=Giacalone%2CNJ?
• What's https://doi.org/10.1038%2F367645a0's gross income?
• Find out how much http://scholar.google.com/scholar_lookup?&title=A%20cell%20initiating%20human%20acute%20myeloid%20leukaemia%20after%20transplantation%20into%20SCID%20mice&journal=Nature&doi=10.1038%2F367645a0&volume=367&pages=645-648&publication_year=1994&author=Lapidot%2CT&author=Sirard%2CC&author=Vormoor%2CJ&author=Murdoch%2CB&author=Hoang%2CT&author=Caceres-Cortes%2CJ earns monthly
• What's the revenue for https://doi.org/10.1038%2Fnature03128?
• How much profit is http://scholar.google.com/scholar_lookup?&title=Identification%20of%20human%20brain%20tumour%20initiating%20cells&journal=Nature&doi=10.1038%2Fnature03128&volume=432&pages=396-401&publication_year=2004&author=Singh%2CSK&author=Hawkins%2CC&author=Clarke%2CID&author=Squire%2CJA&author=Bayani%2CJ&author=Hide%2CT making per month?
• How much revenue does https://doi.org/10.1073%2Fpnas.0530291100 produce monthly?
• See how much http://scholar.google.com/scholar_lookup?&title=Prospective%20identification%20of%20tumorigenic%20breast%20cancer%20cells&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.0530291100&volume=100&pages=3983-3988&publication_year=2003&author=Al-Hajj%2CM&author=Wicha%2CMS&author=Benito-Hernandez%2CA&author=Morrison%2CSJ&author=Clarke%2CMF makes per month
• How much money does https://doi.org/10.1038%2Fnature05372 make?
• Earnings of http://scholar.google.com/scholar_lookup?&title=A%20human%20colon%20cancer%20cell%20capable%20of%20initiating%20tumour%20growth%20in%20immunodeficient%20mice&journal=Nature&doi=10.1038%2Fnature05372&volume=445&pages=106-110&publication_year=2007&author=O%E2%80%B2Brien%2CCA&author=Pollett%2CA&author=Gallinger%2CS&author=Dick%2CJE
• How much does https://doi.org/10.1002%2Fhep.21227 generate monthly?
• http://scholar.google.com/scholar_lookup?&title=Side%20population%20purified%20from%20hepatocellular%20carcinoma%20cells%20harbors%20cancer%20stem%20cell-like%20properties&journal=Hepatology&doi=10.1002%2Fhep.21227&volume=44&pages=240-251&publication_year=2006&author=Chiba%2CT&author=Kita%2CK&author=Zheng%2CYW&author=Yokosuka%2CO&author=Saisho%2CH&author=Iwama%2CA's revenue stream
• What's the revenue for https://doi.org/10.1371%2Fjournal.pone.0016951?
• How much money does http://scholar.google.com/scholar_lookup?&title=Rac1%20targeting%20suppresses%20human%20non-small%20cell%20lung%20adenocarcinoma%20cancer%20stem%20cell%20activity&journal=PLoS%20One&doi=10.1371%2Fjournal.pone.0016951&volume=6&publication_year=2011&author=Akunuru%2CS&author=Palumbo%2CJ&author=Zhai%2CQJ&author=Zheng%2CY make?
• How much does https://doi.org/10.1371%2Fjournal.pone.0003077 generate monthly?
• What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Drug-selected%20human%20lung%20cancer%20stem%20cells%3A%20cytokine%20network%2C%20tumorigenic%20and%20metastatic%20properties&journal=PLoS%20One&doi=10.1371%2Fjournal.pone.0003077&volume=3&publication_year=2008&author=Levina%2CV&author=Marrangoni%2CAM&author=DeMarco%2CR&author=Gorelik%2CE&author=Lokshin%2CAE?
• How much does https://doi.org/10.1371%2Fjournal.pone.0010277 generate monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=Distinct%20expression%20levels%20and%20patterns%20of%20stem%20cell%20marker%2C%20aldehyde%20dehydrogenase%20isoform%201%20%28ALDH1%29%2C%20in%20human%20epithelial%20cancers&journal=PLoS%20One&doi=10.1371%2Fjournal.pone.0010277&volume=5&publication_year=2010&author=Deng%2CS&author=Yang%2CX&author=Lassus%2CH&author=Liang%2CS&author=Kaur%2CS&author=Ye%2CQ gross monthly?
• How much does https://doi.org/10.1158%2F0008-5472.CAN-10-0881 bring in each month?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Aldehyde%20dehydrogenase%20activity%20selects%20for%20lung%20adenocarcinoma%20stem%20cells%20dependent%20on%20notch%20signaling&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-10-0881&volume=70&pages=9937-9948&publication_year=2010&author=Sullivan%2CJP&author=Spinola%2CM&author=Dodge%2CM&author=Raso%2CMG&author=Behrens%2CC&author=Gao%2CB generate?
• https://doi.org/10.1016%2Fj.cell.2009.06.034's total income per month
• What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Identification%20of%20selective%20inhibitors%20of%20cancer%20stem%20cells%20by%20high-throughput%20screening&journal=Cell&doi=10.1016%2Fj.cell.2009.06.034&volume=138&pages=645-659&publication_year=2009&author=Gupta%2CPB&author=Onder%2CTT&author=Jiang%2CG&author=Tao%2CK&author=Kuperwasser%2CC&author=Weinberg%2CRA?
• How much does https://doi.org/10.1016%2Fj.cell.2010.04.020 pull in?
• How much does http://scholar.google.com/scholar_lookup?&title=A%20temporarily%20distinct%20subpopulation%20of%20slow-cycling%20melanoma%20cells%20is%20required%20for%20continuous%20tumor%20growth&journal=Cell&doi=10.1016%2Fj.cell.2010.04.020&volume=141&pages=583-594&publication_year=2010&author=Roesch%2CA&author=Fukunaga-Kalabis%2CM&author=Schmidt%2CEC&author=Zabierowski%2CSE&author=Brafford%2CPA&author=Vultur%2CA generate monthly?
• How much does https://doi.org/10.1038%2Fnm0909-1010 earn?
• Financial intake of http://scholar.google.com/scholar_lookup?&title=Cancer%20stem%20cells%3A%20mirage%20or%20reality%3F&journal=Nat%20Med&doi=10.1038%2Fnm0909-1010&volume=15&pages=1010-1012&publication_year=2009&author=Gupta%2CPB&author=Chaffer%2CCL&author=Weinberg%2CRA
• How much profit does https://doi.org/10.1016%2Fj.cell.2008.03.027 generate?
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=The%20epithelial-mesenchymal%20transition%20generates%20cells%20with%20properties%20of%20stem%20cells&journal=Cell&doi=10.1016%2Fj.cell.2008.03.027&volume=133&pages=704-715&publication_year=2008&author=Mani%2CSA&author=Guo%2CW&author=Liao%2CMJ&author=Eaton%2CEN&author=Ayyanan%2CA&author=Zhou%2CAY
• What is the monthly revenue of https://doi.org/10.1073%2Fpnas.1006732107?
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Cancer%20stem%20cells%20from%20human%20breast%20tumors%20are%20involved%20in%20spontaneous%20metastases%20in%20orthotopic%20mouse%20models&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.1006732107&volume=107&pages=18115-18120&publication_year=2010&author=Liu%2CH&author=Patel%2CMR&author=Prescher%2CJA&author=Patsialou%2CA&author=Qian%2CD&author=Lin%2CJ?
• Learn how profitable https://doi.org/10.1158%2F0008-5472.CAN-05-3153 is on a monthly basis
• http://scholar.google.com/scholar_lookup?&title=Cancer%20stem%20cells%3A%20an%20old%20idea--a%20paradigm%20shift&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-05-3153&volume=66&pages=1883-1890&publication_year=2006&author=Wicha%2CMS&author=Liu%2CS&author=Dontu%2CG's revenue stream
• How much does https://doi.org/10.3346%2Fjkms.2007.22.5.898 make?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Transforming%20growth%20factor%20beta1%20induces%20epithelial-to-mesenchymal%20transition%20of%20A549%20cells&journal=J%20Korean%20Med%20Sci&doi=10.3346%2Fjkms.2007.22.5.898&volume=22&pages=898-904&publication_year=2007&author=Kim%2CJH&author=Jang%2CYS&author=Eom%2CKS&author=Hwang%2CYI&author=Kang%2CHR&author=Jang%2CSH
• How much money does https://doi.org/10.1016%2Fj.lungcan.2008.05.017 make?
• What is the earnings of http://scholar.google.com/scholar_lookup?&title=Epithelial%20to%20mesenchymal%20transition%20derived%20from%20repeated%20exposure%20to%20gefitinib%20determines%20the%20sensitivity%20to%20EGFR%20inhibitors%20in%20A549%2C%20a%20non-small%20cell%20lung%20cancer%20cell%20line&journal=Lung%20Cancer&doi=10.1016%2Fj.lungcan.2008.05.017&volume=63&pages=219-226&publication_year=2009&author=Rho%2CJK&author=Choi%2CYJ&author=Lee%2CJK&author=Ryoo%2CBY&author=Na%2CII&author=Yang%2CSH?
• How much does https://doi.org/10.1158%2F0008-5472.CAN-07-2545 pull in?
• How much does http://scholar.google.com/scholar_lookup?&title=ABCG2%20expression%20and%20side%20population%20abundance%20regulated%20by%20a%20transforming%20growth%20factor%20beta-directed%20epithelial-mesenchymal%20transition&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-07-2545&volume=68&pages=800-807&publication_year=2008&author=Yin%2CL&author=Castagnino%2CP&author=Assoian%2CRK pull in monthly?
• https://doi.org/10.1158%2F1078-0432.CCR-07-6735 income
• See how much http://scholar.google.com/scholar_lookup?&title=Snail%20up-regulates%20proinflammatory%20mediators%20and%20inhibits%20differentiation%20in%20oral%20keratinocytes&journal=Cancer%20Res&doi=10.1158%2F1078-0432.CCR-07-6735&volume=68&pages=4525-4530&publication_year=2008&author=Lyons%2CJG&author=Patel%2CV&author=Roue%2CNC&author=Fok%2CSY&author=Soon%2CLL&author=Halliday%2CGM makes per month
• How much does https://link.springer.com/doi/10.1007/s10585-010-9367-3 pull in?
• How much does http://scholar.google.com/scholar_lookup?&title=A%20systems%20view%20of%20epithelial-mesenchymal%20transition%20signaling%20states&journal=Clin%20Exp%20Metastasis&doi=10.1007%2Fs10585-010-9367-3&volume=28&pages=137-155&publication_year=2011&author=Thomson%2CS&author=Petti%2CF&author=Sujka-Kwok%2CI&author=Mercado%2CP&author=Bean%2CJ&author=Monaghan%2CM pull in?
• http://scholar.google.com/scholar_lookup?&title=Cross-talk%20between%20TGF-beta1%20and%20IL-6%20in%20human%20trabecular%20meshwork%20cells&journal=Mol%20Vision&volume=15&pages=326-334&publication_year=2009&author=Liton%2CPB&author=Li%2CG&author=Luna%2CC&author=Gonzalez%2CP&author=Epstein%2CDL's financial summary
• How much does https://doi.org/10.1002%2F%28SICI%291096-9896%28199705%29182%3A1%3C76%3A%3AAID-PATH805%3E3.0.CO%3B2-B net monthly?
• http://scholar.google.com/scholar_lookup?&title=Interleukin%206%20gene-transfected%20mouse%20mammary%20adenocarcinoma%3A%20tumour%20cell%20growth%20and%20metastatic%20potential&journal=J%20Pathol&doi=10.1002%2F%28SICI%291096-9896%28199705%29182%3A1%3C76%3A%3AAID-PATH805%3E3.0.CO%3B2-B&volume=182&pages=76-85&publication_year=1997&author=Di%20Carlo%2CE&author=Modesti%2CA&author=Castrilli%2CG&author=Landuzzi%2CL&author=Allione%2CA&author=de%20Giovanni%2CC's total income per month
• Find out how much https://doi.org/10.1038%2Fnature09161 earns monthly
• http://scholar.google.com/scholar_lookup?&title=Human%20melanoma-initiating%20cells%20express%20neural%20crest%20nerve%20growth%20factor%20receptor%20CD271&journal=Nature&doi=10.1038%2Fnature09161&volume=466&pages=133-137&publication_year=2010&author=Boiko%2CAD&author=Razorenova%2COV&author=van%20de%20Rijn%2CM&author=Swetter%2CSM&author=Johnson%2CDL&author=Ly%2CDP income
• Learn how profitable https://doi.org/10.1038%2F466040a is on a monthly basis
• Get to know http://scholar.google.com/scholar_lookup?&title=Cancer%20stem%20cells%3A%20invitation%20to%20a%20second%20round&journal=Nature&doi=10.1038%2F466040a&volume=466&pages=40-41&publication_year=2010&author=Dirks%2CP's earnings
• How much profit does https://doi.org/10.1073%2Fpnas.1018898108 generate?
• What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Inducible%20formation%20of%20breast%20cancer%20stem%20cells%20and%20their%20dynamic%20equilibrium%20with%20non-stem%20cancer%20cells%20via%20IL6%20secretion&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.1018898108&volume=108&pages=1397-1402&publication_year=2011&author=Iliopoulos%2CD&author=Hirsch%2CHA&author=Wang%2CG&author=Struhl%2CK?
• How much does https://doi.org/10.1016%2Fj.cell.2011.07.026 bring in each month?
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=Stochastic%20state%20transitions%20give%20rise%20to%20phenotypic%20equilibrium%20in%20populations%20of%20cancer%20cells&journal=Cell&doi=10.1016%2Fj.cell.2011.07.026&volume=146&pages=633-644&publication_year=2011&author=Gupta%2CPB&author=Fillmore%2CCM&author=Jiang%2CG&author=Shapira%2CSD&author=Tao%2CK&author=Kuperwasser%2CC have monthly?
• https://doi.org/10.1158%2F0008-5472.CAN-10-2638's total income per month
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Coexpression%20of%20Oct4%20and%20Nanog%20enhances%20malignancy%20in%20lung%20adenocarcinoma%20by%20inducing%20cancer%20stem%20cell-like%20properties%20and%20epithelial-mesenchymal%20transdifferentiation&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-10-2638&volume=70&pages=10433-10444&publication_year=2010&author=Chiou%2CSH&author=Wang%2CML&author=Chou%2CYT&author=Chen%2CCJ&author=Hong%2CCF&author=Hsieh%2CWJ?
• Learn how profitable https://doi.org/10.1073%2Fpnas.1009472107 is on a monthly basis
• How much money does http://scholar.google.com/scholar_lookup?&title=TGF-beta%20IL-6%20axis%20mediates%20selective%20and%20adaptive%20mechanisms%20of%20resistance%20to%20molecular%20targeted%20therapy%20in%20lung%20cancer&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.1009472107&volume=107&pages=15535-15540&publication_year=2010&author=Yao%2CZ&author=Fenoglio%2CS&author=Gao%2CDC&author=Camiolo%2CM&author=Stiles%2CB&author=Lindsted%2CT make?
• What's the monthly money flow for https://doi.org/10.1111%2Fj.1742-4658.2009.07031.x?
• What is the earnings of http://scholar.google.com/scholar_lookup?&title=Control%20of%20transforming%20growth%20factor%20beta%20signal%20transduction%20by%20small%20GTPases&journal=FEBS%20J&doi=10.1111%2Fj.1742-4658.2009.07031.x&volume=276&pages=2947-2965&publication_year=2009&author=Kardassis%2CD&author=Murphy%2CC&author=Fotsis%2CT&author=Moustakas%2CA&author=Stournaras%2CC?
• How much money does https://doi.org/10.1038%2Fnature03688 generate?
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Rac1b%20and%20reactive%20oxygen%20species%20mediate%20MMP-3-induced%20EMT%20and%20genomic%20instability&journal=Nature&doi=10.1038%2Fnature03688&volume=436&pages=123-127&publication_year=2005&author=Radisky%2CDC&author=Levy%2CDD&author=Littlepage%2CLE&author=Liu%2CH&author=Nelson%2CCM&author=Fata%2CJE is on a monthly basis
• What's the financial gain of https://doi.org/10.1016%2Fj.febslet.2010.03.042?
• See how much http://scholar.google.com/scholar_lookup?&title=Rac1%20modulates%20TGF-beta1-mediated%20epithelial%20cell%20plasticity%20and%20MMP9%20production%20in%20transformed%20keratinocytes&journal=FEBS%20Lett&doi=10.1016%2Fj.febslet.2010.03.042&volume=584&pages=2305-2310&publication_year=2010&author=Santibanez%2CJF&author=Kocic%2CJ&author=Fabra%2CA&author=Cano%2CA&author=Quintanilla%2CM makes per month
• How much profit does https://doi.org/10.1084%2Fjem.183.4.1797 generate?
• How much does http://scholar.google.com/scholar_lookup?&title=Isolation%20and%20functional%20properties%20of%20murine%20hematopoietic%20stem%20cells%20that%20are%20replicating%20in%20vivo&journal=J%20Exp%20Med&doi=10.1084%2Fjem.183.4.1797&volume=183&pages=1797-1806&publication_year=1996&author=Goodell%2CMA&author=Brose%2CK&author=Paradis%2CG&author=Conner%2CAS&author=Mulligan%2CRC net monthly?
• https://doi.org/10.1074%2Fjbc.M300341200's financial summary
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=p19Arf-p53%20tumor%20suppressor%20pathway%20regulates%20cell%20motility%20by%20suppression%20of%20phosphoinositide%203-kinase%20and%20Rac1%20GTPase%20activities&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.M300341200&volume=278&pages=14414-14419&publication_year=2003&author=Guo%2CF&author=Gao%2CY&author=Wang%2CL&author=Zheng%2CY?
• How much does https://citation-needed.springer.com/v2/references/10.1038/cddis.2012.93?format=refman&flavour=references pull in monthly?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=S%20Akunuru produce monthly?
• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22S%20Akunuru%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
• What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Q%20James%20Zhai each month?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Q%20James%20Zhai%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
• What's the revenue for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Y%20Zheng?
• What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Y%20Zheng%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
• What's the monthly income of https://static-content.springer.com/esm/art%3A10.1038%2Fcddis.2012.93/MediaObjects/41419_2012_BFcddis201293_MOESM65_ESM.pdf?
• What's the total monthly financial gain of https://s100.copyright.com/AppDispatchServlet?title=Non-small%20cell%20lung%20cancer%20stem%2Fprogenitor%20cells%20are%20enriched%20in%20multiple%20distinct%20phenotypic%20subpopulations%20and%20exhibit%20plasticity&author=S%20Akunuru%20et%20al&contentID=10.1038%2Fcddis.2012.93©right=The%20Author%28s%29&publication=2041-4889&publicationDate=2012-07-19&publisherName=SpringerNature&orderBeanReset=true&oa=CC%20BY-NC-ND?
• https://citation-needed.springer.com/v2/references/10.1038/cddis.2012.93?format=refman&flavour=citation's revenue stream
• How much does https://doi.org/10.1186/s12885-020-06818-0 net monthly?
• How much profit is https://doi.org/10.1007/s12015-020-10031-8 making per month?
• How much does https://doi.org/10.1186/s12957-016-1094-z net monthly?
• What's the financial outcome of https://doi.org/10.1038/s41598-017-04756-9?
• How much income is https://doi.org/10.1007/s00428-016-2057-z earning monthly?
• Check the income stats for https://www.protocols.io/
• Get to know https://www.natureindex.com/'s earnings
• How much cash flow does http://www.naturechina.com have monthly?
• Explore the financials of https://www.natureasia.com/ja-jp

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref