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cells, irs, cell, igfir, cancer, breast, growth, igfi, receptor, expression, tdya, article, google, scholar, tdyairs, cas, motility, insulin, substrate, insulinlike, data, activation, sfm, proliferation, yee, shown, figure, signalling, human, factor, usa, pathways, mapk, zhang, igfistimulated, lines, tdwt, protein, signaling, treated, proteins, αir, nature, mediate, functional, response, biological, adaptor, clinical, treatment,

Topics {✒️}

nature portfolio translational research privacy policy inhibit igf-i-stimulated entry nature 318 nature advertising growth factor-i-stimulated proliferation t47d-ya/irs-1 cells exhibited igf-i-stimulated cell proliferation measured igf-i-stimulated motility analysed igf-i-stimulated proliferation establish igf-ir-mediated monolayer mediate igf-ir-stimulated proliferation igf-i-activated igf-ir author information authors 0/ reprints t47d-ya/irs-1 cell clones t47d-ya/irs-2 cell clones induce igf-ir-mediated stimulation igf-ir-stimulated cell motility igf-ir-mediated cell motility igf-i-stimulated proliferation short-interfering rna constructs open bar pr-b-null-cell line investigate igf-ir-mediated proliferation igf-i-stimulated growth triple-negative breast cancer igf-i-stimulated motility mda-mb-231bo cells mda-mb-435 cell lines assessed anchorage-independent growth author correspondence igf-i-stimulated increase igf-ii influencing stability igf-ir stimulated proliferation igf-ir-stimulated proliferation antiprogestin-occupied b-receptors igf-ir signal transduction predict igf-ir dependency growth factor-mediated signaling high progesterone-receptor levels mediating igf-ir action 2 short-interfering rna anti-igf-ir agent igf-ir-mediated motility gold particle-coated coverslips disrupt igf-ir signalling igf-ir-stimulated behaviour

Questions {❓}

• This raises an important question: what molecular attributes will likely be predictive of tumour dependence on IGF-IR?

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