NATURE . COM {}

Matching Content Categories {📚}

• Science
• Education
• Telecommunications

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,194,993 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$531,700 per month
Estimations show Nature.com's display ad online revenue falls between $354,480 and $974,820 per month.

Keywords {🔍}

article, google, scholar, nature, cas, receptor, retinoid, access, receptors, rxr, ads, agonists, pparγ, cell, content, mice, insulin, retinoic, acid, ligand, cookies, hormone, center, usa, privacy, data, obese, thyroid, peroxisome, antidiabetic, signalling, diabetes, open, gene, evans, chem, science, california, research, diabetic, mukherjee, boehm, ligands, target, vitamin, response, umesono, nuclear, gamma, human,

Topics {✒️}

nature portfolio permissions reprints privacy policy cardiovascular research retinoid research advertising social media subscribe nature insulin-dependent diabetes mellitus nature 355 nature 358 nature 383 nature 345 nature 371 nature 372 nature 336 nature 386 nature single-function complex serving springerlink instant access rxr-selective agonists replicate permissions metabolic disorders induced rxr heterodimer-selective agonists personal data high affinity ligand retinoic acid receptors 9-cis retinoic acid promotes adipocyte differentiation ppar gamma diabetes gene encodes data protection data suggest leptin receptor gene insulin resistance privacy unique response pathways cognate response elements explore content subscription content uclear receptor lxrα european economic area regulate transcription1–6 institutional subscriptions read mouse obese gene alternative oxygen acceptor health science center human nutritional relevance suggested nutritional guidelines saad naunyn-schmiedeberg'

Questions {❓}

• We investigated whether RXR-selective agonists replicate the activity of ligands for several of these receptors?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
         description: Retinoic acid receptors (RAR), thyroid hormone receptors (TR), peroxisome proliferator activated receptors (PPARs) and the orphan receptor, LXR, bind preferentially to DNA as heterodimers with a common partner, retinoid X receptor (RXR), to regulate transcription1–6. We investigated whether RXR-selective agonists replicate the activity of ligands for several of these receptors? We demonstrate here that RXR-selective ligands (referred to as rexinoids) function as RXR heterodimer-selective agonists, activating RXR: PPARγ and RXR:LXR dimers but not RXR:RAR or RXR:TR heterodimers. Because PPARγ is a target for antidiabetic agents, we investigated whether RXR ligands could alter insulin and glucose signalling. In mouse models of non-insulin-dependent diabetes mellitus (NIDDM) and obesity, RXR agonists function as insulin sensitizers and can decrease hyperglycaemia, hypertriglyceridaemia and hyperinsulinaemia. This antidiabetic activity can be further enhanced by combination treatment with PPARγ agonists, such as thiazolidinediones. These data suggest that the RXR:PPARγ heterodimer is a single-function complex serving as a molecular target for treatment of insulin resistance. Activation of the RXR:PPARγ dimer with rexinoids may provide a new and effective treatment for NIDDM.
         datePublished:
         dateModified:
         pageStart:407
         pageEnd:410
         sameAs:https://doi.org/10.1038/386407a0
         keywords:
            Science
            Humanities and Social Sciences
            multidisciplinary
         image:
         isPartOf:
            name:Nature
            issn:
               1476-4687
               0028-0836
            volumeNumber:386
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Ranjan Mukherjee
               affiliation:
                     name:Ligand Pharmaceuticals
                     address:
                        name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Peter J. A. Davies
               type:Person
               name:Diane L. Crombie
               affiliation:
                     name:Ligand Pharmaceuticals
                     address:
                        name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Eric D. Bischoff
               affiliation:
                     name:Ligand Pharmaceuticals
                     address:
                        name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Rosemary M. Cesario
               affiliation:
                     name:Ligand Pharmaceuticals
                     address:
                        name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Lily Jow
               affiliation:
                     name:Ligand Pharmaceuticals
                     address:
                        name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Lawrence G. Hamann
               affiliation:
                     name:Ligand Pharmaceuticals
                     address:
                        name:Endocrine Chemistry, Ligand Pharmaceuticals, San Diego, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Marcus F. Boehm
               affiliation:
                     name:Ligand Pharmaceuticals
                     address:
                        name:Departments of Retinoid Chemistry, Ligand Pharmaceuticals, San Diego, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Carl E. Mondon
               type:Person
               name:Alex M. Nadzan
               affiliation:
                     name:Ligand Pharmaceuticals
                     address:
                        name:Departments of Retinoid Chemistry, Ligand Pharmaceuticals, San Diego, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:James R. Paterniti
               affiliation:
                     name:Ligand Pharmaceuticals
                     address:
                        name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Richard A. Heyman
               affiliation:
                     name:Ligand Pharmaceuticals
                     address:
                        name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
      description: Retinoic acid receptors (RAR), thyroid hormone receptors (TR), peroxisome proliferator activated receptors (PPARs) and the orphan receptor, LXR, bind preferentially to DNA as heterodimers with a common partner, retinoid X receptor (RXR), to regulate transcription1–6. We investigated whether RXR-selective agonists replicate the activity of ligands for several of these receptors? We demonstrate here that RXR-selective ligands (referred to as rexinoids) function as RXR heterodimer-selective agonists, activating RXR: PPARγ and RXR:LXR dimers but not RXR:RAR or RXR:TR heterodimers. Because PPARγ is a target for antidiabetic agents, we investigated whether RXR ligands could alter insulin and glucose signalling. In mouse models of non-insulin-dependent diabetes mellitus (NIDDM) and obesity, RXR agonists function as insulin sensitizers and can decrease hyperglycaemia, hypertriglyceridaemia and hyperinsulinaemia. This antidiabetic activity can be further enhanced by combination treatment with PPARγ agonists, such as thiazolidinediones. These data suggest that the RXR:PPARγ heterodimer is a single-function complex serving as a molecular target for treatment of insulin resistance. Activation of the RXR:PPARγ dimer with rexinoids may provide a new and effective treatment for NIDDM.
      datePublished:
      dateModified:
      pageStart:407
      pageEnd:410
      sameAs:https://doi.org/10.1038/386407a0
      keywords:
         Science
         Humanities and Social Sciences
         multidisciplinary
      image:
      isPartOf:
         name:Nature
         issn:
            1476-4687
            0028-0836
         volumeNumber:386
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Ranjan Mukherjee
            affiliation:
                  name:Ligand Pharmaceuticals
                  address:
                     name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Peter J. A. Davies
            type:Person
            name:Diane L. Crombie
            affiliation:
                  name:Ligand Pharmaceuticals
                  address:
                     name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Eric D. Bischoff
            affiliation:
                  name:Ligand Pharmaceuticals
                  address:
                     name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Rosemary M. Cesario
            affiliation:
                  name:Ligand Pharmaceuticals
                  address:
                     name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Lily Jow
            affiliation:
                  name:Ligand Pharmaceuticals
                  address:
                     name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Lawrence G. Hamann
            affiliation:
                  name:Ligand Pharmaceuticals
                  address:
                     name:Endocrine Chemistry, Ligand Pharmaceuticals, San Diego, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Marcus F. Boehm
            affiliation:
                  name:Ligand Pharmaceuticals
                  address:
                     name:Departments of Retinoid Chemistry, Ligand Pharmaceuticals, San Diego, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Carl E. Mondon
            type:Person
            name:Alex M. Nadzan
            affiliation:
                  name:Ligand Pharmaceuticals
                  address:
                     name:Departments of Retinoid Chemistry, Ligand Pharmaceuticals, San Diego, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:James R. Paterniti
            affiliation:
                  name:Ligand Pharmaceuticals
                  address:
                     name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Richard A. Heyman
            affiliation:
                  name:Ligand Pharmaceuticals
                  address:
                     name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature
      issn:
         1476-4687
         0028-0836
      volumeNumber:386
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Ligand Pharmaceuticals
      address:
         name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
         type:PostalAddress
      name:Ligand Pharmaceuticals
      address:
         name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
         type:PostalAddress
      name:Ligand Pharmaceuticals
      address:
         name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
         type:PostalAddress
      name:Ligand Pharmaceuticals
      address:
         name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
         type:PostalAddress
      name:Ligand Pharmaceuticals
      address:
         name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
         type:PostalAddress
      name:Ligand Pharmaceuticals
      address:
         name:Endocrine Chemistry, Ligand Pharmaceuticals, San Diego, USA
         type:PostalAddress
      name:Ligand Pharmaceuticals
      address:
         name:Departments of Retinoid Chemistry, Ligand Pharmaceuticals, San Diego, USA
         type:PostalAddress
      name:Ligand Pharmaceuticals
      address:
         name:Departments of Retinoid Chemistry, Ligand Pharmaceuticals, San Diego, USA
         type:PostalAddress
      name:Ligand Pharmaceuticals
      address:
         name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
         type:PostalAddress
      name:Ligand Pharmaceuticals
      address:
         name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Ranjan Mukherjee
      affiliation:
            name:Ligand Pharmaceuticals
            address:
               name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
               type:PostalAddress
            type:Organization
      name:Peter J. A. Davies
      name:Diane L. Crombie
      affiliation:
            name:Ligand Pharmaceuticals
            address:
               name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
               type:PostalAddress
            type:Organization
      name:Eric D. Bischoff
      affiliation:
            name:Ligand Pharmaceuticals
            address:
               name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
               type:PostalAddress
            type:Organization
      name:Rosemary M. Cesario
      affiliation:
            name:Ligand Pharmaceuticals
            address:
               name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
               type:PostalAddress
            type:Organization
      name:Lily Jow
      affiliation:
            name:Ligand Pharmaceuticals
            address:
               name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
               type:PostalAddress
            type:Organization
      name:Lawrence G. Hamann
      affiliation:
            name:Ligand Pharmaceuticals
            address:
               name:Endocrine Chemistry, Ligand Pharmaceuticals, San Diego, USA
               type:PostalAddress
            type:Organization
      name:Marcus F. Boehm
      affiliation:
            name:Ligand Pharmaceuticals
            address:
               name:Departments of Retinoid Chemistry, Ligand Pharmaceuticals, San Diego, USA
               type:PostalAddress
            type:Organization
      name:Carl E. Mondon
      name:Alex M. Nadzan
      affiliation:
            name:Ligand Pharmaceuticals
            address:
               name:Departments of Retinoid Chemistry, Ligand Pharmaceuticals, San Diego, USA
               type:PostalAddress
            type:Organization
      name:James R. Paterniti
      affiliation:
            name:Ligand Pharmaceuticals
            address:
               name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
               type:PostalAddress
            type:Organization
      name:Richard A. Heyman
      affiliation:
            name:Ligand Pharmaceuticals
            address:
               name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
      name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
      name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
      name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
      name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
      name:Endocrine Chemistry, Ligand Pharmaceuticals, San Diego, USA
      name:Departments of Retinoid Chemistry, Ligand Pharmaceuticals, San Diego, USA
      name:Departments of Retinoid Chemistry, Ligand Pharmaceuticals, San Diego, USA
      name:Departments of Cardiovascular Research, Ligand Pharmaceuticals, San Diego, USA
      name:Departments of Retinoid Research, Ligand Pharmaceuticals, San Diego, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

• https://www.facebook.com/Nature
• https://twitter.com/nature

External Links {🔗}(103)

• https://link.springer.com/article/10.1038/386407a0?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle's total income per month
• How much does https://doi.org/10.1016%2F0092-8674%2891%2990301-E rake in every month?
• Financial intake of http://scholar.google.com/scholar_lookup?&title=RXR%CE%B2%3A%20a%20coregulator%20that%20enhances%20binding%20of%20retinoic%20acid%2C%20thyroid%20hormone%2C%20and%20vitamin%20D%20receptors%20to%20their%20cognate%20response%20elements&journal=Cell&doi=10.1016%2F0092-8674%2891%2990301-E&volume=67&pages=1251-1266&publication_year=1991&author=Yu%2CVC
• How much cash flow does https://doi.org/10.1038%2F355441a0 have monthly?
• How much revenue does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1992Natur.355..441Z generate?
• How much does http://scholar.google.com/scholar_lookup?&title=Retinoid%20X%20receptor%20is%20an%20auxiliary%20protein%20for%20thyroid%20hormone%20and%20retinoic%20acid%20receptors&journal=Nature&doi=10.1038%2F355441a0&volume=355&pages=441-446&publication_year=1992&author=Zhang%2CXK&author=Hoffman%2CB&author=Tran%2CPB&author=Graupner%2CG&author=Pfahl%2CM net monthly?
• How much money does https://doi.org/10.1016%2F0092-8674%2892%2990478-U make?
• Profit of http://scholar.google.com/scholar_lookup?&title=Purification%2C%20cloning%2C%20and%20RXR%20identity%20of%20the%20HeLa%20cell%20factor%20with%20which%20RAR%20or%20TR%20heterodimerizes%20to%20bind%20target%20sequences%20efficiently&journal=Cell&doi=10.1016%2F0092-8674%2892%2990478-U&volume=68&pages=377-395&publication_year=1992&author=Leid%2CM
• Get to know https://doi.org/10.1038%2F355446a0's earnings
• What's the financial gain of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1992Natur.355..446K?
• How much does http://scholar.google.com/scholar_lookup?&title=Retinoid%20X%20receptor%20interacts%20with%20nuclear%20receptors%20in%20retinoic%20acid%2C%20thyroid%20hormone%20and%20vitamin%20D3%20signalling&journal=Nature&doi=10.1038%2F355446a0&volume=355&pages=446-449&publication_year=1992&author=Kliewer%2CSA&author=Umesono%2CK&author=Mangelsdorf%2CDJ&author=Evans%2CRM net monthly?
• How much income is https://doi.org/10.1038%2F358771a0 earning monthly?
• How much revenue does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1992Natur.358..771K bring in?
• Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Convergence%20of%209-cis%20retinoic%20acid%20and%20peroxisome%20proliferator%20signalling%20pathways%20through%20heterodimer%20formation%20of%20their%20receptors&journal=Nature&doi=10.1038%2F358771a0&volume=358&pages=771-774&publication_year=1992&author=Kliewer%2CSA&author=Umesono%2CK&author=Noonan%2CDJ&author=Heyman%2CRA&author=Evans%2CRM
• What's the financial intake of https://doi.org/10.1101%2Fgad.9.9.1033?
• http://scholar.google.com/scholar_lookup?&title=LXR%2C%20a%20nuclear%20receptor%20that%20defines%20a%20distinct%20retinoid%20response%20pathway&journal=Genes%20Dev.&doi=10.1101%2Fgad.9.9.1033&volume=9&pages=1033-1045&publication_year=1995&author=Willy%2CPJ's financial summary
• What's the financial gain of https://doi.org/10.1021%2Fjm00016a018?
• How much income does http://scholar.google.com/scholar_lookup?&title=Design%20and%20synthesis%20of%20potent%20retinoid%20X%20receptor%20selective%20ligands%20that%20induce%20apoptosis%20in%20leukemia%20cells&journal=J.%20Med.%20Chem.&doi=10.1021%2Fjm00016a018&volume=38&pages=3146-3155&publication_year=1995&author=Boehm%2CMF have?
• Earnings of https://doi.org/10.1021%2Fjm00044a014
• Find out how much http://scholar.google.com/scholar_lookup?&title=Synthesis%20and%20structure-activity%20relationships%20of%20novel%20retinoid%20X%20receptor%20selective%20retinoids&journal=J.%20Med.%20Chem.&doi=10.1021%2Fjm00044a014&volume=37&pages=2930-2941&publication_year=1994&author=Boehm%2CMF earns monthly
• What's the total monthly financial gain of https://doi.org/10.1038%2F383450a0?
• How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1996Natur.383..450L gross monthly?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Activation%20of%20specific%20RXR%20heterodimers%20by%20an%20antagonist%20of%20RXR%20homodimers&journal=Nature&doi=10.1038%2F383450a0&volume=383&pages=450-453&publication_year=1996&author=Lala%2CD generate?
• How much revenue does https://doi.org/10.1074%2Fjbc.270.22.12953 generate?
• How much does http://scholar.google.com/scholar_lookup?&title=An%20antidiabetic%20thiazolidinedione%20is%20a%20high%20affinity%20ligand%20for%20peroxisome%20proliferator-activated%20receptor%20gamma%20%28PPAR%20gamma%29&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.270.22.12953&volume=270&pages=12953-12956&publication_year=1995&author=Lehman%2CJM rake in every month?
• https://doi.org/10.1016%2F0092-8674%2895%2990194-9's revenue stream
• How much does http://scholar.google.com/scholar_lookup?&title=A%20prostaglandin%20J2%20metabolite%20binds%20peroxisome%20proliferator-activated%20receptor%20gamma%20and%20promotes%20adipocyte%20differentiation&journal=Cell&doi=10.1016%2F0092-8674%2895%2990194-9&volume=83&pages=813-819&publication_year=1995&author=Kliewer%2CSA bring in each month?
• Check the income stats for https://doi.org/10.1016%2F0092-8674%2895%2990193-0
• http://scholar.google.com/scholar_lookup?&title=15-Deoxy-delta%2012%2C14-postaglandin%20J2%20is%20a%20ligand%20for%20the%20adipocyte%20determination%20factor%20PPAR%20gamma&journal=Cell&doi=10.1016%2F0092-8674%2895%2990193-0&volume=83&pages=803-812&publication_year=1995&author=Forman%2CBM's revenue stream
• How profitable is https://doi.org/10.1038%2F383728a0?
• See how much http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1996Natur.383..728J makes per month
• Monthly income for http://scholar.google.com/scholar_lookup?&title=An%20oxysterol%20signalling%20pathway%20mediated%20by%20the%20uclear%20receptor%20LXR%CE%B1&journal=Nature&doi=10.1038%2F383728a0&volume=383&pages=728-731&publication_year=1996&author=Janowski%2CBA&author=Willy%2CPJ&author=Devi%2CTR&author=Falck%2CJR&author=Mangelsdorf%2CDJ
• https://doi.org/10.1038%2F345224a0's revenue stream
• How much money does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1990Natur.345..224M generate?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Nuclear%20receptor%20that%20identifies%20a%20novel%20retinoic%20acid%20response%20pathway&journal=Nature&doi=10.1038%2F345224a0&volume=345&pages=224-229&publication_year=1990&author=Mangelsdorf%2CDJ&author=Ong%2CES&author=Dyck%2CJA&author=Evans%2CRM make?
• What's https://doi.org/10.1038%2F371528a0's gross income?
• Earnings of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1994Natur.371..528K
• What's the income generated by http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20retinoid%20signalling%20by%20receptor%20polarity%20and%20allosteric%20control%20of%20ligand%20binding&journal=Nature&doi=10.1038%2F371528a0&volume=371&pages=528-531&publication_year=1994&author=Kurokawa%2CR each month?
• How much profit does https://doi.org/10.1016%2F0092-8674%2895%2990075-6 generate?
• How much does http://scholar.google.com/scholar_lookup?&title=Unique%20response%20pathways%20are%20established%20by%20allosteric%20interactions%20among%20nuclear%20hormone%20receptors&journal=Cell&doi=10.1016%2F0092-8674%2895%2990075-6&volume=81&pages=541-550&publication_year=1995&author=Forman%2CBM&author=Umesono%2CK&author=Chen%2CJ&author=Evans%2CRM generate monthly?
• What is the earnings of https://doi.org/10.1021%2Fjm950395a?
• Get to know http://scholar.google.com/scholar_lookup?&title=The%20structure-activity%20relationship%20between%20peroxisome%20proliferator-activated%20receptor%20%CE%B3%20agonism%20and%20the%20antihyperglycemic%20activity%20of%20thiazolidinediones&journal=J.%20Med.%20Chem.&doi=10.1021%2Fjm950395a&volume=39&pages=665-668&publication_year=1996&author=Willson%2CTM's earnings
• What's the revenue for https://link.springer.com/doi/10.1007/BF00429772?
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Obese%20and%20diabetes%3A%20two%20mutant%20genes%20causing%20diabetes-obesity%20syndromes%20in%20mice&journal=Diabetologia&doi=10.1007%2FBF00429772&volume=14&pages=141-148&publication_year=1978&author=Coleman%2CDL
• What's the revenue for https://doi.org/10.1093%2Foxfordjournals.jhered.a106073?
• What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Obese%2C%20a%20new%20mutation%20in%20the%20mouse&journal=J.%20Hered.&doi=10.1093%2Foxfordjournals.jhered.a106073&volume=41&publication_year=1950&author=Ingalls%2CAM&author=Dickie%2CMM&author=Snell%2CGD?
• What's the monthly income of https://doi.org/10.1038%2F372425a0?
• What's the financial outcome of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1994Natur.372..425Z?
• What's the income of http://scholar.google.com/scholar_lookup?&title=Positional%20cloning%20of%20the%20mouse%20obese%20gene%20and%20its%20human%20homologue&journal=Nature&doi=10.1038%2F372425a0&volume=372&pages=425-432&publication_year=1994&author=Zhang%2CY?
• What is the monthly revenue of https://doi.org/10.1016%2FS0092-8674%2800%2981294-5?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Evidence%20that%20the%20diabetes%20gene%20encodes%20the%20leptin%20receptor%3A%20identification%20of%20a%20mutation%20in%20the%20leptin%20receptor%20gene%20in%20db%2Fdb%20mice&journal=Cell&doi=10.1016%2FS0092-8674%2800%2981294-5&volume=84&pages=491-495&publication_year=1996&author=Chen%2CH generate?
• How much does https://doi.org/10.2337%2Fdiab.37.11.1549 pull in?
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Characterizaiton%20of%20new%20oral%20antidiabetic%20agent%20CS-045&journal=Diabetes&doi=10.2337%2Fdiab.37.11.1549&volume=37&pages=1549-1558&publication_year=1988&author=Fujiwara%2CT&author=Yoshioka%2CS&author=Yoshioka%2CT&author=Ushiyama%2CI&author=Horikoshi%2CH?
• How much does http://scholar.google.com/scholar_lookup?&title=Prevention%20of%20chemical%20carcinogenesis%20by%20vitamin%20A%20and%20its%20synthetic%20analogs%20%28retinoids%29&journal=Fed.%20Proc.&volume=35&pages=1332-1338&publication_year=1976&author=Sportn%2CMB&author=Dunlop%2CNM&author=Newton%2CDL&author=Smith%2CJM gross monthly?
• Revenue of https://doi.org/10.2337%2Fdiacare.15.2.193
• How much does http://scholar.google.com/scholar_lookup?&title=Metabolic%20effects%20of%20new%20oral%20hypoglycemic%20agent%20CS-045%20in%20NIDDM%20subjects&journal=Diabetes%20Care&doi=10.2337%2Fdiacare.15.2.193&volume=15&pages=193-203&publication_year=1992&author=Suter%2CSL&author=Nolan%2CJJ&author=Wallace%2CP&author=Gumbiner%2CB&author=Olefsky%2CJM make?
• How much revenue does https://doi.org/10.1074%2Fjbc.272.12.8071 bring in?
• How much money does http://scholar.google.com/scholar_lookup?&title=Identification%2C%20characterization%2C%20tissue%20distribution%20of%20human%20PPAR%CE%B32%20versus%20PPAR%CE%B31%20and%20activation%20with%20RXR%20agonists%20and%20antagonists&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.272.12.8071&volume=272&pages=8071-8076&publication_year=1997&author=Mukherjee%2CR&author=Jow%2CL&author=Croson%2CGE&author=Paterniti%2CJR generate?
• What are the earnings of https://doi.org/10.1038%2F336262a0?
• http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1988Natur.336..262U's total income per month
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Retinoic%20acid%20and%20thyroid%20hormone%20induce%20gene%20expression%20through%20a%20common%20responsive%20element&journal=Nature&doi=10.1038%2F336262a0&volume=336&pages=262-265&publication_year=1988&author=Umesono%2CK&author=Giguere%2CV&author=Glass%2CCK&author=Rosenfeld%2CMG&author=Evans%2CRM is on a monthly basis
• Revenue of https://doi.org/10.1016%2F0960-0760%2892%2990414-E
• http://scholar.google.com/scholar_lookup?&title=Interaction%20of%20glucocorticoid%20analogues%20with%20the%20human%20glucocorticoid%20receptor&journal=J.%20Steroid%20Biochem.%20Mol.%20Biol.&doi=10.1016%2F0960-0760%2892%2990414-E&volume=41&pages=733-738&publication_year=1992&author=Berger%2CTS&author=Parandoosh%2CZ&author=Perry%2CBW&author=Stein%2CRB's total income per month
• See how much https://doi.org/10.1177%2F000456326900600108 makes per month
• Earnings of http://scholar.google.com/scholar_lookup?&title=Determination%20of%20glucose%20in%20blood%20using%20glucose%20oxidase%20with%20an%20alternative%20oxygen%20acceptor&journal=Ann.%20Clin.%20Biochem.&doi=10.1177%2F000456326900600108&volume=6&pages=24-25&publication_year=1969&author=Trinder%2CD
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7015877 net monthly?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Enhanced%20skeletal%20muscle%20insulin%20sensitivity%20in%20year-old%20rats%20adapted%20to%20hypergravity&journal=Amer.%20J.%20Physiol&volume=240&pages=E482-488&publication_year=1981&author=Mondon%2CCE&author=Dolkas%2CCB&author=Oyama%2CJ generate?
• Explore the financials of https://citation-needed.springer.com/v2/references/10.1038/386407a0?format=refman&flavour=references
• What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ranjan%20Mukherjee?
• What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ranjan%20Mukherjee%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Peter%20J.%20A.%20Davies?
• What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Peter%20J.%20A.%20Davies%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Explore the financials of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Diane%20L.%20Crombie
• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Diane%20L.%20Crombie%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• What's the profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Eric%20D.%20Bischoff?
• Revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Eric%20D.%20Bischoff%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What's the monthly money flow for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Rosemary%20M.%20Cesario?
• What's https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Rosemary%20M.%20Cesario%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's gross income?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lily%20Jow's revenue stream
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lily%20Jow%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en rake in every month?
• Income figures for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lawrence%20G.%20Hamann
• How much profit is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lawrence%20G.%20Hamann%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en making per month?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Marcus%20F.%20Boehm rake in every month?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Marcus%20F.%20Boehm%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Carl%20E.%20Mondon rake in every month?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Carl%20E.%20Mondon%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
• How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Alex%20M.%20Nadzan making per month?
• What is the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Alex%20M.%20Nadzan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Get to know https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=James%20R.%20Paterniti's earnings
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22James%20R.%20Paterniti%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in?
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Richard%20A.%20Heyman make?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Richard%20A.%20Heyman%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in each month?
• Get to know what's the income of https://s100.copyright.com/AppDispatchServlet?title=Sensitization%20of%20diabetic%20and%20obese%20mice%20to%20insulin%20by%20retinoid%20X%20receptor%20agonists&author=Ranjan%20Mukherjee%20et%20al&contentID=10.1038%2F386407a0©right=Springer%20Nature%20Limited&publication=0028-0836&publicationDate=1997-03-27&publisherName=SpringerNature&orderBeanReset=true
• What's the financial outcome of https://citation-needed.springer.com/v2/references/10.1038/386407a0?format=refman&flavour=citation?
• What is the earnings of https://doi.org/10.1186/s12986-023-00750-3?
• Get to know https://doi.org/10.1038/s41419-022-04636-9's earnings
• What are the earnings of https://doi.org/10.1186/s12014-021-09328-8?
• What's the financial intake of https://doi.org/10.1038/s41598-021-89827-8?
• Find out how much https://doi.org/10.1007/s00210-020-01896-0 earns monthly
• Revenue of https://www.protocols.io/
• What's the income of https://www.natureindex.com/?
• How profitable is http://www.naturechina.com?
• What are the total earnings of https://www.natureasia.com/ja-jp?

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref