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Title:
Signal transduction to the permeability transition pore - PubMed
Description:
The permeability transition pore (PTP) is an inner mitochondrial membrane channel that has been thoroughly characterized functionally, yet remains an elusive molecular entity. The best characterized PTP-regulatory component, cyclophilin (CyP) D, is a matrix protein that favors pore opening. CyP inhi โฆ
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Keywords {๐}
mitochondrial, permeability, pmc, transition, doi, pore, pmid, pubmed, ptp, review, free, article, cell, bernardi, articles, epub, membrane, cyclophilin, forte, main, content, ncbi, similar, cited, references, mesh, resources, signal, transduction, role, disease, hexokinase, proteins, metabolism, ion, channels, zhang, wang, hhs, page, states, homepage, navigation, search, full, text, abstract, figures, publication, types,
Topics {โ๏ธ}
intracellular ion channels kinase/phosphatase signal transduction mitochondrial membrane channel mitochondrial permeability transition signal transduction permeability transition pore proteins involved main page content similar articles cited metabolism united states government null animals mitochondrial calcium uniporter funding linkout akt-erk-gsk3 axis permeability transition favors pore opening disease pathogenesis mitochondrial disorders mitochondrial pathophysiology characterized ptp-regulatory component cyclophilin d-mediated regulation elsevier review briefly covers 022 abstract elusive molecular entity european biochemical societies novartis found symp lรณpez de munain biochim biophys acta hypothermia-induced neuroprotection pubmed grimm pubmed wordmark pubmed logo cell culture conditions dynamin-related protein 1 mol cell cardiol synaptic mitochondria results pubmed wang situ ptp readouts hexokinase ii expression ptp signalling mechanisms cited hhs increased vulnerability kinase signalling 16167169 review 18074637 review review ptp regulation
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