
PUBMED . NCBI . NLM . NIH . GOV {
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Title:
Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species - PubMed
Description:
These findings indicate that the fission-mediated fragmentation of mitochondrial tubules is causally associated with enhanced production of mitochondrial ROS and cardiovascular cell injury in hyperglycaemic conditions.
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27 years and 8 months (reg. 1997-10-02).
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Keywords {π}
mitochondrial, doi, fission, cell, high, pmid, pmc, glucose, pubmed, mitochondria, free, article, death, reactive, oxygen, species, ros, conditions, nih, metabolism, states, role, cells, sustained, figure, heart, epub, cardiovascular, drug, hhsunited, main, articles, mesh, jul, production, yoon, morphology, levels, protein, increased, cardiac, kim, effects, ncbi, conflict, interest, similar, cited, references, types,
Topics {βοΈ}
united states government hhs main page content funding linkout reactive oxygen species hyperglycaemia-induced cell injury inhibiting mitochondrial fission stem-cell-derived cardiomyocytes animal dose-response relationship resources cardiovasc res literature sources similar articles cited cellular ros levels pubchem substance grants fission protein dlp1 drug dynamin mesh keyword fission-mediated fragmentation / metabolism endothelium promoting mitochondrial fission high glucose mitochondrial cell death cardiovascular cell injury subsequent cell death mitochondrial permeability transition physiol endocrinol metab mol biol cell pubmed bereiter-hahn protein dlp1 shey-shing sheu antioxid redox signal atrophied skeletal muscle leduc-gaudet jp int rev cytol heart fail rev evaluated mitochondrial morphology st-jean pelletier st-pierre dh mitochondrial fission maintaining tubular mitochondria glucose transport cultured disease models cell death mitochondrial ros mitochondrial tubules mitochondrial dysfunction aged mice increased production bovine cells cells incubated
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