PMC . NCBI . NLM . NIH . GOV {
}
We are analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC2646899/.
Title:
Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species - PMC
Description:
One of the main causes of cardiovascular complications in diabetes is the hyperglycemia-induced cell injury, and mitochondrial fission has been implicated in the apoptotic process. We investigated the role of mitochondrial fission in high ...
Website Age:
27 years and 9 months (reg. 1997-10-02).
Title:
Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species - PMC
Description:
One of the main causes of cardiovascular complications in diabetes is the hyperglycemia-induced cell injury, and mitochondrial fission has been implicated in the apoptotic process. We investigated the role of mitochondrial fission in high ...
Website Age:
27 years and 9 months (reg. 1997-10-02).
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Keywords {๐}
mitochondrial, glucose, cells, high, cell, doi, ros, conditions, death, fission, mitochondria, pubmed, google, scholar, incubation, fig, increased, mpt, levels, sustained, apoptosis, fragmentation, normal, morphology, fluorescence, increase, hyperglycemic, incubated, calcein, addlpka, biol, pmc, protein, concentration, fragmented, level, hours, showed, apoptotic, dlp, data, article, hour, dlpka, diabetes, results, fusion, injury, infected, free,
Topics {โ๏ธ}
ad-dlp1-k38a contained elongated ad-dlp1-k38a-infected cells show dominant-negative mutant dlp1-k38a dlp1-k38a-induced fission block beta-adrenergic receptor-stimulated apoptosis ad-dlp1-k38a infection abolished ad-dlp1-k38a-infected culture ad-dlp1-k38a-infected cells ad-dlp1-k38a exhibited anti-ฮฑ-actin antibody dominant-negative mutant form ad-dlp1-k38a infection hyperglycemia-induced inflammatory response cells expressing dlp1-k38a ad-dlp1-k38a showed dlp1-k38a/high glucose dynamin-related large gtpase 0ยตm calcein-acetomethoxy ester pmc beta search adding 30mm l-glucose annexin v-positive cells adenovirus carrying dlp1-k38a trypan blue-positive cells normalized caspase activities calcium-mediated mitochondrial fission hyperglycemia-induced cell death dynamin-related protein drp1 computer-assisted quantitative analyses fzo1-dependent fusion reaction dlp1-k38a virus-infected nih-developed imagej software hyperglycemia-induced cell injury hyperglycemia-induced ros overproduction high glucose-induced mpt major axis/minor axis 50 units/ml penicillin/streptomycin computer-assisted morphology analyses smooth muscle cells cell line h9c2 mouse monoclonal anti-cytochrome drp1-dependent division ad-dlp1-k38a control-infected cells shows dlp1-k38a expression cell death induced reactive oxygen species high glucose conditions hyperglycemia-induced death high glucose incubation protein dlp1/drp1
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