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LINK . SPRINGER . COM {}

Detected CMS Systems:

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Link.springer.com Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. CDN Services

We are analyzing https://link.springer.com/article/10.1186/gb-2011-12-6-r60.

Title:
Metagenomic biomarker discovery and explanation | Genome Biology
Description:
This study describes and validates a new method for metagenomic biomarker discovery by way of class comparison, tests of biological consistency and effect size estimation. This addresses the challenge of finding organisms, genes, or pathways that consistently explain the differences between two or more microbial communities, which is a central problem to the study of metagenomics. We extensively validate our method on several microbiomes and a convenient online interface for the method is provided at http://huttenhower.sph.harvard.edu/lefse/ .
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

  • Education
  • Science
  • Fitness & Wellness

Content Management System {📝}

What CMS is link.springer.com built with?


Link.springer.com utilizes PLONE.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 7,603,474 visitors per month in the current month.

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How Does Link.springer.com Make Money? {💸}

We see no obvious way the site makes money.

While profit motivates many websites, others exist to inspire, entertain, or provide valuable resources. Websites have a variety of goals. And this might be one of them. Link.springer.com has a secret sauce for making money, but we can't detect it yet.

Keywords {🔍}

pubmed, google, scholar, lefse, features, data, cas, class, classes, central, microbial, biomarkers, figure, metagenomic, samples, differences, human, analysis, effect, subclasses, body, biological, lda, size, sites, additional, communities, microbiome, file, comparison, microbiomes, disease, detected, gut, abundant, bacterial, statistical, false, test, metastats, tests, abundance, mucosal, subclass, biomarker, methods, nonmucosal, rag, clades, feature,

Topics {✒️}

nast-based sequence aligner ribosomal database project age-related macular degeneration 16s-based taxonomies/phylogenies high-dimensional biomarker discovery 16s-based phylometagenomic dataset high-dimensional data mining high-dimensional data spaces sequence read archive high-o2 exposure class high-throughput genetic data dana-farber cancer institute genome-wide association analysis publication-ready graphical results surprisingly condition-specific manners article number r60 post-weaning microbial specialization high-throughput gene mapping chronic intestinal inflammation linear discriminant analysis low-o2 exposure class transcriptional regulator/sugar kinase synthetic high-dimensional data high-performance comparative metagenomics genome-wide association study parametric factorial kruskal-wallis low-o2 specific genera high-dimensional genomic features inter-condition sample groupings previous culture-based studies article download pdf human microbiome project false-positive selection identified single clinical site user-friendly web application high-level functional roles linear discriminant axis low-throughput biological validations bacterial vaginosis [23] privacy choices/manage cookies potentially cosmetic products witten-bell smoothing [102] effect size estimation t-bet deficiency 16s rrna gene human microbiome consortium microbial ecology studies 454-pyrosequenced pcr amplicons genome-wide association additional genus-level clades

Questions {❓}

  • Pedrós-Alió C: Marine microbial diversity: can it be determined?
  • This problem is referred to as class comparison: how can the differences between phenotypes such as tumor subtype or disease state be explained in terms of consistent biological pathways or molecular mechanisms?
  • Young C, Sharma R, Handfield M, Mai V, Neu J: Biomarkers for infants at risk for necrotizing enterocolitis: clues to prevention?
  • Gov/Traces/sra/?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Metagenomic biomarker discovery and explanation
         description:This study describes and validates a new method for metagenomic biomarker discovery by way of class comparison, tests of biological consistency and effect size estimation. This addresses the challenge of finding organisms, genes, or pathways that consistently explain the differences between two or more microbial communities, which is a central problem to the study of metagenomics. We extensively validate our method on several microbiomes and a convenient online interface for the method is provided at http://huttenhower.sph.harvard.edu/lefse/ .
         datePublished:2011-06-24T00:00:00Z
         dateModified:2011-06-24T00:00:00Z
         pageStart:1
         pageEnd:18
         license:http://creativecommons.org/licenses/by/2.0/
         sameAs:https://doi.org/10.1186/gb-2011-12-6-r60
         keywords:
            Linear Discriminant Analysis
            Bacterial Vaginosis
            Body Site
            Effect Size Estimation
            Ribosomal Database Project
            Animal Genetics and Genomics
            Human Genetics
            Plant Genetics and Genomics
            Microbial Genetics and Genomics
            Bioinformatics
            Evolutionary Biology
         image:
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                        type:PostalAddress
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               name:Jacques Izard
               affiliation:
                     name:The Forsyth Institute
                     address:
                        name:Department of Molecular Genetics, The Forsyth Institute, Cambridge, USA
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                        name:Department of Medicine, Harvard Medical School, Boston, USA
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                        name:Department of Medical Oncology, Dana-Farber Cancer Institute, USA
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                     name:Harvard School of Public Health
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ScholarlyArticle:
      headline:Metagenomic biomarker discovery and explanation
      description:This study describes and validates a new method for metagenomic biomarker discovery by way of class comparison, tests of biological consistency and effect size estimation. This addresses the challenge of finding organisms, genes, or pathways that consistently explain the differences between two or more microbial communities, which is a central problem to the study of metagenomics. We extensively validate our method on several microbiomes and a convenient online interface for the method is provided at http://huttenhower.sph.harvard.edu/lefse/ .
      datePublished:2011-06-24T00:00:00Z
      dateModified:2011-06-24T00:00:00Z
      pageStart:1
      pageEnd:18
      license:http://creativecommons.org/licenses/by/2.0/
      sameAs:https://doi.org/10.1186/gb-2011-12-6-r60
      keywords:
         Linear Discriminant Analysis
         Bacterial Vaginosis
         Body Site
         Effect Size Estimation
         Ribosomal Database Project
         Animal Genetics and Genomics
         Human Genetics
         Plant Genetics and Genomics
         Microbial Genetics and Genomics
         Bioinformatics
         Evolutionary Biology
      image:
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         name:BioMed Central
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            type:ImageObject
         type:Organization
      author:
            name:Nicola Segata
            affiliation:
                  name:Harvard School of Public Health
                  address:
                     name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jacques Izard
            affiliation:
                  name:The Forsyth Institute
                  address:
                     name:Department of Molecular Genetics, The Forsyth Institute, Cambridge, USA
                     type:PostalAddress
                  type:Organization
                  name:Harvard School of Dental Medicine
                  address:
                     name:Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Levi Waldron
            affiliation:
                  name:Harvard School of Public Health
                  address:
                     name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Dirk Gevers
            affiliation:
                  name:The Broad Institute of MIT and Harvard
                  address:
                     name:Microbial Sequencing Center, The Broad Institute of MIT and Harvard, Cambridge, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Larisa Miropolsky
            affiliation:
                  name:Harvard School of Public Health
                  address:
                     name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Wendy S Garrett
            affiliation:
                  name:Harvard School of Public Health
                  address:
                     name:Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Harvard Medical School
                  address:
                     name:Department of Medicine, Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
                  name:Dana-Farber Cancer Institute
                  address:
                     name:Department of Medical Oncology, Dana-Farber Cancer Institute, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Curtis Huttenhower
            affiliation:
                  name:Harvard School of Public Health
                  address:
                     name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
                     type:PostalAddress
                  type:Organization
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         name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
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      address:
         name:Department of Molecular Genetics, The Forsyth Institute, Cambridge, USA
         type:PostalAddress
      name:Harvard School of Dental Medicine
      address:
         name:Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, USA
         type:PostalAddress
      name:Harvard School of Public Health
      address:
         name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
         type:PostalAddress
      name:The Broad Institute of MIT and Harvard
      address:
         name:Microbial Sequencing Center, The Broad Institute of MIT and Harvard, Cambridge, USA
         type:PostalAddress
      name:Harvard School of Public Health
      address:
         name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
         type:PostalAddress
      name:Harvard School of Public Health
      address:
         name:Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, USA
         type:PostalAddress
      name:Harvard Medical School
      address:
         name:Department of Medicine, Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Dana-Farber Cancer Institute
      address:
         name:Department of Medical Oncology, Dana-Farber Cancer Institute, USA
         type:PostalAddress
      name:Harvard School of Public Health
      address:
         name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
         type:PostalAddress
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      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Nicola Segata
      affiliation:
            name:Harvard School of Public Health
            address:
               name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
               type:PostalAddress
            type:Organization
      name:Jacques Izard
      affiliation:
            name:The Forsyth Institute
            address:
               name:Department of Molecular Genetics, The Forsyth Institute, Cambridge, USA
               type:PostalAddress
            type:Organization
            name:Harvard School of Dental Medicine
            address:
               name:Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, USA
               type:PostalAddress
            type:Organization
      name:Levi Waldron
      affiliation:
            name:Harvard School of Public Health
            address:
               name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
               type:PostalAddress
            type:Organization
      name:Dirk Gevers
      affiliation:
            name:The Broad Institute of MIT and Harvard
            address:
               name:Microbial Sequencing Center, The Broad Institute of MIT and Harvard, Cambridge, USA
               type:PostalAddress
            type:Organization
      name:Larisa Miropolsky
      affiliation:
            name:Harvard School of Public Health
            address:
               name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
               type:PostalAddress
            type:Organization
      name:Wendy S Garrett
      affiliation:
            name:Harvard School of Public Health
            address:
               name:Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, USA
               type:PostalAddress
            type:Organization
            name:Harvard Medical School
            address:
               name:Department of Medicine, Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
            name:Dana-Farber Cancer Institute
            address:
               name:Department of Medical Oncology, Dana-Farber Cancer Institute, USA
               type:PostalAddress
            type:Organization
      name:Curtis Huttenhower
      affiliation:
            name:Harvard School of Public Health
            address:
               name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
      name:Department of Molecular Genetics, The Forsyth Institute, Cambridge, USA
      name:Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, USA
      name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
      name:Microbial Sequencing Center, The Broad Institute of MIT and Harvard, Cambridge, USA
      name:Department of Biostatistics, Harvard School of Public Health, Boston, USA
      name:Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, USA
      name:Department of Medicine, Harvard Medical School, Boston, USA
      name:Department of Medical Oncology, Dana-Farber Cancer Institute, USA
      name:Department of Biostatistics, Harvard School of Public Health, Boston, USA

External Links {🔗}(305)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Prism.js

CDN Services {📦}

  • Crossref

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