We are analyzing https://link.springer.com/article/10.1186/1476-4598-10-38.

Title:
The functional role of long non-coding RNA in human carcinomas | Molecular Cancer
Description:
Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive pathways. These novel genes are frequently aberrantly expressed in a variety of human cancers, however the biological functions of the vast majority remain unknown. Recently, evidence has begun to accumulate describing the molecular mechanisms by which these RNA species function, providing insight into the functional roles they may play in tumorigenesis. In this review, we highlight the emerging functional role of lncRNAs in human cancer.
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Keywords {🔍}

pubmed, google, scholar, article, cas, rna, cancer, noncoding, central, expression, human, gene, cell, rnas, lncrna, genes, lncrnas, long, tumor, cells, transcription, res, role, genet, mol, biol, functional, expressed, xist, locus, chromosome, malat, transcripts, function, genome, transcript, breast, meg, cancers, nature, hulc, mirnas, figure, nat, regulation, silencing, suppressor, hotair, prostate, transcriptional,

Topics {✒️}

p16ink4a/p15ink4b-cdk4/6-prb pathways [177–179] 42kb ink4b-arf-ink4a locus mirna-mediated post-transcriptional regulation article download pdf post-transcriptional processing include silencing x-inactive-specific transcript aberrant transcription profiles imprinted dlk1-dio3 cluster intricate auto-regulatory network rna-directed chromatin asymmetry medicine pubmed search ink4b-arf-inka locus cell type-specific transcriptomes full size image polymer-based gene delivery ink4b-arf-ink4a locus apparently dicer-dependent manner human anti-nos2a locus human x-inactivation centre aberrant t-ucr expression x-linked gene expression open reading frame entire ink4/arf locus trna clover-leaf structure recurrent focal copy-number serum prostate-specific antigen x-inactivation center region microrna gene hsa-mir-9-1 post-transcriptional processing p53 transcriptional response x-inactive-specific transcript post-cleavage capping igf2-p4 regulatory sequences histone h3k36 trimethylation lncrna-mediated tumor suppression calin ga paired-end sequencing strategy monomeric alu element nuclear-localized tiny rnas small-cell lung cancer anril/prc mediated silencing conserved multi-exonic structure rna pol iii post-transcriptional silencing 'mirna sponge' mirrors cancer type-specific lncrnas study profiling t-ucrs anril-mediated tumor suppression molecular events leading rna pol ii

Questions {❓}

Huarte M, Rinn JL: Large non-coding RNAs: missing links in cancer?
Louro R, Smirnova AS, Verjovski-Almeida S: Long intronic noncoding RNA transcription: expression noise or expression choice?
Migeon BR: Is Tsix repression of Xist specific to mouse?
Ponting CP, Belgard TG: Transcribed dark matter: meaning or myth?

Schema {🗺️}

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         headline:The functional role of long non-coding RNA in human carcinomas
         description:Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive pathways. These novel genes are frequently aberrantly expressed in a variety of human cancers, however the biological functions of the vast majority remain unknown. Recently, evidence has begun to accumulate describing the molecular mechanisms by which these RNA species function, providing insight into the functional roles they may play in tumorigenesis. In this review, we highlight the emerging functional role of lncRNAs in human cancer.
         datePublished:2011-04-13T00:00:00Z
         dateModified:2011-04-13T00:00:00Z
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            lncRNA Expression
            lncRNA Gene
            XIST Expression
            miRNA Sponge
            Cancer Research
            Oncology
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      headline:The functional role of long non-coding RNA in human carcinomas
      description:Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive pathways. These novel genes are frequently aberrantly expressed in a variety of human cancers, however the biological functions of the vast majority remain unknown. Recently, evidence has begun to accumulate describing the molecular mechanisms by which these RNA species function, providing insight into the functional roles they may play in tumorigenesis. In this review, we highlight the emerging functional role of lncRNAs in human cancer.
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         lncRNA Expression
         lncRNA Gene
         XIST Expression
         miRNA Sponge
         Cancer Research
         Oncology
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