NCBI . NLM . NIH . GOV {
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Title[redir]:
lncRNAs transactivate Staufen1-mediated mRNA decay by duplexing with 3'UTRs via Alu elements - PMC
Description:
Staufen1 (STAU1)-mediated mRNA decay (SMD) degrades translationally active mRNAs that bind the double-stranded (ds)RNA binding protein STAU1 within their 3
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Keywords {🔍}
mrna, fig, supplementary, sbsrna, alu, utr, doi, stau, smd, serpine, element, sirna, flj, mrnas, sbs, pmc, pubmed, google, scholar, cells, binding, basepairing, lncrnas, article, table, free, elements, abundance, rtsqpcr, data, control, protein, targets, level, upf, rna, hela, ncbi, sbsrnas, defined, presence, complementary, site, nlm, basepair, single, human, kcalmol, normal, lysates,
Topics {✒️}
�-sbsrna1 sirna-mediated increase �-sbsrna1-created sbs associates phcmv-mup reference plasmid org/cgi-bin/webrepeatmasker au-rich signature motif hela-cell protein-encoding transcripts repress c-myc expression pmc beta search protein-encoding gene expression shortening mrna half-lives increasing mrna half-life1 half-stau1 binding site �-sbsrna1-binding site �-sbsrna1 binding site mrna half-life measurements flag-ms2-hmgfp bound folding free energy pfluc-serpine1 3'utr fl single 3'utr alu-element formaldehyde-crosslinked hela cells mrna rt-sqpcr product �-sbsrna1-mediated reduction �alu”strious long ncrnas expressing ½-sbsrna1 sirna nuclear hela-cell fractions cells expressing ½-sbsrna1 �-sbsrna1 base-pairs �-sbsrna4 base-pair stau1 binding site fluc-serpine1 3'utr mrna protein-encoding transcripts flag-ms2-hmgfp methods summary rt-sqpcr data shown identify comparable structures fluc reporter mrnas pflag-ms2-hmgfp mediated mrna decay direct protein synthesis transiently expressed stau1-ha3 �-sbsrna1 sirna increased dsrna binding proteins selective rna binding abstract staufen1 mfold web server pale green boxes regulate gene expression license information pmcid upf1-dependent mechanism mrna-derived product
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