
LINK . SPRINGER . COM {
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Title:
Metabolic reprogramming as a continuous changing behavior of tumor cells | Tumor Biology
Description:
Malignant cells resist microenvironment stress and migrate into surrounding tissues in order to divide with the need to adapt their metabolic program. These changes, often strengthened by the tremendous liaison between hypoxia, low glucose, and acidosis, are not yet completely understood. The aim of this perspective is to re-organize a possible comprehensive scenario useful to identify the metabolism occurring in various tumor cell subpopulations endowed with different capabilities.
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Topics {โ๏ธ}
month download article/chapter francesca bianchiniย &ย lido calorini amp-activated protein kinase hypoxia-inducible factor 1alpha ancient energy gauge reciprocal metabolic reprogramming acidic extracellular microenvironment full article pdf privacy choices/manage cookies metabolic reprogramming article peppicelli enforce tumor regression tumor metabolism european economic area continuous changing behavior anomalous gene expression clowes memorial lecture antioxid redox signal gonzalez herrera kn istituto toscano tumori cancer cells give cancer metabolism nat rev cancer conditions privacy policy pericellular ph homeostasis clinical biomedical sciences cancer cell int mol cell biol nat cell biol cell cycle arrest cancer metastasis rev tumor stroma article log accepting optional cookies metabolism occurring glutamine metabolism intermediary metabolism glucose metabolism lido calorini main content log author information authors article cite high aerobic glycolysis reverse warburg effect journal finder publish tumor cells metabolic program metabolic systems check access gillies rj
Questions {โ}
- Why do cancers have high aerobic glycolysis?
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headline:Metabolic reprogramming as a continuous changing behavior of tumor cells
description:Malignant cells resist microenvironment stress and migrate into surrounding tissues in order to divide with the need to adapt their metabolic program. These changes, often strengthened by the tremendous liaison between hypoxia, low glucose, and acidosis, are not yet completely understood. The aim of this perspective is to re-organize a possible comprehensive scenario useful to identify the metabolism occurring in various tumor cell subpopulations endowed with different capabilities.
datePublished:2015-07-10T00:00:00Z
dateModified:2015-07-10T00:00:00Z
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Cancer metabolism
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Cancer Research
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headline:Metabolic reprogramming as a continuous changing behavior of tumor cells
description:Malignant cells resist microenvironment stress and migrate into surrounding tissues in order to divide with the need to adapt their metabolic program. These changes, often strengthened by the tremendous liaison between hypoxia, low glucose, and acidosis, are not yet completely understood. The aim of this perspective is to re-organize a possible comprehensive scenario useful to identify the metabolism occurring in various tumor cell subpopulations endowed with different capabilities.
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