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Title:
Bioinformatics in Gene and Genome Analysis | SpringerLink
Description:
Gene and genome analysis play important roles in molecular biology research and individualized medicine. Thanks to the development of sequencing techniques, sequencing data is getting more and more abundant, which requires bioinformatic tools to handle. As a...
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28 years and 1 months (reg. 1997-05-29).

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Sam B, Patrick ST (2013) What is next generation sequencing?

Schema {🗺️}

ScholarlyArticle:
      headline:Bioinformatics in Gene and Genome Analysis
      pageEnd:111
      pageStart:97
      image:https://media.springernature.com/w153/springer-static/cover/book/978-981-99-8401-5.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:Advances in Bioinformatics
         isbn:
            978-981-99-8401-5
            978-981-99-8400-8
         type:Book
      publisher:
         name:Springer Nature Singapore
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Nhat Le Bui
            affiliation:
                  name:International School, Vietnam National University
                  address:
                     name:Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, Vietnam
                     type:PostalAddress
                  type:Organization
                  name:International School, Vietnam National University
                  address:
                     name:Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Van-Quy Do
            affiliation:
                  name:International School, Vietnam National University
                  address:
                     name:Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Dinh-Toi Chu
            affiliation:
                  name:International School, Vietnam National University
                  address:
                     name:Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, Vietnam
                     type:PostalAddress
                  type:Organization
                  name:International School, Vietnam National University
                  address:
                     name:Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:Bioinformatics, Computational tools, Gene and genome analysis, Comparative analysis
      description:Gene and genome analysis play important roles in molecular biology research and individualized medicine. Thanks to the development of sequencing techniques, sequencing data is getting more and more abundant, which requires bioinformatic tools to handle. As a combination of computational methods, statistics, and molecular biology, bioinformatics is a bridge between sequencing data and clinical interpretation. Via a half of decade development, bioinformatics has obtained novel achievements in data storage, assembly’s speed and accuracy, variant identification, and friendly-to-user interfaces. In this chapter, we focus on the history and development of bioinformatics as well as introduced the principles and several popular computational tools for each step in the workflow of gene and genome analysis, including data generation, genome assembly, annotation, comparative analysis, variant calling, and finally interpretation. Since the genomes of prokaryotes are distinguished from eukaryotes, we also mentioned the differences in the data process between humans as well as animals and microorganisms.
      datePublished:2024
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      isbn:
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         978-981-99-8400-8
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      name:Springer Nature Singapore
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         type:ImageObject
      name:International School, Vietnam National University
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         type:PostalAddress
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         type:PostalAddress
      name:International School, Vietnam National University
      address:
         name:Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam
         type:PostalAddress
      name:International School, Vietnam National University
      address:
         name:Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, Vietnam
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Person:
      name:Nhat Le Bui
      affiliation:
            name:International School, Vietnam National University
            address:
               name:Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, Vietnam
               type:PostalAddress
            type:Organization
            name:International School, Vietnam National University
            address:
               name:Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam
               type:PostalAddress
            type:Organization
      name:Van-Quy Do
      affiliation:
            name:International School, Vietnam National University
            address:
               name:Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam
               type:PostalAddress
            type:Organization
      name:Dinh-Toi Chu
      affiliation:
            name:International School, Vietnam National University
            address:
               name:Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, Vietnam
               type:PostalAddress
            type:Organization
            name:International School, Vietnam National University
            address:
               name:Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, Vietnam
      name:Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam
      name:Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam
      name:Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, Vietnam
      name:Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam
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