We are analyzing https://link.springer.com/article/10.1007/s11255-023-03527-y.

Title:
NETosis and kidney disease: what do we know? | International Urology and Nephrology
Description:
Neutrophils are the most abundant leukocytes in the blood. They are rapidly mobilized from the circulation to sites of inflammation and/or infection. In affected tissues, neutrophils exhibit some dramatic antimicrobial functions, including degranulation, reactive oxygen species (ROS) production, phagocytosis, and formation of neutrophil extracellular traps (NETs). Like other cells of the immune system, after fulfilling their biological duties, they enter the path of death. Depending on the conditions, they may undergo different types of cell death (apoptosis, necrosis, necroptosis, autophagy, NETosis, and pyroptosis) that require the participation of multiple signaling pathways. NETosis is a unique neutrophil cell death mechanism that gives rise to different inflammatory and autoimmune pathological conditions. Recent studies have shown that NETosis also plays a role in the formation and/or progression of kidney diseases. This review discusses the underlying mechanism of NETosis and its relationship with some major kidney diseases in light of the current knowledge.
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Keywords {🔍}

pubmed, article, google, scholar, cas, neutrophil, extracellular, kidney, neutrophils, central, traps, immunol, netosis, wang, formation, vasculitis, death, renal, cell, role, trap, int, antineutrophil, cytoplasmic, nephrology, disease, inflammation, privacy, cookies, content, ozturk, diseases, access, res, lupus, arthritis, van, author, medicine, springer, information, publish, research, search, ilyas, blood, nets, injury, front, httpsdoiorgfimmu,

Topics {✒️}

month download article/chapter plasma cell-free dna anti-neutrophil cytoplasmic antibodies sex-dependent mechanisms involved van dam ls article international urology antineutrophil cytoplasmic antibody antineutrophil cytoplasmic antibody full article pdf neutrophil extracellular traps ripk3-mediated necroptosis histone h3 citrullination autoimmune small-vessel vasculitis privacy choices/manage cookies major kidney diseases apoptotic microparticles drive acute rheumatic fever ilyas ozturk systemic lupus erythematosus chronic kidney disease article alaygut van der vlag accepted manuscript version low density neutrophils additional information publisher' al-aubaidy ha cell death ischemic/reperfusion injuries remote organ injury assessing disease activity bahcesehir university faculty holds exclusive rights related subjects autophagy-related signalling european economic area dramatic antimicrobial functions reactive oxygen species multiple signaling pathways daily balancing act gutierrez-mercado yk canales-aguirre aa nikolic-paterson dj short-term treatment produce oxygen radicals morales-buenrostro le ethics declarations conflict article log active lupus nephritis saavedra-mayorga de portilla-de-buen

Questions {❓}

NETosis and kidney disease: what do we know?
NETosis and kidney disease: what do we know?
O’Sullivan KM, Holdsworth SR (2021) Neutrophil extracellular traps: a potential therapeutic target in MPO-ANCA associated vasculitis?
Yipp BG, Kubes P (2013) NETosis: how vital is it?

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