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Keywords {🔍}

reads, flash, overlap, read, length, pairs, assembly, fragment, genome, merged, pairedend, number, correctly, error, correct, size, data, shows, short, shera, human, assemblies, library, overlapping, merging, table, merge, results, contigs, ratio, open, shown, lengths, fragments, mismatch, incorrect, contig, simulated, figure, fig, sequencing, shorter, rate, total, oxford, errors, quality, pair, original, region,

Topics {✒️}

oxford university press oxford academic bioinformatics mathematics books journals university press partners google scholar latest including rna-seq data fast computational tool combines paired-end reads illumina paired-end sequencing generate paired-end reads paired-end sequence data article sign resulting paired-end reads merging paired-end reads volume 27 november 2011 1 introduction enhancing variant interpretation overlapping paired-end reads paired-end reads overlapping high-quality draft assemblies low-quality overlapping reads maryland view access accessibility contact flash-assisted assembly contained marketing citing articles paired-end libraries min-olap bases overlap illumina sequencing platforms illumina sequencing technology generation sequencing technologies default settings contig n50 size current illumina sequencers total contig size rapidly dropping cost heuristic scoring function single threaded mode sra accession srx007714 k-mer size network visualization york dermatologists warrnambool paired-end reads paired-end library dna sequencing technologies min-olap parameter error-free data numbers dropped dramatically short dna sequences error-free reads

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      name:FLASH: fast length adjustment of short reads to improve genome assemblies
      datePublished:2011-09-07
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      url:https://dx.doi.org/10.1093/bioinformatics/btr507
      inLanguage:en
      copyrightHolder:Oxford University Press
      copyrightYear:2025
      publisher:Oxford University Press
      author:
            name:Magoč, Tanja
            affiliation:McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
            type:Person
            name:Salzberg, Steven L.
            affiliation:McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
            type:Person
      description:Abstract. Motivation: Next-generation sequencing technologies generate very large numbers of short reads. Even with very deep genome coverage, short read l
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      headline:FLASH: fast length adjustment of short reads to improve genome assemblies
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      image:alt:Distribution of fragment lengths. The horizontal axis shows the fragment length, and the vertical axis shows the number of fragments of a given length. (a) Staphylococcus aureus. (b) Human chromosome 14.
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      affiliation:McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
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      affiliation:McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

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