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FLASH: fast length adjustment of short reads to improve genome assemblies | Bioinformatics | Oxford Academic
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Abstract. Motivation: Next-generation sequencing technologies generate very large numbers of short reads. Even with very deep genome coverage, short read l
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Keywords {🔍}
reads, flash, overlap, read, length, pairs, assembly, fragment, genome, merged, pairedend, number, correctly, error, correct, size, data, shows, short, shera, human, assemblies, library, overlapping, merging, table, merge, results, contigs, ratio, open, shown, lengths, fragments, mismatch, incorrect, contig, simulated, figure, fig, sequencing, shorter, rate, total, oxford, errors, quality, pair, original, region,
Topics {✒️}
oxford university press oxford academic bioinformatics mathematics books journals signature search ccrr university press partners google scholar latest dose-response transcriptomic analysis including rna-seq data fast computational tool combines paired-end reads illumina paired-end sequencing generate paired-end reads paired-end sequence data article sign resulting paired-end reads merging paired-end reads volume 27 november 2011 1 introduction enhancing variant interpretation overlapping paired-end reads paired-end reads overlapping high-quality draft assemblies low-quality overlapping reads maryland view access accessibility contact flash-assisted assembly contained marketing citing articles paired-end libraries min-olap bases overlap cited dose-l1000 illumina sequencing platforms illumina sequencing technology generation sequencing technologies default settings contig n50 size current illumina sequencers total contig size rapidly dropping cost heuristic scoring function single threaded mode sra accession srx007714 k-mer size interactive shiny application target-centric exploration user-friendly platform york dermatologists warrnambool paired-end reads paired-end library dna sequencing technologies
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ScholarlyArticle:
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id:https://academic.oup.com/bioinformatics/article/27/21/2957/217265
name:FLASH: fast length adjustment of short reads to improve genome assemblies
datePublished:2011-09-07
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url:https://dx.doi.org/10.1093/bioinformatics/btr507
inLanguage:en
copyrightHolder:Oxford University Press
copyrightYear:2025
publisher:Oxford University Press
author:
name:Magoč, Tanja
affiliation:McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
type:Person
name:Salzberg, Steven L.
affiliation:McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
type:Person
description:Abstract. Motivation: Next-generation sequencing technologies generate very large numbers of short reads. Even with very deep genome coverage, short read l
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siteName:OUP Academic
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headline:FLASH: fast length adjustment of short reads to improve genome assemblies
image:https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bioinformatics/27/21/10.1093_bioinformatics_btr507/1/m_bioinformatics_27_21_2957_f1.jpeg?Expires=1813926393&Signature=D7zVc0oWG9qcJsihSwP69iX5dCYYQ3oRWk2y6lrr4-8ZbZa6jUg29g1TeZO0R3a-pCgwj~s4Y-C~DE7IYuzX19zpATKCFco6t~Hruwfs9waoax7UKMY4NOD0SVNMWyM2qvZSWYt6AIvLXf4PBkI1g0umZWMIcZruq8YEEFlyoil5tu52LhJsuBgUcl6pDErPBx3qjBQ9Ik~0xcpva7DwAuYu-3n6ANfWbqFIj2pjZOJCmBYkgZpsNHFb-uLWTEo0IOLZwU9qz2vtnNOncsYOApb4X416q5x9R5oN6ouoyHS6c~-9GRdtbEJ6rgZeFM8HW5JzUvFacToA6gEuYHOuNQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA
image:alt:Distribution of fragment lengths. The horizontal axis shows the fragment length, and the vertical axis shows the number of fragments of a given length. (a) Staphylococcus aureus. (b) Human chromosome 14.
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Person:
name:Magoč, Tanja
affiliation:McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
name:Salzberg, Steven L.
affiliation:McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
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