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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://link.springer.com/article/10.1007/s12026-007-0084-1, but it redirected us to https://link.springer.com/article/10.1007/s12026-007-0084-1. The analysis below is for the second page.

Title[redir]:
Neutrophils and TRAIL: insights into BCG immunotherapy for bladder cancer | Immunologic Research
Description:
Bladder cancer is a huge economic burden on the healthcare system and is responsible for approximately 5% of all cancer deaths in humans. Mycobacterium bovis BCG-based therapy is the treatment of choice for superficial bladder cancer. Bacillus Calmette-Guerin (BCG) instillation in the bladder results in a massive local inflammatory response that has secondary antitumor properties. Recent studies have demonstrated that neutrophils present in the bladder after BCG instillation release large amounts of the apoptosis-inducing molecule TRAIL, as well as chemokines that recruit other immune cells, suggesting that neutrophils play a key role in the antitumor response to BCG therapy. This review discusses the impact of these findings on the understanding of the antitumor mechanisms underlying BCG-based immunotherapy for bladder cancer.

Matching Content Categories {πŸ“š}

  • Education
  • Health & Fitness
  • Science

Content Management System {πŸ“}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {πŸ“ˆ}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Doi.org Make Money? {πŸ’Έ}

We don’t know how the website earns money.

The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Doi.org has a revenue plan, but it's either invisible or we haven't found it.

Keywords {πŸ”}

google, scholar, article, cancer, trail, ligand, immunol, bladder, cells, cas, bcg, griffith, tumor, apoptosisinducing, human, cell, necrosis, neutrophils, receptor, apoptosis, immunotherapy, bacillus, calmetteguerin, iowa, nauseef, death, factorrelated, exp, med, antitumor, chen, smith, biol, urol, treatment, factor, neutrophil, pubmed, research, thomas, mycobacterium, tnfrelated, res, university, usa, privacy, cookies, content, simons, william,

Topics {βœ’οΈ}

tnf-related apoptosis-inducing ligand tumour necrosis factor high-resolution x-ray structure tumor necrosis factor month download article/chapter functional soluble trail/apo-2l fas ligand-induced apoptosis apoptosis-inducing molecule trail ifn-gamma-dependent suppression death-inducing signaling complex monocyte-mediated tumoricidal activity lamhamedi-cherradi se bacillus calmette-guerin bladder cancer patients bacille calmette-guerin recombinant apo2l/trail versions bladder tumor cells interferon-activated neutrophils store related subjects de boer ec bladder cancer published superficial bladder cancer degli-esposti ma activation-induced death trail-induced apoptosis trail-mediated apoptosis trail/apo-2 ligand subcutaneous tumor growth defective thymocyte apoptosis full article pdf privacy choices/manage cookies apo2 ligand/trail tumor immune escape apoptosis-mediating receptor cytotoxic ligand trail human neutrophil apoptosis cd4+ t-cell murine bladder mucosa cytotoxicity-dependent apo-1 dendritic cell secretion national cancer institute nk cell-mediated mouse peritoneal macrophages intravesical therapy mucosal cytokine network trail/apo-2l triggering cell death accelerated autoimmune diseases nadph oxidase activation bcg therapy

Questions {❓}

  • At the center of the immune universe?

Schema {πŸ—ΊοΈ}

WebPage:
      mainEntity:
         headline:Neutrophils and TRAIL: insights into BCG immunotherapy for bladder cancer
         description:Bladder cancer is a huge economic burden on the healthcare system and is responsible for approximately 5% of all cancer deaths in humans. Mycobacterium bovis BCG-based therapy is the treatment of choice for superficial bladder cancer. Bacillus Calmette-Guerin (BCG) instillation in the bladder results in a massive local inflammatory response that has secondary antitumor properties. Recent studies have demonstrated that neutrophils present in the bladder after BCG instillation release large amounts of the apoptosis-inducing molecule TRAIL, as well as chemokines that recruit other immune cells, suggesting that neutrophils play a key role in the antitumor response to BCG therapy. This review discusses the impact of these findings on the understanding of the antitumor mechanisms underlying BCG-based immunotherapy for bladder cancer.
         datePublished:2007-06-19T00:00:00Z
         dateModified:2007-06-19T00:00:00Z
         pageStart:79
         pageEnd:93
         sameAs:https://doi.org/10.1007/s12026-007-0084-1
         keywords:
            TRAIL
            Neutrophil
            PMN
            BCG
             Mycobacterium
            Immunology
            Allergology
            Medicine/Public Health
            general
            Internal Medicine
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            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12026-007-0084-1/MediaObjects/12026_2007_84_Fig2_HTML.gif
         isPartOf:
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                        type:PostalAddress
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      headline:Neutrophils and TRAIL: insights into BCG immunotherapy for bladder cancer
      description:Bladder cancer is a huge economic burden on the healthcare system and is responsible for approximately 5% of all cancer deaths in humans. Mycobacterium bovis BCG-based therapy is the treatment of choice for superficial bladder cancer. Bacillus Calmette-Guerin (BCG) instillation in the bladder results in a massive local inflammatory response that has secondary antitumor properties. Recent studies have demonstrated that neutrophils present in the bladder after BCG instillation release large amounts of the apoptosis-inducing molecule TRAIL, as well as chemokines that recruit other immune cells, suggesting that neutrophils play a key role in the antitumor response to BCG therapy. This review discusses the impact of these findings on the understanding of the antitumor mechanisms underlying BCG-based immunotherapy for bladder cancer.
      datePublished:2007-06-19T00:00:00Z
      dateModified:2007-06-19T00:00:00Z
      pageStart:79
      pageEnd:93
      sameAs:https://doi.org/10.1007/s12026-007-0084-1
      keywords:
         TRAIL
         Neutrophil
         PMN
         BCG
          Mycobacterium
         Immunology
         Allergology
         Medicine/Public Health
         general
         Internal Medicine
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12026-007-0084-1/MediaObjects/12026_2007_84_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12026-007-0084-1/MediaObjects/12026_2007_84_Fig2_HTML.gif
      isPartOf:
         name:Immunologic Research
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            1559-0755
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         name:Humana Press Inc
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                  name:University of Iowa
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                     name:Department of Urology, 3204 MERF, University of Iowa, Iowa City, USA
                     type:PostalAddress
                  type:Organization
                  name:University of Iowa
                  address:
                     name:Inflammation Program, University of Iowa, Iowa City, USA
                     type:PostalAddress
                  type:Organization
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            name:William M. Nauseef
            affiliation:
                  name:University of Iowa
                  address:
                     name:Inflammation Program, University of Iowa, Iowa City, USA
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                  type:Organization
                  name:University of Iowa
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                     name:Department of Medicine, University of Iowa, Iowa City, USA
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                  type:Organization
                  name:University of Iowa
                  address:
                     name:Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, USA
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                  name:VA Medical Center
                  address:
                     name:VA Medical Center, Iowa City, USA
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            name:Thomas S. Griffith
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                  name:University of Iowa
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                     name:Department of Urology, 3204 MERF, University of Iowa, Iowa City, USA
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                     name:Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, USA
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         type:PostalAddress
      name:University of Iowa
      address:
         name:Inflammation Program, University of Iowa, Iowa City, USA
         type:PostalAddress
      name:University of Iowa
      address:
         name:Inflammation Program, University of Iowa, Iowa City, USA
         type:PostalAddress
      name:University of Iowa
      address:
         name:Department of Medicine, University of Iowa, Iowa City, USA
         type:PostalAddress
      name:University of Iowa
      address:
         name:Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, USA
         type:PostalAddress
      name:VA Medical Center
      address:
         name:VA Medical Center, Iowa City, USA
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      name:University of Iowa
      address:
         name:Department of Urology, 3204 MERF, University of Iowa, Iowa City, USA
         type:PostalAddress
      name:University of Iowa
      address:
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         type:PostalAddress
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               name:Department of Urology, 3204 MERF, University of Iowa, Iowa City, USA
               type:PostalAddress
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            name:University of Iowa
            address:
               name:Inflammation Program, University of Iowa, Iowa City, USA
               type:PostalAddress
            type:Organization
      name:William M. Nauseef
      affiliation:
            name:University of Iowa
            address:
               name:Inflammation Program, University of Iowa, Iowa City, USA
               type:PostalAddress
            type:Organization
            name:University of Iowa
            address:
               name:Department of Medicine, University of Iowa, Iowa City, USA
               type:PostalAddress
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            name:University of Iowa
            address:
               name:Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, USA
               type:PostalAddress
            type:Organization
            name:VA Medical Center
            address:
               name:VA Medical Center, Iowa City, USA
               type:PostalAddress
            type:Organization
      name:Thomas S. Griffith
      affiliation:
            name:University of Iowa
            address:
               name:Department of Urology, 3204 MERF, University of Iowa, Iowa City, USA
               type:PostalAddress
            type:Organization
            name:University of Iowa
            address:
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      name:Department of Medicine, University of Iowa, Iowa City, USA
      name:Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, USA
      name:VA Medical Center, Iowa City, USA
      name:Department of Urology, 3204 MERF, University of Iowa, Iowa City, USA
      name:Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, USA
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External Links {πŸ”—}(192)

Analytics and Tracking {πŸ“Š}

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CDN Services {πŸ“¦}

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