Here's how DOI.ORG makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Schema
  9. External Links
  10. Analytics And Tracking
  11. Libraries
  12. Hosting Providers
  13. CDN Services

We began analyzing https://link.springer.com/article/10.1007/s11010-020-04043-8, but it redirected us to https://link.springer.com/article/10.1007/s11010-020-04043-8. The analysis below is for the second page.

Title[redir]:
Crocin and Metformin suppress metastatic breast cancer progression via VEGF and MMP9 downregulations: in vitro and in vivo studies | Molecular and Cellular Biochemistry
Description:
Metastatic breast cancer remains a serious health concern and numerous investigations recommended medicinal plants as a complementary therapy. Crocin is one of the known anticancer bio-component. Recently, the inhibitory effect of metformin has been studied on the various aspects of cancer. However, no study reported their combination effects on metastatic breast cancer. In the present study, we have assessed their anti-metastatic effects on in vitro and in vivo breast cancer models. Using MTT assay, scratch, and adhesion tests, we have evaluated the cytotoxic, anti-invasive and anti-adhesion effects of crocin and metformin on 4T1 cell line, respectively. Their protective effects and MMP9 as well as VEGF protein expression levels (Western blotting) investigated in the 4T1 murine breast cancer model. Our results showed that both crocin and metformin reduced cell viability, delayed scratch healing and inhibited the cell adhesion, in vitro. While crocin alone restored the mice’s weight reduction, crocin, metformin, and their combination significantly reduced the tumor volume size and enhanced animal survival rate in murine breast cancer model, responses that were associated with VEGF and MMP9 down-regulation. These findings suggest that a combination of crocin and metformin could serve as a novel therapeutic approach to enhance the effectiveness of metastatic breast cancer therapy.

Matching Content Categories {📚}

  • Education
  • Health & Fitness
  • Science

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Doi.org Make Money? {💸}

We see no obvious way the site makes money.

Not all websites are made for profit; some exist to inform or educate users. Or any other reason why people make websites. And this might be the case. Doi.org might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

pubmed, cancer, article, google, scholar, cas, breast, metformin, central, crocin, cell, metastasis, effects, cells, hoshyar, wang, university, abedini, human, biol, metastatic, molecular, mmp, study, oncol, med, birjand, department, research, anticancer, effect, tumor, saffron, int, zhang, privacy, cookies, content, data, information, progression, vegf, vitro, farahi, expression, model, clin, res, pathway, medical,

Topics {✒️}

cd19-chimeric antigen receptor-modified wnt/β-catenin pathway genes triple-negative breast cancer wnt/β-catenin signaling pathway month download article/chapter western blotting wnt/β-catenin pathway promotes cancer metastasis shahr-e-qods branch elham chamani metastatic breast cancer breast cancer cells vegf-vegfr1 signaling pathway breast cancer chemotherapy postmenopausal breast cancer full article pdf 4t1 cell line human gynecologic cancers de hoon jp privacy choices/manage cookies human gastric adenocarcinoma drives malignant progression global cancer statistics mohammad reza abedini anti-metastatic effects facilitates tumor metastasis author information authors molecular research center bmc cancer 13 cellular biochemistry aims related subjects metformin inhibits proliferation breast cancer melanoma cell metastasis anti-diabetic drug article farahi tumor volume size main extracellular matrix article molecular molecular genetics department human cancers anticancer bio-component michigan state university european economic area north indian women tjan-heijnen vc mda-mb-231 histone h1 structure h1–dna interaction bax/bcl-2 ratio

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Crocin and Metformin suppress metastatic breast cancer progression via VEGF and MMP9 downregulations: in vitro and in vivo studies
         description:Metastatic breast cancer remains a serious health concern and numerous investigations recommended medicinal plants as a complementary therapy. Crocin is one of the known anticancer bio-component. Recently, the inhibitory effect of metformin has been studied on the various aspects of cancer. However, no study reported their combination effects on metastatic breast cancer. In the present study, we have assessed their anti-metastatic effects on in vitro and in vivo breast cancer models. Using MTT assay, scratch, and adhesion tests, we have evaluated the cytotoxic, anti-invasive and anti-adhesion effects of crocin and metformin on 4T1 cell line, respectively. Their protective effects and MMP9 as well as VEGF protein expression levels (Western blotting) investigated in the 4T1 murine breast cancer model. Our results showed that both crocin and metformin reduced cell viability, delayed scratch healing and inhibited the cell adhesion, in vitro. While crocin alone restored the mice’s weight reduction, crocin, metformin, and their combination significantly reduced the tumor volume size and enhanced animal survival rate in murine breast cancer model, responses that were associated with VEGF and MMP9 down-regulation. These findings suggest that a combination of crocin and metformin could serve as a novel therapeutic approach to enhance the effectiveness of metastatic breast cancer therapy.
         datePublished:2021-04-30T00:00:00Z
         dateModified:2021-04-30T00:00:00Z
         pageStart:3341
         pageEnd:3351
         sameAs:https://doi.org/10.1007/s11010-020-04043-8
         keywords:
            Breast cancer
            Metastasis
            Crocin
            Metformin
            Western Blotting
            Biochemistry
            general
            Cardiology
            Cancer Research
            Medical Biochemistry
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11010-020-04043-8/MediaObjects/11010_2020_4043_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11010-020-04043-8/MediaObjects/11010_2020_4043_Fig2_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11010-020-04043-8/MediaObjects/11010_2020_4043_Fig3_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11010-020-04043-8/MediaObjects/11010_2020_4043_Fig4_HTML.png
         isPartOf:
            name:Molecular and Cellular Biochemistry
            issn:
               1573-4919
               0300-8177
            volumeNumber:476
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Ali Farahi
               affiliation:
                     name:Birjand University of Medical Sciences
                     address:
                        name:Student Research Committee and Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran
                        type:PostalAddress
                     type:Organization
                     name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
                     address:
                        name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mohammad Reza Abedini
               affiliation:
                     name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
                     address:
                        name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
                        type:PostalAddress
                     type:Organization
                     name:University of Ottawa School of Medicine
                     address:
                        name:Department of Cellular and Molecular Medicine, University of Ottawa School of Medicine, Ottawa, Canada
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Hossein Javdani
               affiliation:
                     name:Birjand University of Medical Sciences
                     address:
                        name:Student Research Committee and Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran
                        type:PostalAddress
                     type:Organization
                     name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
                     address:
                        name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Laleh Arzi
               affiliation:
                     name:Islamic Azad University
                     address:
                        name:Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Elham Chamani
               affiliation:
                     name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
                     address:
                        name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ramin Farhoudi
               affiliation:
                     name:Pasteur Institute of Iran, Research and Production Complex
                     address:
                        name:Department of Viral Vaccine Production, Pasteur Institute of Iran, Research and Production Complex, Karaj, Iran
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Nazanin Talebloo
               affiliation:
                     name:College of Human Medicine, Michigan State University
                     address:
                        name:Precision Health Program, Department of Radiology, College of Human Medicine, Michigan State University, East Lansing, USA
                        type:PostalAddress
                     type:Organization
                     name:College of Natural Science, Michigan State University
                     address:
                        name:Department of Chemistry, College of Natural Science, Michigan State University, East Lansing, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Reyhane Hoshyar
               url:http://orcid.org/0000-0001-7713-3897
               affiliation:
                     name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
                     address:
                        name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
                        type:PostalAddress
                     type:Organization
                     name:Michigan State University
                     address:
                        name:Microbiology and Molecular Genetics Department, Michigan State University, East Lansing, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Crocin and Metformin suppress metastatic breast cancer progression via VEGF and MMP9 downregulations: in vitro and in vivo studies
      description:Metastatic breast cancer remains a serious health concern and numerous investigations recommended medicinal plants as a complementary therapy. Crocin is one of the known anticancer bio-component. Recently, the inhibitory effect of metformin has been studied on the various aspects of cancer. However, no study reported their combination effects on metastatic breast cancer. In the present study, we have assessed their anti-metastatic effects on in vitro and in vivo breast cancer models. Using MTT assay, scratch, and adhesion tests, we have evaluated the cytotoxic, anti-invasive and anti-adhesion effects of crocin and metformin on 4T1 cell line, respectively. Their protective effects and MMP9 as well as VEGF protein expression levels (Western blotting) investigated in the 4T1 murine breast cancer model. Our results showed that both crocin and metformin reduced cell viability, delayed scratch healing and inhibited the cell adhesion, in vitro. While crocin alone restored the mice’s weight reduction, crocin, metformin, and their combination significantly reduced the tumor volume size and enhanced animal survival rate in murine breast cancer model, responses that were associated with VEGF and MMP9 down-regulation. These findings suggest that a combination of crocin and metformin could serve as a novel therapeutic approach to enhance the effectiveness of metastatic breast cancer therapy.
      datePublished:2021-04-30T00:00:00Z
      dateModified:2021-04-30T00:00:00Z
      pageStart:3341
      pageEnd:3351
      sameAs:https://doi.org/10.1007/s11010-020-04043-8
      keywords:
         Breast cancer
         Metastasis
         Crocin
         Metformin
         Western Blotting
         Biochemistry
         general
         Cardiology
         Cancer Research
         Medical Biochemistry
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11010-020-04043-8/MediaObjects/11010_2020_4043_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11010-020-04043-8/MediaObjects/11010_2020_4043_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11010-020-04043-8/MediaObjects/11010_2020_4043_Fig3_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11010-020-04043-8/MediaObjects/11010_2020_4043_Fig4_HTML.png
      isPartOf:
         name:Molecular and Cellular Biochemistry
         issn:
            1573-4919
            0300-8177
         volumeNumber:476
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Ali Farahi
            affiliation:
                  name:Birjand University of Medical Sciences
                  address:
                     name:Student Research Committee and Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran
                     type:PostalAddress
                  type:Organization
                  name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
                  address:
                     name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mohammad Reza Abedini
            affiliation:
                  name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
                  address:
                     name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
                     type:PostalAddress
                  type:Organization
                  name:University of Ottawa School of Medicine
                  address:
                     name:Department of Cellular and Molecular Medicine, University of Ottawa School of Medicine, Ottawa, Canada
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Hossein Javdani
            affiliation:
                  name:Birjand University of Medical Sciences
                  address:
                     name:Student Research Committee and Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran
                     type:PostalAddress
                  type:Organization
                  name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
                  address:
                     name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Laleh Arzi
            affiliation:
                  name:Islamic Azad University
                  address:
                     name:Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Elham Chamani
            affiliation:
                  name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
                  address:
                     name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ramin Farhoudi
            affiliation:
                  name:Pasteur Institute of Iran, Research and Production Complex
                  address:
                     name:Department of Viral Vaccine Production, Pasteur Institute of Iran, Research and Production Complex, Karaj, Iran
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Nazanin Talebloo
            affiliation:
                  name:College of Human Medicine, Michigan State University
                  address:
                     name:Precision Health Program, Department of Radiology, College of Human Medicine, Michigan State University, East Lansing, USA
                     type:PostalAddress
                  type:Organization
                  name:College of Natural Science, Michigan State University
                  address:
                     name:Department of Chemistry, College of Natural Science, Michigan State University, East Lansing, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Reyhane Hoshyar
            url:http://orcid.org/0000-0001-7713-3897
            affiliation:
                  name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
                  address:
                     name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
                     type:PostalAddress
                  type:Organization
                  name:Michigan State University
                  address:
                     name:Microbiology and Molecular Genetics Department, Michigan State University, East Lansing, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Molecular and Cellular Biochemistry
      issn:
         1573-4919
         0300-8177
      volumeNumber:476
Organization:
      name:Springer US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Birjand University of Medical Sciences
      address:
         name:Student Research Committee and Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran
         type:PostalAddress
      name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
      address:
         name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
         type:PostalAddress
      name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
      address:
         name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
         type:PostalAddress
      name:University of Ottawa School of Medicine
      address:
         name:Department of Cellular and Molecular Medicine, University of Ottawa School of Medicine, Ottawa, Canada
         type:PostalAddress
      name:Birjand University of Medical Sciences
      address:
         name:Student Research Committee and Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran
         type:PostalAddress
      name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
      address:
         name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
         type:PostalAddress
      name:Islamic Azad University
      address:
         name:Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
         type:PostalAddress
      name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
      address:
         name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
         type:PostalAddress
      name:Pasteur Institute of Iran, Research and Production Complex
      address:
         name:Department of Viral Vaccine Production, Pasteur Institute of Iran, Research and Production Complex, Karaj, Iran
         type:PostalAddress
      name:College of Human Medicine, Michigan State University
      address:
         name:Precision Health Program, Department of Radiology, College of Human Medicine, Michigan State University, East Lansing, USA
         type:PostalAddress
      name:College of Natural Science, Michigan State University
      address:
         name:Department of Chemistry, College of Natural Science, Michigan State University, East Lansing, USA
         type:PostalAddress
      name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
      address:
         name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
         type:PostalAddress
      name:Michigan State University
      address:
         name:Microbiology and Molecular Genetics Department, Michigan State University, East Lansing, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Ali Farahi
      affiliation:
            name:Birjand University of Medical Sciences
            address:
               name:Student Research Committee and Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran
               type:PostalAddress
            type:Organization
            name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
            address:
               name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
               type:PostalAddress
            type:Organization
      name:Mohammad Reza Abedini
      affiliation:
            name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
            address:
               name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
               type:PostalAddress
            type:Organization
            name:University of Ottawa School of Medicine
            address:
               name:Department of Cellular and Molecular Medicine, University of Ottawa School of Medicine, Ottawa, Canada
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Hossein Javdani
      affiliation:
            name:Birjand University of Medical Sciences
            address:
               name:Student Research Committee and Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran
               type:PostalAddress
            type:Organization
            name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
            address:
               name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
               type:PostalAddress
            type:Organization
      name:Laleh Arzi
      affiliation:
            name:Islamic Azad University
            address:
               name:Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
               type:PostalAddress
            type:Organization
      name:Elham Chamani
      affiliation:
            name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
            address:
               name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
               type:PostalAddress
            type:Organization
      name:Ramin Farhoudi
      affiliation:
            name:Pasteur Institute of Iran, Research and Production Complex
            address:
               name:Department of Viral Vaccine Production, Pasteur Institute of Iran, Research and Production Complex, Karaj, Iran
               type:PostalAddress
            type:Organization
      name:Nazanin Talebloo
      affiliation:
            name:College of Human Medicine, Michigan State University
            address:
               name:Precision Health Program, Department of Radiology, College of Human Medicine, Michigan State University, East Lansing, USA
               type:PostalAddress
            type:Organization
            name:College of Natural Science, Michigan State University
            address:
               name:Department of Chemistry, College of Natural Science, Michigan State University, East Lansing, USA
               type:PostalAddress
            type:Organization
      name:Reyhane Hoshyar
      url:http://orcid.org/0000-0001-7713-3897
      affiliation:
            name:Cellular and Molecular Research Center, Birjand University of Medical Sciences
            address:
               name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
               type:PostalAddress
            type:Organization
            name:Michigan State University
            address:
               name:Microbiology and Molecular Genetics Department, Michigan State University, East Lansing, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Student Research Committee and Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran
      name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
      name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
      name:Department of Cellular and Molecular Medicine, University of Ottawa School of Medicine, Ottawa, Canada
      name:Student Research Committee and Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran
      name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
      name:Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
      name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
      name:Department of Viral Vaccine Production, Pasteur Institute of Iran, Research and Production Complex, Karaj, Iran
      name:Precision Health Program, Department of Radiology, College of Human Medicine, Michigan State University, East Lansing, USA
      name:Department of Chemistry, College of Natural Science, Michigan State University, East Lansing, USA
      name:Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
      name:Microbiology and Molecular Genetics Department, Michigan State University, East Lansing, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(247)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Crossref

4.65s.