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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://link.springer.com/article/10.1007/s10911-009-9109-9, but it redirected us to https://link.springer.com/article/10.1007/s10911-009-9109-9. The analysis below is for the second page.

Title[redir]:
ABC Transporters, Drug Resistance, and Cancer Stem Cells | Journal of Mammary Gland Biology and Neoplasia
Description:
The protection of the body’s stem cells from damage or death due to toxins is a critical function of an organism, as the stem cells need to remain intact for the entire life of the organism. One of the principal mechanisms for protecting stem cells is through the expression of multifunctional efflux transporters from the ATP-binding cassette (ABC) gene family. These same transporters have been known for over 25 years to also play a role in multidrug resistance of tumor cells. An exciting outcome of the concept of the cancer stem cell is that the tumor initiating cell may be innately resistant to many standard therapies. This provides one mechanism in which cancer stem cells could survive cytotoxic or targeted therapies and lead to tumor regrowth or relapse. Gaining a better insight into the mechanisms of stem cell resistance to chemotherapy might therefore lead to new therapeutic targets and better anti-cancer strategies.

Matching Content Categories {📚}

  • Science
  • Education
  • Health & Fitness

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🏙️ Massive Traffic: 50M - 100M visitors per month


Based on our best estimate, this website will receive around 80,479,999 visitors per month in the current month.

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How Does Doi.org Make Money? {💸}

We don’t know how the website earns money.

Some websites aren't about earning revenue; they're built to connect communities or raise awareness. There are numerous motivations behind creating websites. This might be one of them. Doi.org might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

article, google, scholar, pubmed, cas, cells, cancer, stem, resistance, cell, abc, transporter, gene, res, multidrug, transporters, dean, population, human, atpbinding, cassette, side, abcg, mammary, drug, expression, protein, breast, tumor, biol, hematopoietic, privacy, cookies, content, journal, access, structure, rev, genes, transport, nature, pglycoprotein, bcrp, van, publish, search, gland, michael, efflux, mechanism,

Topics {✒️}

human atp-binding cassette month download article/chapter atp-binding cassette transporter aromatase inhibitor-resistant estrogen receptor expression multidrug-resistant cell lines tyrosine kinase inhibitors multidrug-resistant human cells multidrug-resistance protein abcg2 cancer stem cells stem cell resistance cancer stem cell atp-binding cassette atp binding cassette mammary gland biology estrogen receptor protecting stem cells tumour stem cells hematopoietic stem cells germinal stem cells michael dean everts-van der wind adult heart atp-binding proteins side population cells �side population’ cells mouse blood-brain barrier abc transporter bcrp1/abcg2 abc transport genes multidrug resistance transporter therapeutic targets stem cells assist cancer cells estrogen response element full article pdf atp-dependent transporters bacterial transport proteins article dean reverses multidrug resistance related subjects author correspondence side-population phenotype human tumor cells bovine mammary tissue transmembrane inhibitors plant abc transporters abcg2 multidrug transporter multifunctional efflux transporters breast cancer res privacy choices/manage cookies

Questions {❓}

  • PI3 kinase activation and response to Trastuzumab Therapy: what’s neu with herceptin resistance?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:ABC Transporters, Drug Resistance, and Cancer Stem Cells
         description:The protection of the body’s stem cells from damage or death due to toxins is a critical function of an organism, as the stem cells need to remain intact for the entire life of the organism. One of the principal mechanisms for protecting stem cells is through the expression of multifunctional efflux transporters from the ATP-binding cassette (ABC) gene family. These same transporters have been known for over 25 years to also play a role in multidrug resistance of tumor cells. An exciting outcome of the concept of the cancer stem cell is that the tumor initiating cell may be innately resistant to many standard therapies. This provides one mechanism in which cancer stem cells could survive cytotoxic or targeted therapies and lead to tumor regrowth or relapse. Gaining a better insight into the mechanisms of stem cell resistance to chemotherapy might therefore lead to new therapeutic targets and better anti-cancer strategies.
         datePublished:2009-02-18T00:00:00Z
         dateModified:2009-02-18T00:00:00Z
         pageStart:3
         pageEnd:9
         sameAs:https://doi.org/10.1007/s10911-009-9109-9
         keywords:
            ATP-binding cassette transporters
            Cancer stem cell
            Multidrug resistance
            Estrogen
            Aromatase
            EGF receptor
            Transport inhibitors
            Oncology
            Cancer Research
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            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10911-009-9109-9/MediaObjects/10911_2009_9109_Fig2_HTML.gif
         isPartOf:
            name:Journal of Mammary Gland Biology and Neoplasia
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               name:Michael Dean
               affiliation:
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                     address:
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      headline:ABC Transporters, Drug Resistance, and Cancer Stem Cells
      description:The protection of the body’s stem cells from damage or death due to toxins is a critical function of an organism, as the stem cells need to remain intact for the entire life of the organism. One of the principal mechanisms for protecting stem cells is through the expression of multifunctional efflux transporters from the ATP-binding cassette (ABC) gene family. These same transporters have been known for over 25 years to also play a role in multidrug resistance of tumor cells. An exciting outcome of the concept of the cancer stem cell is that the tumor initiating cell may be innately resistant to many standard therapies. This provides one mechanism in which cancer stem cells could survive cytotoxic or targeted therapies and lead to tumor regrowth or relapse. Gaining a better insight into the mechanisms of stem cell resistance to chemotherapy might therefore lead to new therapeutic targets and better anti-cancer strategies.
      datePublished:2009-02-18T00:00:00Z
      dateModified:2009-02-18T00:00:00Z
      pageStart:3
      pageEnd:9
      sameAs:https://doi.org/10.1007/s10911-009-9109-9
      keywords:
         ATP-binding cassette transporters
         Cancer stem cell
         Multidrug resistance
         Estrogen
         Aromatase
         EGF receptor
         Transport inhibitors
         Oncology
         Cancer Research
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            name:Michael Dean
            affiliation:
                  name:National Cancer Institute
                  address:
                     name:Laboratory of Experimental Immunology, Cancer and Inflammation Program, National Cancer Institute, Frederick, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
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      volumeNumber:14
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      name:Springer US
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Person:
      name:Michael Dean
      affiliation:
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               name:Laboratory of Experimental Immunology, Cancer and Inflammation Program, National Cancer Institute, Frederick, USA
               type:PostalAddress
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      name:Laboratory of Experimental Immunology, Cancer and Inflammation Program, National Cancer Institute, Frederick, USA
WebPageElement:
      isAccessibleForFree:
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External Links {🔗}(235)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Crossref

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