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Erratum to: Functional and molecular characterisation of mammary side population cells | Breast Cancer Research
Description:
It has been brought to our attention that there was an inaccuracy in the above article [1]. In the discussion section the authors state that "One of the assumptions underlying mammary transplant studies is that mammary outgrowths at limiting dilution are clonal (14,000–20,000 cells per cleared fat pad)" and they attribute this to reference 21 "Smith GH: Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat 1996, 39:21–31" [2]. In the paper by Smith no claim of clonality is made, rather it is stated that it is not known whether the simultaneous development of both lobular and ductal phenotypes indicates cooperative interaction between the two epithelial progenitors or signals the presence of a third progenitor type capable of producing both ductular and lobular committed daughters. It is, therefore, incorrect that the assumption of clonality based on limiting dilution has been attributed to Gilbert Smith.
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cancer, article, research, breast, mammary, privacy, cookies, molecular, cells, information, publish, search, download, alvi, clayton, joshi, smalley, smith, lobular, res, cell, institute, content, data, journal, erratum, functional, characterisation, side, population, published, december, enver, ashworth, vivanco, dale, matthew, section, epithelial, progenitors, ductal, discover, london, function, optional, personal, parties, policy, find, track,
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progenitor type capable breast cancer res cell privacy choices/manage cookies cancer research authors state article number e1 article alvi netherlands cancer institute european economic area cleared fat pad related subjects conditions privacy policy distinct cellular progenitors clonal accepting optional cookies lobular committed daughters mammary outgrowths journal finder publish tariq enver chirag joshi alan ashworth & maria uk azra original article 000 cells smith gh epithelial progenitors 1186/bcr547 rights article cite privacy policy personal data books a discussion section erratum smalley mj optional cookies manage preferences alvi vivanco section uk trevor data protection essential cookies cookies skip alan ashworth gilbert smith netherlands matthew journal publish article [1] usage analysis social media
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headline:Erratum to: Functional and molecular characterisation of mammary side population cells
description:It has been brought to our attention that there was an inaccuracy in the above article [1]. In the discussion section the authors state that "One of the assumptions underlying mammary transplant studies is that mammary outgrowths at limiting dilution are clonal (14,000–20,000 cells per cleared fat pad)" and they attribute this to reference 21 "Smith GH: Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat 1996, 39:21–31" [2]. In the paper by Smith no claim of clonality is made, rather it is stated that it is not known whether the simultaneous development of both lobular and ductal phenotypes indicates cooperative interaction between the two epithelial progenitors or signals the presence of a third progenitor type capable of producing both ductular and lobular committed daughters. It is, therefore, incorrect that the assumption of clonality based on limiting dilution has been attributed to Gilbert Smith.
datePublished:2002-12-04T00:00:00Z
dateModified:2002-12-04T00:00:00Z
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Cancer Research
Oncology
Surgical Oncology
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headline:Erratum to: Functional and molecular characterisation of mammary side population cells
description:It has been brought to our attention that there was an inaccuracy in the above article [1]. In the discussion section the authors state that "One of the assumptions underlying mammary transplant studies is that mammary outgrowths at limiting dilution are clonal (14,000–20,000 cells per cleared fat pad)" and they attribute this to reference 21 "Smith GH: Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat 1996, 39:21–31" [2]. In the paper by Smith no claim of clonality is made, rather it is stated that it is not known whether the simultaneous development of both lobular and ductal phenotypes indicates cooperative interaction between the two epithelial progenitors or signals the presence of a third progenitor type capable of producing both ductular and lobular committed daughters. It is, therefore, incorrect that the assumption of clonality based on limiting dilution has been attributed to Gilbert Smith.
datePublished:2002-12-04T00:00:00Z
dateModified:2002-12-04T00:00:00Z
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Oncology
Surgical Oncology
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