Here's how DOI.ORG makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://link.springer.com/article/10.1007/s00403-015-1546-2, but it redirected us to https://link.springer.com/article/10.1007/s00403-015-1546-2. The analysis below is for the second page.

Title[redir]:
The divergent roles of growth differentiation factor-15 (GDF-15) in benign and malignant skin pathologies | Archives of Dermatological Research
Description:
GDF-15 (Growth Differentiation Factor-15) is a member of the transforming growth factor β (TGF-β) superfamily. GDF-15 is not only involved in cancer development, progression, angiogenesis and metastasis, but also controls stress responses, bone formation, hematopoietic development, adipose tissue function and cardiovascular diseases. GDF-15, which is regulated by p53, has shown antitumorigenic and proapoptotic activities in vivo and in vitro. Also, GDF-15 is involved in skin biology and histamine-induced melanogenesis; it is overexpressed in melanoma cells and is associated with depth of tumor invasion and metastasis. GDF-15 level is increased in patients with systemic sclerosis and is related with the degree of skin sclerosis and intensity of pulmonary fibrosis. In the future, GDF-15 may be a potential target for therapy in benign disorders with skin fibrosis and malignant lesions of the skin.

Matching Content Categories {📚}

  • Education
  • Science
  • Health & Fitness

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,420 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Doi.org Make Money? {💸}

We can't figure out the monetization strategy.

Many websites are intended to earn money, but some serve to share ideas or build connections. Websites exist for all kinds of purposes. This might be one of them. Doi.org might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

pubmed, google, scholar, article, cas, cancer, growth, res, melanoma, factor, cytokine, inhibitory, gdf, macrophage, lee, cells, cell, breit, kim, dermatol, biol, expression, differentiation, skin, tgfbeta, brown, transforming, fibrosis, central, malignant, development, bone, mic, human, clin, bauskin, research, superfamily, patients, systemic, sclerosis, gene, arch, privacy, cookies, content, member, access, lung, chem,

Topics {✒️}

growth/differentiation factor-15/macrophage-inhibiting cytokine-1 month download article/chapter anti-senescence factor tbx2 tgf-beta2 inhibits growth growth differentiation factor-15 tgf-beta1 polymorphism determines tgf-beta superfamily cytokine nested case-control study bleomycin-induced pulmonary fibrosis cellular signalling network tgf-beta superfamily member cumhur i̇brahim başsorgun growth inhibitory effect ayşe akman karakaş uv-induced skin damage macrophage inhibitory cytokine-1 macrophage inhibitory cytokine tgf-beta superfamily full article pdf histamine-induced melanogenesis uv-mediated regulation tgf-beta signaling tgf-beta pathway nsaid activated gene human dermal fibroblasts tyrosinase-related protein-1 privacy choices/manage cookies bone morphogenetic proteins paralkar vm systemic protumorigenic effects dermatology author correspondence transient gene transfer gene expression contribute bone morphogenic proteins dermatological research aims propeptide mediates formation systemic sclerosis normal human melanocytes central regulator mic-1 serum level retinoid-related molecules check access instant access fibroblast-derived gdf15 tgf-β cutaneous melanoma incidence baek sj glioblastoma cells independently article ünal

Questions {❓}

  • Sherr CJ, DePinho RA (2000) Cellular senescence: mitotic clock or culture shock?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:The divergent roles of growth differentiation factor-15 (GDF-15) in benign and malignant skin pathologies
         description:GDF-15 (Growth Differentiation Factor-15) is a member of the transforming growth factor β (TGF-β) superfamily. GDF-15 is not only involved in cancer development, progression, angiogenesis and metastasis, but also controls stress responses, bone formation, hematopoietic development, adipose tissue function and cardiovascular diseases. GDF-15, which is regulated by p53, has shown antitumorigenic and proapoptotic activities in vivo and in vitro. Also, GDF-15 is involved in skin biology and histamine-induced melanogenesis; it is overexpressed in melanoma cells and is associated with depth of tumor invasion and metastasis. GDF-15 level is increased in patients with systemic sclerosis and is related with the degree of skin sclerosis and intensity of pulmonary fibrosis. In the future, GDF-15 may be a potential target for therapy in benign disorders with skin fibrosis and malignant lesions of the skin.
         datePublished:2015-02-18T00:00:00Z
         dateModified:2015-02-18T00:00:00Z
         pageStart:551
         pageEnd:557
         sameAs:https://doi.org/10.1007/s00403-015-1546-2
         keywords:
            Growth Differentiation Factor-15
            GDF-15
            MIC-1
            Systemic sclerosis
            Melanoma
            Senescence
            Dermatology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig3_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig4_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig5_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig6_HTML.gif
         isPartOf:
            name:Archives of Dermatological Research
            issn:
               1432-069X
               0340-3696
            volumeNumber:307
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer Berlin Heidelberg
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Betül Ünal
               affiliation:
                     name:Akdeniz University
                     address:
                        name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Sevil Alan
               affiliation:
                     name:Akdeniz University
                     address:
                        name:Department of Dermatology and Venerology, School of Medicine, Akdeniz University, Antalya, Turkey
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Cumhur İbrahim Başsorgun
               affiliation:
                     name:Akdeniz University
                     address:
                        name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ayşe Akman Karakaş
               affiliation:
                     name:Akdeniz University
                     address:
                        name:Department of Dermatology and Venerology, School of Medicine, Akdeniz University, Antalya, Turkey
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Gülsüm Özlem Elpek
               affiliation:
                     name:Akdeniz University
                     address:
                        name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mehmet Akif Çiftçioğlu
               affiliation:
                     name:Akdeniz University
                     address:
                        name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:The divergent roles of growth differentiation factor-15 (GDF-15) in benign and malignant skin pathologies
      description:GDF-15 (Growth Differentiation Factor-15) is a member of the transforming growth factor β (TGF-β) superfamily. GDF-15 is not only involved in cancer development, progression, angiogenesis and metastasis, but also controls stress responses, bone formation, hematopoietic development, adipose tissue function and cardiovascular diseases. GDF-15, which is regulated by p53, has shown antitumorigenic and proapoptotic activities in vivo and in vitro. Also, GDF-15 is involved in skin biology and histamine-induced melanogenesis; it is overexpressed in melanoma cells and is associated with depth of tumor invasion and metastasis. GDF-15 level is increased in patients with systemic sclerosis and is related with the degree of skin sclerosis and intensity of pulmonary fibrosis. In the future, GDF-15 may be a potential target for therapy in benign disorders with skin fibrosis and malignant lesions of the skin.
      datePublished:2015-02-18T00:00:00Z
      dateModified:2015-02-18T00:00:00Z
      pageStart:551
      pageEnd:557
      sameAs:https://doi.org/10.1007/s00403-015-1546-2
      keywords:
         Growth Differentiation Factor-15
         GDF-15
         MIC-1
         Systemic sclerosis
         Melanoma
         Senescence
         Dermatology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig3_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig4_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig5_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00403-015-1546-2/MediaObjects/403_2015_1546_Fig6_HTML.gif
      isPartOf:
         name:Archives of Dermatological Research
         issn:
            1432-069X
            0340-3696
         volumeNumber:307
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer Berlin Heidelberg
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Betül Ünal
            affiliation:
                  name:Akdeniz University
                  address:
                     name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Sevil Alan
            affiliation:
                  name:Akdeniz University
                  address:
                     name:Department of Dermatology and Venerology, School of Medicine, Akdeniz University, Antalya, Turkey
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Cumhur İbrahim Başsorgun
            affiliation:
                  name:Akdeniz University
                  address:
                     name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ayşe Akman Karakaş
            affiliation:
                  name:Akdeniz University
                  address:
                     name:Department of Dermatology and Venerology, School of Medicine, Akdeniz University, Antalya, Turkey
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Gülsüm Özlem Elpek
            affiliation:
                  name:Akdeniz University
                  address:
                     name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mehmet Akif Çiftçioğlu
            affiliation:
                  name:Akdeniz University
                  address:
                     name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Archives of Dermatological Research
      issn:
         1432-069X
         0340-3696
      volumeNumber:307
Organization:
      name:Springer Berlin Heidelberg
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Akdeniz University
      address:
         name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
         type:PostalAddress
      name:Akdeniz University
      address:
         name:Department of Dermatology and Venerology, School of Medicine, Akdeniz University, Antalya, Turkey
         type:PostalAddress
      name:Akdeniz University
      address:
         name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
         type:PostalAddress
      name:Akdeniz University
      address:
         name:Department of Dermatology and Venerology, School of Medicine, Akdeniz University, Antalya, Turkey
         type:PostalAddress
      name:Akdeniz University
      address:
         name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
         type:PostalAddress
      name:Akdeniz University
      address:
         name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Betül Ünal
      affiliation:
            name:Akdeniz University
            address:
               name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Sevil Alan
      affiliation:
            name:Akdeniz University
            address:
               name:Department of Dermatology and Venerology, School of Medicine, Akdeniz University, Antalya, Turkey
               type:PostalAddress
            type:Organization
      name:Cumhur İbrahim Başsorgun
      affiliation:
            name:Akdeniz University
            address:
               name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
               type:PostalAddress
            type:Organization
      name:Ayşe Akman Karakaş
      affiliation:
            name:Akdeniz University
            address:
               name:Department of Dermatology and Venerology, School of Medicine, Akdeniz University, Antalya, Turkey
               type:PostalAddress
            type:Organization
      name:Gülsüm Özlem Elpek
      affiliation:
            name:Akdeniz University
            address:
               name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
               type:PostalAddress
            type:Organization
      name:Mehmet Akif Çiftçioğlu
      affiliation:
            name:Akdeniz University
            address:
               name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
      name:Department of Dermatology and Venerology, School of Medicine, Akdeniz University, Antalya, Turkey
      name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
      name:Department of Dermatology and Venerology, School of Medicine, Akdeniz University, Antalya, Turkey
      name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
      name:Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(307)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Hammer.js
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Crossref

4.72s.