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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Schema
  9. External Links
  10. Analytics And Tracking
  11. Libraries
  12. Hosting Providers
  13. CDN Services

We began analyzing https://link.springer.com/article/10.1007/s00280-004-0890-2, but it redirected us to https://link.springer.com/article/10.1007/s00280-004-0890-2. The analysis below is for the second page.

Title[redir]:
Molecular targeting therapy for pancreatic cancer | Cancer Chemotherapy and Pharmacology
Description:
Pancreatic carcinogenesis is driven by multiple genetic and epigenetic changes. The epidermal growth factor receptor (EGFR) and its downstream signaling pathways, Ras-Raf-MEK-ERK axis, play important roles in pancreatic cancer development. The phosphoinositol 3 kinase (PI3 K)/Akt and the nuclear factor κB (NF-κB) pathways control both proliferation and resistance to apoptosis of pancreatic cancer. The role of cyclooxygenase (COX) and lipoxygenase (LOX) in the development of pancreatic cancer has been made known recently. The elucidation of these molecular events has led to several distinct therapeutic advances, including therapies that target EGFR, the Ras-Raf-MEK-ERK axis, the COX-2 and LOX pathways, and others. Many novel agents have been developed and are undergoing clinical investigation, such as monoclonal antibodies against EGFR, tyrosine kinase inhibitors (TKIs), farnesyl transferase inhibitors (FTIs), Bay43-9006, CI-1040, CCI-779, celecoxib, and LY293111. This review highlights recent advances in the development of these agents.

Matching Content Categories {📚}

  • Education
  • Science
  • Health & Fitness

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Doi.org Make Money? {💸}

We don't see any clear sign of profit-making.

While many websites aim to make money, others are created to share knowledge or showcase creativity. People build websites for various reasons. This could be one of them. Doi.org might be plotting its profit, but the way they're doing it isn't detectable yet.

Keywords {🔍}

cancer, google, scholar, pancreatic, pubmed, cas, human, article, clin, res, growth, oncol, abstract, factor, proc, receptor, soc, phase, cells, study, gemcitabine, cell, abbruzzese, antibody, patients, advanced, inhibitor, epidermal, apoptosis, inhibitors, xiong, kinase, cyclooxygenase, tumor, proliferation, combination, adrian, carcinoma, therapy, egfr, signaling, lipoxygenase, ding, molecular, nuclear, inhibition, pathway, mice, wang, yang,

Topics {✒️}

mutant c-k-ras genes ras-raf-mek-erk axis rel/nf-κb/iκb proteins month download article/chapter g1-arresting rapamycin-receptor complex molecular targeting therapy nonsteroidal anti-inflammatory drugs combinatorial ligand-receptor interactions mammalian protein targeted leukotriene b4 receptor farnesyl transferase inhibitors advanced nonsmall-cell lung gemcitabine-induced cell death anti-egfr antibody epidermal growth factor ltb4 receptor antagonist phosphoinositide 3-kinase pathway human pancreatic adenocarcinoma tyrosine kinase inhibitors fully human antibodies article cancer chemotherapy human pancreatic carcinoma full article pdf cyclooxygenase-2 inhibits proliferation human pancreatic cancer metastatic pancreatic adenocarcinoma distinct therapeutic advances including therapies g1 arrest mediated pancreatic cancer xenografts slows tumor growth privacy choices/manage cookies human pancreatic cancers human pancreatic adenocarcinomas pancreatic carcinoma cells nuclear factor κb oral mek inhibitor kirsten-ras oncogene nuclear factor kappab nuclear factor-kappab human pancreatic carcinomas pancreatic cancer cells nuclear factor-kappa advanced pancreatic cancer tyrosine kinase activity mek/erk activation van de velde pancreatic cancer published rela transcription factor enhanced tumor aggressiveness

Schema {🗺️}

WebPage:
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         headline:Molecular targeting therapy for pancreatic cancer
         description:Pancreatic carcinogenesis is driven by multiple genetic and epigenetic changes. The epidermal growth factor receptor (EGFR) and its downstream signaling pathways, Ras-Raf-MEK-ERK axis, play important roles in pancreatic cancer development. The phosphoinositol 3 kinase (PI3 K)/Akt and the nuclear factor κB (NF-κB) pathways control both proliferation and resistance to apoptosis of pancreatic cancer. The role of cyclooxygenase (COX) and lipoxygenase (LOX) in the development of pancreatic cancer has been made known recently. The elucidation of these molecular events has led to several distinct therapeutic advances, including therapies that target EGFR, the Ras-Raf-MEK-ERK axis, the COX-2 and LOX pathways, and others. Many novel agents have been developed and are undergoing clinical investigation, such as monoclonal antibodies against EGFR, tyrosine kinase inhibitors (TKIs), farnesyl transferase inhibitors (FTIs), Bay43-9006, CI-1040, CCI-779, celecoxib, and LY293111. This review highlights recent advances in the development of these agents.
         datePublished:2004-08-13T00:00:00Z
         dateModified:2004-08-13T00:00:00Z
         pageStart:S69
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            Molecular targeting therapy
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            Pharmacology/Toxicology
            Cancer Research
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      headline:Molecular targeting therapy for pancreatic cancer
      description:Pancreatic carcinogenesis is driven by multiple genetic and epigenetic changes. The epidermal growth factor receptor (EGFR) and its downstream signaling pathways, Ras-Raf-MEK-ERK axis, play important roles in pancreatic cancer development. The phosphoinositol 3 kinase (PI3 K)/Akt and the nuclear factor κB (NF-κB) pathways control both proliferation and resistance to apoptosis of pancreatic cancer. The role of cyclooxygenase (COX) and lipoxygenase (LOX) in the development of pancreatic cancer has been made known recently. The elucidation of these molecular events has led to several distinct therapeutic advances, including therapies that target EGFR, the Ras-Raf-MEK-ERK axis, the COX-2 and LOX pathways, and others. Many novel agents have been developed and are undergoing clinical investigation, such as monoclonal antibodies against EGFR, tyrosine kinase inhibitors (TKIs), farnesyl transferase inhibitors (FTIs), Bay43-9006, CI-1040, CCI-779, celecoxib, and LY293111. This review highlights recent advances in the development of these agents.
      datePublished:2004-08-13T00:00:00Z
      dateModified:2004-08-13T00:00:00Z
      pageStart:S69
      pageEnd:S77
      sameAs:https://doi.org/10.1007/s00280-004-0890-2
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            name:University of Texas MD Anderson Cancer Center
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               name:Department of Gastrointestinal Medical Oncology, Unit 426, University of Texas MD Anderson Cancer Center, Houston, USA
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External Links {🔗}(221)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
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Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
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Name Servers:

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CDN Services {📦}

  • Crossref

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