
DOI . ORG {
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Title[redir]:
TOR: The First 10 Years | SpringerLink
Description:
TOR was discovered and christened 10 years ago. On the occasion of this anniversary, we revisit the discovery of TOR and chronicle subsequent breakthroughs in S. cerevisiae that contributed to an understanding of TOR function in yeast and higher eukaryotes. In...
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Keywords {π}
google, scholar, pubmed, cas, article, tor, cell, hall, biol, yeast, rapamycin, kinase, protein, mol, target, chapter, signaling, schreiber, growth, translation, pathway, chem, sci, usa, cerevisiae, heitman, mammalian, dev, proc, natl, acad, control, saccharomyces, genes, schmidt, curr, response, helliwell, transcription, complex, privacy, cookies, content, information, publish, access, download, regulates, domain, factors,
Topics {βοΈ}
g1-arresting rapamycin-receptor complex month download article/chapter branched-chain amino acids 11-kda fkbp12-rapamycin-binding domain di como cj affiliations friedrich-miescher-institute tap42-sit4-rrd1/2 pathway rapamycin-modulated transcription defines p70 s6 kinase amino acid availability fkbp12-rapamycin complex interacting nitrogen-quality signaling nutrient-sensitive complex tor signaling pathway rapamycin-sensitive tor function amino acid sufficiency phosphatidylinositol kinase homologue type 2a phosphatases cell integrity pathway privacy choices/manage cookies mammalian phosphatidylinositol 3-kinase akt/mtor pathway rhol effector pkcl brown ej crespo jl device instant download ribosomal protein s6 akt/protein kinase exchange factor rom2 rtg3 transcription factors tor kinase homologs tor kinase domains protein kinase activity rapamycin- dependent fashion pik-related kinases multiple translation factors 289-kda fkbp12-rapamycin fkbp12/rapamycin complex fkbp12-rapamycin complex download preview pdf european economic area chronicle subsequent breakthroughs toxic effector domain gingras ac nonnatural immunophilin ligand isolated rat hepatocytes skeletal muscle hypertrophy dominant missense mutations zheng xf kuruvilla fg
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ScholarlyArticle:
headline:TOR: The First 10 Years
pageEnd:18
pageStart:1
image:https://media.springernature.com/w153/springer-static/cover/book/978-3-642-18930-2.jpg
genre:
Biomedical and Life Sciences
Biomedical and Life Sciences (R0)
isPartOf:
name:TOR
isbn:
978-3-642-18930-2
978-3-642-62360-8
type:Book
publisher:
name:Springer Berlin Heidelberg
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url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:A. Lorberg
affiliation:
name:University of Basel
address:
name:Division of Biochemistry, Biozentrum, University of Basel, Basel, Switzerland
type:PostalAddress
type:Organization
type:Person
name:M. N. Hall
affiliation:
name:University of Basel
address:
name:Division of Biochemistry, Biozentrum, University of Basel, Basel, Switzerland
type:PostalAddress
type:Organization
type:Person
keywords:Actin Cytoskeleton, Rapamycin Treatment, Heat Repeat, Vacuolar Target, FATC Domain
description:TOR was discovered and christened 10 years ago. On the occasion of this anniversary, we revisit the discovery of TOR and chronicle subsequent breakthroughs in S. cerevisiae that contributed to an understanding of TOR function in yeast and higher eukaryotes. In particular, we discuss findings that led to the realization that the function of TOR is to control cell growth in response to nutrients.
datePublished:2004
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