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cvcl_0045 hek-blue ifn-α/β reporter-cell-line-based neutralization assay sle lacking neutralizing-anti-ifn-abs anti-ifn-abs remains unknown 105 ifn-α-hek-blue cells anti-ifn-ab-negative patients showed neutralizing anti-ifn-abs halted neutralizing anti-ifn-abs remains neutralizing anti-ifn-abs mirrored neutralizing anti-ifn-abs reduced neutralizing anti-ifn-abs increased anti-ifn-α-autoantibody levels sle lacking anti-ifn-abs endogenous anti-interferon-α autoantibodies rnase-free dnase set high anti-ifn-ab levels neutralizing anti-ifn-abs compared low anti-ifn-ab titers neutralizing anti-ifn-ab patients anti-ifn-ab-negative patients 9 anti-ifn-ab-negative patients cytokine-anti-cytokine antibody complexes anti-ifn-abs mirrored neutralizing anti-ifn-ab anti-ifn-abs display anti-ifn-ab negative anti-ifn-ab-negative neutralizing-anti-ifn-abs neutralizing anti-ifn-abs neutralizing anti-ifn-abs neutralizing anti-ifn-abs anti-ifn-i-abs anti-ifn-ab production displayed anti-ifn-abs anti-ifn-ab titers anti-ifn-abs represented graphical abstract hu-pbl-scid mice anti-double-stranded dna interferon-α-induced genes pmc beta search ab_389310 cd4 pe/dazzle595 100 iu/mg penicillin/streptomycin urea/electrolytes/serum creatinine ab_2563630 icos pe/cy7 anti-ifnα-autoab-negative supplemental information mmc2 cross-sectional abnon-neut relapsing-remitting multiple sclerosis colorimetric enzyme assay

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