
NCBI . NLM . NIH . GOV {
}
Title[redir]:
How mRNA and nascent chain sequences regulate translation elongation - PMC
Description:
Translation elongation is a highly coordinated, multistep, multi-factor process that ensures accurate and efficient addition of amino acids to a growing nascent-peptide encoded in the sequence of translated mRNA. While translation elongation is ...
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Keywords {🔍}
doi, pubmed, google, scholar, translation, mrna, pmc, free, article, ribosome, elongation, translocation, frameshifting, ribosomal, trna, decoding, protein, cell, sequence, site, nascent, peptide, methods, codon, dynamics, rna, translational, structure, mol, structural, biol, structures, elements, nascentpeptide, kinetics, nat, recoding, codons, sci, mechanism, multiple, factor, stalling, figure, synthesis, dynamic, modifications, gene, complex, interaction,
Topics {✒️}
ef-tu•gdp•aa-trna rejection pathway lysine-encoding a-rich sequences ef-tu•gdp dissociation pathway ef-tu•gdp•aa-trna single-molecule fluorescence microscopy single-particle cryo-em cs-corrected cryo-em ef-tu•gdp dissociation nascent chain-induced stalling codon-anticodon helix favors multi-step chemical reactions pmc beta search scattered x-rays generated solid-state nmr enhanced cryogenic electron microscopy nonpolypeptide prolyl-trna functions cell-type-specific translational landscape time-resolved cryo-em nascent-peptide exit tunnel macrolide-induced ribosomal frameshifting drug-obstructed exit tunnel nascent-peptide elements manipulate nascent-peptide elements perturb coli ribosome–ef-tu complex limited experimental time-points form codon-anticodon helix preventing peptide-bond formation ensemble cryo-em elucidates real-time trna transit ef-g-accelerated rotation nearby strong sd-sequence ermbl-mediated translation arrest spring-loaded base modification codon-anticodon helix leads preventing codon-anticodon interactions single-molecule structural dynamics successful peptide-bond formation secm-induced translational stalling aminoacyl-acceptor trna site codon-anticodon interaction distorts broken codon-anticodon interaction ultrahigh-resolution optical trap proximity-specific ribosome profiling a-site aminoacyl-trna requiring real-time measurements a-site peptidyl acceptor nascent-peptide elements affect dynamic n1-methyladenosine methylome secm-mediated ribosomal stall growing nascent-peptide encoded
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- Grand Challenge Commentary: RNA epigenetics?
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- Earnings of https://doi.org/10.1016/j.cell.2014.08.011
- Monthly income for https://scholar.google.com/scholar_lookup?journal=Cell&title=A%20Dual%20Program%20for%20Translation%20Regulation%20in%20Cellular%20Proliferation%20and%20Differentiation.&author=H%20Gingold&author=D%20Tehler&author=NR%20Christoffersen&author=MM%20Nielsen&author=F%20Asmar&volume=158&issue=6&publication_year=2014&pages=1281-92&pmid=25215487&doi=10.1016/j.cell.2014.08.011&
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- Check the income stats for https://scholar.google.com/scholar_lookup?journal=Cell&title=Modulated%20expression%20of%20specific%20tRNAs%20drives%20gene%20expression%20and%20cancer%20progression.&author=H%20Goodarzi&author=HCB%20Nguyen&author=S%20Zhang&author=BD%20Dill&author=H%20Molina&volume=165&issue=6&publication_year=2016&pages=1416-27&pmid=27259150&doi=10.1016/j.cell.2016.05.046&
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- Monthly income for https://scholar.google.com/scholar_lookup?journal=Nat.%20Rev.%20Genet&title=Emerging%20roles%20of%20tRNA%20in%20adaptive%20translation,%20signalling%20dynamics%20and%20disease.&author=S%20Kirchner&author=Z%20Ignatova&volume=16&issue=2&publication_year=2014&pages=98-112&pmid=25534324&doi=10.1038/nrg3861&
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- How profitable is https://doi.org/10.1016/j.cell.2016.05.070?
- How much does https://scholar.google.com/scholar_lookup?journal=Cell&title=Adjacent%20Codons%20Act%20in%20Concert%20to%20Modulate%20Translation%20Efficiency%20in%20Yeast.&author=CE%20Gamble&author=CE%20Brule&author=KM%20Dean&author=S%20Fields&author=EJ%20Grayhack&volume=166&issue=3&publication_year=2016&pages=679-90&pmid=27374328&doi=10.1016/j.cell.2016.05.070& pull in?
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- What's the total monthly financial gain of https://doi.org/10.1038/srep21139?
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Sci.%20Rep&title=High%20frequency%20of%20+1%20programmed%20ribosomal%20frameshifting%20in%20Euplotes%20octocarinatus.&author=R%20Wang&author=J%20Xiong&author=W%20Wang&author=W%20Miao&author=A%20Liang&volume=6&issue=February&publication_year=2016&pages=21139&pmid=26891713&doi=10.1038/srep21139& bring in?
- What's the financial outcome of https://doi.org/10.1126/science.2830666?
- What's the financial intake of https://scholar.google.com/scholar_lookup?journal=Science&title=A%20Persistent%20Untranslated%20Sequence%20Within%20Bacteriophage%20T4%20DNA%20Topoisomerase%20Gene%2060.&author=WM%20Huang&author=S%20Ao&author=S%20Casjens&author=R%20Orlandi&author=R%20Zeikus&volume=239&issue=4843&publication_year=1988&pages=1005-12&pmid=2830666&doi=10.1126/science.2830666&?
- How much does https://doi.org/10.1016/j.cell.2015.10.064 bring in each month?
- How much does https://scholar.google.com/scholar_lookup?journal=Cell&title=Coupling%20of%20mRNA%20Structure%20Rearrangement%20to%20Ribosome%20Movement%20during%20Bypassing%20of%20Non-coding%20Regions.&author=J%20Chen&author=A%20Coakley&author=M%20O%E2%80%99Connor&author=A%20Petrov&author=SE%20O%E2%80%99Leary&volume=163&issue=5&publication_year=2015&pages=1267-80&pmid=26590426&doi=10.1016/j.cell.2015.10.064& earn?
- What's the income generated by https://doi.org/10.1126/sciadv.1700147 each month?
- What's the monthly money flow for https://scholar.google.com/scholar_lookup?journal=Sci.%20Adv&title=Ribosome%20rearrangements%20at%20the%20onset%20of%20translational%20bypassing.&author=X%20Agirrezabala&author=E%20Samatova&author=M%20Klimova&author=M%20Zamora&author=D%20Gil-carton&volume=3&publication_year=2017&pages=e1700147&pmid=28630923&doi=10.1126/sciadv.1700147&?
- Check the income stats for https://doi.org/10.1038/ncomms5459
- What's the revenue for https://scholar.google.com/scholar_lookup?journal=Nat.%20Commun&title=High-efficiency%20translational%20bypassing%20of%20non-coding%20nucleotides%20specified%20by%20mRNA%20structure%20and%20nascent%20peptide.&author=E%20Samatova&author=AL%20Konevega&author=NM%20Wills&author=JF%20Atkins&author=MV%20Rodnina&volume=5&publication_year=2014&pages=4459&pmid=25041899&doi=10.1038/ncomms5459&?
- How much revenue does https://github.com/ncbi bring in?
- How much does https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/%4038.9959508, -77.101021,17z/data%3D!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb%3A0x19156f88b27635b8!8m2!3d38.9959508! 4d-77.0988323 pull in?
- How much income is https://www.nlm.nih.gov/web_policies.html earning monthly?
- https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office's total income per month
- What is the monthly revenue of https://www.hhs.gov/vulnerability-disclosure-policy/index.html?
- What is the monthly revenue of https://support.nlm.nih.gov/?pagename=cloudpmc-viewer%3Apmc%3Aarticle%3Amanuscript?
- https://www.nlm.nih.gov/accessibility.html's total income per month
- How much does https://www.nlm.nih.gov/careers/careers.html pull in monthly?
- Revenue of https://www.nlm.nih.gov/
- Monthly income for https://www.nih.gov/
- What's the financial outcome of https://www.hhs.gov/?
- How much cash flow does https://www.usa.gov/ have monthly?
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