
NCBI . NLM . NIH . GOV {
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Title[redir]:
Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling - PMC
Description:
Objective: Cancer stem cells (CSCs) are responsible for the drug resistance of breast cancers. Vitamin D deficiency promotes tumor resistance. The present study examined the effect of vitamin D and vitamin D receptor (VDR) expression on the ...
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Keywords {🔍}
cells, vdr, cell, mcf, stem, expression, cancer, vitamin, tamoxifen, signaling, cscs, doi, wntβcatenin, breast, google, scholar, pubmed, resistance, pmc, ohd, apoptosis, article, figure, free, results, metastasis, higher, found, administration, treated, wnt, βcatenin, pathway, usa, sensitivity, overexpression, performed, proliferation, protein, tumor, methods, compared, csc, treatment, incubated, analysis, assay, receptor, viability, transfected,
Topics {✒️}
serum-free dmem/f-12 medium becton dickinson inactivate wnt/β-catenin signaling suppressing wnt/β-catenin signaling autocrine wnt/β-catenin signaling serum-free dmem/f-12 wnt/β-catenin signaling pathway wnt/β-catenin signaling factors common factor found inhibiting wnt/β-catenin signaling inhibits emt progression igg-fitc fluorescent antibody fitc-conjugated cd133 antibodies mesenchymal transition β-catenin/tcf-4 axis β-catenin signaling pathway fitc-conjugated cd133 antibody wnt/β-catenin signaling wnt/β-catenin signaling [30 fluorescence-activated cell sorting inhibit tumor growth fluorescence-activated cell sorter wnt/beta-catenin pathway ecl system vd/vdr signaling pathway targeting wnt/î²-catenin author contribution β-catenin binding member 2× dmem medium pmc beta search enhanced vdr expression trial sequential meta-analysis intestinal epithelial vitamin β-catenin protein expression promoting vdr-mediated p21 egf 25d ligand-activated vdr mesenchymal states reflective wnt signaling pathway g0/g1 phase mesenchymal multipotent cells β-catenin proteins competing interests limited-access data set vdr-mediated tamoxifen sensitivity hunan provincial health publisher site pdf β-catenin crossregulation vdr overexpression-induced inactivation β-catenin binding [28
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- (2015) The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?
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