
NCBI . NLM . NIH . GOV {
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Title[redir]:
Cirsiliol Suppressed Epithelial to Mesenchymal Transition in B16F10 Malignant Melanoma Cells through Alteration of the PI3K/Akt/NF-κB Signaling Pathway - PMC
Description:
Malignant melanoma is a highly aggressive form of skin cancer which has a propensity for metastasis. Epithelial mesenchymal transition (EMT) plays a primordial role in the progression of metastatic disease. Metastatic melanoma is resistant to ...
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Keywords {🔍}
cells, doi, cirsiliol, cell, emt, google, scholar, pubmed, expression, melanoma, figure, fninduced, ecadherin, cancer, snail, treated, pathway, pmc, mmp, twist, treatment, nfκb, fncir, article, pikakt, free, seeded, cellular, signaling, ncadherin, transition, metastatic, results, epithelial, assay, μgml, transcription, precoated, petri, dishes, control, nuclear, downregulation, akt, induction, effect, band, usa, mesenchymal, role,
Topics {✒️}
suppressing pi3k/akt/nf-κb pathway zeb2-mitf-zeb1 transcriptional network transforming growth factor-b1 pi3k/akt/nf-κb pathway fn-activated pi3k/akt phosphorylation transcription factor nf-kappa 2-5-diphenyl-2h-tetrazolium bromide multi-wall microplate reader [pubmed] [google scholar] nf-κbp65-mediated pathway [27 pi3k/akt/mammalian target inhibited tgf-β-induced emt nf-κb pathway upstream tgf-β signaling axes multi-targeted anticancer properties possess numerous health-promoting negative-feedback loop forms propidium iodide-dna complex dunnett t-test treats egfr/pi3k/akt pathway akt/pkb-mediated phosphorylation pi3k/akt signaling pathway nuclear nf-κb p65 pmc beta search pi3k/akt signalling pathway nf-κb p65 subunit fn-stimulated b16f10 cells pi3k/akt signalling pathways mtt-formazan product dissolved ras/raf/mek/erk embryonic emt-inducers drives bind e-box promoter pi3k/akt-mediated metastasis nf-κb transcriptional activity ethylenediaminetetraacetic acid-free /nuclear factor-κb [20 µg/ml]-induced cells fn-induced b16f10 cells fn+-induced b16f10 cells pi3k/akt signaling plays emt-inducing transcription factors cells expressing e-cadherin fn-induced melanoma cells pi3k/akt pathway cirsiliol basal epidermal layer time-dependent cytotoxic effect suppressing transcription factors sodium dodecyl sulfate fn-induced cells treated primary signaling pathways
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