
NCBI . NLM . NIH . GOV {
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Title[redir]:
SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of poor response to endocrine therapy in estrogen receptor-positive metastatic breast cancer - PMC
Description:
Endocrine resistance in estrogen receptor-positive (ER+) breast cancer is a major clinical problem and is associated with accelerated cancer cell growth, increased motility and acquisition of mesenchymal characteristics. However, the specific ...
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Keywords {🔍}
snai, cells, cancer, breast, cell, expression, doi, fulvestrantresistant, endocrine, growth, emt, pubmed, resistance, patients, google, scholar, therapy, lines, cohort, metastatic, data, levels, fulvestrant, gene, knockdown, sox, article, treatment, treated, fig, pmc, high, analysis, transcription, shown, pfs, estrogen, evaluated, tamoxifenresistant, protein, advanced, mesenchymal, receptor, phenotype, tamoxifen, compared, tumor, ecadherin, clinical, transition,
Topics {✒️}
false discovery rate formalin-fixed paraffin-embedded fulvestrant-resistant optical density horseradish peroxidase odense university hospital invade extracellular matrix paraffin-embedded ecm hrp-conjugated goat anti-rabbit hrp-conjugated donkey anti-goat adjusted hazard ratio estrogen receptor-positive breast cscs hazard ratio epithelial-mesenchymal transition mesenchymal-epithelial transition shorter progression-free survival hrp-conjugated powervision+™ system specific matrix effectors cscs growth rate progression-free survival ffpe fulvestrant-resistant met fdr od ouh fulvr fusion-fx7–7026 wl/26mx instrument emt-inducing transcription factor serum-free medium shorter relapse-free survival matrix biol estrogen receptor alpha estrogen receptor-alpha powervision poly-hrp 10% fbs medium phenol red-free dulbecco 4% formalin mesenchymal transition cancer stem cells ffpe sections low serum concentration triple-negative breast cancer fbs reverse transcription hr hr 2 hr 1 tamoxifen-resistant breast cancer
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