NCBI . NLM . NIH . GOV {
}
We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC5810112/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC5810112/. The analysis below is for the second page.
Title[redir]:
SF3B1 deficiency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS - PMC
Description:
SF3B1 is a core component of splicing machinery. Mutations in SF3B1 are frequently found in myelodysplastic syndromes (MDS), particularly in patients with refractory anemia with ringed sideroblasts (RARS), characterized by isolated anemia. SF3B1 ...
Title[redir]:
SF3B1 deficiency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS - PMC
Description:
SF3B1 is a core component of splicing machinery. Mutations in SF3B1 are frequently found in myelodysplastic syndromes (MDS), particularly in patients with refractory anemia with ringed sideroblasts (RARS), characterized by isolated anemia. SF3B1 ...
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What is the average monthly size of ncbi.nlm.nih.gov audience?
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Keywords {🔍}
sfb, doi, cells, knockdown, erythroid, pubmed, google, scholar, erythropoiesis, cell, analysis, expression, splicing, erythroblasts, pmc, article, fig, free, human, blood, mkrn, genes, apoptosis, anemia, differentiation, alternative, data, protein, additional, gene, file, cfue, growth, activation, cycle, findings, differentially, pathway, rnaseq, increased, shown, mutations, levels, email, effects, performed, day, xlsx, site, orthochromatic,
Topics {✒️}
colony-forming-unit-erythroid burst-forming-unit-erythroid cfu burst-forming-unit-erythroid myc-driven b-cell lymphomas human full-length mkrn1 epo/epor system multiple exon skipping/inclusion pgc-1alpha-responsive genes involved performed colony-forming assays murine erythropoietin receptor real-time quantitative rt-pcr exon skipping/inclusion pin1-induced proline isomerization colony-forming ability supplementary information files sf3b1-shrna2/pgfp-mkrn1 effects colony forming assay intron skipping/inclusion tissue-specific alternative splicing pmc beta search rabbit anti-mkrn1 antibody real-time rt-pcr pre-ranked list analysis fluorescence-activated cell sorting monoclonal anti-actin antibody pmc copyright notice sf3b1-shrna2/pgfp-mkrn1 pgk-ires-gfp plasmid luciferase-shrna proliferated exponentially human erythropoietin gene erythropoietin receptor post-transcriptional regulatory mechanism real-time pcr analysis stage-matched luciferase control early-stage erythroid cells promoting late-stage erythropoiesis rna-seq data revealed mkrn1in sf3b1-knockdown cells erythropoietin stimulates proliferation pe-cyanine7-il-3r mkrn1 strongly suggests severely impaired growth control late-stage erythroblasts myelodysplastic syndromes performed rna-seq analysis license information pmcid growth arrest induced proper splicing program ribosomal protein genes identify stage-specific defects
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